Abstract: Provided herein are dendrimers comprising: a core unit, five generations of building units which are lysine residues or analogues thereof, first terminal groups comprising a cabazitazel residue covalently attached to a diglycolyl linker group, and second terminal groups comprising a PEG group. Also provided herein are pharmaceutical compositions comprising the dendrimers, and methods and uses of the dendrimers in therapy of disorders such as cancers. Processes for making the dendrimers and intermediates are also provided.

Abstract: Methods and systems provide for augmenting images and displayed objects using extended reality (XR) images. Image data may be received that includes real-world image data displayed on a display of the client device, which is monitored by a guide software component, and XR images. A person may be identified from the real-world image data, and, in response to identifying the person, stored information may be retrieved from a record associated with the identified person in a database in communication with the client device. The guide software component may then modify the XR images in response to identifying the person to include the retrieved information associated with the identified person. Additional XR images may be used to provide informative content at spatial anchor locations within the real-world image data.

Abstract: A digital thermometer includes a first oscillator to generate a first clock signal, wherein a period of the first clock signal remains constant in view of changes in a temperature of the apparatus and a first counter coupled to the first oscillator, the first counter to count a fixed number of cycles of the first clock signal associated with a measurement period. The digital thermometer further includes a second oscillator to generate a second clock signal, wherein a period of the second clock signal varies with changes in the temperature and a second counter coupled to the second oscillator, the second counter to generate an output representing a count of a number of cycles of the second clock signal that occur during the measurement period. In addition, the digital thermometer includes calibration circuitry coupled to the second counter, the calibration circuitry to calibrate the output of the second counter to generate a value representing the temperature of the apparatus.

Abstract: Systems and methods for managing surgical sponges. A dispenser assembly coupled to a main support includes an internal or first storage location to removably receive a carton of sponge sorters, and an external or second storage location to removably support a carton of surgical draping. At least one arm may be supported on the housing and movable between an undeployed position and a deployed position. The arm may include weighing means to measure a weight of the surgical sponge being disposed in a sponge sorter supported by the arm. The arm may be a cantilever and abeam load cell may be disposed within a channel of a beam. A processor may determine fluid weight based on measured weight and dry weight correlated with the surgical sponge being counted out as detected with a data reader. The processor may estimate blood loss to be displayed on a display.

Abstract: A rotor lock assembly for locking a rotor of a wind turbine. The rotor lock assembly has at least one relocatable rotor lock. The relocatable rotor lock has a housing, a bushing element, a pin shaft position within the bushing element, and a locking mechanism. The housing includes a mounting portion adapted for mounting to a bearing housing adjacent to a rotor lock plate of the rotor.

Abstract: Techniques for providing domain name and URL visual verifications to increase security of operations on a device. The techniques include a visual indicator and/or warning to a user on the user's computing device that a domain or URL requested by the user and the device is unpopular, new, unknown, inauthentic, associated with malware or phishing, or in some other way, risky. The techniques include identifying a domain name in a communication received by a computing device and then determining a popularity ranking and/or an age of the domain name. The device can render, for display on a screen of the device, a visual indicator having the popularity ranking and/or the age of the domain name. Also, the techniques can include identifying a URL in a communication received by a computing device and then rendering, for display on a screen of the device, a visual indicator having the entire URL.

Abstract: The present invention relates to an indoor stand with degrees of movement side gear for use with bicycles comprising two main components assembled in an integrated manner: 1) a rear roller and 2) a front stand that attaches to the fork, instead of the front wheel, in which springs or cushions below the front fork allow degree of lateral movement to the left and right, in which a main bar is coupled to the base by an axis that allows the lateral movement degrees with stability. The presence of these components makes the present invention well simulate the experience of pedaling outdoors and working on the user's shoulders, arms and abdomen.

Abstract: A building system of a building including one or more memory devices having instructions thereon, that, when executed by one or more processors, cause the one or more processors to identify a capability of an entity in a building graph, the building graph including a plurality of nodes and a plurality of edges, the plurality of nodes representing entities of the building including the entity and the capability, the plurality of edges representing relationships between the entities of the building and the capability. The instructions cause the one or more processors to receive a command to perform an operation associated with the entity, the operation associated with the capability of the entity and provide the command to perform the operation associated with the entity to an operating system.

Abstract: A computing device provides enhancement of the capabilities of text messaging applications that execute on user devices. The computing device includes a processor that receives a text message via a network from a user device, the text message including a character representation of a product bundle of a merchant. The processor determines bundle data for the product bundle by referencing a database using the character representation. The processor provides one or more text messages via the network to the user device with transaction data including the bundle data, payment data, and shipping data. The processor receives a text message via the network from the user device confirming the transaction data. The user may use text commands presented by the computing device or natural language conversation in the text messages to the computing device to modify the transaction data and perform other ecommerce actions.

Abstract: Methods, systems, and devices for operating a user device are described. A user device may identify a health-related condition of a user based on a user input, PPG data for the user, or both. The user device may display instructions for performing a wellness routine that is configured to alleviate the health-related condition. The user device may acquire an additional user input, additional PPG data, or both, during a trial period for the wellness routine. The user device may display information associated with the wellness routine that is based on the additional user input, the additional PPG data, or both.

Abstract: A control panel for an appliance defines a display direction and includes a printed circuit board defining a first surface, a second surface opposite the first surface along the display direction, and a through hole passing through the printed circuit board from the first surface to the second surface. A console cover is mounted to the first surface of the printed circuit board, a standoff feature is positioned between the console cover and the printed circuit board to create a localized gap between the console cover and the printed circuit board, a retention feature engages the second surface to retain the printed circuit board against the console cover, and an electronic component mounted to the printed circuit board and having an electrical contact that extends through the through hole where it forms a connection joint that is positioned within the localized gap.

Abstract: The present disclosure relates to medicament injection devices. An injection device includes: a movable dosage programming component comprising a rotary encoder system having a predefined angular periodicity, a sensor arrangement including a first optical sensor configured to detect movement of the movable dosage programming component relative to the sensor arrangement during dosing of a medicament, wherein the first optical sensor is configured to operate in a strobe-sampling mode at a first frequency, a second optical sensor configured to detect movement of the rotary encoder system relative to the second optical sensor wherein the second optical sensor is configured to operate in a strobe-sampling mode at a second frequency lower than the first frequency, and a processor arrangement configured to, based on the detected movement, determine a medicament dosage administered by the injection device.

Abstract: A building system including one or more memory devices having instructions stored thereon, that, when executed by one or more processors, cause the one or more processors to receive an event from an event source, the event comprising data and a timestamp. The building system operates to identify first contextual data describing the event in a digital twin, the digital twin comprising a virtual representation of a building, enrich the event with the first contextual data, and provide the enriched event to a consuming system, the consuming system generating an output event based on the enriched event. The building system operates to identify second contextual data describing the output event in the digital twin, enrich the output event with the second contextual data, and provide the enriched output event to the consuming system or another consuming system.

Abstract: A personal protection system for providing a sterile barrier around medical/surgical personnel. The system includes a helmet over which a hood or a toga suspended. The helmet has a chin bar that extends forward of the face of the individual wearing the system. At least one manually actuated control for regulating one aspect of operation of the system is mounted to the chin bar. Sometimes the control is a button that is depressed to control the operation of a helmet mounted fan that draws air into the hood or toga. A microphone may also be mounted to the chin bar.

Abstract: A building system of a building including one or more memory devices having instructions thereon, that, when executed by one or more processors, cause the one or more processors to identify a capability of an entity in a building graph, the building graph including a plurality of nodes and a plurality of edges, the plurality of nodes representing entities of the building including the entity and the capability, the plurality of edges representing relationships between the entities of the building and the capability. The instructions cause the one or more processors to receive a command to perform an operation associated with the entity, the operation associated with the capability of the entity and provide the command to perform the operation associated with the entity to an operating system.

Abstract: A building system of a building including one or more memory devices having instructions thereon, that, when executed by one or more processors, cause the one or more processors to receive a request to access a portion of a building graph of the building from a system, the building graph including a plurality of nodes and a plurality of edges, the plurality of nodes representing entities of the building and the plurality of edges representing relationships between the entities of the building. The instructions cause one or more processors to determine whether the system has access to the portion of the building graph based on a policy indicated by the plurality of nodes and edges of the building graph and provide the portion of the building graph to the system in response to a determination that the system has access to the portion of the building graph.

Abstract: Techniques are disclosed relating to determining a similarity of components of a current webpage to different UI components for use in automatically generating an updated webpage. A computer system may receive information specifying a current webpage, including a particular current UI component and information specifying a plurality of different UI components for an updated webpage. The computer system may identify one or more characteristics of the particular current UI component. The computer system may determine, based on the identified one or more characteristics, a similarity of ones of the plurality of different UI components to the particular current UI component. The computer system may select, based on the determining, a particular different UI component from the plurality of different UI components for use, in the updated webpage, for the particular current UI component. Such techniques may advantageously improve user experience by automatically providing up-to-date user interfaces.

Abstract: A computing system includes a network interface circuit and a processing circuit configured to receive a plurality of issuer ratings associated with issuers from a plurality of analyst devices, wherein the plurality of issuer ratings include qualitative ratings, generate numerical quality ratings for the issuers based on the qualitative ratings of the issuers, receive a plurality of investment parameters from a manager device, the plurality of investment parameters defining characteristics of a custom investment strategy, generate a dataset regarding securities issued by the issuers based on the numerical quality ratings of the issuers, the dataset including securities issued by the issuers having a numerical quality rating over a pre-determined value, generate the custom investment strategy by selecting securities from the dataset based on the numerical quality ratings and the plurality of investment parameters, and provide the custom investment strategy to the manager device.

Abstract: System and methods for displaying one or more assets on a client device based on device characteristics are provided. Code is transmitted to a client device. The code, when executed by the client device, causes a processor of the client device to determine a first device characteristic of the client device. A first layout may be selected based on the first device characteristic. The layout may include one or more cards. Each card may correspond to one or more assets. Each card may be modified based on a corresponding card characteristic. One or more assets may be requested. The assets may be displayed on the first client device. The code may be transmitted to another client device, which may select a different layout based on a different device characteristic.

Abstract: Techniques are provided for controlling an output laser pulse signal of a medical device. A control device defines a time duration of capacitive discharge to a laser device. The time duration corresponds to an intended energy of the output laser pulse signal. The control device generates a plurality of sub-pulse control signals. The sub-pulse control signals define a series of capacitive discharge events of the capacitor bank. The control device modulates one or more of a sub-pulse control signal period or a sub-pulse time duration of the sub-pulse control signals to modify the capacitive discharge of the capacitor bank to the laser device during the time duration.