Abstract: A cover device kit includes: a plurality of heat insulation components comprising a lightweight construction material such as synthetic resin foam capable of being transported in a disassembled state and then quickly assembled into a box-shaped heat barrier structure having six sides including an opening on an open side for covering an opening in a floor or wall of a building. Four of the plurality of heat insulation components 14, 16, 18, 20 each includes two complimentary connections for uniting with two corresponding adjacent heat insulation components of the plurality of heat insulation components when assembled into four side walls of the box-shaped heat barrier structure 10. The cover 12 serves as a fifth heat insulation component and unites with the four components 14, 16, 18, 20 that constitute side walls of the box-shaped structure and is situated opposite the opening on the open side.

Abstract: The present invention is directed compositions for delivery of RNA interference (RNAi) polynucleotides to cells in vivo. The compositions comprise amphipathic membrane active polyamines reversibly modified with enzyme cleavable dipeptide-amidobenzyl-carbonate masking agents. Modification masks membrane activity of the polymer while reversibility provides physiological responsiveness. The reversibly modified polyamines (dynamic polyconjugate or DPC) are further covalently linked to an RNAi polynucleotide or co-administered with a targeted RNAi polynucleotide-targeting molecule conjugate.

Abstract: A coolant box for a glass batch charger that includes a base, a front wall, a rear wall, a coolant labyrinth extending from the base between the front and rear walls, and including a plurality of curvate baffle walls establishing a plurality of curvate coolant channels.

Abstract: The claimed subject matter relates to architectures and/or mechanisms that can facilitate issuing, embedding and verification of an optical DNA (o-DNA) signature. A first mechanism is provided for obtaining a set of manufacturing errors inherent in an optical media instance. These errors can be encoded into the o-DNA that can be cryptographically signed with a private key, then embedded into the source optical media instance. A second mechanism is provided that can decrypt the o-DNA with a public key and compare the authenticated errors to the observed errors to ascertain whether the optical media instance is authentic as opposed to a forgery or counterfeit.

Abstract: A thermal barrier is formed into a hat-shape by folding sections of an extended length of board formed for assembly and insertion as a barrier to thermal radiation into a space between two joists or studs of a floor, wall, roof, or ceiling of a building for completely covering the space while also covering protruding edges of the joists or studs so as to reduce thermal energy transfer through the joists or studs themselves. A thermal barrier assembly is shown with an outer reflective surface and is also shown for assembly into a form having an inner enclosure for enclosing an inner thermal barrier also having a reflective surface for reducing thermal radiation transfer by reflection and protected from dust by virtue of the enclosure.

Abstract: The invention provides use of novel compounds for delivery of nucleic acids, and conjugates of these compounds with nucleic acids. Further novel design criteria for chemically stabilized siRNA particular useful when covalently attached to said compounds and co-administered with a delivery polymer to achieve mRNA knock down in vivo are disclosed therein.

Abstract: The invention provides novel compounds and conjugates of these compounds useful for the delivery of biologically active substances. Further novel design criteria for chemically stabilized siRNA particular useful when covalently attached to a delivery polymer to achieve in vivo mRNA knock down are disclosed therein.

Abstract: An energy barrier is made of adjustable width insulating rails, reflective insulation panels and a gasketing element to create a single layer or multi-layer stack of reflective dead air spaces within cavity spaces of framing members of a building envelope where an efficient energy barrier is desired.

Abstract: The present invention is directed to compounds, compositions, and methods useful for delivering polynucleotides or other cell-impermeable molecules to mammalian cells. Described are polyconjugates systems that incorporate targeting, anti-opsonization, anti-aggregation, and transfection activities into small biocompatible in vivo delivery vehicles. The use of multiple reversible or labile linkages connecting component parts provides for physiologically responsive activity modulation.

Abstract: A coolant box for a glass batch charger that includes a base, a front wall, a rear wall, a coolant labyrinth extending from the base between the front and rear walls, and including a plurality of curvate baffle walls establishing a plurality of curvate coolant channels.

Abstract: A neck ring for molding a glass container neck finish that includes at least one closure attachment feature. The neck ring includes two semi-annular bi-metal neck ring halves, each consisting essentially of a neck ring insert of wear-resistant metal construction, and a neck ring body of heat-conductive metal construction different from said wear-resistant metal construction and formed around said neck ring insert so as to embed it in said neck ring body. Each of said neck ring halves has a glass-contacting cavity face that includes a first surface portion formed by said inserts for molding the at least one closure attachment feature on the neck finish, and a second surface portion formed by said bodies for molding portions of the neck finish excluding the at least one closure attachment feature.

Abstract: A coolant box for a glass batch charger that includes a base, a front wall, a rear wall, a coolant labyrinth extending from the base between the front and rear walls, and including a plurality of curvate baffle walls establishing a plurality of curvate coolant channels.

Abstract: The present invention is directed compositions for targeted delivery of RNA interference (RNAi) polynucleotides to hepatocytes in vivo. Targeted RNAi polynucleotides are administered together with co-targeted melittin delivery peptides. Delivery peptides provide membrane penetration function for movement of the RNAi polynucleotides from outside the cell to inside the cell. Reversible modification provides physiological responsiveness to the delivery peptides.

Abstract: The present invention is directed compositions for targeted delivery of RNA interference (RNAi) polynucleotides to hepatocytes in vivo. Targeted RNAi polynucleotides are administered together with co-targeted delivery polymers. Delivery polymers provide membrane penetration function for movement of the RNAi polynucleotides from outside the cell to inside the cell. Reversible modification provides physiological responsiveness to the delivery polymers.

Abstract: The present invention is directed compositions for targeted delivery of RNA interference (RNAi) polynucleotides to hepatocytes in vivo. Targeted RNAi polynucleotides are administered together with co-targeted melittin delivery peptides. Delivery peptides provide membrane penetration function for movement of the RNAi polynucleotides from outside the cell to inside the cell. Reversible modification provides physiological responsiveness to the delivery peptides.

Abstract: A coolant box for a glass batch charger that includes a base, a front wall, a rear wall, a coolant labyrinth extending from the base between the front and rear walls, and including a plurality of curvate baffle walls establishing a plurality of curvate coolant channels.

Abstract: An insulating panel to be used in a panelized insulation system for insulating and finishing walls, including basement walls has a foam core made of inorganic materials. The system incorporates a capillary break, an integrated water drainage system and an electrical wire chase system within an insulating wall panel. Vertical slots are provided for insertion of metal studs for use in attaching the interior finish panel, such as inorganic fiber cement board with a vinyl laminate finish, onto the insulating panels. Embedding metal studs in the panel core reduces the sound transmission though the panel and eliminates thermal bridging between warm and cold surfaces. Steps on the edges and the top/bottom surfaces of the insulating panel allow more panels to join together with shiplap joints.

Abstract: The present invention is directed compositions for delivery of RNA interference (RNAi) polynucleotides to cells in vivo. The compositions comprise amphipathic membrane active polyamines reversibly modified with enzyme cleavable dipeptide-amidobenzyl-carbonate masking agents. Modification masks membrane activity of the polymer while reversibility provides physiological responsiveness. The reversibly modified polyamines (dynamic polyconjugate or DPC) are further covalently linked to an RNAi polynucleotide or co-administered with a targeted RNAi polynucleotide-targeting molecule conjugate.

Abstract: The present invention is directed compositions for targeted delivery of RNA interference (RNAi) polynucleotides to hepatocytes in vivo. Targeted RNAi polynucleotides are administered together with co-targeted delivery polymers. Delivery polymers provide membrane penetration function for movement of the RNAi polynucleotides from outside the cell to inside the cell. Reversible modification provides physiological responsiveness to the delivery polymers.

Abstract: The present invention is directed to compounds, compositions, and methods useful for delivering polynucleotides or other cell-impermeable molecules to mammalian cells. Described are polyconjugates systems that incorporate targeting, anti-opsonization, anti-aggregation, and transfection activities into small biocompatible in vivo delivery vehicles. The use of multiple reversible or labile linkages connecting component parts provides for physiologically responsive activity modulation.