Abstract: An electromagnetic, EM, device, includes: a substrate having a dielectric layer and a first conductive layer at a first side of the substrate, the substrate having a via that extends at least partially through the substrate from the first side toward an opposing second side of the substrate; at least one dielectric structure having at least one non-gaseous dielectric material that forms a first dielectric portion that extends outward from the first side of the substrate, the first dielectric portion having a first average dielectric constant, the at least one dielectric structure further having a second dielectric portion that is contiguous with the first dielectric portion; wherein the second dielectric portion extends into the via of the substrate, the via having a mechanical interlock surface; and wherein the at least one dielectric structure includes a mechanical interlock between the second dielectric portion and the mechanical interlock surface of the via of the substrate.

Abstract: Techniques are described for managing communications between multiple intercommunicating computing nodes, such as multiple virtual machine nodes hosted on one or more physical computing machines or systems. In some situations, users may specify groups of computing nodes and optionally associated access policies for use in the managing of the communications for those groups, such as by specifying which source nodes are allowed to transmit data to particular destinations nodes. In addition, determinations of whether initiated data transmissions from source nodes to destination nodes are authorized may be dynamically negotiated for and recorded for later use in automatically authorizing future such data transmissions without negotiation. This abstract is provided to comply with rules requiring an abstract, and it is submitted with the intention that it will not be used to interpret or limit the scope or meaning of the claims.

Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.

Abstract: Ullage float assemblies for fuel tanks are disclosed including a guide member with a retaining element mounted to a valve body which includes a first valve port and a second valve port in fluid communication. Methods of preventing spillage of fuel from a fuel tank during a refueling and a diurnal fuel volumetric expansion event are also disclosed. The assemblies and methods.

Abstract: One aspect of the present invention relates to double-stranded RNA (dsRNA) agent capable of inhibiting the expression of a target gene. The antisense strand of the dsRNA molecule comprises at least one thermally destabilizing nucleotide occurring at a seed region; the dsRNA comprises at least four 2?-fluoro modifications, and the sense strand of the dsRNA molecule comprises ligand, wherein the ligand is an ASGPR ligand. Other aspects of the invention relates to pharmaceutical compositions comprising these dsRNA molecules suitable for therapeutic use, and methods of inhibiting the expression of a target gene by administering these dsRNA molecules, e.g., for the treatment of various disease conditions.

Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.

Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.

Abstract: The present method and system provides for network-based remote control racing, including receiving a user inputs accessing a gaming engine via user interfacing modules running on a mobile computing device. The method and system includes connecting the gaming engine with a vehicle control engine in response to the user inputs. Via the vehicle control engine, engaging remote control vehicles associated with separate users, wherein the remote control vehicles are physically disposed within a race course. The method and system generates vehicle control commands to control the remote-control vehicles based on the user inputs. Based thereon, the users physically race remote-control vehicles across a communication network. Included herewith, the gaming engine not only facilitates the racing, but distributes the racing content to the users, as well viewers actively watching the physical race.

Abstract: A method for determining the elevation angle and/or azimuth angle of a signal received by an ultrasound sensor includes: providing an ultrasound sensor with a frequency-dependent radiation pattern; transmitting a first ultrasound wave at a first frequency; transmitting a second ultrasound wave at a second frequency different from the first frequency; receiving reflections of the first and second waves, the reflections being caused by an object; and determining the elevation angle of the first and second reflected waves based on amplitudes of the reflections of the first and second waves. Determining the elevation angle (and/or azimuth angle includes calculating a ratio between the amplitudes of received reflections of the first and second waves and mapping a calculated ratio to an elevation angle and/or azimuth angle. The mapping is based on a predetermined ratio curve or ratio dataset which associates a certain amplitude ratio to an elevation angle and/or azimuth angle.

Abstract: In an embodiment, a printed circuit board substrate (12) comprises a polymer matrix; a reinforcing layer (42); and a plurality of coated boron nitride particles (44); wherein the plurality of coated boron nitride particles comprise a coating having an average coating thickness of 1 to 100 nanometers. The polymer matrix can comprise at least one of an epoxy, a polyphenylene ether, polystyrene, an ethylene-propylene dicyclopentadiene copolymer, a polybutadiene, a polyisoprene, a fluoropolymer, or a crosslinked matrix comprising at least one of triallyl cyanurate, triallyl isocyanurate, 1,2,4-trivinyl cyclohexane, trimethylolpropane triacrylate, or trimethylolpropane trimethacrylate.

Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.

Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. Move particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.

Abstract: A force absorbing device for a footwear appliance includes a shoe upper and a shoe sole having a planar sole surface, such that forces between the shoe upper and planar sole surface in ground contact are absorbed by force mitigation structures disposed in the shoe sole. A footwear article includes a split-sole system that redefines a shoe sole as coplanar surfaces having a force mitigating interface for receiving sudden forces and effectively mitigating these forces by storing kinetic energy and releasing it over time. An elastic field in the force mitigation structure is defined by a resilient material adapted to deform in response to the received force. Frictional engagement between the upper and lower sole may also be augmented by surface characteristics such as dimples, voids and lubricants, in addition to interference engagement with an elastic field.

Abstract: Described herein are methods, compositions, and systems derived from uncultivated microorganisms useful for gene editing.

Abstract: Methods and systems use a client application that resides on a client device (e.g., comprising private and secure access credentials). Using the client application, a user may authorize and/or accept a plurality of configuration files. Upon acceptance, the client application is capable of connecting to any interface predefined in the plurality of configuration files (e.g., corresponding to a predetermined list of network systems). The configuration files may be downloaded from a package repository or may be included during software installation.

Abstract: In an embodiment, a process to predict an outcome of a competition includes receiving time-stamped position information of participant(s), the time-stamped position information captured by a telemetry tracking system during the competition. The process includes calculating while the competition is ongoing a covariate parameter for each of one or more participants at a point in time, where each respective covariate parameter is derived from the time-stamped position information of a corresponding participant at the point in time. The process includes predicting the outcome of the competition, as of the point in time, based at least in part on (i) a difference between a calculated competitor strength of the first competitor the second competitor based on historical data associated with the competitors, and (ii) the calculated first covariate parameter(s).

Abstract: There is described a method for determining a play duration estimate of an adaptive bit rate (ABR) media presentation. The method comprises receiving at a network entity a media playlist manifest file of the media presentation, wherein the manifest file is transmitted from a content server to a client and comprises a plurality of entries, each entry linking to a respective different one of a plurality of media segments of the media presentation. The method further comprises determining a data size of the manifest file; and determining a play duration estimate of the media presentation based on the determined data size of the manifest file, a first value that represents a data size of each of the plurality of entries in the manifest file and a second value that represents a play duration of each media segment of the plurality of media segments of the media presentation.

Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.

Abstract: A process to track and provide positional information for display on a remote device includes receiving, on a first recurring basis, time-stamped position information of participant(s) in a competition. The time-stamped position information is captured by a telemetry tracking system during the competition and describes a time-stamped position of each of one or more corresponding participants in a predetermined spatial region. The process includes communicating at least a subset of time-stamped position information to the remote device on a second recurring basis. The remote device uses the time-stamped position information to overlay a representation of one or more of said participants onto a first virtual reproduction of at least a relevant portion of the predetermined spatial region to produce and display an instance of a compiled virtual scene that shows a respective position of each of the participant(s) on the first virtual reproduction of the predetermined spatial region.

Abstract: A geo-analytical program is integrated into a customer relationship management (CRM) solution. Via the geo-analytical program, users are able to define layer configuration settings for a layer for plotting on a map-based GUI. Layer configuration settings for a respective layer comprise an indication of a data object type serving as a base object type for the respective layer. A method involves receiving from a user user-defined configuration settings for a first layer, electronically receiving, at a geospatial computer system, geospatial data for a plurality of connected devices; electronically receiving, at the geo-analytical program from the geospatial computer system, real-time geospatial data for the plurality of connected devices; and utilizing, by the geo-analytical program, the user-defined layer configuration settings for the first layer to plot the first layer on the map-based GUI based on the received real-time geospatial data for the plurality of connected devices.