Abstract: The disclosure is directed to: (a) phosphacycle ligands; (b) catalyst compositions comprising phosphacycle ligands; and (c) methods of using such phosphacycle ligands and catalyst compositions in bond forming reactions.

Abstract: This disclosure is directed to: (a) processes for preparing compounds and salts thereof that, inter alia, are useful for inhibiting hepatitis C virus (HCV); (b) intermediates useful for the preparation of the compounds and salts; (c) pharmaceutical compositions comprising the compounds or salts; and (d) methods of use of such compositions.

Abstract: The disclosure is directed to: (a) phosphacycle ligands; (b) catalyst compositions comprising phosphacycle ligands; and (c) methods of using such phosphacycle ligands and catalyst compositions in bond forming reactions.

Abstract: An engine system that includes a timing drive cavity defined by at least one of an engine block, front cover, and timing drive cover, a timing drive positioned within the timing drive cavity, and a fluid pump assembly. The fluid pump assembly includes an impeller housing, a fluid inlet port coupled to the impeller housing, and a fluid outlet port coupled to the impeller housing. At least one of the fluid inlet and fluid outlet ports is positioned at least partially within the timing drive cavity.

Abstract: The disclosure is directed to: (a) phosphacycle ligands; (b) methods of using such phosphacycle ligands in bond forming reactions; and (c) methods of preparing phosphacycle ligands.

Abstract: This disclosure is directed to: (a) processes for preparing compounds and salts thereof that, inter alia, are useful for inhibiting hepatitis C virus (HCV); (b) intermediates useful for the preparation of the compounds and salts; (c) pharmaceutical compositions comprising the compounds or salts; and (d) methods of use of such compositions.

Abstract: A variable valve timing system and methods of operation are provided. A primary valve train driver is configured to rotate about a primary axis. A primary camshaft includes a first plurality of cams positioned on the primary camshaft. The primary camshaft is coaxially coupled to the primary valve train driver. The first plurality of cams is configured to rotate about the primary axis. A primary camshaft phaser is coaxially coupled to the primary camshaft. The primary camshaft phaser is rotatably coupled to the primary valve train driver so as to rotate the primary camshaft phaser and the primary camshaft to a first phase angle. A secondary camshaft driver on the primary axis is coaxially coupled to the primary camshaft, and a secondary camshaft phaser is coaxially coupled to the primary camshaft and coupled to the secondary camshaft driver on the primary axis.

Abstract: A variable valve actuation system in one form includes a rocker coupled with a valve stem at one end and a cam follower at the other end. The rocker is operable to rotate about a fixed axis and the cam follower includes a set of lower rollers operable to follow one cam lobe and an upper roller operable to follow another cam lobe. A leaf spring can be used to couple the cam follower with the rocker. A cam shaft can have a nested configuration that includes an inner shaft, an intermediate tube, and an outer tube. Cam lobes can be fastened to the cam shaft by fastening through each of the inner shaft, intermediate tube, and outer tube. The cam lobes can be attached by at least two devices inserted from either side of the cam shaft and that are not inserted at least through the inner shaft.

Abstract: Engine lubrication systems and methods of manufacturing and implementing engine lubrication systems and methods. In particular embodiments, an engine system includes an internal combustion engine lubrication system that utilizes a stacked configuration of a through-bolted engine to pattern around through-bolts and utilizes substantially hollow bulkheads to define a central high-pressure lubrication reservoir that minimizes lube system pressure while maintaining pressure at the extremities of the lubrication circuit. Available space is utilized within the bulkheads to provide a lubrication drainage restriction for reducing lubrication losses at engine shut-down.

Abstract: An internal combustion engine and related components and methods of manufacturing and implementing an internal combustion engine and related components. The internal combustion engine includes a base, a cylinder block mounted onto the base, a cylinder head mounted onto the block, and a structural overhead member mounted onto the cylinder head, such that the cylinder head is positioned between the cylinder block and the structural overhead member. At least one through-bolt positioned in a through-bolt opening, the through-bolt opening extending from the base to the structural overhead member through the cylinder block and the cylinder head to couple the base, the cylinder block, the cylinder head and the structural overhead member together.

Abstract: A nutating balance device for mitigating vibrations of an internal combustion engine having a crankshaft includes a coupler coupled to the engine crankshaft. The device also includes a weight coupled to the coupler. The coupler is configured to move the weight in sync with the crankshaft. The nutating balance device can generate variable torque pulsations or moments corresponding to torque harmonic frequencies of the internal combustion engine.

Abstract: The disclosure is directed to: (a) phosphacycle ligands; (b) catalyst compositions comprising phosphacycle ligands; and (c) methods of using such phosphacycle ligands and catalyst compositions in bond forming reactions.

Abstract: The disclosure is directed to: (a) phosphacycle ligands; (b) catalyst compositions comprising phosphacycle ligands; and (c) methods of using such phosphacycle ligands and catalyst compositions in bond forming reactions.

Abstract: A diesel engine includes a cylinder block having a cylinder cavity defined therein. A cylinder head is coupled to the cylinder block and includes a lower semi-hemispherical surface defined thereon that defines an upper boundary of a combustion chamber. The engine includes a piston slideably disposed within the cylinder cavity that includes a piston crown having an upper surface configured to define a first portion of a lower boundary of the combustion chamber. The upper surface of the piston crown includes an axi-symmetric semi-hemispherical shape configured to correspond to the lower semi-hemispherical surface of the cylinder head.

Abstract: One embodiment is a unique vehicle having a hybrid drive system. Other embodiments include unique hybrid drive systems. Still other embodiments include apparatuses, systems, devices, hardware, methods, and combinations for fluid driven actuation systems. Further embodiments, forms, features, aspects, benefits, and advantages of the present application shall become apparent from the description and figures provided herewith.

Abstract: A crystalline form of a drug, ways to make it, compositions containing it and methods of treatment of diseases and inhibition of adverse physiological events using it are disclosed.

Abstract: This disclosure is directed to: (a) processes for preparing compounds and salts thereof that, inter alia, are useful for inhibiting hepatitis C virus (HCV); (b) intermediates useful for the preparation of the compounds and salts; (c) pharmaceutical compositions comprising the compounds or salts; and (d) methods of use of such compositions.

Abstract: Rib configurations for increasing the structural efficiency of a cylinder head, which relates to a peak combustion pressure capability of the cylinder head. In addition to increasing peak combustion pressure, the rib configurations may also improve sealing of the cylinder head and may improve the durability of an associated cylinder head gasket.

Abstract: The disclosure is directed to: (a) phosphacycle ligands; (b) catalyst compositions comprising phosphacycle ligands; and (c) methods of using such phosphacycle ligands and catalyst compositions in bond forming reactions.

Abstract: A process for making 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid, and therapeutically acceptable salts thereof, and intermediates used in the process are disclosed.