Abstract: Disclosed herein are heart pumps that can include a catheter body and an impeller coupled with a distal end of the catheter body. The impeller can include a tip that is resealable or that includes a resealable member. The heart pump can also include a diffuser disposed between the distal end of the catheter body and the impeller, wherein the diffuser includes a flow directing surface.

Abstract: A scrubbing article including a substrate, a stain release coating and a texture layer. The stain release coating is applied to the substrate and is present over a at least a major surface of the substrate, and the texture layer is formed over the stain release coating opposite the substrate. In some embodiments, the texture layer is printed on to the stain release coating. The substrate can assume various forms, such as nonwoven, fabric (e.g., woven or knitted), foam, film and sponge material or combinations thereof.

Abstract: The present invention is directed to locating and imaging with a swallowable sensor device disposed in a patient. The swallowable sensor device transmits an acoustic signal from inside a patient's body. A plurality of sensing elements receive the acoustic signal. A computation module determines a location of the swallowable sensor device with respect to the plurality of sensing elements based on the acoustic signal received by at least a subset of the plurality of sensing elements. A three-dimensional image of an interior portion of the patient can also be formed based on the received acoustic signal. The three-dimensional image may be formed by stereoscopically displaying two two-dimensional images of the interior portion, wherein the two two-dimensional images correspond to the swallowable sensor device being located at two different locations. Alternatively, the three-dimensional image may be formed by computing three-dimensional pixels of the interior portion.

Abstract: A system and associated processes may perform a memory access operation that includes receiving a data packet comprising a command of a type of a plurality of types of commands. The processes may include initiating a decoding of a first portion of the command, and automatically speculating as to the type of the command. Based on the speculation as to the type of the command, a bank activate command may be generated before the data packet is entirely decoded or received.

Abstract: One or more memory systems, architectural structures, and/or methods of storing information in memory devices is disclosed to improve the data bandwidth and or to reduce the load on the communications links in a memory system. The system may include one or more memory devices, one or more memory control circuits and one or more data buffer circuits. In one embodiment, the Host only transmits data over its communications link with the data buffer circuit. In one aspect, the memory control circuit does not send a control signal to the data buffer circuits. In one aspect, the memory control circuit and the data buffer circuits each maintain a separate state machine-driven address pointer or local address sequencer, which contains the same tags in the same sequence. In another aspect, a resynchronization method is disclosed.

Abstract: A speaker system uses multiple sound chambers having phi ratios to create a dampening effect to filter out incoherent sounds, thus creating an enhanced listening experience that feels very natural to the listener. The speaker system has at least a sound driver, a first sound chamber having a first volume, and a second sound chamber having a second volume that is approximately 1.6 times the first volume. The speaker system can also have a second sound driver, and a third sound chamber having a third volume that is that is approximately 1.6 times the second volume.

Abstract: The present invention relates to B7-H4-specific compositions and methods of use thereof.

Abstract: Disclosed herein are heart pumps that can include a catheter body and an impeller coupled with a distal end of the catheter body. The impeller can include a tip that is resealable or that includes a resealable member. The heart pump can also include a diffuser disposed between the distal end of the catheter body and the impeller, wherein the diffuser includes a flow directing surface.

Abstract: An integrally formed bucket and external organizer is provided. A bucket is provided having a tubular sidewall with an open upper end and a closed bottom end. An integrally formed brim connects to an outside surface of the tubular sidewall proximate to the open upper end. The brim extends radially outward from the tubular sidewall to an external or exterior edge. The brim includes a plurality of apertures that extend though its surface (e.g., between an interior edge attached to the tubular sidewall and the exterior edge). Such apertures may support various items (e.g., tools, fishing gear, etc.).

Abstract: The use of genes or biomarkers to more accurately diagnose aggressive prostate cancer in men of African descent or European descent is provided. More specifically, the genes or biomarkers of the present invention can be used in diagnostic tests and methods to determine, qualify, and/or assess aggressive prostate cancer or status, for example, to diagnose or identify aggressive prostate cancer, in an individual, subject, or patient, such as men of African descent or men of European descent.

Abstract: A painted vehicle trim component such as a spoiler, side-view mirror housing, or other vehicle body part is provided with electroluminescent paint to emit light from its surface. The trim component includes a substrate having a mounting surface for attaching to the vehicle. A conductor body is at least partially embedded in the substrate to provide a conductive surface exposed externally of the substrate. A conductive wire is crimped to the conductor body and is adapted to connect to an electrical power source remotely from the vehicle trim component. A conductive bus bar paint layer is deposited over the substrate and onto the exposed conductive surface of the conductor body. A light-emitting paint layer deposited over the substrate is disposed relative to the conductive paint layer such that light is emitted when an electrical signal is received at the conductive wire.

Abstract: Elongated scalar coils modify or enhance the audio quality and of a speaker system and its auditory effects on a user. A scalar coil has two spiral windings with opposite winding directions. Scalar coil is in series with an input of the speaker to change the sound signature and to reduce digital noise. Scalar coil is also in series with a laser emitter that produces a laser beam that travels through the scalar coil, which produce electromagnetic forces that improve perceived audio quality in a user.

Abstract: A system and associated processes may perform a memory access operation that includes receiving a data packet comprising a command of a type of a plurality of types of commands. The processes may include initiating a decoding of a first portion of the command, and automatically speculating as to the type of the command. Based on the speculation as to the type of the command, a bank activate command may be generated before the data packet is entirely decoded or received.

Abstract: The invention provides compositions and methods for treating ovarian cancer. Specifically, the invention relates to administering a genetically modified T cell having ?-folate receptor (FR?) binding domain and CD27 costimulatory domain to treat ovarian cancer. In an embodiment, the FR? binding domain is fully human, thereby preventing a host immune response.

Abstract: The present invention relates to compositions and methods comprising a single viral vector comprising both a first polynucleotide comprising a constitutive promoter operably linked to a nucleic acid encoding at least one transgene, wherein one of the at least one transgenes encodes a receptor or receptor subunit, a receptor fusion protein or a fluorescent marker; and a second polynucleotide comprising an inducible promoter operably linked to a nucleic acid encoding an effector. Also provided are engineered cells comprising the viral vector and methods for generating the engineered cells comprising the viral vector. Also provided is site-specific integration of the genetic element into the a gene locus by means of a CRISPR-related system. Further provided are methods for treating a patient having a disease, a disorder or condition associated with expression of an antigen, the method comprising administering to the patient an effective amount of a composition comprising the engineered cell.

Abstract: The invention includes compositions and methods to rapidly isolate and culture cells that are potent for use in adoptive immunotherapy. In one embodiment, the isolated cells of the invention are tumor infiltrating lymphocytes (TIL) that express CD137 (also known as 4-1BB and TNFSFR9).

Abstract: Apparatus and methods for creating a sensation in which a sound driver emits sound waves according to incoming information, and one or more light emitters emit light waves with varying patterns according to amplitude and frequency changes in the incoming information. Preferably, only low frequency signals (below 50 Hz) are used to produce the pattern of the light waves, which are directed directly towards the tympanic membrane without any artificial barrier. Emitted light preferably reaches the inner ear region substantially simultaneously with emitted sound waves. A second light emitter can be used to emit light waves that are complementary to, and preferably between 175 and 185 degrees out of phase with, the light waves from the first light emitter, to produce scalar waves.

Abstract: A painted vehicle trim component such as a spoiler, side-view mirror housing, or other vehicle body part is provided with electroluminescent paint to emit light from its surface. The trim component includes a substrate having a mounting surface for attaching to the vehicle. A conductor body is at least partially embedded in the substrate to provide a conductive surface exposed externally of the substrate. A conductive wire is crimped to the conductor body and is adapted to connect to an electrical power source remotely from the vehicle trim component. A conductive bus bar paint layer is deposited over the substrate and onto the exposed conductive surface of the conductor body. A light-emitting paint layer deposited over the substrate is disposed relative to the conductive paint layer such that light is emitted when an electrical signal is received at the conductive wire.

Abstract: An adapter for a bearing race and seal driver tool that allows the tool to be used in hard to reach applications. The adapter connects to a driver and a handle at a non-zero angle, for example a right angle, to allow the adapter to be struck at a face of the adapter rather than the handle to be struck at an end of the handle. A pocket is included at one or more connection points between the adapter and the handle or driver to resist rotational movement of the handle or driver.

Abstract: The invention provides compositions and methods for treating ovarian cancer. Specifically, the invention relates to administering a genetically modified T cell having ?-folate receptor (FR?) binding domain and CD27 costimulatory domain to treat ovarian cancer. In an embodiment, the FR? binding domain is fully human, thereby preventing a host immune response.