Patents by Inventor D. Horton

D. Horton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7919613
    Abstract: The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a SCAP gene (Human SCAP gene), comprising an antisense strand having a nucleotide sequence which is less that 30 nucleotides in length, generally 19-25 nucleotides in length, and which is substantially complementary to at least a part of a SCAP gene. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by Human SCAP expression and the expression of a SCAP gene using the pharmaceutical composition; and methods for inhibiting the expression of a SCAP gene in a cell.
    Type: Grant
    Filed: March 29, 2010
    Date of Patent: April 5, 2011
    Assignees: Alnylam Pharmaceuticals, Inc., Board of Regents, the Unversity of Texas System
    Inventors: Juergen Soutschek, Pamela Tan, Jay D. Horton, Michael S. Brown, Joseph L. Goldstein, Young-Ah Moon
  • Publication number: 20100324185
    Abstract: An unhindered polyol is used to react with an epoxidized soyate to make epoxidized soyate diester in the presence of a catalyst. The unhindered polyol can be 1,3-propanediol or any polyol having four or more carbon atoms with no two adjacent carbon atoms having hydroxyl functionality. Preferably, a combination of catalysts is used to promote the transesterification reaction of the epoxidized soyate with the unhindered polyol to yield a high percentage of epoxidized soyate diester with epoxy functionality retained. The primary catalyst is a metallic hydroxide, and the secondary catalyst is a titanate. Bioderived epoxidized soyate diester plasticizers useful for thermoplastics and thermosets result.
    Type: Application
    Filed: February 4, 2009
    Publication date: December 23, 2010
    Applicant: POLYONE CORPORATION
    Inventors: Kebin Geng, Roger W. Avakian, Louis Dupont, Stephen D. Horton
  • Publication number: 20100309935
    Abstract: A method and system of processing sampled voice packets from a voice packet sender for transmission over a bit-rate sampled data transmission system, such as by a cable modem over a cable modem termination system, to a voice packet recipient. Unsolicited grant arrivals in response to a request from the voice packet sender coupled to the cable modem are determined. The storing of sampled voice packets is synchronized with the unsolicited grant arrivals. Upon receipt of an unsolicited grant arrival, currently stored sampled voice packets are transmitted to the cable modem for further transmission to the voice packet recipient over the cable modem termination system.
    Type: Application
    Filed: August 16, 2010
    Publication date: December 9, 2010
    Applicant: Broadcom Corporation
    Inventors: Theodore F. Rabenko, James C.H. Thi, John D. Horton, JR.
  • Publication number: 20100276652
    Abstract: A livestock guard. The livestock guard may include a rectangular base frame. Two vertical posts may be attached to the rectangular base frame. There may be a pivot bar centrally and longitudinally oriented within the rectangular base frame. There may be two livestock guard ramps within the rectangular base frame and pivotally attached to the pivot bar in such a way as to decline away from the pivot bar in opposite directions. The pivot bar may be supported at each end by a spring assembly housed in one of the vertical post members. The pivot bar may be supported in such a way as to normally rest at a predetermined height above the rectangular base frame and also in such a way as to be depressible to the height of the rectangular base frame when pressed under a certain weight.
    Type: Application
    Filed: April 29, 2009
    Publication date: November 4, 2010
    Inventor: Travis D. Horton
  • Publication number: 20100267875
    Abstract: A non-halogenated elastomeric latex is disclosed, using as flame retardants, an aqueous dispersion of organoclay and a conventional non-halogenated flame retardant, of which less is needed than conventionally, because of the use of the organoclay. The latex can become a film, sheet, or other article.
    Type: Application
    Filed: November 21, 2008
    Publication date: October 21, 2010
    Applicant: POLYONE CORPORATION
    Inventor: Stephen D. Horton
  • Patent number: 7801176
    Abstract: A method and system of processing sampled voice packets from a voice packet sender for transmission over a bit-rate sampled data transmission system, such as by a cable modem over a cable modem termination system, to a voice packet recipient. Unsolicited grant arrivals in response to a request from the voice packet sender coupled to the cable modem are determined. The storing of sampled voice packets is synchronized with the unsolicited grant arrivals. Upon receipt of an unsolicited grant arrival, currently stored sampled voice packets are transmitted to the cable modem for further transmission to the voice packet recipient over the cable modem termination system.
    Type: Grant
    Filed: October 21, 2005
    Date of Patent: September 21, 2010
    Assignee: Broadcom Corporation
    Inventors: Theodore F. Rabenko, James C. H. Thi, John D. Horton, Jr.
  • Patent number: 7794626
    Abstract: A cathodic protection compound is disclosed. The coating includes sacrificial metallic particles less noble than metal in the metal substrate to be protected. The coating also includes inherently conductive polymer in an amount of less than 1 weight percent of total solids of the coating. A concentrate of the metallic particles and inherently conductive polymer can also be prepared.
    Type: Grant
    Filed: February 1, 2005
    Date of Patent: September 14, 2010
    Assignee: PolyOne Corporation
    Inventor: Stephen D. Horton
  • Publication number: 20100184829
    Abstract: The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a SCAP gene (Human SCAP gene), comprising an antisense strand having a nucleotide sequence which is less that 30 nucleotides in length, generally 19-25 nucleotides in length, and which is substantially complementary to at least a part of a SCAP gene. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by Human SCAP expression and the expression of a SCAP gene using the pharmaceutical composition; and methods for inhibiting the expression of a SCAP gene in a cell.
    Type: Application
    Filed: March 29, 2010
    Publication date: July 22, 2010
    Inventors: Juergen Soutschek, Pamela Tan, Jay D. Horton, Michael S. Brown, Joseph L. Goldstein, Young-Ah Moon
  • Patent number: 7737266
    Abstract: The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a SCAP gene (Human SCAP gene), comprising an antisense strand having a nucleotide sequence which is less that 30 nucleotides in length, generally 19-25 nucleotides in length, and which is substantially complementary to at least a part of a SCAP gene. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by Human SCAP expression and the expression of a SCAP gene using the pharmaceutical composition; and methods for inhibiting the expression of a SCAP gene in a cell.
    Type: Grant
    Filed: September 18, 2007
    Date of Patent: June 15, 2010
    Assignees: Board of Regents, The University of Texas System, Alnylam Pharmaceuticals, Inc.
    Inventors: Juergen Soutschek, Pamela Tan, Jay D. Horton, Michael S. Brown, Joseph L. Goldstein, Young-Ah Moon
  • Publication number: 20100135329
    Abstract: Data packets transmitted over a wireless network are suppressed by hardware at the transmitting end and expanded on the receiving end. This conserves bandwidth as well as reduces the processing resource requirements in both the subscriber station and the base station. An extended header element is added to a data packet that is to be transmitted over the wireless network. The extended header element contains an index that is used along with an identifier to access a rule. The rule is used to determine which bytes are to be suppressed at the transmitter and expanded at the receiver.
    Type: Application
    Filed: January 29, 2010
    Publication date: June 3, 2010
    Applicant: Broadcom Corporation
    Inventors: John D. HORTON, JR., Robert J. Lee, David M. Pullen
  • Patent number: 7710960
    Abstract: Data packets transmitted over a wireless network are suppressed by hardware at the transmitting end and expanded on the receiving end. This conserves bandwidth as well as reduces the processing resource requirements in both the subscriber station and the base station. An extended header element is added to a data packet that is to be transmitted over the wireless network. The extended header element contains an index that is used along with an identifier to access a rule. The rule is used to determine which bytes are to be suppressed at the transmitter and expanded at the receiver.
    Type: Grant
    Filed: March 21, 2007
    Date of Patent: May 4, 2010
    Assignee: Broadcom Corporation
    Inventors: John D. Horton, Jr., Robert J. Lee, David M. Pullen
  • Patent number: 7688826
    Abstract: Data packets transmitted over a wireless network are suppressed by hardware at the transmitting end and expanded on the receiving end. This conserves bandwidth as well as reduces the processing resource requirements in both the subscriber station and the base station. An extended header element is added to a data packet that is to be transmitted over the wireless network. The extended header element contains an index that is used along with an identifier to access a rule. The rule is used to determine which bytes are to be suppressed at the transmitter and expanded at the receiver.
    Type: Grant
    Filed: March 21, 2007
    Date of Patent: March 30, 2010
    Assignee: Broadcom Corporation
    Inventors: John D. Horton, Jr., Robert J. Lee, David M. Pullen
  • Patent number: 7670511
    Abstract: A cathodic protection coating is disclosed that unexpectedly protects a treated metal substrate, notwithstanding the presence of a phosphate-containing conversion coating between the metal substrate and the cathodic protection compound. The cathodic protection coating includes sacrificial metallic particles less noble than metal in the metal substrate to be protected. The coating also includes inherently conductive polymer.
    Type: Grant
    Filed: September 22, 2005
    Date of Patent: March 2, 2010
    Assignee: PolyOne Corporation
    Inventor: Stephen D. Horton
  • Patent number: 7621074
    Abstract: A novel tackle box is disclosed which employs hook attaching means comprising a vertical slot adapted to receive the hooks of artificial fishing bait. The hook attaching means are secured to the top inside of the tackle box or to one or more horizontal shelves in said box so that any bait stored is suspended during storage. Suspension allows for drying of the tackle and prevention of rust. The tackle may be easily inserted and easily removed from the slots. The box provides an effective storage means and method especially for unwieldy and cumbersome baits.
    Type: Grant
    Filed: July 22, 2005
    Date of Patent: November 24, 2009
    Inventors: Darrell L. Glidewell, Billy D. Horton, Jr.
  • Publication number: 20090275053
    Abstract: The present invention includes a PCSK9 activity inhibition assay system, kits, compositions and methods. The present invention includes a cell having a first vector capable of expressing a catalytic fragment of PCSK9, a second vector capable of expressing a prodomain of PCSK9 and a V5 protein with a detectable label. The V5 protein forms a fusion protein with the prodomain of PCSK9 and wherein cleavage of the prodomain by the catalytic fragment of PCSK9 releases a detectable signal.
    Type: Application
    Filed: April 30, 2008
    Publication date: November 5, 2009
    Applicant: Board of Regents, The University of Texas System
    Inventors: Jay D. Horton, Markey C. McNutt
  • Patent number: 7604753
    Abstract: A mixture of inherently conductive polymer and plastisol is disclosed. Articles made from the mixture can be used as electrostatic dissipative (ESD) articles.
    Type: Grant
    Filed: November 10, 2004
    Date of Patent: October 20, 2009
    Assignee: Polyone Corporation
    Inventor: Stephen D. Horton
  • Publication number: 20090093426
    Abstract: The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a SCAP gene (Human SCAP gene), comprising an antisense strand having a nucleotide sequence which is less that 30 nucleotides in length, generally 19-25 nucleotides in length, and which is substantially complementary to at least a part of a SCAP gene. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by Human SCAP expression and the expression of a SCAP gene using the pharmaceutical composition; and methods for inhibiting the expression of a SCAP gene in a cell.
    Type: Application
    Filed: September 18, 2007
    Publication date: April 9, 2009
    Inventors: Juergen Soutschek, Pamela Tan, Jay D. Horton, Michael S. Brown, Joseph L. Goldstein, Young-Ah Moon
  • Publication number: 20090092153
    Abstract: Downstream synchronous multichannel (DSSM) communications are provided among a plurality of carriers, each being a completely DOCSIS™ 2.0-compliant downstream. The synchronous multichannels support communications with both DSSM-capable communications nodes and non-DSSM-capable communications nodes (e.g., legacy cable modems). Non-DSSM packets are transmitted on a single channel. DSSM packets are split into multiple pieces, which are transmitted simultaneously on all available channels. Since the physical delay variation (e.g., group delay change) across the adjacent carriers is small (on the order of a symbol time), the multiple pieces arrive at the receiving communications nodes at nearly the same time and can be reassembled with minimal buffering and no packet ordering problems. To avoid causing trouble for the non-DSSM-capable communications nodes, the packet pieces are encapsulated with a header that causes the non-DSSM-capable communications nodes to silently discard them.
    Type: Application
    Filed: October 27, 2008
    Publication date: April 9, 2009
    Applicant: Broadcom Corporation
    Inventors: Daniel H. HOWARD, Niki R. Pantelias, David M. Pullen, John D. Horton, JR., Thomas J. Quigley, Richard S. Prodan
  • Patent number: 7450579
    Abstract: Downstream synchronous multichannel (DSSM) communications are provided among a plurality of carriers, each being a completely DOCSIS™ 2.0-compliant downstream. The synchronous multichannels support communications with both DSSM-capable communications nodes and non-DSSM-capable communications nodes (e.g., legacy cable modems). Non-DSSM packets are transmitted on a single channel. DSSM packets are split into multiple pieces, which are transmitted simultaneously on all available channels. Since the physical delay variation (e.g., group delay change) across the adjacent carriers is small (on the order of a symbol time), the multiple pieces arrive at the receiving communications nodes at nearly the same time and can be reassembled with minimal buffering and no packet ordering problems. To avoid causing trouble for the non-DSSM-capable communications nodes, the packet pieces are encapsulated with a header that causes the non-DSSM-capable communications nodes to silently discard them.
    Type: Grant
    Filed: September 9, 2004
    Date of Patent: November 11, 2008
    Assignee: Broadcom Corporation
    Inventors: Daniel H. Howard, Niki R. Pantelias, David M. Pullen, John D. Horton, Jr., Tom Quigley, Richard S. Prodan
  • Publication number: 20080265217
    Abstract: A cathodic protection compound is disclosed. The coating includes sacrificial metallic particles less noble than metal in the metal substrate to be protected. The coating also includes inherently conductive polymer in an amount of less than 1 weight percent of total solids of the coating. A concentrate of the metallic particles and inherently conductive polymer can also be prepared.
    Type: Application
    Filed: February 1, 2005
    Publication date: October 30, 2008
    Applicant: POLYONE CORPORATION
    Inventor: Stephen D. Horton