Patents Examined by Caralynne E Helm
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Patent number: 10952968Abstract: The solid preparation which improved the dissolution profile and the stability of the 6,7-unsaturation-7-carbamoyl morphinan derivative is provided. When 6,7-unsaturation-7-carbamoyl morphinan derivative, croscarmellose sodium and ferric oxide were contained, not titanium oxide in the solid preparations and the coating solid preparations, a dissolution rate after 15 minutes of the dissolution test is more than 85%, and stability, particularly, light stability can be improve.Type: GrantFiled: May 13, 2013Date of Patent: March 23, 2021Assignee: SHIONOGI & CO., LTD.Inventors: Akira Mashimo, Shunji Ichio, Yoshinori Tamura, Kouichi Noguchi
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Patent number: 10874622Abstract: Disclosed are nanoparticles for the delivery of a therapeutic agent or a diagnostic agent to a subject that include a chitosan and a polyphosphate, wherein the chitosan nanoparticles are coated with polylactic acid. Methods of delivering a therapeutic agent or a diagnostic agent to a subject for the treatment or prevention of a disease are also disclosed. For example, the treatment of ovarian cancer in a subject by inhibiting the expression of ZNF034 is disclosed.Type: GrantFiled: June 23, 2016Date of Patent: December 29, 2020Assignee: Board of Regents, The University of Texas SystemInventors: Burcu Aslan, Gabriel Lopez-Berestein, Anil K. Sood
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Patent number: 10857089Abstract: Suggested is a cosmetic composition comprising an anti-pollution agent selected from the group consisting of purple coneflower pressed juice, sclareolide, ginger root C02 extract, E/Z-2-benzylindene-5,6-dimethoxy-3,3-dimethylindan-1-one or mixtures thereof, in a working amount sufficient for (a) reducing or preventing air pollution induced gene expression, and/or (b) reducing or preventing a gene expression induced or inducible by polycyclic aromatic hydrocarbons, and/or (c) reducing or preventing air pollution-induced or air pollution-inducible skin damage.Type: GrantFiled: May 25, 2016Date of Patent: December 8, 2020Assignee: Symrise AGInventors: Jean Krutmann, Imke Meyer, William Johncock, Gerhard Schmaus, Marielle le Maire, Martina Herrmann
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Patent number: 10792312Abstract: A barrier layer and corresponding method of making provide anti-inflammatory, non-inflammatory, and anti-adhesion functionality for a medical device implantable in a patient. The barrier layer can be combined with a medical device structure to provide anti-adhesion characteristics, in addition to improved healing, non-inflammatory, and anti-inflammatory response. The barrier layer is generally formed of a naturally occurring oil, or an oil composition formed in part of a naturally occurring oil, that is at least partially cured forming a cross-linked gel. In addition, the oil composition can include a therapeutic agent component, such as a drug or other bioactive agent.Type: GrantFiled: September 20, 2017Date of Patent: October 6, 2020Assignee: ATRIUM MEDICAL CORPORATIONInventors: Joseph Ferraro, Lisa Rogers, Paul Martakos, Theodore Karwoski, Steve Herweck, Keith Faucher, Phillip McNamara
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Patent number: 10792250Abstract: The present invention relates to methods of forming miniemulsions and use of the miniemulsions as a delivery system for bioactive agents. In particular, the present invention relates to methods for forming a miniemulsion comprising providing a first phase comprising a hydrophilic surfactant, lipophillic surfactant and water and a second phase comprising a lipid, wherein said miniemulsion comprises emulsified particles having a mean diameter of 1 ?m or less.Type: GrantFiled: May 10, 2018Date of Patent: October 6, 2020Assignee: NS TECHNOLOGIES PTY LTDInventor: Desai Chiragkumar
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Patent number: 10750749Abstract: This invention relates to a process and an aqueous composition for killing spores. The process comprises contacting the spores with the aqueous composition for a sufficient period of time to effect a desired reduction (e.g., at least a 4 log reduction) in the number of spores capable of reproduction, metabolism and/or growth. The aqueous composition comprises water, peracetic acid and hydrogen peroxide. The concentration of peracetic acid in the water may be in the range from about 0.001 to about 60% by weight, or from about 0.001 to about 0.5% by weight. The weight ratio of peracetic acid to hydrogen peroxide may be in the range from about 0.001 to about 0.5.Type: GrantFiled: April 28, 2014Date of Patent: August 25, 2020Assignee: American Sterilizer CompanyInventors: Peter A. Burke, Mark James Leggett
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Patent number: 10744202Abstract: This invention provides for biocompatible, biodegradable eye drop pharmaceutical formulations useful for the treatment of ocular indications. In particular, tocopherols and their esters of low water solubility, notably ?-tocopheryl acetate, are exceptional vehicles for biocompatible, nonirritating topical eye drop formulations that provide sustained release of active agents.Type: GrantFiled: June 11, 2018Date of Patent: August 18, 2020Assignee: Ramscor, Inc.Inventors: Vernon G. Wong, Louis L. Wood
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Patent number: 10736829Abstract: The present invention relates primarily to the use of certain hydroxybenzoic acid amides or the salts or mixtures thereof for masking an unpleasant taste impression, preferably of a bitter, adstringent, dusty, dry, floury, rancid, metallic and/or cardboard taste or aftertaste, of one or more unpleasant-tasting peptides or of certain amino acid mixtures. The invention further relates to a corresponding method for masking unpleasant taste impressions and to novel preparations.Type: GrantFiled: September 30, 2015Date of Patent: August 11, 2020Assignee: SYMRISE AGInventors: Joachim Hans, Jakob Ley, Kathrin Langer, Susanne Paetz
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Patent number: 10709651Abstract: The present invention provides a composition containing component (A): a compound represented by the formula (1) wherein each symbol is as described in the DESCRIPTION, or a salt thereof, and component (B): at least one kind of inorganic powder. The composition can be produced conveniently, shows good dispersibility, and is superior in the sense of use such as moist feeling, feeling of close adhesion and affinity, and a coated film formed from the composition has good condition and is also superior in durability.Type: GrantFiled: June 23, 2017Date of Patent: July 14, 2020Assignee: AJINOMOTO CO., INC.Inventors: Nana Haraya, Shun Kobayashi
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Patent number: 10695428Abstract: The invention relates to the use of a photosensitive agent, or the precursor thereof, capable of producing reactive oxygen species (ROS) in the production of a drug that can be used for the photodynamic therapy (PDT)-based treatment of a disease related to a patient's stem cells, preferably epidermal stem cells.Type: GrantFiled: November 11, 2013Date of Patent: June 30, 2020Assignees: UNIVERSIDAD AUTONOMA DE MADRID, CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICASInventors: Jesus Espada Regalado, Elisa Carrasco Cerro, MarĂa Inmaculada Calvo Sanchez, Alfonso Blazquez-Castro, Angeles Juarranz De La Fuente
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Patent number: 10661095Abstract: Disclosed is the use of copper cysteamine nanoparticles for use in photodynamic cancer therapy. The disclosed methods of treatment utilize microwave radiation as a means for activating the copper cysteamine photosensitizer.Type: GrantFiled: August 25, 2016Date of Patent: May 26, 2020Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Wei Chen, Lun Ma
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Patent number: 10660869Abstract: The present invention relates to a lactate powder, more particularly a lactate powder having a lactate content of at least 20 wt. % and a water content of less than 3.5 wt. %, said powder comprising calcium cations as well as sodium cations. According to the invention, a calcium lactate powder combining high stability with excellent water dissolution properties can be obtained even though anhydrous calcium lactate represents the bulk of the powder if the powder additionally contains a certain amount of sodium lactate. The inventors have found that the presence of sodium lactate greatly improves the dissolution behavior of the anhydrous calcium lactate while maintaining the storage stability of the powder. The present inventors also established that the dissolution behavior of the powder can be further improved by the addition of a fast-dissolving carbohydrate material.Type: GrantFiled: July 31, 2013Date of Patent: May 26, 2020Assignee: PURAC BIOCHEM B.V.Inventors: Kees Van Der Voort Maarschalk, Heny Kusumawardani
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Patent number: 10639255Abstract: The invention relates to nail treatment system comprising at least one basecoat, at least one second coat, and optionally at least one topcoat, wherein the basecoat comprises water and at least one non-UV curable adhesive latex compound, and the second coat comprises at least one photocrosslinkable urethane (meth)acrylate and at least one (meth)acrylate monomer.Type: GrantFiled: December 17, 2014Date of Patent: May 5, 2020Assignee: L'OREALInventors: XianZhi Zhou, Chunhua Li, Hy Si Bui, Jean-Thierry Simonnet, Carl Riachi, Guillaume Kergosien
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Patent number: 10617794Abstract: Provided herein are methods comprising the use of a macroinitiator and application protocols to apply a hydrophilic coating to latex, or natural rubber, and compositions resulting from such methods. This coating results in e.g., an increased sense of lubrication when in contact with water or an aqueous solution.Type: GrantFiled: February 22, 2016Date of Patent: April 14, 2020Assignees: Trustees of Boston University, Boston Medical Center CorporationInventors: Mark W. Grinstaff, Stacy L. Chin, Ruiqing Xiao, Benjamin Goldman Cooper, Karen Buch, Ducksoo Kim
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Patent number: 10610463Abstract: A process for producing a cosmetic composition that includes step a) inkjet printing onto a basic cosmetic composition, using an inkjet printer, at least one fluid composition in an amount chosen so as to impregnate the basic composition over only a part of its thickness, and step b), after at least one sampling of the impregnated layer, repeating step a) while optionally modifying the fluid composition inkjet-printed.Type: GrantFiled: December 8, 2016Date of Patent: April 7, 2020Assignee: L'OREALInventors: Franck Giron, Henri Samain, Franck Girier Dufournier
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Patent number: 10603262Abstract: The present invention provides a composition containing component (A): a compound represented by the formula (1) wherein each symbol is as described in the DESCRIPTION, or a salt thereof and component (B): a cationic surfactant, which is superior in the usability during rinsing, which makes the hair surface after treatment smooth and free of dry feeling, provides a uniform touch feeling from the root of the hair to the tip thereof, and can be utilized as an aqueous cosmetic.Type: GrantFiled: June 23, 2017Date of Patent: March 31, 2020Assignee: AJINOMOTO CO., INC.Inventors: Nana Haraya, Shun Kobayashi
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Patent number: 10595612Abstract: A glove used for facial treatment is disclosed herein. The glove includes a hand opening, finger portions, a palm region, and at least one cosmetic pocket or cavity, at least one cap and at least one scrubbing pad. A User wears the glove on their hand and applies different types of cosmetic solutions to their skin that are filled into the cosmetic pockets or cavities located within the hollow finger portions of the glove. The caps of the cosmetic pockets can be opened to fill a cosmetic solution into the cavities and sealed to secure the cosmetic solution within said finger portions. At least a portion of glove, mainly a palm portion, is provided with at least one scrubbing pad that facilitates scrubbing and thus reduces clogged pores and puffiness. As a result, the glove facilitates facial treatment in a user friendly manner.Type: GrantFiled: April 27, 2018Date of Patent: March 24, 2020Inventor: Phinazee Brown
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Patent number: 10582711Abstract: A method for imparting to an article or product antimicrobial activity includes a step of applying an antimicrobial agent containing an antimicrobial polyaminosilane to the article or product. The antimicrobial polyaminosilane is prepared by subjecting an aminosilane monomer to a hydrolysis and condensation reaction. The antimicrobial polyaminosilane thus prepared is free of halide ions.Type: GrantFiled: September 14, 2016Date of Patent: March 10, 2020Assignee: LEADER OPTRONICS TECHNOLOGY CO., LTD.Inventors: Yu-Hui Huang, Shyh-Haur Su
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Patent number: 10556217Abstract: A method of forming cured microparticles includes providing a poly(glycerol sebacate) resin in an uncured state. The method also includes forming the composition into a plurality of uncured microparticles and curing the uncured microparticles to form the plurality of cured microparticles. The uncured microparticles are free of a photo-induced crosslinker. A method of forming a scaffold includes providing microparticles including poly(glycerol sebacate) in a three-dimensional arrangement. The method also includes stimulating the microparticles in the three-dimensional arrangement to sinter the microparticles, thereby forming the scaffold having a plurality of pores. A scaffold is formed of a plurality of microparticles including a poly(glycerol sebacate) thermoset resin in a three-dimensional arrangement. The scaffold has a plurality of pores.Type: GrantFiled: March 30, 2018Date of Patent: February 11, 2020Assignee: THE SECANT GROUP, LLCInventors: Steven Lu, Peter D. Gabriele, Julia Donnelly, Brian Ginn, Charles Brendan Nicholson, Jeremy J. Harris, Michael S. Flemmens
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Patent number: 10485230Abstract: A defoaming adjuvant comprises a solid particulate carrier and a polyalkylene glycol adsorbed on to the solid particulate carrier, where the polyalkylene glycol is a reaction product of an alkyl alcohol initiator with 1,2-butylene oxide and, optionally, propylene oxide.Type: GrantFiled: October 1, 2018Date of Patent: November 26, 2019Assignee: Dow Global Technologies LLCInventors: Ling Zhong, Jing Ji, Jianhai Mu