Abstract: A method and corresponding optical device to correct spherical aberration in an optical path caused by an electrically tunable lens (ETL) within the optical path. The method includes placing within the optical path and in working relationship with the ETL an aspherical correction lens dimensioned and configured to reduce spherical aberration in a light beam exiting the ETL.

Abstract: There is provided a spatial light modulator arranged to display a light modulation pattern including a hologram. The spatial light modulator includes a liquid crystal on silicon spatial light modulator having a plurality of pixels. The hologram has a plurality of pixels. The spatial light modulator includes a silicon backplane. Each pixel of the spatial light modulator includes a light-modulating element and a respective pixel circuit. Each pixel circuit is embedded in the silicon backplane. Each pixel circuit is arranged to drive the corresponding light-modulating element. Each pixel circuit is further arranged to combine a received pixel value of the hologram with a corresponding pixel value of the light processing function such that the light modulation pattern further includes the light processing function. The light processing function includes a lens function and/or a grating function.

Abstract: There is provided a driver for a spatial light modulator. The spatial light modulator comprises [m×n] pixels. The driver is arranged to receive input holograms each comprising [x×y] pixels, wherein m?x and n?y. The driver is further arranged to drive the spatial light modulator to display thereon output holograms each comprising [m×n] pixels by tiling each input hologram onto the pixels of the spatial light modulator to form an output hologram corresponding to each input hologram using a tiling scheme. The driver is arranged to use a first tiling scheme to display a first output hologram and a second tiling scheme to display a second output hologram. Each output hologram comprises a plurality of tiles of the input hologram. Each tiling scheme defines the size of each tile and the position of each tile on the pixels of the spatial light modulator.

Abstract: Accelerated methods and apparatuses for three-dimensional microscopy with structured illumination, in which focal planes of the sample are focused and each focal plane is illuminated in a plurality of phases sequentially with structured illumination light and the sample light emitted by the sample is recorded in a respective individual image. A resulting image having a resolution that is increased with respect to the individual images is reconstructed from the individual images to produce a super-resolved image stack, By reconstructing a resulting image from individual images of two different focal planes by approximation methods, said resulting image represents a sample plane that is situated between said focal planes, an image stack can be produced in a shorter period with less stress on the sample.

Abstract: Devices and methods for super-resolution optical microscopy are described. Devices include an optical multiplexer to develop an excitation/illumination optical beam that includes alternating pulses of different profiles. Devices also include a signal processing unit to process a sample response to excitation/illumination beam and to subtract the neighboring pulses of the different profiles from one another on a pulse-to-pulse basis. Devices can be incorporated in existing confocal microscopy designs. As the subtraction effectively reduces the volume of the response signal, the spatial resolution of the systems can be markedly improved as compared to previously known optical microscopy approaches.

Abstract: A microscope, including an x motor, a y motor, and a z axis focusing driving mechanism that drive a stage to move; at least one knob operatively coupled to the x motor or y motor or the z axis focusing driving mechanism selectively via a controller; and at least one button coupled to the controller in communication. The controller is configured to disconnect a normal operative coupling between the knob and the z axis focusing driving mechanism and establish an operative coupling between the knob and the x motor or y motor when receiving a predetermined button signal, and restore the normal operative coupling between the knob and the z axis focusing driving mechanism and disconnect the operative coupling between the knob and the x motor or y motor when no longer receiving the predetermined button signal or when receiving a next button signal.

Abstract: A method for high-resolution scanning microscopy of a sample in which a sample is illuminated at a point in or on the sample by means of illumination radiation. The point is imaged along an optical axis and according to a point spread function into a diffraction image on a spatially resolving surface detector that comprises detector pixels in which a diffraction structure of the diffraction image is resolved. The point is displaced relative to the sample in at least two scanning directions and pixel signals are read from the detector pixels in various scanning posi- tions, wherein the pixel signals are respectively assigned to that scanning position at which they were read out and adjacent scanning positions overlap one another and are disposed according to a scanning increment. An image of the sample having a resolution that is increased beyond a resolution limit of the imaging is generated from the read pixel signals and the assigned scanning positions, wherein a deconvolution is carried out.

Abstract: An observation device includes: a stage on which a vessel in which a subject is stored is installed; an image-forming optical system that includes an objective lens forming an image of the subject stored in the vessel; a scan control unit that moves the stage with respect to the image-forming optical system to scan each observation position in the vessel by the image-forming optical system; and an acceleration-determination-information acquisition unit that acquires at least one piece of information among information about the subject, information about the vessel, information about an observation method, or information about an observation condition. The scan control unit controls an acceleration of the stage on the basis of the at least one piece of information.

Abstract: A virtual image display device includes a display light guiding unit, and an image forming unit that emits image light to the display light guiding unit, the display light guiding unit includes a first light guiding unit that guides image light corresponding to a first angle of view, and a second light guiding unit that guides image light corresponding to a second angle of view, among angles of view of image light emitted from the image forming unit, and the first light guiding unit and the second light guiding unit respectively include incident side diffraction elements that take the image light beams into the inside, and emission side diffraction elements that emit the image light beams to the outside.

Abstract: An image reproducing device includes one or more processors. The processor acquires image group data including a plurality of images and tag information on at least one tag. The images relate to a biological sample along time series. The tag information relates to an operation on the biological sample and is associated with at least part of the images. The processor selects from the plurality of images using the tag information, images to be reproduced along the time series as reproduction selected images. The processor outputs to a display, data relating to the images for the reproduction selected images to be reproduced along time series.

Abstract: An apparatus for manufacturing a hologram includes a holographic optical element on which a first interference pattern of a first signal beam and a first reference beam is recorded and a second interference pattern of a second signal beam modulated by a Fourier lens and a second reference beam is recorded. Also, an apparatus for reconstructing a hologram by using the holographic optical element is provided.

Abstract: The effective focal length of an optical system can be electronically controlled using switchable wave plates in conjunction with polarized light.

Abstract: A multi-waveguide optical structure, including multiple waveguides stacked to intercept light passing sequentially through each waveguide, each waveguide associated with a differing color and a differing depth of plane, each waveguide including: a first adhesive layer, a substrate having a first index of refraction, and a patterned layer positioned such that the first adhesive layer is between the patterned layer and the substrate, the first adhesive layer providing adhesion between the patterned layer and the substrate, the patterned layer having a second index of refraction less than the first index of refraction, the patterned layer defining a diffraction grating, wherein a field of view associated with the waveguide is based on the first and the second indices of refraction.

Abstract: Diffractive optical structures, lens, waveplates, systems and methods of combinations of CDWs (cycloidal diffractive waveplates) and PVGs (polarization volume gratings) that result in high efficiency polarization-insensitive diffraction. Although our modelling and experiments were performed for structures with optical axis orientation periodic along one of the Cartesian coordinates parallel to the plane of the structure, the results are applicable to more complex structures such as diffractive waveplate lenses. The focusing performance of such structures can be predicted by considering the structure to be locally periodic along one axis.

Abstract: There is provided an optical element for counterfeit prevention that has both high counterfeit preventing property and designability by a multi-optical element structure. The optical element has a second layer (3) having a relief structure on a front surface, a first layer (2) disposed on the second layer (3), and a third layer (6) in a thin film interposed between the second layer (3) and the first layer (2) and formed along a front surface of the relief structure. The second layer (3) has a refractive index lower than a refractive index of the first layer (2) and the third layer (6) has a refractive index higher than the refractive index of the first layer (2). The optical element has at least a first region (4) and a second region (5) in a plan view. In the first region (4), an electromagnetic wave that enters from a side of the first layer (2) in a specific angle range is configured to be totally reflected.

Abstract: A system for illuminating a microscopy specimen includes illumination sources each of which is configured to emit a light that travels along an illumination path to illuminate the microscopy specimen placed on an optical detection path of an optical microscope. The system also includes optical elements in the illumination path of each of the illumination sources. The optical elements are configured to at least in part transform the light from each of the illumination sources into a light sheet illuminating the microscopy specimen and to vary a position of a waist of the light sheet from each of the illumination sources that illuminates the microscopy specimen. The optical elements for each of the illumination sources are configured such that the waist of the light sheet from each of the illumination sources are spatially aligned and illuminate a substantially coincident portion of the microscopy specimen.

Abstract: A method for scanning along a substantially straight line (3D line) lying at an arbitrary direction in a 3D space with a given speed uses a 3D laser scanning microscope having a first pair of acousto-optic deflectors deflecting a laser beam in the x-z plane (x axis deflectors) and a second pair of acousto-optic deflectors deflecting the laser beam in the y-z plane (y axis deflectors) for focusing the laser beam in 3D. Further, a method for scanning a region of interest uses a 3D laser scanning microscope having acousto-optic deflectors for focusing a laser beam within a 3D space defined by an optical axis (Z) of the microscope and X, Y axes that are perpendicular to the optical axis and to each other.

Abstract: An imaging system including a light source; a first focusing lens positioned to focus a beam from the light source to a beam waist at a predetermined location along an optical path of the beam in the imaging system; a beam splitter positioned relative to the first focusing lens to receive the beam from the first focusing lens and to create first and second beams; a second focusing lens positioned to receive the first and second beams output by the beam splitter, to focus the received first and second beams to a spot sized dimensioned to fall within a sample to be image, and further positioned to receive first and second beams reflected from the sample; an image sensor positioned to receive the light beams reflected from the sample; and a roof prism positioned in the optical path between the second focusing lens and the image sensor.

Abstract: An observation apparatus including: a light-source that emits illumination light and excitation light upward from below a specimen; and an image-capturing optical system having an objective lens that focuses, below the specimen, transmitted light, which is the illumination light that is emitted from the light-source, that is reflected above the specimen, and that has passed through the specimen, and fluorescence that is generated in the specimen that has been irradiated with the excitation light emitted from the light-source, wherein the light-source is disposed radially outside the objective lens.

Abstract: An array of optical resonators comprises at least a first type of optical resonators each having a resonant response to an optical field at a first wavelength, and a second type of optical resonators each having a resonant response to an optical field at a second wavelength, being different from the first wavelength. The resonant responses can be selected to reduce chromatic aberrations, or to shape a profile of a light beam, or to selectively switch a near field beam.