Abstract: Disclosed are compounds of formula (I) below or a stereoisomer, a tautomer, or a pharmaceutically acceptable salt thereof: in which each of variables each of variables R, R1, R2, X1, X2, X3 and n is defined herein. Also disclosed is a method for treating a cancer with a compound of formula (I) or a salt thereof and a pharmaceutical composition containing same.

Abstract: Recombinant chimeric bovine/human parainfluenza virus 3 (rB/HPIV3) vectors expressing Respiratory Syncytial Virus (RSV) G protein or a recombinant RSV G protein, as well as methods of their use and manufacture, are provided. The rB/HPIV3 vector comprises a genome comprising a heterologous gene encoding the RSV G protein or the recombinant RSV G protein. Nucleic acid molecules comprising the sequence of the genome or antigenome of the disclosed rB/HPIV3 vectors are also provided. The disclosed rB/HPIV3 vectors can be used, for example, to induce an immune response to RSV and HPIV3 in a subject.

Abstract: The present invention is related to a novel positive electrode active material for lithium-ion battery. The positive electrode active material is expressed by the following formula: Li1.2NixMn0.8-x-yZnyO2, wherein x and y satisfy 0<x?0.8 and 0<y?0.1. In addition, the present invention provides a method of manufacturing the positive electrode active material. The present invention further provides a lithium-ion battery which uses said positive electrode active material.

Abstract: The present disclosure relates to a 4D printed gripper with flexible finger joints and a trajectory tracking control method thereof. The 4D printed gripper with flexible finger joints includes: a palm unit and five finger units connected to the palm unit, where each finger unit includes two flexible finger joints and two phalanges; each flexible finger joint is divided into one upper layer and one lower layer of liquid crystal elastomer (LCE), and each LCE is used to implement a bidirectional bending movement of the finger unit. The present disclosure can precisely control the gripper with flexible finger joints.

Abstract: Technologies for a flexible three-dimensional power plane in a chassis are disclosed. In one embodiment, a flexible ribbon cable is laid along a circuit board tray. The flexible ribbon cable is secured to the tray using power bosses. The power bosses connect to one or more conductors on the ribbon cable. When the circuit board is mounted on the circuit board tray, the power bosses extend through holes in the circuit board and mate with power clips on the surface of the circuit board tray. The ribbon cable, power bosses, and power clips can distribute power to various locations on the circuit board, without requiring large traces that take up space on the circuit board.

Abstract: A control method for a lamp system based on RGB wiring arrangement includes outputting a first PWM signal through a connecting line and a second PWM signal through another connecting line; wherein, the first PWM signal is used for controlling an on/off time interval of a first switch device on the connecting line to generate a continuous variable level at two terminals of the resistor on the connecting line, the continuous variable level forms a digital signal, and the second PWM signal is used for controlling the second switch device on the another connecting line to be normally-off to provide a stable power supply; the lamps acquiring corresponding control information from the digital signal through ID matching; and after the control information is decoded by the decoding module, currents transmitted to the coloured light emitting modules being regulated to control the coloured light emitting modules.

Abstract: Provided herein are recombinant self-complementary adeno-associated virus (scAAV) nucleic acid vectors that comprise a ubiquitous eukaryotic promoter, such as elongation factor 1? (EF1?), chicken beta-actin (CBA), and hybrid chicken beta-actin (CBh), followed by a dominant negative RhoA. Also provided herein are methods of use of said vectors, including intraocular injections (e.g., intracameral injections) to reduce intra-ocular pressure (TOP). Also provided herein are plasmids, recombinant scAAV particles, compositions, formulations, and other methods of use related to such vectors.

Abstract: In some examples, for process-to-process communication, such as in function linking, a virtual channel can be provisioned to provide virtual machine to virtual machine communications. In response to a transmit request from a source virtual machine, the virtual channel can cause a data copy from a source buffer associated with the source virtual machine without decryption or encryption. The virtual channel provisions a key identifier for the copied data. The destination virtual machine can receive an indication data is available and can cause the data to be decrypted using a key accessed using the key identifier and source address of the copied data. In addition, the data can be encrypted using a second, different key for storage in a destination buffer associated with the destination virtual machine. In some examples, the key identifier and source address is managed by the virtual channel and is not visible to virtual machine or hypervisor.

Abstract: An enhancement mode high electron mobility transistor (HEMT) includes a group III-V semiconductor body, a group III-V barrier layer and a gate structure. The group III-V barrier layer is disposed on the group III-V semiconductor body, and the gate structure is a stacked structure disposed on the group III-V barrier layer. The gate structure includes a gate dielectric and a group III-V gate layer disposed on the gate dielectric, and the thickness of the gate dielectric is between 15 nm to 25 nm.

Abstract: Examples described herein relate to offload reliable transport management to a network interface device and store packets to be resent, based on received packet receipt acknowledgements (ACKs), into one or more kernel space queues that are also accessible in user space.

Abstract: A whole-vehicle-based method for evaluating extreme pressure and antiwear properties of grease includes injecting the grease onto a key bearing pin and causing the engineering machine to operate without load is disclosed. The method includes causing the engineering machine to operate under a load of 10% to 150% rated load at least once, viewing and analyzing a wear condition of a surface of the bearing pin, and issuing a whole-vehicle-based evaluation report of extreme pressure and antiwear properties of grease. The engineering machine is caused to operate once under a load of 10% to 150% rated load for 0.5 min to 100 h.

Abstract: The present application provides a perovskite solar cell, including conductive glass, a hole transport layer, a perovskite layer, an electron transport layer and a back electrode, where a passivation layer may be disposed between the hole transport layer and the perovskite layer, and the passivation layer may include an amide and/or a cation thereof, where the amide may include a compound of formula (1) and/or formula (2): where R1 and R2 are each independently selected from hydrogen, —R, —NR2, —NHR, —NH2, —OH, —OR, —NHCOR, —OCOR, and —CH2COOH, where R represents a straight or branched chain alkyl group having 1-10 carbon atoms, m is an integer of 0 to 10; and n is an integer of 1 to 10; and where Ar is selected from a C5-C10 aryl or heteroaryl group.

Abstract: The present invention relates to a balloon catheter and an ablation system. The balloon catheter includes a catheter body, a balloon, a temperature-sensing element and a restricting member. The balloon is disposed at a distal end of the catheter body. The temperature-sensing element includes a temperature-sensing module and a wire. The temperature-sensing module is disposed on the balloon or the catheter body, and part of the wire of the temperature-sensing element is arranged in a cavity of the catheter body so as to extend in an axial direction of the cavity of the catheter body. The restricting member is disposed within the cavity of the catheter body and configured to positionally restrict the wire of the temperature-sensing element within the cavity of the catheter body.

Abstract: A medical catheter and a medical device, including: a catheter assembly defining a needle channel comprising a distal section with a predefined position; a needle assembly (200) partially disposed in the needle channel and comprising a metal needle (210), the needle assembly (200) movable in an axial direction of the needle channel so that the metal needle (210) passes by or reaches the predefined position; a handle assembly (300) comprising a grip (310) and an advancement member, the advancement member connected to the grip (310) and configured to be moveable relative to the grip (310), the advancement member configured to drive the needle assembly (200) to move along the needle channel; and a first monitoring device configured to sense the arrival of the metal needle (210) at the predefined position and responsively generate a first target signal.

Abstract: A radio frequency communication method, a vehicle control method, a device, and a system are provided. The radio frequency communication method includes: acquiring a first response signal and a second response signal which are corresponding to a radio frequency tag, wherein the first response signal and the second response signal are respectively generated by the radio frequency tag responding to radio frequency signals of different powers; determining, based on the second response signal, positioning information of the radio frequency tag; and establishing, based on the positioning information and the first response signal, a communication connection to the radio frequency tag.

Abstract: Disclosed is a flexible surgical instrument system, comprising a flexible continuum structure consisting of a distal structure, a middle connecting body and a proximal structure linked in sequence, and further comprising a transmission driving unit linked to the proximal structure. The transmission driving unit comprises a plurality of transmission mechanisms respectively driving corresponding proximal segments. The transmission mechanisms are operable to control the direction of a bending plane of the proximal segments and to control the bending angle of the proximal segments in the bending plane, so as to drive the proximal segments in the proximal structure to bend or turn in any arbitrary direction, and to further drive distal segments in the distal structure linked thereto to bend or turn in the opposite direction.

Abstract: A microelectrode sensor for detecting Staphylococcus aureus and a preparation method and an application method thereof are provided. The microelectrode sensor is a three-electrode system sensor with a platinum wire electrode as a counter electrode and an Ag/AgCl electrode as a reference electrode, and a working electrode is a silver microelectrode modified by chitosan, catechol and Staphylococcus aureus aptamers. The microelectrode sensor is constructed based on the microelectrode with micro/nano structure on the surface, dual media (Fc-Ru3+), chitosan, and catechol. The working electrode can specifically capture Staphylococcus aureus. During the CV test of the microelectrode sensor, the Cl? in bacteria will be leaked to a surface of the working electrode under the action of local high-field strength, and when Cl? ions exists, the cathodic reduction peak of the working electrode can be specifically enhanced between 0 to ?0.1 V, the goal of specific detection of bacteria can be achieved.

Abstract: Provided are multi-arm polymer conjugates of Toll-Like Receptor (“TLR”) agonists such as TLR 7/8 agonists, as well as related compositions, and methods of making and using such conjugates. Exemplary conjugates are encompassed by Formula I: RQ-POLY-Xr-TLR7/8 AG)q??Formula I or a pharmaceutically acceptable salt form thereof, where R, taken together with each Q, is a residue of a polyol, polythiol, or polyamine bearing from 3 to about 50 hydroxyl, thiol, or amino groups; each Q is a linker selected from oxygen, sulfur and —NH; each POLY is independently a water-soluble, non-peptidic polymer; each Xr is independently a linkage-containing spacer moiety; q is a positive integer from 3 to about 50; and each TLR 7/8 AG is a Toll-like receptor 7/8 agonist.

Abstract: The invention provides a lighting fixture based on a DMX controller, and a control method. The lighting fixture includes an NFC address writer, a DMX controller for outputting light control data, NFC controllers receiving data from the DMX controller, and DMX lamps receiving data from the NFC controllers, wherein the DMX controller, the NFC controllers and the DMX lamps are electrically connected in sequence, the NFC address writer is used for modifying address information of the NFC controllers in real time, the NFC controllers selectively extract the light control data output by the DMX controller according to the address information and output the extracted light control data to the DMX lamps, and the DMX lamps change light according to the light control data received from the NFC controllers.

Abstract: An automatic biological sample library, includes a frame, an upper computer, a control system, a liquid nitrogen tank, an insulated chamber, a transfer container, a rotary-disk rotating module, a basket lifting module, a tray shoveling module, a tube picking module and a transfer module. The rotary-disk rotating module, the basket lifting module, the tray shoveling module, the tube picking module and the transfer module are electrically connected to the control system.