Patents Examined by Patricia Mallari
-
Patent number: 9131855Abstract: The present invention provides an apparatus and methods for continuous intravascular measurement of whole blood concentration, blood pressure, and pulse pressure. The intravascular catheter incorporates a sensor to measure whole blood sound velocity, attenuation, backscatter amplitude, and blood flow velocity and also incorporates existing technologies for multiple physiologic measurements of whole blood. Pulse wave velocity and wave intensity are derived mathematically for purposes of estimating degree of local vascular tone.Type: GrantFiled: July 13, 2009Date of Patent: September 15, 2015Assignee: New Paradigm Concepts, LLC.Inventor: Edwin L. McEowen
-
Patent number: 9131885Abstract: Analyte sensors and methods of manufacturing same are provided, including analyte sensors comprising multi-axis flexibility. For example, a multi-electrode sensor system 800 comprising two working electrodes and at least one reference/counter electrode is provided. The sensor system 800 comprises first and second elongated bodies E1, E2, each formed of a conductive core or of a core with a conductive layer deposited thereon, insulating layer 810 that separates the conductive layer 820 from the elongated body, a membrane layer deposited on top of the elongated bodies E1, E2, and working electrodes 802?, 802? formed by removing portions of the conductive layer 820 and the insulating layer 810, thereby exposing electroactive surface of the elongated bodies E1, E2.Type: GrantFiled: July 1, 2010Date of Patent: September 15, 2015Assignee: DexCom, Inc.Inventors: Peter C. Simpson, Robert Boock, Paul V. Neale, Sebastian Bohm, Matthew Wightlin, Jack Pryor, Jason Mitchell, Jeff Jackson, Kaushik Patel, Antonio C. Llevares
-
Patent number: 9119535Abstract: A blood pressure measurement device accurately calculates an index useful in determining the degree of arteriosclerosis by accurately detecting a difference in time of appearance of a ejection wave and reflected wave in a blood pressure waveform. The device sets a threshold value based on an index that expresses a characteristic of the blood pressure waveform with respect to the point of appearance of the reflected wave in the blood pressure and estimates a rise point of the reflected wave by calculating an x-coordinate value of a point based on a maximum amplitude of the reflected wave and the threshold value. The device obtains the index of degree of arteriosclerosis by calculating a time difference in appearance between the ejection wave and the reflected wave based on the estimated rise point of the reflected wave.Type: GrantFiled: December 8, 2011Date of Patent: September 1, 2015Assignee: OMRON HEALTHCARE Co., Ltd.Inventors: Kenji Fujii, Tatsuya Kobayashi, Toshihiko Ogura
-
Patent number: 9113789Abstract: Techniques are provided for estimating electrical conduction delays with the heart of a patient based on measured immittance values. In one example, impedance or admittance values are measured within the heart of a patient by a pacemaker or other implantable medical device, then used by the device to estimate cardiac electrical conduction delays. A first set of predetermined conversion factors may be used to convert the measured immittance values into conduction delay values. In some examples, the device then uses the estimated conduction delay values to estimate LAP or other cardiac pressure values. A second set of predetermined conversion factors may be used to convert the estimated conduction delays into pressure values. Techniques are also described for adaptively adjusting pacing parameters based on estimated LAP.Type: GrantFiled: May 31, 2012Date of Patent: August 25, 2015Assignee: Pacesetter, Inc.Inventors: Brian Jeffrey Wenzel, Dorin Panescu, Mihir Naware, Jeffery Siou
-
Patent number: 9113791Abstract: Measured blood pressure data is stored in a memory in association with information related to a measurement time. In response to manipulation of a manipulation portion (memory recall switch), blood pressure data associated with the measurement time within a prescribed time period (for example, 10 minutes) from the measurement time of reference blood pressure data, among the blood pressure data stored in the memory, is retrieved as specific data. Then, an average value is calculated based on the specific data, and the calculated average value is displayed as an evaluation index.Type: GrantFiled: August 10, 2006Date of Patent: August 25, 2015Assignee: OMRON HEALTHCARE Co., Ltd.Inventors: Hiroshi Kishimoto, Yukiya Sawanoi, Takahide Tanaka, Kenji Eda
-
Patent number: 9113829Abstract: A mountable device includes a bio-compatible structure embedded in a polymer that defines at least one mounting surface. The bio-compatible structure includes an electronic component having electrical contacts, sensor electrodes, and electrical interconnects between the sensor electrodes and the electrical contacts. The bio-compatible structure is fabricated such that it is fully encapsulated by a bio-compatible material, except for the sensor electrodes. In the fabrication, the electronic component is positioned on a first layer of bio-compatible material and a second layer of bio-compatible material is formed over the first layer of bio-compatible material and the electronic component. The electrical contacts are exposed by removing a portion of the second layer, a conductive pattern is formed to define the sensor electrodes and electrical interconnects, and a third layer of bio-compatible material is formed over the conductive pattern.Type: GrantFiled: March 27, 2013Date of Patent: August 25, 2015Assignee: Google Inc.Inventor: James Etzkorn
-
Patent number: 9103816Abstract: The present invention is to present a blood sample analyzing apparatus, comprising: an aspirator for aspirating a blood sample to be used for measurement; a coagulation determiner for determining whether the blood sample is coagulated or not; and an aspirating controller for controlling an operation of the aspirator based on a determination result by the coagulation determiner.Type: GrantFiled: July 21, 2009Date of Patent: August 11, 2015Assignee: Sysmex CorporationInventors: Tokihiro Kosaka, Koichi Okubo
-
Patent number: 9101302Abstract: An analyte test device is constructed as an integrated, single-use, disposable cartridge which can be releasably installed into a compatible analyte test monitor. In use, the device can be used in conjunction with the monitor to lance the skin of a patient to create a blood sample, express the blood sample from the wound site using vacuum forces and calculate the concentration of a particular analyte in the expressed blood sample. In one embodiment, the device includes a base which includes a top surface and a bottom surface. The base is also shaped to define an aperture which extends transversely through its top and bottom surfaces. An electrochemical test sensor is affixed to the base in such a manner so that a vacuum path is at least partially defined between the base and the test sensor, the vacuum path being in fluid communication with the aperture.Type: GrantFiled: May 3, 2004Date of Patent: August 11, 2015Assignee: Abbott Diabetes Care Inc.Inventors: Chad Harold Mace, Paul Sen Yang, Farzad Shahrokni
-
Patent number: 9095307Abstract: A sleep apnea diagnostic system includes a housing that is configured to be attached to near the nose of a patient's face to sense physiological information of a patient. The housing includes sensors to sense the physiological information. The physiological information may be, for example, air flow through the nose or the mouth or both. The physiological information further may be, for example, blood volume. The sleep apnea diagnostic system includes at least one processor in the housing or external to the housing or both to analyze the physiological information to determine whether the patient has experienced irregular or abnormal respiratory activity and to detect respiratory effort. The analysis may be real time or delayed.Type: GrantFiled: March 14, 2014Date of Patent: August 4, 2015Assignee: Somnarus Inc.Inventors: Maria A. Parfenova, Alexandr S. Parfenov, Yuri P. Zobnin
-
Patent number: 9066660Abstract: According to embodiments, systems and methods for high-pass filtering a plethysmograph or photoplethysmograph (PPG) signal are disclosed. A sensor or probe may be used to obtain a plethysmograph or PPG signal from a subject. The sensor may be placed at any suitable location on the body, e.g., the forehead, finger, or toe. The PPG signal generated by the sensor may be high-pass filtered to disambiguate certain features of the PPG signal, including one or more characteristic points. The cut-off frequency for the high-pass filter may be greater than 0.75 Hz and less than 15 Hz. The cut-off frequency for the high-pass filter may be selected to be greater than the subject's computed pulse rate. These characteristic points on the filtered PPG signal may be used to compute non-invasive blood pressure measurements continuously or on a periodic basis. For example, the time difference between two or more characteristic points in a high-pass filtered version of the generated PPG signal may be computed.Type: GrantFiled: September 29, 2009Date of Patent: June 30, 2015Assignee: Nellcor Puritan Bennett IrelandInventors: James N. Watson, Paul Stanley Addison
-
Patent number: 9066696Abstract: The present invention provides a sensor insertion and removing device which is user-friendly and which does not cause infection. The sensor insertion and removing device has a sensor; a puncture blade member; a housing which houses the sensor and the puncture blade member; a guide part which is provided within the housing and which glidably supports the puncture blade member; a puncture blade operating part which inserts the sensor under the skin by causing the puncture blade member to glide along the guide part integrally with the sensor, upon delivering the puncture blade member outside the housing to puncture the skin, and which causes the puncture blade member to glide along the guide part in a state of being separated from the sensor, upon removing the puncture blade member from under the skin into the housing, and a sensor operating part which pulls out the sensor from under the skin and removes it from under the skin into the housing.Type: GrantFiled: August 30, 2011Date of Patent: June 30, 2015Assignee: ARKRAY, Inc.Inventors: Tomohiro Shoshihara, Yosuke Murase, Akihiro Yamamoto
-
Patent number: 9022946Abstract: A sensor assembly includes a sensing element and an actuator. The sensing element measures a parameter associated with gas in an airway. The actuator actuates the sensing element to prevent contamination build up on the sensing element.Type: GrantFiled: May 20, 2010Date of Patent: May 5, 2015Assignee: CareFusion 207, Inc.Inventor: Kamran Haque
-
Patent number: 9022945Abstract: Implantable systems, and methods for use therewith, are provided for monitoring for an impending myocardial infarction. A signal indicative of changes in arterial blood volume is obtained. Such a signal can be a photoplethysmography signal or an impedance plethysmography signal. For each of a plurality of periods of time, a metric indicative of the areas under the curve of the signal or number of inflections in the signal is determined. An impending myocardial infarction is monitored for based on changes in the metric indicative of the area under the curve of the signal or number of inflections in the signal, and an alert and/or therapy is triggered in response to an impending myocardial infarction being predicted.Type: GrantFiled: February 4, 2014Date of Patent: May 5, 2015Assignee: Pacesetter, Inc.Inventors: Timothy A. Fayram, Daniell Dokko, Taraneh Ghaffari Farazi, Mark Carlson
-
Patent number: 9011347Abstract: One or more respiratory characteristics of a patient are measured by coupling patient monitor apparatus (e.g., a photoplethysmograph (“PPG”)) to the patient in order to produce a patient monitor signal that includes signal indicia indicative of effort the patient is exerting to breathe. A breathing or respiratory effort signal for the patient is extracted from the patient monitor signal. A respiratory characteristic signal is extracted (at least in part) from the effort signal. This may be done, for example, on the basis of an amplitude feature of the effort signal and a relative time of occurrence of that amplitude feature. Alternatively, the respiratory characteristic signal may be based on a relationship between two amplitude features of the effort signal, with or without regard for specifics of the times of occurrence of those amplitude features. A breath air flow meter may also be coupled to the patient, if desired, in order to produce a flow signal.Type: GrantFiled: July 2, 2009Date of Patent: April 21, 2015Assignee: Nellcor Puritan Bennett IrelandInventors: Paul Stanley Addison, Andrew M. Cassidy, James N. Watson
-
Patent number: 9011342Abstract: An intravascular sensor delivery device for measuring a physiological parameter of a patient, such as blood pressure, within a vascular structure or passage. In some embodiments, the device can be used to measure the pressure gradient across a stenotic lesion or heart valve, such as a fractional flow reserve (FFR) across a stenotic lesion. The sensor delivery device has a distal sleeve configured to pass or slide over a standard medical guidewire. The sensor delivery device can be sized to pass over different sizes of guidewires to enable usage in coronary and peripheral arteries, for example. The sensing mechanism (sensor) can be a fiber optic pressure sensor, such as a MEMS-based FabryPerot fiber optic pressure sensor, for example, or could employ some other technology, e.g., MEMS capacitive or piezoresistive sensor.Type: GrantFiled: March 13, 2012Date of Patent: April 21, 2015Assignee: ACIST Medical Systems, Inc.Inventors: Dale R. Manstrom, Amy R. Raatikka, Robert F. Wilson, Edward R. Miller, Jung Kwon Pak
-
Patent number: 9005131Abstract: Disclosed is a system and method for monitoring the breath chemistry of a patient's breath using a specially designed self-condensing sensor module mounted in a mask, nasal cannula, headband with boom apparatus, or similar device for directing the patients' breath towards the self-condensing sensor. Monitoring of a patient's breath pH provided by the miniaturized self-condensing pH sensor provides for real-time monitoring of patient airway pH values. The specially designed self-condensing sensor module incorporates a data transfer means, e.g. direct wiring or by providing a transmitter with an antenna for wireless transferring of the pH data to a processing receiver. The self-condensing pH sensor comprises a multi-tubular design with the outer tubular member housing a silver chloride reference element, an ion conducting path, and an antimony sensor plug isolated in an inner tubular member that is co-linearly or coaxially configured with the outer tubular member.Type: GrantFiled: October 10, 2006Date of Patent: April 14, 2015Inventors: Ross Tsukashima, Jeffery D. Schipper, Leo R. Roucher, Jr., Erich H. Wolf, Charles S. Bankert
-
Patent number: 8998818Abstract: A system for detecting and measuring increased global or local intracranial pressure includes various devices for performing controlled occlusion of jugular cranial blood outflow and generating occlusion data related to said controlled occlusion, a cranial blood outflow pressure measurement device and a processor for processing jugular cranial blood outflow occlusion data and cranial blood outflow data to identify and/or measure a functional relationship between the jugular controlled occlusion and the jugular cranial blood outflow pressure. A device communicates the functional relationship a display device and/or a patient monitoring system. The processor also detects a state of equilibrium between the jugular cranial blood outflow pressure and the jugular occlusion pressure at occlusion.Type: GrantFiled: February 6, 2012Date of Patent: April 7, 2015Inventors: Henrikas Pranevicius, Mindaugas Pranevicius, Osvaldas Pranevicius, David Liebeskind
-
Patent number: 8974387Abstract: Various embodiments are described and illustrated to calculate an insulin bolus, recommend such bolus, and provide reminder messages for performing an additional glucose test.Type: GrantFiled: June 30, 2010Date of Patent: March 10, 2015Assignee: LifeScan Scotland LimitedInventors: Ian Shadforth, David Price, Gretchen Anderson, Lorraine Comstock, Mary McEvoy, Douglas Graham, Alexander Strachan, Alistair Longmuir, Robert Cavaye, Gillian Teft
-
Patent number: 8971980Abstract: An analyte test device is constructed as an integrated, single-use, disposable cartridge which can be releasably installed into a compatible analyte test monitor. In use, the device can be used in conjunction with the monitor to lance the skin of a patient to create a blood sample and, in turn, calculate the concentration of a particular analyte in the expressed blood sample. In one embodiment, the device includes a base and a cover which are affixed together to create a test cartridge which has a substantially flat and low profile design. A lancet carrier is disposed between the base and the cover and includes a anchor fixedly mounted on the base and a lancet support member which is slidably mounted on the base, the anchor and the lancet support member being connected by a spring. A lancet is removably mounted on the lancet support member is disposed directly beneath an analyte test strip which secured to the underside of the cover.Type: GrantFiled: July 31, 2007Date of Patent: March 3, 2015Assignee: Abbott Diabetes Care Inc.Inventors: Chad Harold Mace, Andrea Nicolaisen, Damon H. Dehart
-
Patent number: 8968207Abstract: Method and apparatus are provided for computing signals related to cardiac output from physiologic input signals related to circulatory pressures or flows. Method and apparatus are provided for constructing a transforming filter and applying said filter to the physiologic input signals in order to obtain a signal proportional to phasic cardiac output or time-averaged cardiac output. This invention provides a means for real-time monitoring of cardiac output and stroke volume which is of great clinical importance but not otherwise feasible by present techniques.Type: GrantFiled: April 13, 2009Date of Patent: March 3, 2015Assignee: Massachusetts Institute of TechnologyInventor: Richard J. Cohen