Abstract: A rotary fluid pressure device has a first oil passage with relatively high pressure fluid therein surrounding the gear set; a plurality of second oil passageways connecting the first oil passageway to the expanding and contracting oil chambers; and fluid non-return valves in each of the second oil passageways to permit the flow of oil therethrough only in a direction to the oil chambers from the first oil passageway to the oil chambers.

Abstract: The present invention relates to use of FVII and/or FVIIa and/or another TF agonist and/or FVIIai and/or another TF antagonist in therapeutic treatment of pathological conditions increased or decreased cell apoptosis is required.

Abstract: A valve member includes an axially movable spool valve rotatably mounted in the valve member to cause the way that fluid is communicated between the inlet and outlet ports of the device and the volume chambers thereof. An outer surface of the spool has a configuration to react to fluid pressure to effect the timing between the gear set and the valving of valve member and that the timing therebetween will be adjusted when the spool valve is moved axially. A valve actuator comprising a spring loaded plunger controlled by fluid pressure at the inlet and outlet ports is in physical contact with one end of the valve spool.

Abstract: Compositions comprising a TF antagonist and protein C or a protein C-related polypeptide, methods of using such compositions or active elements thereof for inducing, promoting and/or enhancing one or more physiological conditions in a subject (such as the prevention, amelioration, and/or other treatment of thrombotic or coagulopathic-related diseases, respiratory diseases, and/or inflammatory diseases), and additional related methods and compositions.

Abstract: The catalytic active site of Factor VII is modified to produce a compound which effectively interrupts the blood coagulation cascade. The modifications render Factor VIIa substantially unable to activate plasma Factors X or IX. The modified Factor VII may be used in conjunction with stents to inhibit coagulation, vascular restenosis, and/or platelet deposition.

Abstract: The invention described herein provides novel human Kunitz-type protease inhibitors; nucleic acids encoding such inhibitors; vectors and host cells comprising such nucleic acids; compositions comprising such inhibitors, cells, and/or nucleic acids; methods of producing such inhibitors, nucleic acids, vectors, compositions, and cells; and methods of inducing, promoting, and/or enhancing a physiological response in a subject by administering to the subject an amount of such an inhibitor, nucleic acid, vector, host cell, and/or composition sufficient to induce such a physiological response.

Abstract: Compositions comprising a tissue factor antagonist and a blood glucose regulator, methods of promoting, inducing, and/or enhancing a physiological response in a subject comprising administering such a composition or combination of tissue factor antagonist and blood glucose regulator, such as in the treatment or prevention of a thrombotic or coagulopathic disease, respiratory disease, or inflammatory disease.

Abstract: The catalytic active site of Factor VII is modified to produce a compound which effectively interrupts the blood coagulation cascade. The modifications render Factor VIIa substantially unable to activate plasma Factors X or IX. Pharmaceutical compositions of the modified Factor VII are used to treat a variety of coagulation-related disorders.

Abstract: This invention relates to novel compounds which bind to tissue factor and mediate a cytotoxic response.

Abstract: The invention concerns a tooth set for a hydraulic machine, particularly a steering unit, with a toothed ring, having teeth, which are formed by means of inserts arranged in a housing, and a gear wheel arranged inside the toothed ring. It is endeavoured to simplify the production of such a tooth set. For this purpose, each inset (10) has, at least at its ends, a plate-like shape and the ends are fixed in the housing (11) in corresponding slots (17, 18).

Abstract: The present invention relates to use of FVII and/or FVIIa and/or another TF agonist and/or FVIIai and/or another TF antagonist in therapeutic treatment of pathological conditions increased or decreased cell apoptosis is required.

Abstract: Damping arrangement for damping vibrations of cables or ropes, for vibration damping in carrier cables of bridges in particular, with at least one elastic element (5 to 8, 21) for reduction of vibration energy by elastic deformation, wherein said elastic element (5 to 8, 21) is arranged between a plurality of cables (17, 18, 19) to be dampened, in particular, however, between two cables (17, 18) or between said cable (1) to be dampened and a support element (9), as well as a carrier cable arrangement with at least one cable and at least one corresponding damping arrangement.

Abstract: The present invention relates to the use of a factor VIIa and a factor XIII in the treatment or prophylaxis of bleeding episodes.

Abstract: A novel intracellular signalling activity of coagulation factor VII (FVII) in cells expressing tissue factor (TF) is described. The present invention relates to use of FVIIa or another TF agonist, or FVIIai or another TF antagonist for the preparation of a medicament for modulation of FVIIa-induced activation of the MAPK signalling pathway in a patient. Moreover the present invention relates to a method of treatment, and a method of detecting the activity of compounds, in particular drug candidates, that interact with the FVIIa mediated intracellular signalling pathway.

Abstract: The invention concerns a tooth set for a hydraulic machine, particularly a steering unit, with a toothed ring, having teeth, which are formed by means of inserts arranged in a housing, and a gear wheel arranged inside the toothed ring. It is endeavoured to simplify the production of such a tooth set. For this purpose, each inset (10) has, at least at its ends, a plate-like shape and the ends are fixed in the housing (11) in corresponding slots (17, 18).

Abstract: The invention concerns a tooth set (1) for a hydraulic machine (2), particularly a hydraulic steering unit, with a toothed ring (3), a gear wheel (4) arranged inside the toothed ring (3), a first plate (7) on an axial front side of the gear wheel (4) and the toothed ring (3) and a second plate (5) on the other axial front side. A simplification of the production is endeavoured. For this purpose, the two plates (5, 7) and the parts between them, gear wheel (4) and toothed ring (3), can be handled as a self-retainingly assembled module (1).

Abstract: The present invention relates to use of FVII and/or FVIIa and/or another TF agonist and/or FVIIai and/or another TF antagonist in therapeutic treatment of pathological conditions that can be related to cell migration or treated by specific regulation of cell migration or chemotaxis. The invention also relates to the use of of FVII and/or FVIIa and/or another TF agonist and/or FVIIai and/or another TF antagonist in therapeutic treatment of pathological conditions that can be related to regulation of expression of at least one gene in a cell, e.g., Cyr61 gene.

Abstract: The present invention provides methods for modifying the motility of tissue factor (TF)-expressing cells, which are carried out by contacting such cells with an effective amount of Factor VIIai Factor VIIa agonist.

Abstract: The present invention provides methods for identifying candidate drugs that modulate factor VIIa-mediated intracellular signaling by measuring the effects of such drugs on the activation of the mitogen-activated protein kinase (MAP kinase) signaling pathway.

Abstract: The invention concerns a machine arrangement with a first machine having a first rotation connection, a second machine having a second rotation connection, and a shaft for transmission of a torque, the shaft being unrotatably connected with both rotation connections. In this connection it is desired to minimize the effects of alignment errors on mounting the two motors. For this purpose the shaft (5) has, at least in one end, an external toothing (6) engaging with an internal toothing (8, 9) of the machine at this end, said external toothing permitting a swivel movement of the shaft (5), the teeth (10) of said external toothing (6) having concavely extending tooth flanks (11, 12), whose axial ends (15, 16) are less curved than their area of the axial centre.