Abstract: Protective over garment shorts including at least one pocket sized and otherwise dimensioned to removeably receive a ballistic protection panel therein and at least one ballistic protection panel configured to fit within each of the at least one pockets. The shorts are configured to be worn over existing pants and extend from a position covering the pelvic region of a wearer to a position proximate the knee region of the wearer.

Abstract: Protective over garment shorts including at least one pocket sized and otherwise dimensioned to removeably receive a ballistic protection panel therein and at least one ballistic protection panel configured to fit within each of the at least one pockets. The shorts are configured to be worn over existing pants and extend from a position covering the pelvic region of a wearer to a position proximate the knee region of the wearer.

Abstract: An improved user interface is provided for displaying selectable software functionality controls that are relevant to a selected object and that remain visibly available for use while the selected object is being edited. Upon selection of a particular object for editing, functionality available for editing the object is presented in a ribbon-shaped user interface above the software application workspace to allow the user ready and efficient access to functionality needed for editing the selected object. The display of relevant functionality controls is persisted until the user dismisses the display, selects another top-level functionality control or selects another object for editing.

Abstract: The present invention relates to enhancing the dosing efficiency of pharmaceutical dry powder formulations administered by pulmonary inhalation. In particular, the present invention relates to the provision of dry powder inhalers and dry powder compositions which reproducibly achieve a much higher delivered dose of the pharmaceutically active agent than currently achieved.

Abstract: An improved user interface is provided for displaying selectable software functionality controls and for presenting logical groupings of particular functionality controls associated with a selected top-level functionality. Underneath a row of top-level functionality tabs, functionalities controls associated with a given top-level functionality tab are presented in logical groupings. Selection of a particular tab switches modes of the user interface to present controls for functionalities associated with the selected tab.

Abstract: An improved user interface is provided for displaying selectable software functionality controls and for presenting logical groupings of particular functionality controls associated with a selected top-level functionality. Underneath a row of top-level functionality tabs, functionalities controls associated with a given top-level functionality tab are presented in logical groupings. Selection of a particular tab switches modes of the user interface to present controls for functionalities associated with the selected tab.

Abstract: An apparatus (1) for the atomisation of a liquid including: a piezoelectric substrate (5) having at least one working surface (7), at least one electrode (9) supported on the piezoelectric substrate (5), a signal generating means (21) for applying an ultrasonic signal to said electrode (9) for generating a surface acoustic wave (SAW) in the working surface (7) of the piezoelectric substrate (5); a liquid delivery arrangement (11) including a wick (17) in contact with the working surface (7) for delivering liquid thereof, wherein liquid delivered to the working surface (7) is atomised by SAW irradiation.

Abstract: An oven rack system has a two piece oven rack (100) with a cooking rack (102) and a base rack (104). The base rack (104) is adapted to remain stationary and may be positioned on ledges or other protrusions associated with inner liners of oven cavities. In one embodiment, a pair of angled pieces (118) extend between outer lateral braces (114) and a rear brace (106). The cooking rack (102) is adapted to slide on and be extendable relative to the base rack (104). A user can exert manual forces on the cooking rack (102) so as to move the cooking rack (102) relative to the base rack (104). The movement occurs in the absence of the requirement of any type of rotatable or rolling elements.

Abstract: The present invention relates to particles and to methods of making particles. In particular, the invention relates to methods of making composite active particles comprising a pharmaceutically active material for pulmonary inhalation, the method comprising a jet milling process.

Abstract: The present invention relates to particles and to methods of making particles. In particular, the invention relates to methods of making composite active particles comprising a pharmaceutically active material for pulmonary inhalation, the method comprising a jet milling process.

Abstract: The present invention is concerned with a refinement of the processing of particles that are to form a dry powder formulation which is to be administered to the lung using a dry powder inhaler (DPI) device. In particular, the present invention provides the processing of particles of active material and particles of carrier material in the presence of additive material to provide a powder composition which exhibits excellent powder properties and which is economical to produce.

Abstract: The present invention relates to pharmaceutical compositions which are useful in the treatment of diseases where excess mucus is present in the respiratory tract, such as cystic fibrosis and chronic obstructive pulmonary disease. In particular, the invention relates to pharmaceutical compositions for administration by pulmonary inhalation.

Abstract: Powder formulations for inhalation which comprise microparticles containing an antibiotic and magnesium stearate are useful for the treatment of bacterial infections associated with certain pulmonary diseases.

Abstract: The present invention relates to mucoactive agents, such as heparin which are useful in the treatment of diseases where excess mucus is present in the respiratory tract, such as cystic fibrosis and chronic obstructive pulmonary disease. In particular, the invention relates to pharmaceutical compositions for administration by pulmonary inhalation. It also relates to methods for producing particles suitable for pulmonary inhalation, such as spray drying or jet milling.

Abstract: The invention relates to an assembly comprising—an inserter (10) for insertion of a penetrating member (7) into a patient,—a penetrating member attached to the inserter (10) before use,—a base part comprises a position shaped to receive the penetrating member where the penetrating member can be attached to the base part during use and fastening means (2) which can provide for the base part to be attached to the patient, where the inserter (10) comprises inserter attachment means (14) locking the inserter (10) to the base part before and during insertion of the penetrating member (7) which inserter attachment means can be unlocked so that the inserted can be removed from the base part after insertion of the penetrating member (7), the inserter attachment means comprise at least one protruding part and at least one corresponding opening.

Abstract: The invention relates to an insertion device comprising—a penetrating member (50) connected to transformation means (52),—a moving part (38) comprising guiding means (39) which guiding means (39) restrict the movement of the transformation means (52) and guide the penetrating member (50) from a first to a second position in a first direction, i.e. the direction of insertion, towards the injection site, and—a stationary housing (30) comprising guiding means (32) which guiding means (32) restrict the movement of the moving part (38). The guiding means (32) guide the moving part (38) in a second direction which is linear and different from the first direction i.e. the direction of insertion.

Abstract: The present invention provides a novel class of macrocyclic compounds, which are useful as cysteine protease inhibitors. Also provided are novel intermediates and methods of preparing the compounds. The invention also provides pharmaceutical compositions comprising the compounds. The compounds and compositions are useful in methods of treating or preventing one or more diseases associated with cysteine protease activity, particularly those associated with calpain activity.

Abstract: The invention relates to a novel powder, it's method of manufacture and the use thereof in powder material processing, particularly in the manufacture of components formed from compacted powder e.g. discs, monoliths, layers or tablets. The powders comprise coated host particles wherein over 70% of the mass of the powder comprises coated particles smaller than 100 microns. The powders have particular application in the pharmaceutical industry and the technology described can be used to control the properties of active pharmaceutical ingredients. The powders (10) may comprise drug particles (12), carrier particles (14) and additives (16).

Abstract: The present invention relates to inhaler devices and bespoke pharmaceutical dry powder composition to be dispensed using such inhaler devices for pulmonary administration. In particular, the present invention relates to the provision of passive inhaler devices and dry powder compositions which are specifically formulated and prepared to be efficiently dispensed by such devices to reproducibly achieve a high delivered dose of the pharmaceutically active agent.

Abstract: An improved user interface is provided for displaying selectable software functionality controls that are relevant to a selected object and that remain visibly available for use while the selected object is being edited. Upon selection of a particular object for editing, functionality available for editing the object is presented in a ribbon-shaped user interface above the software application workspace to allow the user ready and efficient access to functionality needed for editing the selected object. The display of relevant functionality controls is persisted until the user dismisses the display, selects another top-level functionality control or selects another object for editing.