Abstract: The present invention relates to agents capable of binding sialic acid-binding immunoglobulin-like lectin-9 (Siglec-9) and their use in the treatment of cell proliferation and differentiation disorders. Furthermore, the present invention provides associated pharmaceutical formulations and methods.

Abstract: An overshoe that covers a footwear structure for protecting a walking surface. The overshoe includes a base and an upstanding portion, which extends around at least a portion of the base. A protrusion extends inwardly from an inner surface of the upstanding portion. The protrusion engages the footwear structure for releasably retaining the overshoe to the footwear structure.

Abstract: The invention features an electrical connection apparatus capable of operatively attaching to an electrical appliance or electrical socket. The apparatus also includes at least two electrical connections which can communicate with each other to allow the flow of electrical charge therebetween. The apparatus can also be arranged to allow relative movement of the at least first and/or second electrical connection between a first position, wherein electrical charge can flow therebetween, and a second position, wherein the flow of electrical charge is prevented. The relative movement can take place over a pre-determined time period following actuation to provide a timing mechanism for the apparatus.

Abstract: The invention relates to a timing device for use with a cable, and also to a cable including said timing device. The device is formed so as to be movable between a first position in which electricity is prevented from flowing therethrough and a second position in which electricity can flow therethrough. When in the second position, the cable with which the device is provided, and apparatus connected to the cable is rendered electrically operable. The device is provided to allow electrical connection for a predetermined time period, such that at the end of the said time period, the device has moved back to the first position. The provision of the device as part of the cable allows the same to be positioned in a room for easier user access and hence user operation.

Abstract: An electrical adaptor (100) is provided including first electrical connection means (116) for allowing electrical connection of the adaptor with an electrical socket (148) and/or electrical supply in use, at least second electrical connection means for allowing electrical connection of an electrical plug or further electrical connection with the adaptor, and timing means for electrical current to be supplied through said adaptor in use for one or more pre-determined time periods. The timing means includes at least first (102) and second (136) parts which are capable of undergoing relative movement in use between a first position, wherein electrical current can flow through said adaptor between the first and at least second electrical connection means, and a second position, wherein electrical current is prevented from flowing through the adaptor between the first and at least second electrical connection means.

Abstract: The present invention relates to agents capable of binding sialic acid-binding immunoglobulin-like lectin-9 (Siglec-9) and their use in the treatment of cell proliferation and differentiation disorders. Furthermore, the present invention provides associated pharmaceutical formulations and methods.

Abstract: An electrical wall socket is provided including a housing having one or more electrical socket connection means defined thereon to allow engagement with at least one electrical plug therewith in use. The wall socket is provided with timing means for timing or determining one or more pre-determined time periods. The timing means are arranged such that when actuated, the timing means allow electrical current to flow through said electrical socket from an electrical supply and/or from said electrical socket connection means to an electrical plug engaged therewith in use for said one or more pre-determined time periods.

Abstract: A containment device including a cover defining an internal volume and an opening into the internal volume, the cover being formed as a layered structure including at least a first layer and a second layer, the first layer comprising a woven ceramic fabric and the second layer comprising oxidized polyacrylonitrile fibers.

Abstract: Dispensing apparatus (16) is provided including a housing (18) having at least first and second fluid outlet means (30,32) to allow fluid to flow out of said dispensing apparatus. Channel means (23) are provided in the housing (18) least one aperture defined therein to allow fluid to flow from said channel means (23) through either of said at least first fluid outlet means (30, 32). The apparatus further includes fluid flow control means (104) for allowing selective control of the fluid flow from said channel means through said at least first or second fluid outlet means (30, 32). The fluid flow control means (104) includes a closure element (104) having passage means defined therein.

Abstract: A coating and associated method for coating is disclosed. The coating provides a hard, transparent, UV blocking coating for a substrate. A UV blocking layer is first deposited upon the substrate, and a hard coating is deposited above the UV blocking layer. A soft coating layer may be deposited between the UV blocking layer and the hard coating. The soft and hard coating layers may both have the general composition SiOxCy. the soft and hard coating layers may be deposited by a plasma vapor deposition process.

Abstract: A hard, transparent coating for a substrate and associated method for coating is disclosed. The coating includes alternating layers of a soft coating and a hard coating. The coating further includes a sensor. The electrical resistivity of the sensor may be measured to determine if the coating has been degraded. The coating may further include a hydrophobic outer layer.

Abstract: An inertial measurement unit comprises a mounting plate with an opening therethrough, and a sensor assembly disposed in the opening of the mounting plate. Upper and lower support shells having shell flanges are attached to upper and lower surfaces of the mounting plate. The upper and lower support shells surround the sensor assembly. A plurality of gas bearing pads each extends through apertures in the upper and lower support shells. Upper and lower gas plenums have plenum flanges attached to the shell flanges of the upper and lower support shells, with the upper and lower gas plenums surrounding the upper and lower support shells. Pressure relief valves are coupled to the plenum flanges of the upper and lower gas plenums. The gas bearing pads and the sensor assembly are separated by a gap when pressurized gas is fed into the upper and lower gas plenums, thereby creating a gas bearing that allows the sensor assembly to be freely suspended and rotated in all directions.

Abstract: Toilet cleaning apparatus is provided including dispensing means for dispensing fluid therefrom for cleaning the toilet and connection means for connecting the dispensing means to a fluid supply for providing a source of fluid to the dispensing means in use. The dispensing means includes a housing having fluid inlet means and fluid outlet means. The housing includes two or more parts and the parts are rotatably mounted to each other in use.

Abstract: An inertial measurement unit comprises a mounting plate with an opening therethrough, and a sensor assembly disposed in the opening of the mounting plate. Upper and lower support shells having shell flanges are attached to upper and lower surfaces of the mounting plate. The upper and lower support shells surround the sensor assembly. A plurality of gas bearing pads each extends through apertures in the upper and lower support shells. Upper and lower gas plenums have plenum flanges attached to the shell flanges of the upper and lower support shells, with the upper and lower gas plenums surrounding the upper and lower support shells. Pressure relief valves are coupled to the plenum flanges of the upper and lower gas plenums. The gas bearing pads and the sensor assembly are separated by a gap when pressurized gas is fed into the upper and lower gas plenums, thereby creating a gas bearing that allows the sensor assembly to be freely suspended and rotated in all directions.

Abstract: Electrical connection apparatus is provided including engagement means to allow attachment of the apparatus to an electrical appliance or electrical socket in use and at least first and second electrical connection means which can communicate with each other in use to allow the flow of electrical charge therebetween. The apparatus further includes movement means arranged to allow relative movement of the at least first and/or second electrical connection means between a first position, wherein electrical charge can flow therebetween, and a second position, wherein the flow of electrical charge is prevented. The relative movement takes place over a pre-determined time period following actuation or on actuation of said movement means to provide a timing mechanism for the apparatus.

Abstract: Octagonal container assemblies to package and display of products, particularly toys with moving wheels, appendages or the like to demonstrate movement of the same in the container, include a tubular body and at least two octagonal end covers removable or at least pivotal away from opposing ends of the tubular body. The container assemblies include a beam extended between the end covers and a rigid support member extended transversely from the beam so as to support the toy for at least limited operation or the wheels or the like within the container. The beam may be inserted in the container or extend along its exterior.

Abstract: A receptacle terminal includes a cable connection portion 31 connected to a cable, and a contacting portion 2 insertion-connected to a tab terminal. The contacting portion 2 has a flat part 21 of a particular area, and a pair of sideplate parts 23, 23 of a particular length that stand up in the same direction from the two sides of the flat part and oppose each other at a particular spacing. The lower portion of the opposed surfaces of such pair of sideplate parts 23, 23 is cut and lifted out to form spring pieces 24, 24 which remains joined to the sideplate at the top. Such spring pieces are bent toward each other, forming a gap between the bottom edge of each spring piece and the flat part, and the tab terminal 4 is inserted into such gaps. A simple structure and strong elastic contacting force are provided.

Abstract: An overshoe that covers a footwear structure for protecting a walking surface. The overshoe includes a base and an upstanding portion, which extends around at least a portion of the base. A protrusion extends inwardly from an inner surface of the upstanding portion. The protrusion engages the footwear structure for releasably retaining the overshoe to the footwear structure.

Abstract: An inertial measurement unit comprises an outer case assembly including an upper gas plenum and a lower gas plenum, with upper and lower support shells surrounded by the upper and lower gas plenums. A sensor assembly includes a sensor shell, with the sensor assembly surrounded by the upper and lower support shells. A plurality of gas bearing pads extend through apertures in the upper and lower support shells and are configured to inject a first pressurized gas into a gap that separates the gas bearing pads and the sensor shell. A wireless power transfer transformer includes a power transmitting core mounted to the outer case assembly, and a power receiving core mounted in an opening of the sensor shell. The receiving core is configured to be aligned with the transmitting core for wireless power transfer. The transmitting core is configured to inject a second pressurized gas into a gap between the transmitting core and the receiving core.