Abstract: A system and method for thought-based control of sexual stimulation devices using electroencephalography. In an embodiment, a training phase comprises placing electrodes on the head of a person, measuring electrical signals produced by the person's brain via the electrodes while the user engages in one or more thought-based training tasks, associating patterns of electrical activity in the person's brain while performing the tasks with controls of the sexual stimulation device. In an embodiment, an operation phase comprises generating control signals for the sexual stimulation device based on the associations when the patterns of electrical activity are detected by the electrodes. In some embodiments, machine learning algorithms are used to detect the patterns of electrical activity and make the associations. In some embodiments, data from other biometric sensors is included in the associations.

Abstract: Devices, systems and methods are provided for delivering coffee-derived volatiles to a user, particularly for the treatment of addiction. The coffee volatiles are selected and delivered by devices and systems which allow for concentrated delivery to the olfactory system of the user in a controlled manner. The olfactory system is the part of the sensory system used for smelling or olfaction. Olfaction of such coffee volatiles in this prescribed fashion stimulates the reward system of the brain such that a specific desired outcome is achieved. In some embodiments, the desired outcome is a reduction in addiction symptoms or curbing of a sensation of addiction withdrawal.

Abstract: An array of force sensors for determining a position of an object, detecting motion of object, and tracking motion of objects in 3D space are described herein. In particular, an array of force sensors can be used to monitor anatomical motion during medical procedures, such as head motion during cranial radiosurgery, to maintain a desired alignment with the anatomical feature. Alerts can be posted to the medical machine operator and the radiosurgery system or scanner can make compensatory adjustments to maintain the desired alignment either after suspension of treatment or dynamically during treatment. Methods of detecting a position, movement or tracking motion of an anatomical feature are also provided herein.

Abstract: A system and method for automated generation of control signals for sexual stimulation devices from usage history and other data. The system and method involve analyzing historical usage and other data for a user for a device or devices, processing the data through machine learning algorithms, and generating new or recombined patterns of stimulation based on the outputs from the machine learning algorithms. The resulting automated control signals represent partially or fully customized stimulation for a given user which evolve over time as the user continues to use the device or devices.

Abstract: Radiation treatment planning includes determining a number of beams to be directed into a target, determining directions (e.g., gantry angles) for the beams, and determining an energy level for each of the beams. The number of beams, the directions of the beams, and the energy levels are determined such that the beams do not overlap outside the target and the prescribed dose will be delivered across the entire target.

Abstract: The present invention relates to the use of an oxytocin receptor antagonist in females undergoing embryo transfer as part of an assisted reproductive technology. In particular, methods are provided for increasing ongoing implantation rate, increasing ongoing pregnancy rate, increasing clinical pregnancy rate, and/or increasing live birth rate in a female subject undergoing embryo transfer. Specifically, the antagonists are released in the luteal phase when the endometrium is receptive for embryo implantation and/or when the embryo has reached the blastocyst-stage.

Abstract: A minimally invasive neutron beam generating device is provided. The minimally invasive neutron beam generating device includes a proton accelerator, a target, and a neutron moderator. The proton accelerator is connected to a first channel, the target is located at one end of the first channel, and the neutron moderator covers the end of the first channel so that the target is embedded in the neutron moderator. In addition, the neutron moderator includes an accommodating element for accommodating a moderating substance, and the accommodating element is retractable.

Abstract: Disclosed is a device for magnetic action on living bodies to perform physiotherapy or stimulating effects on the tissues and internal organs of a human being or an animal to eliminate pain syndromes, stimulate the processes of vital activity and regeneration, and accelerate tissue recovery after invasive effects and injuries. The device comprises an oscillator connected to an inductor including a bifilar coil made as a flat disk. Two coil windings formed as concentrically arranged spirals of adjacent wires of different windings are placed on a dielectric substrate. When attached to the skin surface, the device allows to purposefully target pathogenic areas and organs located at 3-6 cm under the surface, while practically not affecting the tissues located near that surface. Suitable for clinical or home application, the device can be used for relieving pain of various etiologies, treating menstrual syndrome, hemorrhoids, joint diseases, healing injuries, and stimulating cell proliferation.

Abstract: The present disclosure provides systems and methods for adjusting a multi-leaf collimator (MLC) in a treatment process according to a treatment plan or a portion thereof. The MLC may include at least one closed leaf pair in the treatment process. The method may include: for each of the at least one closed leaf pair, determining an offset for the closed leaf pair; and causing the at least one closed leaf pair to move based on the determined at least one offset before or during the treatment process.

Abstract: The present invention is directed to a method for treating a bowel disease in a subject in need thereof, the method comprising inhibiting the activity of neurons of the insular cortex of the subject. Further provided is a system comprising a transcranial stimulation transducing coil for transcranial stimulation configured to provide a series of pulses to neurons of the insular cortex.

Abstract: A bariatric clamp may include substrate members overmolded in polymer forming first and second elongated portions with insert portions, and a bight portion having a flexible hinge wherein the inserts are engaged via a magnetic force to retain the clamp in a closed position to partition the stomach. In another embodiment, the bariatric clamp may include substrate members overmolded in polymer forming first and second elongated portions and a bight portion having a flexible hinge, wherein the first and second elongated portions are curved to conform to a curvature of a patient's stomach. In another embodiment, the bariatric clamp may include substrate members overmolded in polymer forming first and second elongated portions each having one or more suture portions formed via one or more recesses formed in the substrate members.

Abstract: Example implants, systems and methods using sensors for orthopedic surgical assessment and/or planning are described herein. An example system can include a wearable sensor device for pre-operative use by a patient before an orthopedic surgery to generate pre-operative sensor data. The system can also include an implantable sensor device (e.g., a bone implant) to generate and aggregate post-operative sensor data associated with the patient after the surgery. The system can retrieve the pre-operative sensor data and the post-operative sensor data and predict, analyze or assess an outcome of the surgery.

Abstract: Example methods and systems for quality-aware continuous learning for radiotherapy treatment planning are provided. One example method may comprise: obtaining an artificial intelligence (AI) engine that is trained to perform a radiotherapy treatment planning task. The method may also comprise: based on input data associated with a patient, performing the radiotherapy treatment planning task using the AI engine to generate output data associated with the patient; and obtaining modified output data that includes one or more modifications made by a treatment planner to the output data. The method may further comprise: performing quality evaluation based on (a) first quality indicator data associated with the modified output data, and/or (b) second quality indicator data associated with the treatment planner. In response to a decision to accept, a modified AI engine may be generated by re-training the AI engine based on the modified output data.

Abstract: A system and method for controlling the speed of operation of sexual stimulation devices from videos of sexual activity using a less computationally-intensive method of estimating movement speed from a video. In an embodiment, the system and method involve estimating movement in a video using pixel-by-pixel color change over time, calculating a rate of color change in the video, estimating a speed of movement in the video from the rate of color change, and applying an algorithm to convert the estimated speed of movement in the video to a speed of operation of a sexual stimulation device.

Abstract: A method and apparatus for treatment of cancer is provided. The method can include systemic delivery of A3 selective adenosine receptor (A3AR) agonists CI-IB-MECA, cordycepin or similar drugs and providing simultaneous pulsed Electric Field (EF) stimulation to the treatment area. EF stimulation can be delivered in three orthogonal directions, which significantly increases expression of A3ARs on the cellular membranes and allows achieving a downstream apoptotic signal that is 4-6 fold stronger than the signal achieved with the agonist drugs alone.

Abstract: A system and method for a sexual aid device having a sheath in which to dispose the penis of the first and second users and an apparatus to affix the sheath around the penis of the first user to prevent it from sliding off, a ring that may be placed around the genitals, and a garment which is attached to the sheath and/or ring and placed around the waist, legs, or other body part.

Abstract: Systems and method for generating and executing volumetric modulated arc therapy (“VMAT”) plans are provided. In some aspects, the method includes receiving a representation of a subject comprising information related to target and non-target volumes of interest, and generating an objective function based on the representation of the subject, wherein the objective function accounts for dynamic collimator rotation. The method also includes performing an iterative optimization process, using the objective function, to generate a dynamic collimator VMAT plan, and generating a report in accordance with the dynamic collimator VMAT plan.

Abstract: Methods and apparatus are provided for affecting an appearance of skin by harvesting small portions of tissue from a donor (first) site and applying them at a recipient (second) site. A plurality of micrografts can be formed from a piece of graft tissue and attached to a dressing material. The dressing material can then be expanded to increase a separation distance between the micrografts, and the dressing material having spaced-apart micrografts attached thereto can be applied to a prepared recipient site. An apparatus can be provided that expands the dressing material using a pressurized fluid. A further method can include providing a suspension of small portions of graft tissue in a solution. The solution can be injected into blisters formed at a recipient (second) site and the tissue portions allowed to attach and proliferate. A method and apparatus can also be provided for forming corresponding blisters at a donor site and at a recipient site.

Abstract: The present invention provides a device for rejuvenating a region of skin or mucosal tissue, comprising: a pulsed electromagnetic frequency generator; a plurality of electrodes in communication with the pulsed electromagnetic frequency generator and an RF tissue diathermy device. The electrodes apply the pulsed electromagnetic power and the RF tissue diathermy to the tissue, heating it such that one portion of the region of mucosal tissue is maintained at a predetermined temperature range T1 while another portion of the region of mucosal tissue is at least temporarily maintained at predetermined temperature range T2.

Abstract: Methods and systems are disclosed for capturing sensor data collected by a personal massaging device with associated sensors, analyzing the data, determining biofeedback data based on the sensor data, and according to some embodiments generating a sexual response profile based on the biofeedback data and a model of human sexual response. Data may be collected and analyzed for a number of uses, including but not limited to: (1) studying human sexual response, (2) adjusting outputs of the personal massaging device based on preset conditions, (3) treating sexual dysfunction conditions, and (4) improving sexual experiences.