Abstract: Apparatus for planning a diffusing alpha-emitter radiation therapy (DaRT) treatment session. The apparatus includes an output interface and a memory configured with a plurality of tables which provide an accumulated measure of radiation over a specific time period, due to one or more types of DaRT radiotherapy sources which emit daughter radionuclides from the source, for a plurality of different distances and angles relative to the DaRT radiotherapy source. In addition, a processor is configured to receive a description of a layout of a plurality of DaRT radiotherapy sources in a tumor, to calculate a radiation dose distribution in the tumor responsive to the layout, using the tables in the memory, and to output feedback for the treatment responsive to the radiation dose distribution, through the output interface.

Abstract: Apparatus for planning a diffusing alpha-emitter radiation therapy (DaRT) treatment session. The apparatus includes an output interface and a memory configured with a plurality of tables which provide an accumulated measure of radiation over a specific time period, due to one or more types of DaRT radiotherapy sources which emit daughter radionuclides from the source, for a plurality of different distances and angles relative to the DaRT radiotherapy source. In addition, a processor is configured to receive a description of a layout of a plurality of DaRT radiotherapy sources in a tumor, to calculate a radiation dose distribution in the tumor responsive to the layout, using the tables in the memory, and to output feedback for the treatment responsive to the radiation dose distribution, through the output interface.

Abstract: An appliance includes a handle, a speculum tube extending axially from the handle as far as a distal end where it has an opening, a video viewing system having a lens arranged in the speculum tube and a transmission device connected to the lens and connectable to a remote viewing screen, and a lens support for keeping the lens in a predetermined position with respect to the speculum tube, in which position the lens is near the opening and opposite the space situated beyond the opening, characterized in that the speculum tube has an end part and a main part extending between the end part and the handle, the end part being arranged around the support and delimiting the opening, the end part being elastically deformable and the main part being rigid.

Abstract: Systems, devices, and methods described herein relate to multi-sensory presentation devices, including virtual reality (VR) devices, visual display devices, sound devices, haptic devices, and other forms of presentation devices, that are configured to present sensory elements, including visual and/or audio scenes, to a user. In some embodiments, one or more sensors including electroencephalography (EEG) sensors and a photoplethysmography (PPG) sensors, e.g., included in a brain-computer interface, can measure physiological data of a user to monitor a state of the user during the presentation of the visual and/or audio scenes. Such systems, devices, and methods can adapt one or more visual and/or audio scenes based on user physiological data, e.g., to control or manage the state of the user.

Abstract: A method and system for generating a voxel-based quadratic penalty model for automatic intensity modulated radiation therapy (IMRT) treatment planning are disclosed herein. A computing system generates an initial assignment of threshold values to a penalty function for IMRT treatment planning. The computing system receives an update to a dose value associated with the IMRT treatment planning. The computing system dynamically updates the threshold values based on the updated dose value. The computing system continues to iterate the threshold values based on further updated dose values.

Abstract: Methods and apparatus are provided for planning and delivering radiation treatments by modalities which involve moving a radiation source along a trajectory relative to a subject while delivering radiation to the subject. In some embodiments the radiation source is moved continuously along the trajectory while in some embodiments the radiation source is moved intermittently. Some embodiments involve the optimization of the radiation delivery plan to meet various optimization goals while meeting a number of constraints. For each of a number of control points along a trajectory, a radiation delivery plan may comprise: a set of motion axes parameters, a set of beam shape parameters and a beam intensity.

Abstract: A system is disclosed. The system has an accessory control module, comprising computer-executable code stored in non-volatile memory, a memory for storing instructions and a processor for executing the instructions, a user device of a user, and an accessory configured to communicate with the user device. The accessory control module, the memory and the processor, the user device, and the accessory are configured to accumulate receipt of one or more input parameters, determine whether an accumulation satisfies a preset condition, wherein the preset condition includes at least one of a preset receiving quantity of the one or more input parameters, a preset receiving sum of values of the one or more input parameters, or a preset time duration of the accumulation, and in response to the accumulation satisfying the preset condition, send a control signal to actuate the accessory to perform a series of predefined acts, wherein the series of predefined acts is configured to sexually stimulate the user.

Abstract: Disclosed embodiments provide a portable sex article. The article includes a soft hollow case (which, in some embodiments, is a pillow case). The case is specially designed with a holster formed on a first side the case. The holster is adapted to secure a sex simulation device such as an artificial vagina or dildo. The holster extends into an interior region of the case, and may have a securing mechanism such as elastic bands or a hook-and-loop fastener to secure a sex simulation device in place. A human image is imparted on the case, such as by a textile printing process. The human image can be a photograph or illustration. The human image includes a rendering of an anatomical orifice, such as an anus, vagina, and/or mouth. The human image is oriented such that the anatomical orifice is aligned with the holster.

Abstract: An electronic sensory simulation system including a display screen that simulates visual images or videos with a smell and audio simultaneously. The device effectively includes an electronic sensory simulation system with a docking station that may allow the system to be portable. The electronic sensory simulation system may include a sensory unit assembly which includes a display screen, at least one speaker, at least one scent diffusing mechanism, a user interface, and an input port. The electronic sensory simulation system may further have a docking station so that the sensory unit assembly can be portable or used in a fixed location.

Abstract: Magnetic nanoparticles for use in a magnetic hyperthermia therapeutic treatment, prophylactic treatment or diagnosis method, wherein the magnetic nanoparticles are administered to a body part of an individual and the body part is exposed to a magnetic field oscillating at a high frequency and at a medium and/or low frequency, wherein the high frequency is 1 MHz at the most, the medium frequency is lower than the high frequency, and the low frequency is lower than the high frequency and lower than the medium frequency when it is present.

Abstract: Methods, systems, and compositions for maintaining functioning drainage blebs to reduce intraocular pressure (IOP) of an eye being treated for glaucoma. The methods, systems, and compositions feature the combination of a minimally invasive glaucoma surgery (MIGS) implant or procedure and the application of beta radiation to the bleb. The beta radiation can function to inhibit or reduce the inflammation and/or fibrogenesis that typically occurs after insertion of a MIGS implant and leads to bleb failure. By reducing inflammation and/or fibrogenesis, the MIGS implant and the blebs can remain functioning appropriately.

Abstract: This invention relates generally to a medical device, and more specifically, to a vaginal surgical apparatus. In one embodiment, a vaginal device includes, but is not limited to, a shaft, the shaft including at least a space to at least partially accommodate a cervix; and a slot to secure a tenaculum; and a stopper that is positionably adjustable along at least a portion of a length of the shaft.

Abstract: A mask includes a body having an interior surface defining a cavity shaped to receive a user's nose. An exterior surface of the body is exposed to an ambient environment. The body includes an inlet in fluid communication with the cavity and a one-way exhaust valve in fluid communication between the cavity and the ambient environment. A therapeutic substance dispenser is in fluid communication with the cavity. In one embodiment, a nasal aromatic decongestant is disposed in the therapeutic dispenser. A mask includes an upper nasal cavity separate from a lower oral cavity, with an inlet in fluid communication with only the upper nasal cavity. A medicament delivery assembly, and methods for the use thereof, are also provided.

Abstract: Methods, systems and apparatus for inducing and verifying the level of neural entrainment at any target frequency, through a combination of biofeedback mechanisms, data analysis, and modulation of synergistic combinations of adaptable stimuli.

Abstract: The present invention relates to methods and devices to consolidate memory and/or cognitive functions by monitoring brain rhythms and delivering a stimulus at an appropriate stage of sleep cycle.

Abstract: A device for repetitive nerve stimulation for development of muscle via inductive magnetic fields, having a stimulation coil in a plastic housing. A pulse generator may be provided for electrically actuating the stimulation coil.

Abstract: A system and method for automated generation of control signals for sexual stimulation devices from usage history and other data. The system and method involve analyzing historical usage and other data for a user for a device or devices, processing the data through machine learning algorithms, and generating new or recombined patterns of stimulation based on the outputs from the machine learning algorithms. The resulting automated control signals represent partially or fully customized stimulation for a given user which evolve over time as the user continues to use the device or devices.

Abstract: Better Pareto dose distributions for multi-criteria optimization of treatment plans can be obtained by obtaining at least one reference dose function designed to result in an acceptable reference dose distribution, defining a multi-criteria optimization problem including the at least one reference dose function as at least one optimization function, performing at least two optimization procedures based on the multi-criteria optimization problem to generate a set of at least two possible treatment plans, obtaining a treatment plan to be used for treating the patient, based on the set of possible treatment plans, by selecting one plan or by combining plans.

Abstract: Devices, materials, compounds, systems, and processes for Cherenkov-Activated Nuclear-Targeted Photodynamic Therapy that involves generating Cherenkov light within the tissue of a target volume and using this light to activate photosensitizing material that is located in the nucleus of cells of the target volume.

Abstract: A process for calibrating a glucose sensor under sterile conditions includes providing separate, sterile, glucose-containing calibration fluids, each having a different glucose concentration, and in turn providing these fluids to a sensing zone containing a sensing probe of a glucose sensor. Each solution is typically, in turn, propelled into the sensing zone, thus flushing out used fluid already present in the sensing zone. The process provides rapid calibration of a glucose sensor in a sterile fashion and is therefore appropriate for point-of-use calibration.