Patents Examined by Marjan Fardanesh
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Patent number: 11517224Abstract: Implantable device for measuring the glucose concentration of a body fluid when implanted, the implantable device comprising a glucose measurement unit, the glucose measurement unit comprising a first light source configured to emit light towards a light transmissive part of a housing of the device and a first optical sensor configured to detect light returned through the light transmissive part from the first light source, and output a first electrical signal based on the detected light; and a wireless communication module configured to wirelessly communicate with an external wireless communication device, wherein the wireless communication module is configured to wirelessly transmit a signal based on the first electrical signal to the external wireless communication device.Type: GrantFiled: November 15, 2018Date of Patent: December 6, 2022Assignee: SanofiInventor: Thomas Klemm
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Patent number: 11504002Abstract: Systems and method for monitoring patient physiological data are presented herein. In one embodiment, a physiological sensor and a mobile computing device can be connected via a cable or cables, and a processing board can be connected between the sensor and the mobile computing device to conduct advanced signal processing on the data received from the sensor before the data is transmitted for display on the mobile computing device.Type: GrantFiled: April 23, 2020Date of Patent: November 22, 2022Assignee: Masimo CorporationInventors: Bilal Muhsin, Sujin Hwang, Benjamin C. Triman
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Patent number: 11504035Abstract: Some embodiments described herein relate to an apparatus including a light source configured to transmit an excitation optical signal to an implanted sensor and a detector configured to detect an analyte-dependent optical signal emitted from an implanted sensor. The apparatus can include a lens configured to focus at least a portion of the analyte-dependent optical signal onto the detector.Type: GrantFiled: March 4, 2019Date of Patent: November 22, 2022Assignee: Profusa, Inc.Inventors: Gregory J. Kintz, William A. McMillan, Natalie A. Wisniewski
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Patent number: 11490816Abstract: The present invention is directed to an apparatus (10) for reliable quantitative measurement of a fluorescent blood analyte in tissue (12) comprising: at least one light source (14), the light source (14) emitting excitation light at least at a first wavelength range between 350 nm and 450 nm to the tissue (12); a detection unit (16), the detection unit (16) measuring: a) a portion of the fluorescent light emitted by the fluorescent blood analyte excited at the first wavelength range; and b) a portion of the auto fluorescence emitted by the tissue (12); and/or c1) a portion of the remitted excitation light at the first wavelength range, and c2) a portion of the remitted light at a second wavelength range; and a control unit (18), the control unit (18) operating the light source (14) and detection unit (16). The present invention is further directed to a method for quantitative measurement of a fluorescent blood analyte in tissue (12).Type: GrantFiled: February 17, 2016Date of Patent: November 8, 2022Assignee: FerroSens GmbHInventors: Herbert Stepp, Georg Hennig, Christian Homann
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Patent number: 11484215Abstract: A blood pressure measuring apparatus for measuring a blood pressure of a subject using a cuff attached to the subject is equipped with an inflating mechanism—configured to increase an inner pressure of the cuff, a processor and a memory—configured to store instructions that is readable by the processor. As the instructions are executed by the processor, the blood pressure measuring apparatus-acquires a pulse rate of the subject while causing the inflating mechanism to increase the inner pressure of the cuff at a prescribed inflation speed, and compares the pulse rate as acquired to a prescribed pulse rate. The blood pressure measuring apparatus causes the inflating mechanism to increase the inner pressure of the cuff at an inflation speed that is lower than the prescribed inflation speed if the pulse rate as acquired is less than the prescribed pulse rate.Type: GrantFiled: March 20, 2018Date of Patent: November 1, 2022Assignee: NIHON KOHDEN CORPORATIONInventor: Yoshiharu Kikuchi
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Patent number: 11484262Abstract: A composite thread includes first and second segments joined to each other. The first segment comprises a functional segment that interacts with an environment of the thread. The second segment communicates information between the first segment and a point external to said composite thread.Type: GrantFiled: July 29, 2016Date of Patent: November 1, 2022Assignee: Trustees of Tufts CollegeInventors: Sameer Sonkusale, Pooria Mostafalu
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Patent number: 11484190Abstract: A medical capsule is equipped with a sensor device having light emitting and light receiving elements. The sensor device can detect blood on the basis of light absorption properties of the blood. The capsule has a casing forming a recess or gap at its outer surface. The recess has a pre-selected width which represents a fixed measuring track between the light emitting and light receiving elements being arranged at opposing sides of the recess or gap when seen in its width direction. The medical capsule also has a shielding plate/layer/membrane arranged at least at or near the bottom of the recess or gap and extending along the width direction of the recess or gap preferably to exceed the recess at both sides into its width direction to prohibit emitted light from bypassing the recess via the casing material of the capsule.Type: GrantFiled: May 29, 2017Date of Patent: November 1, 2022Inventors: Marc O. Schurr, Sebastian Schostek
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Patent number: 11478170Abstract: A tissue oximetry device utilizes at least three or at least four different wavelengths of light for collection of reflectance data where the different wavelengths are longer than 730 nanometers. The three or four wavelengths are utilized to generate a range of reflectance data suited for accurate determination of oxygenated hemoglobin and deoxygenated hemoglobin concentrations. The relatively long wavelengths decrease optical interference from certain dyes, particularly methylene blue and PVPI, which may be present on tissue being analyzed for viability and further enhance the generation of accurate reflectance data. The wavelengths are 760 nanometers, 810 nanometers, and 850 nanometers, or 760 nanometers, 810 nanometers, 850 nanometers, and 900 nanometers.Type: GrantFiled: July 2, 2019Date of Patent: October 25, 2022Assignee: ViOptix, Inc.Inventors: Kate Leeann Bechtel, Lester John Lloyd
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Patent number: 11478151Abstract: Disclosed are fiber optic devices and related methods that allow for measurement of blood flow and oxygenation in real time. These devices have particular application to the spinal cord. Such devices have applicability in, for example, the care of military members sustaining combatant and noncombatant spinal injuries, as well as to civilians. The devices also have utility in the acute and subacute management of spine trauma, enhancing the efficacy of interventions aimed at the prevention of secondary ischemic injury, and ultimately improving neurologic outcome.Type: GrantFiled: August 1, 2018Date of Patent: October 25, 2022Assignees: The Trustees of the University of Pennsylvania, The Research Foundation for The State University of New YorkInventors: Thomas F. Floyd, Arjun G Yodh, Rickson C Mesquita
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Patent number: 11471133Abstract: An apparatus for estimating blood concentration of an analyte may include a sweat collector configured to collect sweat from a skin surface of a user. The apparatus may include an optical sensor configured to emit light rays of different wavelengths towards the collected sweat, and detect an optical signal reflected by the collected sweat. The apparatus may include a processor configured to estimate the blood concentration of the analyte based on the detected optical signal.Type: GrantFiled: September 11, 2019Date of Patent: October 18, 2022Assignee: SAMSUNG ELECTRONICS CO., LTD.Inventors: Sang Kyu Kim, Jun Ho Lee
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Optical device for non-invasive continuous monitoring of blood glucose level and HbA1c concentration
Patent number: 11452469Abstract: A sensor device which is adapted for detecting target molecules in-vitro and in-vivo, comprises a MIR source emitting in 2 um to 10 um range for exciting the target species and a probe beam with orthogonal polarizations and split frequencies in the KHz. to MHz range. The probe beam measures the effects of specie concentration change and of its excitation. The evanescent fields of the orthogonally polarized beams in the probe beam undergo differential phase shifts when target species concentration changes in epidermis or when its refractive index changes due to photo-thermal excitation by the MIR beam. The phase shift is directly proportional to concentration change and refractive index change and are measured using a heterodyne interferometer operating at the same frequency as the split frequency. The measured phase shift can be related to specie concentration change in target volume.Type: GrantFiled: September 24, 2021Date of Patent: September 27, 2022Inventor: Arun Ananth Aiyer -
Patent number: 11445924Abstract: An implantable vital sign sensor including a housing including a first portion, the first portion defining a first open end, a second open end opposite the first end, and a lumen there through, the first portion being sized to be implanted substantially entirely within the blood vessel wall of the patient. A sensor module configured to measure a blood vessel blood pressure waveform is included, the sensor module having a proximal portion and a distal portion, the distal portion being insertable within the lumen and the proximal portion extending outward from the first open end.Type: GrantFiled: August 1, 2019Date of Patent: September 20, 2022Assignee: Thomas Jefferson UniversityInventor: Jeffrey I. Joseph
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Patent number: 11439351Abstract: Certain embodiments described herein pertain to optical sensors, systems and methods for continuous glucose monitoring. In some embodiments, methods of preparing a layered optical sensor are disclosed. The optical sensor can be formed by laminating a plurality of sheets together to form a final sensor. In some embodiments, the sensor tip comprises a oxygen conduit, an enzymatic layer, and an sensing layer. In some embodiments, the sensor includes a plurality of waveguides configured to direct light to and from a target material, such as an oxygen sensing polymer. Systems are also disclosed for an adhesive system for attaching an optical sensor-transmitter system. Methods and systems are also disclosed for a sensor inserter system. The inserter can include a lancet tip that includes a convex feature attached to a first surface of the lancet tip.Type: GrantFiled: November 16, 2018Date of Patent: September 13, 2022Assignee: Metronom Health, Inc.Inventor: Troy M. Bremer
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Patent number: 11432727Abstract: There is included an apparatus and system including video capture code configured to control a camera of a mobile phone to capture a video of at least a portion of skin, extraction code configured to extract at least one photoplethysmogram (PPG) signal from the video, determination code configured to determine a peripheral oxygen saturation (SpO2) value based on the PPG signal with respect to a blood flow at the portion of skin, and display code configured to control a display of the mobile phone to display the SpO2 value.Type: GrantFiled: May 8, 2020Date of Patent: September 6, 2022Assignee: TENCENT AMERICA LLCInventors: Lianyi Han, Chao Huang, Xiaozhong Chen, Zhimin Huo, Shih-Yao Lin, Hui Tang, Tao Yang, Kun Wang, Wei Fan
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Patent number: 11432771Abstract: An physiological measurement device provides a device body having a base, legs extending from the base and an optical housing disposed at ends of the legs opposite the base. An optical assembly is disposed in the housing. The device body is flexed so as to position the housing over a tissue site. The device body is unflexed so as to attach the housing to the tissue site and position the optical assembly to illuminate the tissue site. The optical assembly is configured to transmit optical radiation into tissue site tissue and receive the optical radiation after attenuation by pulsatile blood flow within the tissue.Type: GrantFiled: June 28, 2021Date of Patent: September 6, 2022Assignee: Masimo CorporationInventors: Yassir Abdul-Hafiz, Ammar Al-Ali, Kevin Forrest, Eugene Mason, John Schmidt, Virginia Thanh Ta
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Patent number: 11426125Abstract: An physiological measurement device provides a device body having a base, legs extending from the base and an optical housing disposed at ends of the legs opposite the base. An optical assembly is disposed in the housing. The device body is flexed so as to position the housing over a tissue site. The device body is unflexed so as to attach the housing to the tissue site and position the optical assembly to illuminate the tissue site. The optical assembly is configured to transmit optical radiation into tissue site tissue and receive the optical radiation after attenuation by pulsatile blood flow within the tissue.Type: GrantFiled: April 8, 2019Date of Patent: August 30, 2022Assignee: Masimo CorporationInventors: Yassir Abdul-Hafiz, Ammar Al-Ali, Kevin Forrest, Eugene Mason, John Schmidt, Virginia Thanh Ta
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Patent number: 11419528Abstract: A method for determining oxygen saturation includes emitting light from sources into tissue; detecting the light by detectors subsequent to reflection; and generating reflectance data based on detecting the light. The method includes determining a first subset of simulated reflectance curves from a set of simulated reflectance curves stored in a tissue oximetry device for a coarse grid; and fitting the reflectance data points to the first subset of simulated reflectance curves to determine a closest fitting one of the simulated reflectance curves. The method includes determining a second subset of simulated reflectance curves for a fine grid based on the closest fitting one of the simulated reflectance curves; determining a peak of absorption and reflection coefficients from the fine grid; and determining an absorption and a reflectance coefficient for the reflectance data points by performing a weighted average of the absorption coefficients and reflection coefficients from the peak.Type: GrantFiled: February 20, 2019Date of Patent: August 23, 2022Assignee: ViOptix, Inc.Inventors: Kate LeeAnn Bechtel, H. Keith Nishihara
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Patent number: 11412940Abstract: The present invention provides a dynamic measurement device with a blood pressure determination function, comprising: a heartbeat sensing module disposed on the chest area of a user wherein the heartbeat sensing module comprising a heart sound sensor for obtaining heartbeat signals; a pulse sensing module disposed on a limb area of the user, the pulse sensing module comprising a pulse wave sensor for obtaining pulse signals; and a data calculating module for calculating a mean arterial pressure and a value of systolic blood pressure and diastolic blood pressure based on the heartbeat signals and pulse signals. In addition to dynamically monitoring the blood pressure of a user for 24 hours, the present invention can dynamically monitor the heart sounds of the user for 24 hours individually in order to monitor user's physical condition. Therefore, the present invention has important medical meanings.Type: GrantFiled: November 30, 2017Date of Patent: August 16, 2022Assignees: BIV MEDICAL, LTD.Inventors: Shiming Lin, Shih-Wei Chiang, Cheng-Yan Guo, Tai-Cun Lin, Wei-Chih Huang, Chun-Nan Chen, Ya-Ting Chang
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Patent number: 11406295Abstract: Methods and systems for sensor calibration and sensor glucose (SG) fusion are used advantageously to improve the accuracy and reliability of orthogonally redundant glucose sensor devices, which may include optical and electrochemical glucose sensors. Calibration for both sensors may be achieved via fixed-offset and/or dynamic regression methodologies, depending, e.g., on sensor stability and Isig-Ratio pair correlation. For SG fusion, respective integrity checks may be performed for SG values from the optical and electrochemical sensors, and the SG values calibrated if the integrity checks are passed. Integrity checks may include checking for sensitivity loss, noise, and drift. If the integrity checks are failed, in-line sensor mapping between the electrochemical and optical sensors may be performed prior to calibration.Type: GrantFiled: July 25, 2019Date of Patent: August 9, 2022Assignee: MEDTRONIC MINIMED, INC.Inventors: Andrea Varsavsky, Xiaolong Li, Mike C. Liu, Yuxiang Zhong, Ning Yang
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Patent number: 11406321Abstract: A sweat sensing device includes a flexible body having a first, outwardly facing surface and a second, skin facing surface and a sweat channel formed in the body, the sweat channel having a first end defining a fluid inlet and a second end. A biochemical assay well formed in the sweat channel and an assay material is disposed in the biochemical assay well, the assay material positioned to react with sweat traveling through the sweat channel and to provide one of a visual indicator and an indicator detectable by a camera and connected processor of the flow of the sweat in the sweat channel.Type: GrantFiled: July 24, 2018Date of Patent: August 9, 2022Assignee: Epicore Biosystems, Inc.Inventors: Jeffrey B. Model, Roozbeh Ghaffari, Alexander J. Aranyosi, Stephen P. Lee, Milan S. Raj