Abstract: A lamp including a primary light source and a secondary light source, and a secondary light source control circuit configured to provide an operating voltage to the secondary light source. The secondary light source control circuit including a resistance element having an initial resistance which changes in response to being exposed to a temperature above a predetermined threshold. The secondary light source control circuit including a charging branch resistance-capacitance time constant that is configured to change with a change in the resistance element resistance.

Abstract: A fluorescent lighting device includes an arc tube, an exhaust tube extending from the arc tube, and an amalgam. A resistive heater is located adjacent to at least one of the arc tube and the exhaust tube. A power supply circuit is operatively coupled with the resistive heater. When the fluorescent lighting device is switched from an OFF state to an ON state, the power supply circuit temporarily energizes the resistive heater, thereby heating the at least one of the arc tube and the exhaust tube while the resistive heater is energized, and automatically de-energizing the resistive heater after said heating.

Abstract: Provided is a light assembly including a bulb, a lamp base enclosure having circuitry therein configured to supply power to the bulb, and an integrated and dial electrically coupled to the bulb and the lamp base. The dial is operable for selecting one of a plurality of predetermined power settings for the light assembly prior to installation.

Abstract: An optical microscope system for reconstructing an image of an object includes a means for creating a light beam profile, an optics for directing the light beam profile to the object, a moving means for implementing a scanning of the object with the light beam profile, a rotating means for enabling rotating the light beam profile and the object, and for changing the direction of scanning, and a detector for measuring the intensity of light passing through or reflected by the object. The image may be tomographically reconstructed using this intensity data associated with various directions as a plurality of projections.

Abstract: A discharge lamp having an improved run-up time is disclosed. In an embodiment, the discharge lamp includes a light-transmissive discharge tube extending from a first end to a second end and having an inner surface and an outer surface, a phosphor coating layered onto the inner surface of the discharge tube, and a fill gas composition capable of sustaining a discharge sealed within the discharge tube. Also included is a resistive heating wire positioned about the outer surface of the discharge tube. In some embodiments, a lamp driver circuit is included that operates when the lamp is turned ON to provide power to electrodes in the discharge tube and to provide power to the resistive heating wire, and operates to disconnect power from the resistive heating wire when the discharge lamp achieves a predetermined percentage of its stabilized lumen output.

Abstract: A system for monitoring an area is provided. The system comprises a plurality of stationary sensors that can sense events and comprise a wireless output signal broadcast capability for transmitting output signals from the stationary sensors by a wireless communication protocol. The system further comprises gateway units connected to a wired backbone network and configured to transmit information relating to the output signals of the stationary sensors by a wired communication protocol, and a base station connected to the wired backbone network configured to receive the information transmitted by the gateway units on the wired communication protocol and to time-stamp the events signaled by the stationary sensors. The monitored area comprises sub-areas, and a group of stationary sensors are assigned to each of the sub-areas and to a gateway unit for directly receiving the output signals from the group of stationary sensors.

Abstract: A fluorescent lighting device includes an arc tube, an exhaust tube extending from the arc tube, and an amalgam. A resistive heater is located adjacent to at least one of the arc tube and the exhaust tube. A power supply circuit is operatively coupled with the resistive heater. When the fluorescent lighting device is switched from an OFF state to an ON state, the power supply circuit temporarily energizes the resistive heater, thereby heating the at least one of the arc tube and the exhaust tube while the resistive heater is energized, and automatically de-energizing the resistive heater after said heating.

Abstract: The invention is an optical microscope system (1) for reconstructing an image of an object (14), comprising: a means (8) for creating a light beam profile (7), an optics for directing the light beam profile (7) to the object (14), a moving means for implementing a scanning of the object (14) with the light beam profile (7), a rotating means for enabling rotating vis-a-vis each other the light beam profile (7) and the object (14), and for changing the direction of scanning, and a detector (5) for measuring the intensity of light passing through or reflected by the object (14). Further, the invention is a method for reconstructing the image of an object (14) by means of an optical microscope system (1).

Abstract: The present invention relates to methods and kits useful for the detection of gene rearrangements and the diagnosis of a propensity to develop a disease condition caused by the gene rearrangements, wherein two PCR products are prepared from the 5? side and from the 3? side of a putative breakpoint of the gene of interest, and the ratio of the two products are measured.

Abstract: The present invention provides methods and kits useful for the detection of genetic alterations and to diagnose a disease condition caused by a genetic alteration. The invention involves two different PCR products, one control “unaltered” product and one sample product, which may contain “altered” DNA, that are mixed, denatured, and allowed to re-anneal. The DNA duplexes are then treated enzymatically or chemically to cleave single stranded or mismatched DNA regions resulting from the genetic alterations. The alterations are then quantitated by measuring a decrease in a fluorescent signal resulting from removal of the fluorescent tag. Further embodiments of the invention include a second, different fluorescent tag that is used to measure non-specific degradation of the duplexes. Other embodiments of the invention include the use of avidin coated microbeads to which the duplexes may be attached for quantitation by flow cytometry. Still further embodiments include biological microbeads for this purpose.

Abstract: The invention relates to biological microbeads, and in certain embodiments, to the use thereof in flow-cytometric applications. Biological microbeads are fixed cells that may be surface-modified with proteins or other molecules that have specific binding properties. These surface-bound proteins may bind to target compounds bearing fluorescent labels that facilitate detection by flow cytometry. Provided are compositions and methods for the use of biological microbeads as an inexpensive alternative to synthetic microbeads for in an extensive number of flow-cytometric applications, including quantitative PCR, detection of nucleases, detection of proteases, and immunoassays.

Abstract: A phototherapeutical apparatus and method are described. The apparatus includes an ultraviolet light source, an optical guidance system, and a patient interface. The patient interface is insertable at least partially into a body cavity and is operable to apply the guided ultraviolet light to a tissue surface of a body cavity. The method includes providing the phototherapeutical apparatus, preparing for the application of the phototherapeutical apparatus, inserting the patient interface at least partially into a body cavity, and applying the ultraviolet light by the patient interface to a tissue surface of a body cavity, wherein the tissue of the body cavity has an inflammatory or a hyperproliferative disease. The inflammatory diseases include rhinitis, sinusitis and rhinosinusitis. A photochemotherapeutical method is also described, using photosensitizing substances, such as psoralen before treatment with ultraviolet light.

Abstract: A phototherapeutical apparatus and method are described. The apparatus includes an ultraviolet light source, an optical guidance system, and a patient interface. The patient interface is insertable at least partially into a body cavity and is operable to apply the guided ultraviolet light to a tissue surface of a body cavity. The method includes providing the phototherapeutical apparatus, preparing for the application of the phototherapeutical apparatus, inserting the patient interface at least partially into a body cavity, and applying the ultraviolet light by the patient interface to a tissue surface of a body cavity, wherein the tissue of the body cavity has an inflammatory or a hyperproliferative disease. The inflammatory diseases include rhinitis, sinusitis and rhinosinusitis. A photochemotherapeutical method is also described, using photosensitizing substances, such as psoralen before treatment with ultraviolet light.

Abstract: A phototherapeutical apparatus and method are described. The apparatus includes an ultraviolet light source, an optical guidance system, and a patient interface. The patient interface is insertable at least partially into a body cavity and is operable to apply the guided ultraviolet light to a tissue surface of a body cavity. The method includes providing the phototherapeutical apparatus, preparing for the application of the phototherapeutical apparatus, inserting the patient interface at least partially into a body cavity, and applying the ultraviolet light by the patient interface to a tissue surface of a body cavity, wherein the tissue of the body cavity has an inflammatory or a hyperproliferative disease. The inflammatory diseases include rhinitis, sinusitis and rhinosinusitis. A photochemotherapeutical method is also described, using photosensitizing substances, such as psoralen before treatment with ultraviolet light.

Abstract: A phototherapeutical apparatus and method are described. The apparatus includes an ultraviolet light source, an optical guidance system, and a patient interface. The patient interface is insertable at least partially into a body cavity and is operable to apply the guided ultraviolet light to a tissue surface of a body cavity. The method includes providing the phototherapeutical apparatus, preparing for the application of the phototherapeutical apparatus, inserting the patient interface at least partially into a body cavity, and applying the ultraviolet light by the patient interface to a tissue surface of a body cavity, wherein the tissue of the body cavity has an inflammatory or a hyperproliferative disease. The inflammatory diseases include rhinitis, sinusitis and rhinosinusitis. A photochemotherapeutical method is also described, using photosensitizing substances, such as psoralen before treatment with ultraviolet light.

Abstract: A phototherapeutical apparatus is described, including a light source, generating high intensity visible light, in some embodiments in combination with ultraviolet light, an optical guidance system, and a patient interface. The patient interface can be insertable at least partially into a nasal cavity and is operable to apply the generated light to a tissue surface of the nasal cavity. Applying the apparatus includes providing the phototherapeutical apparatus, preparing for the application of the apparatus, inserting the patient interface into the nasal cavity, and applying the generated light by the patient interface to a tissue surface of the nasal cavity, wherein the tissue of the nasal cavity has an inflammatory or a hyperproliferative disease. The inflammatory diseases include rhinitis, sinusitis, and rhinosinusitis. A photodynamical therapy is also described, applying photosensitizing substances before the treatment with light.

Abstract: A phototherapeutical apparatus and method are described. The apparatus includes an ultraviolet light source, an optical guidance system, and a patient interface. The patient interface is insertable at least partially into a body cavity and is operable to apply the guided ultraviolet light to a tissue surface of a body cavity. The method includes providing the phototherapeutical apparatus, preparing for the application of the phototherapeutical apparatus, inserting the patient interface at least partially into a body cavity, and applying the ultraviolet light by the patient interface to a tissue surface of a body cavity, wherein the tissue of the body cavity has an inflammatory or a hyperproliferative disease. The inflammatory diseases include rhinitis, sinusitis and rhinosinusitis. A photochemotherapeutical method is also described, using photosensitizing substances, such as psoralen before treatment with ultraviolet light.

Abstract: The invention relates to the detection of the presence and/or conformation change of the cell surface receptors, pumps or proteins, when two different antibodies and optionally ligands are bound to the receptors, pumps and/or proteins recognized by the antibodies, and the change in the antibody-binding is measured. The method can be used for the determination of cytostatic drug combination, effective in case of multidrug resistance wherein the native cells are combined in vitro with the drug or drug combination to be tested, and the sample is tested with the method mentioned above. The method can be used for the detection of the efficiency of multidrug-resistance modulators wherein the method according is carried out in the presence of known modulator or a modulator to be tested, and the resulting activity values are compared.

Abstract: A phototherapeutical apparatus is described, including a light source, generating high intensity visible light, in some embodiments in combination with ultraviolet light, an optical guidance system, and a patient interface. The patient interface can be insertable at least partially into a nasal cavity and is operable to apply the generated light to a tissue surface of the nasal cavity. Applying the apparatus includes providing the phototherapeutical apparatus, preparing for the application of the apparatus, inserting the patient interface into the nasal cavity, and applying the generated light by the patient interface to a tissue surface of the nasal cavity, wherein the tissue of the nasal cavity has an inflammatory or a hyperproliferative disease. The inflammatory diseases include rhinitis, sinusitis, and rhinosinusitis. A photodynamical therapy is also described, applying photosensitizing substances before the treatment with light.

Abstract: The present invention near field scanning optical microscope NSOM, and related method thereof, provides a high resolution image of a sample in aqueous solution without damaging the sample. This attribute will greatly expand the applications and utility of a NSOM in biomedicine, among other fields. Moreover, the NSOM can be further extended to include signals other than light. In operation, a pipette is filled with an electrolyte solution (aqueous solution) and lowered through the reservoir toward the surface of the sample while the current between the electrode inside the pipette and the electrode in the reservoir is monitored. As the tip of the pipette approaches the surface, the ion current decreases because the space through which ions can flow is reduced. The pipette is then scanned laterally over the surface and the path of the tip pipette follows the topography of the surface.