Patents Examined by Nilay Shah
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Patent number: 10080838Abstract: Catheter cannula, catheter, and catheterization method, for administering a fluid or/and substance to, or for draining a fluid or/and substance from, a treatment space of a body vessel, duct, or cavity. In some embodiments the cannula includes: an elongated flexible tube mountable on a needle, and having an invasive section and a non-invasive section; and at least one anchoring element protruding from, a surface of the invasive section in a manner such that an operative configuration of each anchoring element increases outer circumferential diameter of the cannula to an extent less than lumen diameter of the body vessel, duct, or cavity, at the treatment space, thereby anchoring the invasive section to inside the body vessel, duct, or cavity, at the treatment space. The catheter includes a needle and the cannula mounted thereupon.Type: GrantFiled: July 12, 2011Date of Patent: September 25, 2018Assignee: Ramot at Tel-Aviv University Ltd.Inventors: Oren Rotman, Shmuel Einav
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Patent number: 10064674Abstract: According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.Type: GrantFiled: August 21, 2015Date of Patent: September 4, 2018Assignee: Metavention, Inc.Inventors: Bobak Robert Azamian, Scott Bradley Vafai
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Patent number: 10065000Abstract: An assembly for a drug delivery device is provided, the assembly including a blocking element and a piston rod having an interaction feature adapted and arranged to mechanically cooperate with the blocking element. For delivering a dose of a drug, the piston rod is configured to be moved from an initial position to an end position with respect to the blocking element, wherein the interaction feature is provided along the path between the initial position and the end position. An operating noise is provided to the user when the interaction feature mechanically cooperates with the blocking element while moving the piston rod for dose delivery. The interaction feature is adapted for homogenizing the operating noise so as to prevent the operating noise from being interpreted by the user as signalling the end of the dose delivery operation. Furthermore, a drug delivery device is provided.Type: GrantFiled: April 17, 2013Date of Patent: September 4, 2018Assignee: Sanofi-Aventis Deutschland GMBHInventors: Michael Helmer, Christian Dexheimer, Winfried Huthmacher, Christoph Eissengarthen, Carsten Mosebach
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Patent number: 10058658Abstract: A sealing article for use with a fluid conveyance device comprises an elastomeric body including a first end defining a disk-shaped annular protrusion, and an annular recess formed in a sidewall thereof directly adjacent the first end of the body in an axial direction of the body. The recess is sized to receive at least a portion of the annular protrusion in response to the sealing article being inserted into an interior cavity of the fluid conveyance device. A barrier material is attached to or formed on a first end of the body and extends over the radial protrusion.Type: GrantFiled: May 26, 2017Date of Patent: August 28, 2018Assignee: PRECISION POLYMER PRODUCTS, INC.Inventor: Joseph M. Voytilla
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Patent number: 10046152Abstract: An operation tool for a fluid injector includes a selective movement mechanism which moves the fluid injector between a first protruding position and a second protruding position in a housing of an outer cylinder. When the fluid injector is at the first protruding position, microneedles of a multi-microneedle device are protruded out to a first distance from the first open end. When the fluid injector is at the second protruding position to discharge a fluid via the microneedles, the microneedles are protruded out to a second distance from the first open end, which is shorter than the first distance. The selective movement mechanism includes a rotational-linear movement conversion mechanism which moves the fluid injector between the first and second protruding positions along a longitudinal center line of the outer cylinder based on a direction and an amount of rotation of the outer cylinder relative to the fluid injector.Type: GrantFiled: April 17, 2015Date of Patent: August 14, 2018Assignee: TOPPAN PRINTING CO., LTD.Inventors: Tomoya Sumida, Yumiko Ikeda, Masaki Kono, Yoshihiro Kodama, Kazuhiko Shiomitsu
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Patent number: 10022497Abstract: A system allows for collection and re-use of a fluid medium derived from diverting at least some of the fluid medium of an injection. The system comprises a sterile container, an injector, a delivery catheter, a flow diverter assembly and a diversion reservoir assembly. The delivery catheter is in communication with a selected site within a patient's body. The flow diverter assembly is disposed in a flow path between the injector and the delivery catheter and is configured to divert at least a portion of a medium of the injection from the flow path. The diversion reservoir assembly has a reservoir chamber fluidly coupled to the flow diverter assembly. The reservoir chamber is configured to receive the diverted portion of the fluid medium to allow re-use by the medium injector of the diverted portion.Type: GrantFiled: September 11, 2015Date of Patent: July 17, 2018Assignee: Osprey Medical, Inc.Inventors: William Burmaster, Tuan M. Doan, Rodney L. Houfburg
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Patent number: 10016341Abstract: Systems and devices for controlling delivery of a breast milk supplement are described which include a nipple component including aperture; a guard component attached to the nipple component; a supplement reservoir including a port with a controllable valve, the supplement reservoir adapted to contain one or more breast milk supplements, a flow conduit disposed within at least a portion of the nipple component and having a first end in fluid communication with the aperture and a second end in fluid communication with the port; a data storage component including a breast milk supplement regimen; and a control unit operably coupled to the controllable valve and the data storage component and including a microprocessor and circuitry, the circuitry including actuation circuitry configured to actuate the controllable valve to module release of the one or more breast milk supplements based on the breast milk supplement regimen.Type: GrantFiled: March 30, 2015Date of Patent: July 10, 2018Assignee: Elwha LLCInventors: Hon Wah Chin, Roderick A. Hyde, Elizabeth A. Sweeney, Lowell L. Wood, Jr.
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Patent number: 10010683Abstract: Described is an autoinjector comprising a case, a drive carriage disposed in the case, and a plunger coupled to the drive carriage. The plunger is adapted to releasably engage a needle retraction mechanism in a syringe. Translation of the drive carriage in a distal direction relative to the case causes the plunger to engage the needle retraction mechanism and translation of the drive carriage in a proximal direction relative to the casing case the plunger to needle retraction mechanism the stopper.Type: GrantFiled: April 20, 2016Date of Patent: July 3, 2018Assignee: Sanofi-Aventis Deutschland GMBHInventors: Thomas Henley, David Cross, Douglas Ivan Jennings, Ryan Anthony McGinley
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Patent number: 10010673Abstract: A system for modulating delivery of a fluid medium to a selected site within a patient's body includes a syringe for injecting the fluid medium, a delivery catheter including a conduit for delivering the fluid medium from outside of the body to the selected site within the body, a medium reservoir configured to receive a portion of the fluid medium, and a flow diverter assembly disposed in a fluid medium flow path between the syringe and the delivery catheter. The syringe includes a chamber for receiving the fluid medium therein. The flow diverter assembly is configured to divert the portion of the fluid medium from the chamber of the syringe away from the delivery of the medium through the delivery catheter conduit during injecting with the syringe, and simultaneously increase medium fluid flow resistance with increasing pressure level of the fluid medium within the flow diverter assembly.Type: GrantFiled: September 11, 2015Date of Patent: July 3, 2018Assignee: Osprey Medical, Inc.Inventors: Matthew M. Burns, Tuan M. Doan, Rodney L. Houfburg, David M. Kaye, Todd J. Mortier
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Patent number: 10004849Abstract: The invention inter alia relates to a dispense interface for an ejection device. The dispense interface comprises at least two inlets, at least one outlet and a part having multiple portions; wherein the multiple portions are connected by living hinges such that the multiple portions are foldable towards each other; wherein the multiple portions are configured to form a fluid channel arrangement between functional surfaces of the multiple portions facing each other when the multiple portions are folded towards each other; wherein at least two functional surfaces of the functional surfaces are inclined to each other when the multiple portions are folded towards each other; and wherein the fluid channel arrangement is configured to provide fluid communication between the at least two inlets and the at least one outlet.Type: GrantFiled: May 16, 2013Date of Patent: June 26, 2018Assignee: Sanofi-Aventis Deutschland GmbHInventors: Frederic Laugere, Cristian Popa, Ben Impey, Andrew MacLeod
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Patent number: 9999718Abstract: An apparatus includes a syringe housing and a plunger slidably received within the syringe housing between a first position and a second position. The plunger has a substantially opaque portion and a substantially translucent portion. A light sensor module is disposed on the syringe housing. The light sensor module has a light sensor housing and a first sensor element and a second sensor element. The first sensor element and the second sensor element are disposed within the sensor housing. Positioning the plunger at the first position aligns the substantially translucent portion with the first sensor element and positioning the plunger at the second position aligns the substantially translucent portion with the second sensor element.Type: GrantFiled: March 21, 2014Date of Patent: June 19, 2018Assignee: OSPREY MEDICAL, INC.Inventors: Dale Brady, Dustin Kasel, Rodney L. Houfburg
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Patent number: 9999412Abstract: A fistula management device for preventing enteric contents from leaking out of a bowel via a fistula opening in the bowel. The device comprises a tubular body that defines a main fluidic passageway extending from a first axial end to a second axial end of the tubular body. Inflatable cuffs are located at each of the first and second axial ends of the tubular body for creating a fluid seal between the first and second axial ends of the tubular body and inner walls of a bowel.Type: GrantFiled: February 7, 2013Date of Patent: June 19, 2018Assignee: The Regents of the University of MichiganInventor: Barbra Miller
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Patent number: 9987428Abstract: An injector (100) may include a container (102) having a wall (110) with an interior surface (112) and a seal assembly (140) with an interior surface (142), the interior surfaces (110) of the wall (110) and the seal assembly (140) defining a closed sterile reservoir (150) filled with a drug product. The injector (100) may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle (180) having a point (182) disposed only partially through the seal assembly (140) in a storage state, and disposed through the interior surface (142) of the seal assembly (140) into the sterile reservoir (150) in a delivery state. Further, the injection may include an actuator (106) that is adapted to move the container needle from the storage state to the delivery state.Type: GrantFiled: October 11, 2012Date of Patent: June 5, 2018Assignee: AMGEN INC.Inventors: Francisca Tan-Malecki, Ronald Forster, Scott M. Nunn, Mark D. Holt, Son C. Tran, Sheldon Moberg
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Patent number: 9987438Abstract: A tamper resistant/evident cap cover for IV needle configurations to provide a single use engageable cap to prevent unauthorized access and use of an IV needle port. The cap cover has a threaded IV needle receiving base and a slidably disposed interengagement locking clasp. Oppositely disposed tamper evident latching tabs are receivably secured into the base by multiple clasp barbs defining a first position for access and a second closed locked position.Type: GrantFiled: May 29, 2014Date of Patent: June 5, 2018Inventor: Randall Stillson
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Patent number: 9962492Abstract: A syringe assembly having a barrel for containing one or more medicaments and a stopper disposed in the barrel defining and separating a first volume and a second volume within the syringe assembly. The stopper includes a permanent seal fluidly sealing the stopper to the barrel about the entire perimeter of the stopper intermediate the first volume and second volume, and a channel bypassing the permanent seal, the channel having a first opening in fluid communication with the second volume and a second opening selectively sealed from the first volume by a resilient seal. The resilient seal is moveable between a sealing configuration and an open configuration to selectively seal the channel from the first volume and is moveable from the sealing configuration to the open configuration upon fluid pressure in the first volume or second volume exceeding a first pressure threshold.Type: GrantFiled: February 22, 2013Date of Patent: May 8, 2018Assignee: CONSORT MEDICAL PLCInventors: Ian Anderson, Matt Ekman
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Patent number: 9950111Abstract: A device for the transcutaneous, in vivo measurement of the concentration of at least one analyte in a living organism includes a catheter which can be introduced into the organism, and a luminescence indicator, which is immobilized on the catheter and which reacts to a change in the concentration of the at least one analyte to be measured with a change in at least one optical property. The luminescence indicator is transcutaneously connected to a source for providing an excitation radiation and a detector for detecting the measuring radiation. The luminescence indicator is immobilized on the outer circumference of the catheter, which is used to dispense a fluid medium, for example a medication, into the organism or to drain a body fluid.Type: GrantFiled: June 2, 2010Date of Patent: April 24, 2018Assignees: JOANNEUM RESEARCH FORSCHUNGSGESELLSCHAFT MBH, TECHNISCHE UNIVERSITÄT GRAZInventors: Hans Köhler, Ingo Klimant
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Patent number: 9949777Abstract: A method for the long-term delivery of fluids to a bone of a patient includes providing a cannulated bone screw and an insert configured to be coupled to the bone screw. The method further includes creating an aperture in the skin of a patient, inserting the bone screw into a bone of the patient through the aperture, and coupling the insert to the bone screw. The method further includes the steps of providing a fluid source, coupling the fluid source to the insert, and delivering a fluid from the fluid source to the insert.Type: GrantFiled: May 3, 2013Date of Patent: April 24, 2018Assignee: Spinal Generations, LLCInventor: Patrick J. Sweeney
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Patent number: 9950126Abstract: A medication injector that has an alert indicator that alerts the user when the medication injector is approaching near the end of its medication supply is disclosed. The alert indicator gives the user an opportunity to make preparations to obtain additional medication for the injector if there is an insufficient amount of medication in the injector to enable the user to dispense the required dosage amount with the next injection. Initially, the alert indicator is not visible to the user, but becomes visible to the user when the injector is near empty.Type: GrantFiled: December 5, 2013Date of Patent: April 24, 2018Assignee: Merck Sharp & Dohme Corp.Inventors: Peter A. Basile, Jeffrey C. Givand, Steven Carl Persak
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Patent number: 9931467Abstract: An autoinjector includes a body (1; 1010), a reservoir containing fluid product, a piston, a needle, a piston rod (5 5; 1005) that is displaceable between a loaded position and an injection position, and an injection spring (8; 1008) to stress 10 the piston rod towards the injection position. The autoinjector also includes an injection lock having a control sleeve (4; 1004) containing the piston rod and the injection spring. The piston rod includes a radial recess (50; 1050) receiving a substantially spherical blocking element (7; 1007) mobile between a blocking position and an unblocking position, stressed radially towards the exterior by the piston rod, and held in the blocking position by a blocking member (23; 1004) that is displaceable relative to the piston rod to release the blocking element.Type: GrantFiled: May 24, 2013Date of Patent: April 3, 2018Assignee: APTAR FRANCE SASInventors: David Fabien, Antoine Mansencal, Matthieu Walter
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Patent number: 9919111Abstract: Penetrating systems and devices are described herein which include a penetrating portion having a fluid reservoir portion formed from two concentric hollow cylinders joined at one end with a substantially ring-shaped first end piece and associated at the other end with a substantially ring-shaped second end piece, the outer hollow cylinder including a plurality of pores in fluid communication with the fluid reservoir portion, the inner hollow cylinder defining a lumen in fluid communication with a second fluid reservoir portion, and the substantially ring-shaped second end piece forming a deformable barrier.Type: GrantFiled: June 30, 2014Date of Patent: March 20, 2018Assignee: Elwha LLCInventors: Roderick A. Hyde, Muriel Y. Ishikawa, Nathan P. Myhrvold, Elizabeth A. Sweeney, Lowell L. Wood, Jr.