Patent number: 11834515
Abstract: The compounds of the present invention are represented by the following compounds having Formula I and Formula (I?): where the substituents R1, R2, R2?, R3, R4, R5, R?, R?, X, Y, and Z are as defined herein and where the substituents R1, R2, R3, R4, R5, R?, R?, X, Y, and Z are as defined herein. These compounds are used in the treatment of bacterial infections, parasite infections, fungal infections, cancer, immunologic disorders, autoimmune disorders, neurodegenerative diseases and disorders, inflammatory disorders, or muscular dystrophy or for providing immunosuppression for transplanted organs or tissues.
Type:
Grant
Filed:
October 11, 2018
Date of Patent:
December 5, 2023
Assignees:
CORNELL UNIVERSITY, TRI-INSTITUTIONAL THERAPEUTICS DISCOVERY INSTITUTE
Inventors:
Gang Lin, Carl Nathan, Laura Kirkman, Wenhu Zhan, Trevor Morgan, Kenjiro Sato, Ryoma Hara, Masanori Kawasaki, Toshihiro Imaeda, Akinori Toita, Rei Okamoto, Takafumi Yukawa, Kazuyoshi Aso, Tzu-Tshin Wong, John D. Ginn, Michael A. Foley