Abstract: A catheter integral with a valved needle-free connector provides a safety catheter device configured to receive a blunt cannula and sharp needle forming an insertion mechanism. The sharp needle is mounted within a needle tube and a control handle is used to slide the sharp needle out of and into the protective needle tube. When the insertion mechanism is mounted to the connector and the control handle is used to slide the sharp needle out of the tube, a blunt cannula first moves into contact with and enters the bore of the valve mechanism of the connector opening it and protecting it from damage that may be caused by the sharp needle. The sharp needle is then extended through the connector and extends out the distal end of the catheter so that a venipuncture procedure may be performed to properly locate the catheter in the patient's circulatory system. Once located, the needle may be retracted into the insertion mechanism, the insertion mechanism disconnected from the connector, and discarded.

Abstract: A device for delivering a number of predetermined amounts of medicament includes a body having proximal and opposite distal ends, extending along a longitudinal axis, and configured to hold a medicament container; a driver in the body configured to act on a held container; a manually movable activation member arranged on the distal end; a biased actuator member movable by the activation member along the longitudinal axis and configured to protrude a distance from a distal end of the activation member and to interact with the driver when the actuator member is moved the distance toward the proximal end for delivering a predetermined amount; and an actuator guide member arranged in the body and configured to interact with the activation member and actuator member such that the guide member is held in a position in the body and released from the position after a predetermined amount of medicament is delivered.

Abstract: A device and use thereof for supply of gas to an operational space configured to adjoin a temporarily open inner portion of a mammal during surgical operations. The device includes a supply conduit, connectable to the gas source including an outlet end, and a body having at least partly an annular shape extending along a circumferential path around centre axis enclosing the operational space. The body has an inner side, outer side, an open interior channel, and an opening allowing the gas to enter the body from the supply conduit. The body is manufactured in foam rubber-like material having large number of open cells functioning as supply nozzles permitting the supply of a substantially laminar, continuous gas stream into the operational space enabling the formation of a gas cushion in the operational space.

Abstract: A flow control apparatus and method for accurate detection of occlusion conditions in a feeding set. A sensor is arranged with respect to a pumping device to produce a signal indicative of pressure in the feeding set. A control circuit that may receive the sensor signal from the sensor indicative of the pressure in the feeding set may also control operation of the pumping device. The control circuit is configured to operate the pumping device in an operational state, and in a reset state subsequent to the operational state in which the pumping device does not produce a pumping action and the pumping device is moved to a position in which the pumping device does not block the feeding set to permit fluid flow in a backflow direction opposite to the patient direction thereby relieving any built up pressure in the feeding set downstream of the pumping device.

Abstract: This document relates to catheter-based therapeutic apparatus and methods for directing therapy within the body of a subject. This document also encompasses a control handle comprising a steering assembly and a delivery assembly suitable for use in conjunction with the catheter-based therapeutic apparatus to provide steering and fine positional control of the catheter tip.

Abstract: Some embodiments of a medical device anchor system include an anchor device, a tether, and an adapter for securing a medical instrument (such as a catheter or the like) in place relative to a skin penetration point using subcutaneous anchors.

Abstract: A medical device control handle has with a distal component which is adjustable by an actuator assembly by means of a puller member or wire. The actuator assembly includes a user interface rotational dial, a detent tab washer and a spool, where the dial is rotationally coupled to the detent tab washer which transmits rotational movement of the dial to the spool. The spool has a shaft body and a drum end onto which an proximal end portion of the puller member can be wound to manipulate or adjust the distal component. Rotational movement of the detent washer is limited to prevent overrotation and breakage of the puller member. At least one washer is mounted on the shaft body of the spool to help apply compression load on the actuator assembly in friction-inducing contact with one or more components of the actuator assembly.

Abstract: The present disclosure provides devices and uses thereof. A devices disclosed herein comprises a plurality of microneedles adapted to protrude from the device. In some embodiments, a device is dimensioned and constructed to carry a payload, so that the payload can be delivered to an internal tissue of a subject or through a wall of a vessel after interaction with microneedles. In some embodiments, devices can be used for oral or intravenous administration. In some embodiments, devices can be used for implantation such as vaginal, rectal, urethral or bladder suppository or pessary.

Abstract: A radiopaque balloon with a composite wall having a radiopaque adhesive affixing inner and outer layers of the balloon. The radiopaque adhesive provides a radiographic image of the balloon wall with or without the use of a radiopaque contrast media to inflate the balloon. A radiographically fainter image is provided as the balloon is inflated with well-defined edges of a balloon image, and the total radiopacity of the balloon does not change as the balloon is inflated. Also, a method of imaging a balloon wall and a method of imaging a radiopaque adhesive between two layers of a balloon wall are provided.

Abstract: A catheter assembly with segmented or step-wise deployment stabilization system includes a base or handle, puncture needle extending from the handle, and a deployment mechanism or mechanisms to selectively extend from the distal end of the needle for first length a hollow stabilizing component and as a second step to a second further length a stabilizing guide wire element. The needle will gain sub-dermal access to the patient to the intended position for deployment of a catheter. Hollow stabilizing component provides for a first additional guide and support for a catheter sheath from the distal end of the needle. The stabilizing wire element provides additional length, guide and support for the catheter sheath. The hollow stabilizing component has some degree of flexibility as does the guide wire to minimize chance of damage to surrounding tissue.

Abstract: The invention provides a syringe for dispensing a drug (1), comprising: a rigid syringe body, —a first container (2), in contact with and enclosing the drug; and a second container (3), enclosing the first container, the second container being less gas permeable than the first container, wherein the second container partially or fully forms the rigid syringe body or is held within the rigid syringe body. The invention preserves the drug but allows the drug to be easily accessed without the need for a user to remove a gas barrier structure as a separate action in addition to the other actions needed to deliver the drug.

Abstract: A low-waste needle and syringe assembly for injecting a fluid into a patient is provided. The syringe has hatch marks printed on the outer wall of the body to indicate the amount of fluid and/or the concentration of the fluid contained in a fluid chamber of the syringe. A syringe tip defining a substantially frusto-conical interior void extends from an end wall of the syringe. A needle hub holds a needle and is configured so that the hub can be selectively and securedly attached to the syringe. A frusto-conical member of the needle hub matingly engages the frusto-conical void of the syringe tip when the hub is secured to the syringe, forming a fluid-tight seal. A plunger positioned in the fluid chamber can be depressed by a user, and a piston cap attached to the plunger urges fluid in the chamber out of the chamber through the syringe tip and into the needle. The piston cap matingly engages the end wall of the syringe so that substantially all fluid is urged from the chamber to the needle.

Abstract: A respiratory device comprising a housing enclosing a chamber and an orientation indicator moveable with respect to the housing between a first position indicative of an orientation of the housing predetermined to be suitable for operation of the respiratory device, and a second position indicative of an orientation of the respiratory device predetermined to be less suitable for operation of the respiratory device. The orientation indicator is positioned in a location on the respiratory device visible to a user during the operation of the respiratory device.

Abstract: In some aspects, systems, devices, and techniques for programming a medical fluid delivery device are described. In one example, the disclosure relates to a system including a medical fluid delivery device configured to deliver a therapeutic agent to a patient, and a processor. The processor may be configured to receive a proposed therapy dosing program that defines a fluid therapy for delivery to a patient via a medical fluid delivery device for a first period of time, determine a total dosage over a second period of time, where the second period of time at least partially overlaps the first period of time, and compare the total dosage over the second period of time to a reference dosage.

Abstract: An infusion pump for infusing a fluid from a syringe, the syringe comprising a syringe barrel and a syringe plunger comprising a piston, a plunger stem and a plunger flange, wherein the infusion pump comprises a housing having a display, a syringe retainer for retaining the syringe in place and a plunger driver for pushing the syringe plunger to expel fluid from the syringe, characterized in that the syringe retainer retains the syringe in a position such that at least a visible part of the display is located behind the syringe barrel. An array of infusion pumps and a docking station for docking infusion pumps is also described.

Abstract: Systems and methods are disclosed herein for prophylactic application of near-infrared optical energies and dosimetries to photo-biologically inhibit accelerations or intensifications in biofilm production, after a bacterial or fungal pathogen is challenged with an antibiotic or antifungal agent. This photo-biologic minimum biofilm inhibitory concentration (PMBIC) of infrared light will lower the minimum inhibitory concentration (MIC) necessary of an antibiotic and/or antifungal molecule necessary to decrease bacterial and fungal pathogens in human tissues. These systems and methods will only target undesirable microbial cells.

Abstract: A system for detecting and removing a gas bubble from a vascular infusion line, the system comprising: a disposable cassette adapted for disposition intermediate the fluid line, the disposable cassette comprising: a body comprising an inlet port, a chamber, an outlet port, and a purge port, a first passageway connecting the inlet port to the chamber, the first passageway comprising a first bubble detection section where a gas bubble may be detected within the first passageway, a second passageway connecting the chamber with the outlet port, and a first pinch valve disposed along the second passageway intermediate the chamber and the outlet port, and a third passageway connecting the chamber with the purge port, the third passageway comprising a second bubble detection section where a gas bubble may be detected within the third passageway, and a second pinch valve disposed along the third passageway intermediate the chamber and the bubble detection section.

Abstract: A device for expression and collection of breast milk includes an actuatable assembly and a breast interface. The breast interface is sized to receive a breast and form a fluid tight seal against the breast. The breast interface includes an expandable membrane disposed within at least a portion of the breast interface. The expandable membrane reversibly deforms in response to actuation of the actuatable assembly, thereby applying vacuum pressure at the breast to express milk. The expandable membrane comprises a plurality of expandable pleats which extend radially outward from a central longitudinal axis of the breast interface.

Abstract: A catheter port adapted to be selectively secured topically to a patient's body about a site at which a catheter is to be inserted into the patient's body. The catheter port includes a cushion adapted to be secured to the patient's epidermis at its bottom surface about the site and at its top surface to a member, an inner tube having one portion mounted on the member and having another portion that is adapted to extend into the patient's body about the site for guiding movement of a catheter relative to the site and for preventing any portion of the catheter from ever contacting the patient's epidermis, an outer tube having a proximal end mounted on one of the member and inner tube, an intermediate portion extending away from the one of the member and the inner tube in a distal end and a septum mounted on the outer tube.

Abstract: A first sponge device for use to manipulate and prepare the surface of the epithelium of an eye prior to application of an ophthalmic solution has a handle and a sponge head secured to the handle. The head is made of an absorbent, wicking sponge material and has a non-sharp, tissue preparation surface of predetermined shape for rubbing across the surface of the epithelium layer in order to manipulate the tissue. After the surface is prepared, a second, holding sponge is placed over the eye to act as a reservoir and to hold ophthalmic solution against the eye surface.