Abstract: The inventive waveguide structure comprises a first waveguide region having a constant first width adapted to guide electromagnetic waves mode sustainably along its longitudinal axis; a second waveguide region adapted to guide electromagnetic waves mode sustainably along its longitudinal axis, wherein the longitudinal axis of the first waveguide region and the longitudinal axis of the second waveguide region form a common longitudinal axis of the waveguide structure, wherein a first end face of the first waveguide region and a first end face of the second waveguide region are aligned with each other, the width of the first end face of the second waveguide region corresponding to the first width, and the width of the second waveguide region along its longitudinal axis widens from the first end face to a second end face to a second width greater than the first width.

Abstract: The present invention relates to novel compounds of the formula (I) that can be employed in the selective Tau detection of disorders and abnormalities associated with Tau aggregates such as Alzheimer's disease and other tauopathies using Positron Emission Tomography (PET) Imaging.

Abstract: The present invention relates to novel compounds of the formula (II) that can be employed in the selective Tau detection of disorders and abnormalities associated with Tau aggregates such as Alzheimer's disease and other tauopathies using Positron Emission Tomography (PET) Imaging.

Abstract: A liner for a prosthesis includes an inner face and an outer face, at least one flow channel with at least one inlet opening and at least one outlet opening extending between the inner face and the outer face, and a one-way valve arranged in the course of the at least one flow channel in such a manner that a fluid can flow through it only from the at least one inlet opening towards the at least one outlet opening.

Abstract: A prosthetic liner, prosthesis socket or orthosis with a base body, which has a volume through which gas can flow and which comprises at least one supply line and at least one evacuation line, wherein at least one compressed gas source, which is connected or can be connected to the at least one supply line such that an activation of an activation element causes compressed gas to flow out of the compressed gas source through the volume and at least partially cools the base body.

Abstract: Methods for driving a tunable laser with integrated tuning elements are disclosed. The methods can include modulating the tuning current and laser injection current such that the laser emission wavelength and output power are independently controllable. In some examples, the tuning current and laser injection current are modulated simultaneously and a wider tuning range can result. In some examples, one or both of these currents is sinusoidally modulated. In some examples, a constant output power can be achieved while tuning the emission wavelength. In some examples, the output power and tuning can follow a linear relationship. In some examples, injection current and tuning element drive waveforms necessary to achieve targeted output power and tuning waveforms can be achieved through optimization based on goodness of fit values between the targeted and actual output power and tuning waveforms.

Abstract: The present invention relates to novel compounds that can be employed in the selective Tau detection of disorders and abnormalities associated with Tau aggregates such as Alzheimer's disease and other tauopathies using Positron Emission Tomography (PET) Imaging.

Abstract: The present invention relates to a composition comprising at least one carrier comprising a polysaccharide, at least one antioxidant and at least one amino acid selected from cysteine, lysine, alanine and arginine. It also relates to the use of such a composition for the protection of microorganisms during drying, storage and/or reconstitution, to a culture powder, to a process of making the culture powder and to products comprising the culture powder.

Abstract: Disclosed is a Vernier effect DBR laser that has uniform laser injection current pumping along the length of the laser. The laser can include one or more tuning elements, separate from the laser injection element, and these tuning elements can be used to control the temperature or modal refractive index of one or more sections of the laser. The refractive indices of each diffraction grating can be directly controlled by temperature changes, electro optic effects, or other means through the one or more tuning elements. With direct control of the temperature and/or refractive indices of the diffraction gratings, the uniformly pumped Vernier effect DBR laser can be capable of a wider tuning range. Additionally, uniform pumping of the laser through a single electrode can reduce or eliminate interfacial reflections caused by, for example, gaps between metal contacts atop the laser ridge, which can minimize multi-mode operation and mode hopping.

Abstract: A prosthesis liner for placing on a stump includes an elastic main body which has a proximal opening for inserting the stump into a receiving space, and a distal end. At least one suction cup is arranged on the outside of the prosthesis liner.

Abstract: Methods for driving a tunable laser with integrated tuning elements are disclosed. The methods can include modulating the tuning current and laser injection current such that the laser emission wavelength and output power are independently controllable. In some examples, the tuning current and laser injection current are modulated simultaneously and a wider tuning range can result. In some examples, one or both of these currents is sinusoidally modulated. In some examples, a constant output power can be achieved while tuning the emission wavelength. In some examples, the output power and tuning can follow a linear relationship. In some examples, injection current and tuning element drive waveforms necessary to achieve targeted output power and tuning waveforms can be achieved through optimization based on goodness of fit values between the targeted and actual output power and tuning waveforms.

Abstract: A method of controlling beam quality and stability of a laser apparatus, the laser apparatus comprising, a diode laser (10) providing first radiation of at least a first wavelength, and a frequency conversion unit (12) configured to frequency-convert the first radiation from the diode laser and to output the frequency-converted radiation (213), the frequency-converted radiation having at least a second wavelength different from the first wavelength, the diode laser (10) comprising at least a first and a second section (222,223), a first contact (220) for injecting a first current (I1) into the first section (222), a second contact (221) for injecting a second current (I2) into the second section (223), and means for controlling a temperature of the diode laser; wherein the method comprises monitoring a first parameter indicative of the power content of a dominant lobe of the first radiation; iteratively determining a combination of respective values of the first current, the second current and the temperature

Abstract: A liner for a prosthesis includes an inner face and an outer face, at least one flow channel with at least one inlet opening and at least one outlet opening extending between the inner face and the outer face, and a one-way valve arranged in the course of the at least one flow channel in such a manner that a fluid can flow through it only from the at least one inlet opening towards the at least one outlet opening.

Abstract: A device for connecting a pump, having a through-hold provided in a prosthesis shaft, wherein the device comprises at least one channel having a first outlet for connecting to the through-hole in the prosthesis shaft and a second outlet which can be connected to the pump and at least one valve, wherein the valve can be switched to a first mode and to a second mode, and the valve is a one-way valve in the first mode and a two-way valve in the second mode.

Abstract: A prosthetic liner for application on a stump, comprising an elastic base, which has a proximal opening for insertion of the stump in a receiving space, and a distal end. At least one pneumatic piston is arranged on the outer face of the prosthetic liner.

Abstract: This invention relates to novel compounds suitable for labeling by 18F and to the corresponding 18F labeled compounds themselves, 19F-fluorinated analogs thereof and their use as reference standards, methods of preparing such compounds, compositions comprising such compounds, kits comprising such compounds or compositions and uses of such compounds, compositions or kits for diagnostic imaging by Positron Emission Tomography (PET).

Abstract: The invention relates to a prosthesis liner for placing on a stump, with an elastic main body which has a proximal opening, for inserting the stump into a receiving space, and has a distal end, wherein at least one sucker is arranged on the outside of the prosthesis liner.

Abstract: This invention relates to homoglutamic acid derivatives suitable for labeling or already labeled with 18F or 19F, methods of preparing such compounds, compositions comprising such compounds, kits comprising such compounds or compositions and uses of such compounds, compositions or kits for diagnostic imaging.

Abstract: A method of controlling beam quality and stability of a laser apparatus, the laser apparatus comprising, a diode laser (10) providing first radiation of at least a first wavelength, and a frequency conversion unit (12) configured to frequency-convert the first radiation from the diode laser and to output the frequency-converted radiation (213), the frequency-converted radiation having at least a second wavelength different from the first wavelength, the diode laser (10) comprising at least a first and a second section (222,223), a first contact (220) for injecting a first current (I1) into the first section (222), a second contact (221) for injecting a second current (I2) into the second section (223), and means for controlling a temperature of the diode laser; wherein the method comprises monitoring a first parameter indicative of the power content of a dominant lobe of the first radiation; iteratively determining a combination of respective values of the first current, the second current and the temperature

Abstract: This invention relates to novel compounds suitable for labeling by 18F and to the corresponding 18F labeled compounds themselves, 19F-fluorinated analogues thereof and their use as reference standards, methods of preparing such compounds, compositions comprising such compounds, kits comprising such compounds or compositions and uses of such compounds, compositions or kits for diagnostic imaging by Positron Emission Tomography (PET).