Abstract: A leakage detection method and system are used in blood treatment devices, such as a dialysis device used in continuous blood treatment/dialysis therapies, including renal replacement therapies.

Abstract: The present invention provides compounds of formula (I) and/or salts thereof and/or biologically active metabolites thereof and/or prodrugs thereof and/or solvates thereof and/or hydrates thereof and/or polymorphs thereof having affinity and selectivity for the gamma-aminobutyric acid A receptor subunit alpha 5 and act as GABAA ?5 positive allosteric modulators, thereby useful in the treatment or prevention of diseases related to the GABAA ?5 receptor, process for the preparation and intermediates of the preparation process thereof, pharmaceutical compositions comprising them alone or in combination with one or more other active ingredients and their use as medicaments.

Abstract: The present disclosure involves systems, software, and computer implemented methods for automatically recommending one or more frequencies for time series data. One example method includes receiving a request for an insight analysis for an input time series included in a dataset. For each of multiple frequencies to analyze, the input time series is transformed into a frequency time series. An absolute percentage change impact factor and an absolute trend impact factor are determined for each frequency time series. A frequency interest score is determined based on the determined absolute percentage change factors and the determined absolute trend impact factors, for each time frequency time series. The frequency interest score is provided for at least some of the frequency time series.

Abstract: The present disclosure involves systems, software, and computer implemented methods for automatically recommending one or more frequencies for time series data. One example method includes receiving a request for an insight analysis for an input time series included in a dataset. For each of multiple frequencies to analyze, the input time series is transformed into a frequency time series. An absolute percentage change impact factor and an absolute trend impact factor are determined for each frequency time series. A frequency interest score is determined based on the determined absolute percentage change factors and the determined absolute trend impact factors, for each time frequency time series. The frequency interest score is provided for at least some of the frequency time series.

Abstract: A distributed occupancy detection system includes plural networked node devices configured to be spatially distributed throughout a structure. Each node device includes an occupancy sensor that senses a presence characteristic indicative of an object being in a monitored area of the structure that is associated with the occupancy sensor. Each node device also includes one or more processors that determine a probability that the object is or was located in the structure based on the presence characteristic sensed by the occupancy sensor of a first node device and based on the presence characteristic sensed by the occupancy sensor of one or more neighboring node devices. The one or more processors determine whether the object is in the structure based on the probability.

Abstract: A transgenic animal model that is suitable for the cell or tissue specific assessing of thyroid hormone (TH) action in vivo is described. The recombinant DNA construct and methods suitable to generate such an animal are also provided. The assessment of TH action is based on a reporter that is dependent on an endogenously expressed thyroid hormone receptor (TR) and coregulators of said receptor.

Abstract: A lighting control system includes a monitoring assembly comprising a switch, an energy harvesting device, and radio circuitry. The switch is manually actuated to activate or deactivate network-controlled lamps. The energy harvesting device converts kinetic energy of the actuation of the switch into electric energy that powers the radio circuitry. The radio circuitry wirelessly broadcasts a radio control message to two or more networked controllers that control activation or deactivation of the lamps. The networked controllers communicate with each other and determine which of the networked controllers is a commander controller responsive to receiving the radio control message. The commander controller communicates a control message to other networked controllers to activate or deactivate the lamps based on the radio control message received from the monitoring assembly.

Abstract: A distributed occupancy detection system includes plural networked node devices configured to be spatially distributed throughout a structure. Each node device includes an occupancy sensor that senses a presence characteristic indicative of an object being in a monitored area of the structure that is associated with the occupancy sensor. Each node device also includes one or more processors that determine a probability that the object is or was located in the structure based on the presence characteristic sensed by the occupancy sensor of a first node device and based on the presence characteristic sensed by the occupancy sensor of one or more neighboring node devices. The one or more processors determine whether the object is in the structure based on the probability.

Abstract: A lighting control system includes a monitoring assembly comprising a switch, an energy harvesting device, and radio circuitry. The switch is manually actuated to activate or deactivate network-controlled lamps. The energy harvesting device converts kinetic energy of the actuation of the switch into electric energy that powers the radio circuitry. The radio circuitry wirelessly broadcasts a radio control message to two or more networked controllers that control activation or deactivation of the lamps. The networked controllers communicate with each other and determine which of the networked controllers is a commander controller responsive to receiving the radio control message. The commander controller communicates a control message to other networked controllers to activate or deactivate the lamps based on the radio control message received from the monitoring assembly.

Abstract: A transgenic animal model that is suitable for the cell or tissue specific assessing of thyroid hormone (TH) action in vivo is described. The recombinant DNA construct and methods suitable to generate such an animal are also provided. The assessment of TH action is based on a reporter that is dependent on an endogenously expressed thyroid hormone receptor (TR) and coregulators of said receptor.

Abstract: The present invention relates to a process for the synthesis of compounds of formula (I), wherein the meaning of R is dimethylamino or acetyl group, using the compound of formula (III) or (IV), wherein the meaning of R? is dimethylamino or 2-methyl-1,3-dioxan-2-yl group, as starting material and methoxymethyl lithium as reagent.

Abstract: The present invention relates to a process for the synthesis of compounds of formula (I), wherein the meaning of R is dimethylamino or acetyl group, using the compound of formula (III) or (IV), wherein the meaning of R? is dimethylamino or 2-methyl-1,3-dioxan-2-yl group, as starting material and methoxymethyl lithium as reagent.

Abstract: A method for operating a pump unit including a pump and a drive motor for the latter, the pump unit being disposed in a fluid circuit that is to be filled with a liquid to be moved and in which the liquid to be moved is moved using the pump unit. In order to provide a method in which the pump unit can be operated in a more energy-efficient manner, it is proposed that the fill status of the fluid circuit be determined and, with the use of a control unit, the working point of the pump unit be modified in operation thereof depending on the fill status of the fluid circuit. Also described is a pump unit for carrying out the method and to the use of a pump unit.

Abstract: A system for monitoring an area is provided. The system comprises a plurality of stationary sensors that can sense events and comprise a wireless output signal broadcast capability for transmitting output signals from the stationary sensors by a wireless communication protocol. The system further comprises gateway units connected to a wired backbone network and configured to transmit information relating to the output signals of the stationary sensors by a wired communication protocol, and a base station connected to the wired backbone network configured to receive the information transmitted by the gateway units on the wired communication protocol and to time-stamp the events signaled by the stationary sensors. The monitored area comprises sub-areas, and a group of stationary sensors are assigned to each of the sub-areas and to a gateway unit for directly receiving the output signals from the group of stationary sensors.

Abstract: A bulb lighting device is provided. The bulb device comprises a base, a driving electronics unit comprising a power supply electrically connected to the base and a battery connected to the power supply through a battery management unit, and a communication unit comprising a communication interface and at least one of a wireless unit and a power line unit, wherein the communication unit is electrically connected to the driving electronics unit. The bulb device further comprises an LED module having LED flight sources in an LED array together with an electric driving LED controller arranged inside an at least partially transparent envelope, wherein the LED module is electrically connected to the driving electronics unit, and a motion detector arranged inside the envelope and electrically connected to the driving electronics unit, wherein an output signal of the motion detector is forwarded outside of the bulb lighting device through the communication unit.

Abstract: In some embodiments, a fluorescent lighting device includes an arc tube; an amalgam flag including two opposing planar surfaces within the arc tube, the planar surfaces being adjacent to each other along a first edge of the planar surfaces and spaced apart from each other along a second edge of the planar surfaces; a quantity of amalgam deposited on the planar surfaces of the amalgam flag; and an electrode disposed within the arc tube to, at least in part, heat the quantity of amalgam when energized.

Abstract: According to some embodiments, a light cover includes a first end having an opening adapted to receive an illuminating bulb portion of a compact fluorescent lamp. The light cover may further include an outer surface contoured substantially in the shape of an illuminating bulb portion of an incandescent light bulb, wherein the outer surface is configured such that one or more open portions are provided.

Abstract: A compact fluorescent lamp (CFL) ballast driver includes first, second and neutral AC voltage terminals, a full wave rectifier between the first AC voltage terminal and the neutral AC input terminal, and a separate branch between the second AC voltage terminal and the neutral AC input terminal. A resonator circuit includes at least two inductors and provides its output voltage to a CFL lamp. The driver includes a first state detector circuit to monitor the first AC voltage terminal, and a second state detector circuit to monitor the second AC voltage terminal. The first and second state detector circuits activate respective first and second switches. The first switch shunts one inductor of the resonator circuit, and the second switch shunts another inductor of the resonator circuit. The driver can be housed in a CFL having a capper, a three-way lamp base adjacent to the capper and an arc tube.

Abstract: A compact fluorescent lamp (CFL) ballast driver includes first, second and neutral AC voltage terminals, a full wave rectifier between the first AC voltage terminal and the neutral AC input terminal, and a separate branch between the second AC voltage terminal and the neutral AC input terminal. A resonator circuit includes at least two inductors and provides its output voltage to a CFL lamp. The driver includes a first state detector circuit to monitor the first AC voltage terminal, and a second state detector circuit to monitor the second AC voltage terminal. The first and second state detector circuits activate respective first and second switches. The first switch shunts one inductor of the resonator circuit, and the second switch shunts another inductor of the resonator circuit. The driver can be housed in a CFL having a capper, a three-way lamp base adjacent to the capper and an arc tube.