Abstract: Administration of carotenoids provide a prophylactic and/or therapeutic effect to subjects who are suffering from or at risk to develop cognitive decline or other neurological effects, such as diabetic complications, especially those related to neural tissues like retinopathy, peripheral neuropathy and central nervous system.

Abstract: In one embodiment, a system comprises a plurality of computing containers having processing resources for executing software workloads, a plurality of management processes for controlling access to the processing resources according to workload policy definitions, a data container for storing a plurality of workload policy definitions and associations between the plurality of workload policy definitions and the plurality of computing containers, and a configuration process for communicating workload policy definitions from the data container to the plurality of management processes.

Abstract: The invention provides methods and apparatus for the surface treatment of wood using synthetic pyrethroids such as bifenthrin as well as wood products made using those surface treatments.

Abstract: In one embodiment, a cluster system comprises a plurality of cluster nodes for executing a plurality of applications, and a management process for controlling the plurality of cluster nodes, wherein the management process is operable to identify a first application that is not meeting a service level objective (SLO), to select a cluster node that is not currently executing the first application, to progressively decrease routing of transactions to the selected cluster node for a second application, and to progressively increase routing of transactions to the selected cluster node for the first application.

Abstract: In an embodiment, a computing system comprises a plurality of resources, a first manager process for allocating the plurality of resources on a dynamic basis according to service level parameters, and a plurality of computing domains, wherein at least one application, a respective second manager process, and a respective performance monitor process are executed within each computing domain, and wherein the performance monitor generates performance data related to the execution of the at least one application and the second manager process requests additional resources from the first manager process in response to analysis of performance data in view of at least one service level parameter.

Abstract: The invention provides compounds of formula (1) wherein R1 is a hydrogen atom, an alkyl group having 1 to 6 carbon atoms or an alkoxy group having 1 to 6 carbon atoms; and R2 is a hydrogen atom, an alkyl group having 1 to 6 carbon atoms or an alkoxy group having 1 to 6 carbon atoms; and pharmaceutically acceptable salts thereof. The invention also relates to a process for obtaining the compounds, compositions containing them and their therapeutic use. The compounds display excellent activity against mammalian cancer cell lines.

Abstract: Systems and methods are disclosed for monitoring application performance. In one embodiment, the system comprises resource data including information on a plurality of resources, the resources including a plurality of computers, application data including one or more application profiles, each application profile having a performance profile and a resource profile, the resource profile including resource utilization information. The system further comprises policy data including one or more application performance policies and one or more resource utilization policies, and a monitoring agent to monitor the application data for compliance with the policy data.

Abstract: A process for treating wood comprising applying to the surface of the wood a boron based preservative which reacts with moisture within the wood to form a boron compound and alcohol and subjecting the wood with the applied preservative to a substantially moisture-free and enclosed environment for a period sufficient for the applied preservative to be absorbed into the wood and to produce the boron compound on reaction with the moisture in the wood and for the alcohol by-product of the reaction to be adsorbed within the wood structure.

Abstract: A novel class of antitumour compounds has been recognised based on the isolation from a new marine microbe, strain PO13-046, belonging to the genus Actinomadura sp.), of a compound designated IB-00208. The class of the formulae (I) or (II) where R1 can be hydrogen, acyl, alkyl, alkenyl, aryl, benzyl, alkali metal, and/or sugar, and R2 and R3 can be hydrogen, alkyl, or together R2 and R3 form an unsaturated bond. Such compounds demonstrate an interesting activity several cancel cell lines and against Gram-positive bacteria.

Abstract: A desk chair that is adjustable to accommodate a variety of different body sizes and shapes, and particularly to accommodate changes in body size and shape of children over several years between young childhood and adulthood. The chair includes a seat, a back support, and a pair of arm rests on opposite sides of the seat. The chair has adjustment mechanisms that allow the chair to be adjusted in several different ways, including the depth of the seat, the heights of the back support and the arm rests, and the positions of the arm rests in a substantially lateral plane relative to the seat and the back support. The chair also has a mechanism for adjusting the height of the seat over a range which is especially adapted for growing children, which results from positioning a height control adjustment mechanism substantially entirely within a support base for the chair, extending downwardly between the legs.

Abstract: A novel class of antitumour compounds has been recognised based on the isolation from a new marine microbe, strain PO13-046, belonging to the genus Actinomadura sp.), of a compound designated IB-00208. The class of the formulae (I) or (II) where R1 can be hydrogen, acyl, alkyl, alkenyl, aryl, benzyl, alkali metal, and/or sugar, and R2 and R3 can be hydrogen, alkyl, or together R2 and R3 form an unsaturated bond. Such compounds demonstrate an interesting activity several cancel cell lines and against Gram-positive bacteria.

Abstract: Citreamicins possess useful antitumor activity. Typically they are of formula, wherein R1 is selected from the group consisting of COCH2CH(CH3)2, COCH3 or H when R2 is CH3, or wherein R1 is COCH2CH(CH3)2, and R2 is H.

Abstract: The aim of the invention is to use at least one conditional promoter to implement a method for detecting one or more proteins interacting directly or indirectly with at least two other proteins during the formation of a protein complex, or during the inhibition of the formation of a protein complex.

Abstract: The aim of the invention is to use at least one conditional promoter to implement a method for detecting one or more proteins interacting directly or indirectly with at least two other proteins during the formation of a protein complex, or during the inhibition of the formation of a protein complex.