Abstract: A method for determining anatomical dead space in a respiratory tract of a living organizm, include the steps of continuously and simultaneously measuring flow (F) and respiratory air density (D) during exhalation (EX) over time (T). The time is measured from the start of exhalation, in which the flow is greater than zero, until the dead space point at which, after significant decreases following the start, the respiratory air density merges to an approximately constant value. The integral of the flow is formed from the start point until the dead space end point, the measurements of the respiratory air density and the flow from the start until the dead space end point and during the short time, as that time span in which the respiratory air density assumes an approximately constant value, taken place multiple times in each case.

Abstract: A blood pressure monitor includes a cuff to be wound around a living body of a subject, a measuring unit for measuring blood pressure with said cuff wound around the living body of said subject, a detecting unit for detecting an inclination angle of said cuff, a specifying unit for specifying a current inclination level among a plurality of predetermined inclination levels upon measurement by said measuring unit, based on a result of detection by said detecting unit, a memory for storing therein the inclination level specified by said specifying unit, in association with blood pressure data measured by said measuring unit, and a notifying unit for providing notification of at least one past inclination level of the plurality of inclination levels stored in said memory and said current inclination level, in association with each other.

Abstract: An optical sensor for a monitoring device for monitoring the vital signs of a user is disclosed herein. The optical sensor preferably includes a photodetector and a two light emitting diodes (“LEDs”) that emit green light. The optical sensor includes a light barrier that includes multiple walls that block any non-reflected light from the LEDs from transmission to the photodetector so that the photodetector only receives light reflected from the artery of the user resulting in a more accurate detection of the heart rate of the user. A sensor signal from the optical sensor is processed with an accelerometer output signal from the accelerometer to generate a real-time vital sign for a user.

Abstract: A handheld, conforming capacitive sensing apparatus configured to measure Sub-Epidermal Moisture (SEM) as a mean to detect and monitor the formation of pressure ulcers. The device incorporates an array of electrodes which are excited to measure and scan SEM in a programmable and multiplexed manner by a battery-less RF-powered chip. The scanning operation is initiated by an interrogator which excites a coil embedded in the apparatus and provides the needed energy burst to support the scanning/reading operation. Each electrode measures the equivalent sub-epidermal capacitance corresponding and representing the moisture content.

Abstract: A method for operating measuring equipment for detecting an analyte in a bodily fluid by means of a continuously measuring blood glucose sensor. A calibration method is carried out for the prospective calibration of the measuring equipment. At least three calibration points are detected in the calibration method, wherein each calibration point comprises a measurement signal from the measuring equipment and a reference value of an associated reference measurement. A plurality of possible slopes are established between the calibration points. At least one robust estimation method using a formation of at least one median is used to determine a probable slope from the plurality of possible slopes. Furthermore, a measurement is carried out. During the measurement and using the probable slope, a concentration of the analyte in the bodily fluid is deduced from a measurement signal from the measuring equipment and the probable slope.

Abstract: Diagnostic classifications of pulse signal waveform data is provided. In one example, diagnosis or prediction of a disease may be performed by analyzing pulse signal waveform data, and comparing aspects of the pulse signal waveform data with a morphology pattern that has been found to indicate a subject is suffering from a specific disease. A pulse signal can be captured via wrist electrodes using bio-electric sensors based on an impedance plethysmographic principle, for example, and processed using feature extraction for diagnosis and assessment of the subject's proneness to a disease. Analysis of the pulse signal and pulse morphology patterns provides an in-vitro, non-invasive, and low-cost method for diagnosing diseases.

Abstract: The invention relates to a device for implementing a system for detecting the observance by a patient of an oxygen-therapy treatment involving an oxygen supply, and for recording the data of said treatment and transmitting said data. The invention also relates to the use of said device, and to a method for tracking the observance of an oxygen-therapy treatment.

Abstract: A disposable active pulse sensor has an emitter that generates optical radiation having a plurality of wavelengths, a detector that is responsive to the optical radiation and an unbalanced electrical motor that vibrates when energized. A tape assembly removably attaches the emitter, the detector and the unbalanced electrical motor to a tissue site. The tape assembly also physically mounts the emitter, the detector and the unbalanced electrical motor in a spatial arrangement so that vibration from the unbalanced electrical motor induces pulsatile blood flow within the tissue site, the emitter transmits the optical radiation into the tissue site and the detector generates a sensor signal responsive to the intensity of the optical radiation after attenuation by the pulsatile blood flow within the tissue site.

Abstract: A respiration sensing subsystem includes a band made of stretchable material and a pair of spaced conductors extending along the band in a flexible pattern. A moisture repellant compound is added to the stretchable material of the band between the pair of spaced conductors.

Abstract: Devices and methods useful for sensing or measuring a pressure and remotely indicating or communicating that pressure are provided. The devices and methods have particular utility in sensing pressures in implantable medical devices and more particularly in hydrocephalus shunts. In one exemplary embodiment, an implantable valve can include a housing having a reservoir adapted to receive fluid flow therethrough between an inlet port and an outlet port. The implantable valve can also include a needle-penetrable septum to allow fluid delivery to the reservoir and/or a needle guard disposed within the housing and adapted to protect the radio frequency tag from a needle penetrating into the housing. A radio frequency (RF) tag can be disposed within the reservoir and can be adapted to change one or more of its electromagnetic characteristics in response pressure applied thereto by fluid in or flowing through the reservoir.

Abstract: An intravascular sensor delivery device for measuring a physiological parameter of a patient, such as blood pressure, within a vascular structure or passage. In some embodiments, the device can be used to measure the pressure gradient across a stenotic lesion or heart valve. For example, such a device may be used to measure fractional flow reserve (FFR) across a stenotic lesion in order to assess the severity of the lesion. The sensor delivery device has a distal sleeve configured to pass or slide over a standard medical guidewire. Some distance back from the sensor and distal sleeve, the device separates from the guidewire to permit independent control of the sensor delivery device and the guidewire. The sensor delivery device can be sized to pass over different sizes of guidewires to enable usage in coronary and peripheral arteries, for example.

Abstract: Automated seizure detection from within an electroencephalogram (EEG) by instrumental means employs novel algorithms within software, using specific measurements of individual waves in trains, rather than any “bulk” process. The acquired signal is filtered, the wave shapes are individually described within a number of parallel runs using a variety of parameters, then criteria (including regularity criteria) are calculated and applied in order to create raw detection results. Finally the raw results are “integrated” for display. As a result, reported seizures closely follow the incidence and duration of seizures detected by trained clinicians. The invention is useful in intensive-care monitoring of EEGs from neonates and in EEG monitoring in general.

Abstract: A mountable device includes a bio-compatible structure embedded in a polymer that defines at least one mounting surface. The bio-compatible structure has a first side defined by a first layer of bio-compatible material, a second side defined by a second layer of bio-compatible material, an electronic component, and a conductive pattern that defines sensor electrodes. A portion of the second layer of bio-compatible material is removed by etching to create at least one opening in the second side in which the sensor electrodes are exposed. The etching further removes a portion of the first layer of bio-compatible material so as to create at least one opening in the first side that is connected to the at least opening in the second side. With this arrangement of openings, analytes can reach the sensor electrodes from either the first side or the second side of the bio-compatible structure.

Abstract: In specific embodiments, a method for estimating central arterial blood pressure (CBP), comprises determining a time t1 from a predetermined feature of a signal indicative of electrical activity to a predetermined feature of one of a first and second signals, the time t1 being a first pulse arrival time (PAT1) indicative of how long it takes a pulse wave to travel from the aorta to one of a first and second sites, determining a time t2, the time t2 being a second pulse arrival time (PAT2) indicative of how long it takes a pulse wave to travel from the aorta to the other of the first and second sites, and (f) estimating the patient's central arterial blood pressure (CBP) based on the first pulse arrival time (PAT1) and the second pulse arrival time (PAT2).

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous and subcutaneous measurement of glucose in a host.

Abstract: The present invention is directed to membranes composed liquid crystals having continuous aqueous channels, such as a lyotropic liquid crystal, including a cubic phase lyotropic liquid crystal, and to electrochemical sensors equipped with such membranes. The membranes are useful in limiting the diffusion of an analyte to a working electrode in an electrochemical sensor so that the sensor does not saturate and/or remains linearly responsive over a large range of analyte concentrations. Electrochemical sensors equipped with membranes of the present invention demonstrate considerable sensitivity and stability, and a large signal-to-noise ratio, in a variety of conditions.

Abstract: In a sphygmomanometer for measuring blood pressure according to a volume compensation method, an upper arm V0 equivalent cuff pressure representing a cuff pressure in a state where an inner pressure and an outer pressure of an artery of an upper arm are in equilibrium is specified based on a cuff pressure signal of the upper arm. For example, the upper arm V0 equivalent cuff pressure is detected as an average blood pressure obtained from the cuff pressure signal of the upper arm. After a control target value and an initial cuff pressure in the volume compensation are detected, a difference between the initial cuff pressure and the upper arm V0 equivalent cuff pressure is calculated as a correction value, and the blood pressure value in the volume compensation method is corrected with the calculated correction value.

Abstract: An adjustment device for a hearing aid includes: an audio extraction section for, through an acoustic process of a collected audio signal, utilizing information of a phoneme or syllable contained in the audio signal to output time information, the time information identifying a point of uttering the phoneme or syllable; an electroencephalogram measurement section for measuring an electroencephalogram signal of a user; a determination section for determining a difficulty of hearing of the phoneme or syllable by relying on an event-related potential in the electroencephalogram signal based on the identified point of uttering the phoneme or syllable as a starting point; a phoneme identification section for, when a plurality of phonemes or syllables are determined as difficult to hear, identifying a chronologically preceding phoneme or syllable among them to be difficult to hear; and a gain adjustment section for, with respect to the phoneme or syllable identified by the phoneme identification section, determinin

Abstract: An apparatus and a method of analyzing constituents of gas in an oral cavity and exhaled breath is disclosed. The apparatus for analyzing the constituents of gas in the oral cavity and exhaled breath according to the present invention includes a filter to filter the outside gas by adsorbing polar molecules and non-polar molecules in the outside air and by removing water in the outside air in order to use the outside gas as carrier gas. The apparatus can also include a plurality of solenoid valves for controlling the flow of a carrier gas; a sensor for detecting components of the exhaled breath; a pump to draw the gas in the oral cavity or the exhaled breath and the carrier gas and discharge the gases to the outside; a control unit for controlling the components of the apparatus; and a display device to display results calculated by the control unit.

Abstract: An acoustic means for rendering key respiratory measurements accessible to hand-held mobile digital devices with audio input capabilities (such as mobile phones, personal digital assistants, mobile gaming platforms, and tablets). One or more embodiments comprise: a compact and portable whistle (101) that encodes a user's expiratory airflow rate as audio frequency, and a software process with local or remote access to mobile-device audio that decodes said audio frequency to regain expiratory airflow rate and derive key respiratory measurements, so that these measurements and related information may conveniently be made available to the user (100) and the user's health network of family members (103) and physicians (104). Embodiments enable leveraging the ubiquity and extensive capabilities of hand-held mobile digital devices, while simultaneously simplifying requirements for a dedicated spirometry device.