Abstract: A conformal patch device can be provided to a patient. The patch device can include sensors configured to be positioned over a chest of a patient. The sensors can include PPG sensors, ECG sensors, and SCG sensors. The conformal patch device can to adhere to a single continuous area of the chest. Some sensors may attached to a viscoelastic substrate to achieve mechanical isolation from other patch components. The conformal patch device can capture measurements from the sensor doing a time window sufficient enough to detect disordered breathing. The system can determine disordered breathing and related cardiorespiratory parameters during the time window for the patient using the sensor measurements.

Abstract: The present invention will provide a device in which a movement-impairing episode, such as freezing of gait, is overcome by electrically monitoring and stimulating the individual as soon as the episode is anticipated. The device will be simple and effective when used by individuals suffering from diseases such as Parkinson's Disease without the side effects of oral treatments. This is accomplished through a signal sensing unit, a signal processing unit, a signal generating unit, and an actuation unit.

Abstract: Techniques are provided for generating and processing compressed sensor data. Sensor signals can be collected using one or more sensors. The sensor signals can be compressed using a compression data structure. In some instances, the compressed signal corresponds to a sampling rate at or below the Nyquist sampling rate. The compressed signal can be compared to one or more templates. Events within the compressed signal can be detected and characterized based on the comparison.

Abstract: Transcutaneous electrical nerve stimulation devices and magnetic stimulation devices are disclosed, along with methods of treating medical disorders using energy that is delivered noninvasively by such devices. The disorders comprise migraine and other primary headaches such as cluster headaches, including nasal or paranasal sinus symptoms that resemble an immune-mediated response (“sinus” headaches). The devices and methods may also be used to treat rhinitis, sinusitis, or rhinosinusitis, irrespective of whether those disorders are co-morbid with a headache. They may also be used to treat other disorders that may be co-morbid with migraine or cluster headaches, such as anxiety disorders. In preferred embodiments of the disclosed methods, one or both of the patient's vagus nerves are stimulated non-invasively. In other embodiments, parts of the sympathetic nervous system and/or the adrenal glands are stimulated.

Abstract: Systems, methods, and interfaces are described herein for assisting a user in noninvasive evaluation of patients for cardiac therapy and noninvasive evaluation of cardiac therapy being delivered. The systems, methods, and interfaces may provide graphical representations of cardiac electrical activation times about one or more portions of human anatomy and one or more cardiac health metrics.

Abstract: An intravascular blood pump having a rotatable shaft carrying an impeller and a housing with an opening through which the shaft extends with the impeller positioned outside the housing. The shaft and the housing have surfaces forming a circumferential gap which converges towards the impeller-side end of the gap and which has a minimum gap width of preferably no more than 5 ?m, more preferably no more than 2 ?m.

Abstract: A method of modifying cardiac tissue behavior, comprising applying a therapeutically effective electric field having an effect of modifying protein activation levels of at least one protein, and repeatedly applying the field at time intervals timed to increase the activation levels of the at least one protein beyond an activation level achieved by natural and/or paced excitation of the muscle without the application, to an extent about at least as high as a decay of the activation between applications of the field.

Abstract: A sensory supplement medical device, including a stimulation device configured to implement a first functionality of the sensory supplement medical device corresponding to the providing of sensory supplement to a recipient to evoke a sensory percept, wherein the sensory supplement medical device is configured to implement a secondary functionality different from the first functionality, and the sensory supplement medical device is configured to migrate the second functionality to a device remote from the sensory supplement medical device.

Abstract: A control device (100) for controlling the rotational speed (nVAD(t)) of a non-pulsatile ventricular assist device, VAD, (50) uses an event-based within-a-beat control strategy, wherein the control device is configured to alter the rotational speed of the VAD within the cardiac cycle of the assisted heart and to synchronize the alteration of the rotational speed with the heartbeat by at least one sequence of trigger signals (?(t)) that is related to at least one predetermined characteristic event in the cardiac cycle. Further, a VAD (50) for assistance of a heart comprises the control device (100) for controlling the VAD, wherein the VAD is preferably a non-pulsatile rotational, for example catheter-based, blood pump.

Abstract: Methods and systems methods for continuously monitoring a patient for cardiac electrical abnormalities including atrial fibrillation, asystole, ventricular fibrillation and tachycardia.

Abstract: An implantable neurostimulation system comprises a stimulation delivery lead and a neurostimulator. The stimulation delivery lead is coupled to an electrode. The neurostimulator is adapted to deliver a neurostimulation signal to the subject and comprises a microprocessor. The microprocessor is programmed to identify a stimulation operating window for the therapy including a first threshold and a second threshold. The second threshold comprises an awake level and an asleep level. Identifying the stimulation operating window comprises titrating a stimulation setting of the neurostimulator while the subject is awake until the first threshold and the awake level of the second threshold are identified. Identifying the stimulation operating window further comprises subsequently repeating the step of titrating the stimulation setting of the neurostimulator while the subject is asleep until the asleep level of the second threshold is identified.

Abstract: Monitoring system configured to provide a health chart on an operator display. The health chart includes a plurality of indicators that identify patient parameters. The plurality of indicators form a column that extends parallel to a first axis. The health chart also includes linear projections that are aligned with respective indicators and extend parallel to a second axis that is perpendicular to the first axis. The linear projections represent values of the patient parameters that correspond to the respective indicators. The values are determined by the physiological data obtained from corresponding sensors. The patient monitoring system is configured to determine lengths of the linear projections based on the physiological data. The lengths extend from proximal ends of the linear projections to distal ends of the linear projections. The distal ends move parallel to the second axis toward or away from the respective indicators to change the length.

Abstract: A system and method provides noninvasive mental state diagnostics and brain stimulation via consensual transcranial stimulation. The method utilizes face recognition associated with known physiologic measures to identify an emotional state-of-mind of a human subject and then provides or at least suggests a transcranial stimulation treatment for enhancing mental focus or for alleviating discomfort or anxiety by inducing a feeling of well-being. An example system arrangement utilizes a camera to scan a subject's facial expressions and, if the subject desires, provides a transcranial stimulation to the subject based upon an analysis of the facial expression. In one example environment, the system is used in the office or other workplace. In another example environment, the system is used in conjunction with a vehicle seat, such as for example a seat in a car, train, aircraft or other vehicle.

Abstract: Impedance devices with integrated circuit modules and method of using the same to obtain luminal organ information. In one embodiment, a device comprises an elongated body for at least partial insertion into a mammalian luminal organ and having a first conductor extending therethrough, a proximal electrical unit connected to the elongated body to deliver power along the first conductor, and a sensor substrate located at or near a distal end of the elongated body and comprising a circuit module operable and/or configured to direct the sizing portion to obtain sizing data and the pressure sensor to obtain pressure data, and facilitate transmission of the sizing data and/or the pressure data to the proximal electrical unit.

Abstract: A method for monitoring specific activity parameters of the human heart, where ECG and PCG signal monitoring is performed simultaneously by at least two electrodes placed on the chest in such a way that the ECG signal is utilized as a reference time point during PCG monitoring, and monitoring is performed with a measuring unit consisting of a couple of measuring heads containing combined ECG and PCG electrodes, a controlling master measuring head and a slave measuring head performing synchronized implementation, and a computing evaluating unit which is in wireless data communication connection with the above unit and is capable of data processing. ECG and PCG signals are simultaneously monitored by two measuring heads, each comprising an ECG electrode and a PCG electrode, one of the measuring heads serving as a master measuring head and the other one of the measuring heads serving as a slave measuring head.

Abstract: A method of generating an electrophysiology map of a portion of a patient's anatomy using an electroanatomical mapping system, includes defining a plurality of inclusion criteria, collecting a plurality of electrophysiology data points, each being associated with inclusion data, and identifying those electrophysiology data points that have inclusion data satisfying the inclusion criteria. The inclusion criteria can then be automatically adjusted to drive the number of electrophysiology data points having inclusion data satisfying the inclusion criteria towards a target number. A graphical representation of the electrophysiology map can be rendered using the final set of electrophysiology data points.

Abstract: The present invention relates to a system and a method for improving the security of an operation for writing the memory of an active implantable medical device by long distance telemetry, in particular via network connection with a writing main device. The system and method according to the present invention comprise an intermediate proximity device allowing communication between the active implantable medical device and the main writing device and at least one unlocking tool allowing access to the active implantable medical device.

Abstract: A method and an apparatus for treating a patient suffering from, or at risk for, a condition mediated by the inflammatory cytokine cascade, by electrically stimulating vagus nerve activity in an amount sufficient to inhibit the inflammatory cytokine cascade.

Abstract: Method and systems provide for reliable, convenient, and cost-effective personalized assessment of hemodynamic status in the ambulatory heart failure patient. The method and apparatus use pulse contour analysis of data obtained through observation of the patient for determination of hemodynamic status, and for determination of day-to-day changes in hemodynamic status. Observational assessment of the patient includes monitoring during activities of daily living including sleeping, sitting and standing. These activities create changes in venous return that are used to evaluate cardiac function or changes in cardiac function. The method and system infer body position by using position and motion information obtained by the system. Changes in cardiac function over time or due to changes in body pose are evaluated for the assessment of hemodynamic status, with a focus on changes resulting from fluid overload.

Abstract: Methods and systems are provided for a rate adaptive bi-ventricular fusion pacing. The methods and systems deliver a first pulse at a left ventricular (LV) lead and a second pulse at a right ventricular (RV) lead based on a paced atrio-ventricular (AV) delay. The first pulse timed to be delivered concurrently with an intrinsic ventricular conduction. The methods and systems further repeat the delivery of the first pulse and the second pulse for a predetermined number of cycles. Additionally, the methods and systems measure an intrinsic AV conduction interval, and adjust the paced AV delay based on the intrinsic AV conduction interval and a negative hysteresis delta.