Abstract: Devices for the occlusion of body cavities, such as the embolization of vascular aneurysms and the like, and methods for making and using such devices. The devices may be comprised of novel expansile materials, novel infrastructure design, or both. The devices provided are very flexible and enable deployment with reduced or no damage to bodily tissues, conduits, cavities, etceteras.

Abstract: The invention relates to a method for forming a catalyzed dye system. The method includes the successive steps of (1) forming a mixture comprising at least one dye precursor and a catalyst and (2) adding an alkalizer to the mixture, which forms a catalyzed dye system. The dye system may be exposed to hair for less time than standard oxidative dye systems, which is believed to result in reduced damage to hair.

Abstract: Disclosed herein are methods of improving skin appearance associated with skin aging. The method comprises the step of applying an anti-aging bioactive composition to a skin surface having at least one sign of aging. The anti-aging bioactive composition is applied for a period of time sufficient to improve the appearance of the at least one sign of aging. In one embodiment, the anti-aging bioactive composition comprises an effective amount of a Nelumbo nucifera (Sacred Lotus) serum fraction. In another embodiment, the anti-aging bioactive composition comprises an effective amount of a Chamomilla recutita (German Chamomile) Flower serum fraction. In other embodiments, the anti-aging bioactive composition can further include a dermatologically acceptable carrier.

Abstract: Embodiments described herein generally relate to medicinal compositions (e.g., compositions comprising an active pharmaceutical agent) such as those comprising liquid hydrogen and/or hydrogen gas. In certain embodiments, the composition comprises hydrogen and/or noble gas(es) in a medicinal composition, for example, within the aqueous phase (e.g., dissolved). For example, in some cases, the medicinal composition may comprise an active pharmaceutical ingredient and hydrogen (H2) and/or noble gas(es). The noble gas may be, for example, xenon, argon, or the like. In some embodiments, the hydrogen and/or the noble gas(es) may infuse with the composition (e.g., such that at least a portion of the hydrogen gas and/or noble gas(es) is dissolved within the composition). Such compositions comprising hydrogen gas and/or noble gas(es) may be useful, for example, for the treatment of animal and human diseases, for improvement in athletic performance, for the enhancement of the overall health of a subject, or the like.

Abstract: The present invention relates to methods and compositions for treating lymphangioleiomyomatosis in a human subject in need of such treatment. The methods comprise administering to the subject via inhalation an aerosol composition comprising rapamycin or a prodrug or derivative (including analog) thereof.

Abstract: The invention relates to a biocidal composition containing 5-chlorine-2-methylisothiazolin-3-one and at least one other component selected from the group consisting of 1,2-benzisothiazolin-3-one, 2-bromine-2-nitropropane-1,3-diol and zinc. The claimed biocidal composition is characterized in that it contains methyl-4-isothiazolin-3-one in the region of between 0-2 wt. %, in relation to the total proportion of 5-chlorine-2-methyl-4-isothiazolin-3-ones. The invention also relates to the use of the claimed biocidal compositions for conserving technical products.

Abstract: The present invention comprises systems, methods and devices for the delivery of compositions for occluding or of means for opening conduits. The implantable occlusive material may be delivered pre-formed or in situ cured and, may be a resorbable material that supports tissue ingrowth that eventually replaces the material leaving little or no original material in place. The delivery system is positioned to allow for placement of the occlusive material into the body conduit. Use of delivery systems, methods and devices for re-opening an occluded body conduit are also included.

Abstract: A liquid cleansing composition and a method of manufacturing the same are disclosed. The liquid cleansing composition includes a cleansing component and an antibacterial system. The antibacterial system includes an antibacterial agent and an antibacterial enhancing agent. The weight ratio of the antibacterial agent to the antibacterial enhancing agent is greater than or equal to 0.30:1 and less than or equal to 0.65:1.

Abstract: Provided is an injectable implant configured to fit at or near a bone defect to promote bone growth, the injectable implant comprising lyophilized demineralized bone matrix (DBM) being in fiber and particle forms; alginate; and a liquid carrier, wherein the DBM is in an amount of about 20 wt. % to about 40 wt. % of a total weight of the injectable implant, the alginate is in an amount of from about 3 wt. % to about 10 wt. % of the total weight of the injectable implant, and the liquid carrier is in an amount from about 50 wt. % to about 70 wt. % of the total weight of the injectable implant. A moldable implant and methods of making the implants are further provided.

Abstract: The present invention relates to an oral film consisting essentially of dexamethasone and hydroxypropyl methylcellulose, wherein the concentration of dexamethasone is 30% w/w or more and the concentration of hydroxypropyl methylcellulose is between 35 and 70% w/w based on total dry matter.

Abstract: The present invention relates to a composition comprising: a) at least one sebum-absorbing powder with a sebum uptake of greater than or equal to 35 ml/100 g, and/or at least one styling powder; b) at least one zinc salt other than the sebum-absorbing powders with a sebum uptake of greater than or equal to 35 ml/100 g, and/or than the styling powders; c) optionally a propellant. A subject of the present invention is also to a process for the thy-washing and cosmetic treatment of keratin materials, comprising a step of applying the composition to the hair.

Abstract: A method for producing a polycondensate powder dispersion, characterised in that it includes at least one step of polycondensation: i) of at least one diester and at least one diamine, and/or ii) at least one amino ester, while stirring, in a solvent that can solubilise both the diamine and the diester and/or the amino ester but not the polyamide that forms during the polycondensation, at a temperature between 30° C. and the boiling temperature of the solvent, in order to produce a powder precipitate dispersed in the solvent.

Abstract: The present invention relates to premixes for the production of active compound-containing tablets which comprise polyvinyl alcohols (PVAs). The invention also relates to active compound-containing tablets which comprise a corresponding premix.

Abstract: The present disclosure relates to a composition for transduction of a virus in a cell by using a crosslinked product of PEGylated magnetic nanoparticles and catechol grafted poly-L-lysine by application of an external magnetic field. When the composition is used, a virus may be delivered into cells more rapidly and efficiently than in intracellular uptake of a virus by CAR-mediated endocytosis.

Abstract: An aqueous disinfectant formulation comprising at least one phenolic compound of natural origin; a surfactant sufficient to form a solution or dispersion of the essential oil in an aqueous carrier; a solvent, and sufficient water to make 100 weight percent is described herein.

Abstract: An aqueous liquid suspension containing a coated drug-ion exchange resin complex comprising a core composed of an amphetamine complexed with a pharmaceutically acceptable ion-exchange resin and an uncoated amphetamine-ion exchange resin complex is provided. The coated amphetamine-ion exchange resin complex is in admixture with a polymer to form a matrix. Methods of making the coated complex and the liquid suspension are described.

Abstract: Methods for producing cellulose articles having controlled release of active ingredient include dispersing pulp in aqueous direct solvent for cellulose to form a slurry. Organically modified or ion-exchange-activated phyllosilicate is homogenized in a direct solvent for cellulose with exfoliation by shearing, then mixed with the slurried pulp. A mixture of active ingredient and a lipophilic matrix material or a water-in-oil (“W/O”) emulsion containing active ingredient is stabilized with thickener, converted into a gel-like paste, and mixed with the slurried pulp. Water is stripped from the mixture until all cellulose is dissolved, the mixture is formed into shaped articles, and dried. Exemplary active ingredients include cosmetic active ingredients, fat-soluble vitamins or apolar plant extracts. Domains of active ingredient and matrix material or emulsion containing active ingredient are present as fine divisions within the inventive articles.

Abstract: The present invention provides for a method of improving the release of non-steroidal anti-inflammatory drugs (NSAIDs) from a plaster or bandage comprising an adhesive layer with a pharmaceutically acceptable NSAID together with heparin or a heparinoid. The invention also provides for methods of reducing muscle hyperalgesia in subjects without spontaneous pain.

Abstract: Compositions of small molecules, matrices, and isolated cells including methods of preparation, and methods for differentiation, trans-differentiation, and proliferation of animal cells into the osteoblast blast cell lineage were described. Examples of osteogenic materials that were administered to cells or co-cultured with cells are represented by compounds of Formula II, IV, and VI independently or preferably in combination with a matrix to afford bone cells. Small molecule-stimulated cells were also combined with a matrix, placed with a cellular adhesive or material carrier and implanted to a site in an animal for bone repair. Matrix pretreated with compounds of Formula II, IV, and VI were also used to cause cells to migrate to the matrix that is of use for therapeutic purposes.

Abstract: The present invention provides for a method of improving the release of non-steroidal anti-inflammatory drugs (NSAIDs) from a plaster or bandage comprising an adhesive layer with a pharmaceutically acceptable NSAID together with heparin or a heparinoid. The invention also provides for methods of reducing muscle hyperalgesia in subjects without spontaneous pain.