Patents by Inventor Geoffrey von Maltzahn

Geoffrey von Maltzahn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of use of seed-origin endophyte populations
    Patent number: 9622485
    Abstract: This application relates to methods and materials for providing a benefit to a seed or seedling of an agricultural plant (e.g., an agricultural grass plant), or the agricultural plant derived from the seed or seedling. For example, this application provides purified bacterial populations that include novel seed-origin bacterial endophytes, and synthetic combinations of seeds and/or seedlings (e.g., cereal seeds and/or seedlings) with heterologous seed-derived bacterial endophytes.
    Type: Grant
    Filed: May 3, 2016
    Date of Patent: April 18, 2017
    Assignee: Indigo Ag, Inc.
    Inventors: Geoffrey von Maltzahn, Richard Bailey Flavell, Gerardo V. Toledo, Slavica Djonovic, Luis Miguel Marquez, David Morris Johnston, Yves Alain Millet, Jeffrey Lyford, Alexander Naydich, Craig Sadowski
  • Charged nutritive proteins and methods
    Patent number: 9611298
    Abstract: Charged nutritive proteins are provided. In some embodiments the nutritive proteins an aqueous solubility of at least 12.5 g/L at pH 7. In some embodiments the nutritive proteins an aqueous solubility of at least 50 g/L at pH 7. In some embodiments the nutritive proteins an aqueous solubility of at least 100 g/L at pH 7.
    Type: Grant
    Filed: July 22, 2014
    Date of Patent: April 4, 2017
    Assignee: Axcella Health Inc.
    Inventors: David Arthur Berry, Brett Adam Boghigian, Nathaniel W. Silver, Geoffrey von Maltzahn, Michael Hamill, Rajeev Chillakuru, John F. Kramarczyk
  • Nutritive proteins and methods
    Patent number: 9605040
    Abstract: Nutritive proteins are provided. In some embodiments the nutritive proteins comprise at least one of a level of a) a ratio of branch chain amino acid residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of branch chain amino acid residues to total amino acid residues present in whey protein; b) a ratio of leucine residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of leucine residues to total amino acid residues present in whey protein; and c) a ratio of essential amino acid residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of essential amino acid residues to total amino acid residues present in whey protein.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: March 28, 2017
    Assignee: Axcella Health Inc.
    Inventors: Geoffrey von Maltzahn, Michael J. Hamill, Rajeev Chillakuru, John F. Kramarczyk, David Arthur Berry, Brett Adam Boghigian, Nathaniel W. Silver
  • Nutritive fragments, proteins and methods
    Patent number: 9598474
    Abstract: Nutritive proteins are provided. In some embodiments the nutritive proteins comprise a first polypeptide sequence comprising a fragment of a naturally-occurring nutritive protein. In some embodiments the fragment comprises at least one of a) an enhanced ratio of branch chain amino acid residues to total amino acid residues present in the nutritive protein; b) an enhanced ratio of leucine residues to total amino acid residues present in the nutritive protein; and c) an enhanced ratio of essential amino acid residues to total amino acid residues present in the nutritive protein.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: March 21, 2017
    Assignee: Axcella Health, Inc.
    Inventors: David Arthur Berry, Brett Adam Boghigian, Nathaniel W. Silver, Geoffrey von Maltzahn, Rajeev Chillakuru, Michael Hamill, John F. Kramarczyk
  • Compositions and methods
    Patent number: 9585921
    Abstract: Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.
    Type: Grant
    Filed: October 15, 2015
    Date of Patent: March 7, 2017
    Assignee: SERES THERAPEUTICS, INC.
    Inventors: Gregory McKenzie, Mary-Jane Lombardo McKenzie, David N. Cook, Marin Vulic, Geoffrey von Maltzahn, Brian Goodman, John Grant Aunins, Matthew R. Henn, David Arthur Berry, Jonathan Winkler
  • AGRICULTURAL ENDOPHYTE-PLANT COMPOSITIONS, AND METHODS OF USE
    Publication number: 20170020138
    Abstract: This application relates to methods and materials for providing a benefit to a seed or seedling of an agricultural plant (e.g., an agricultural grass plant or a Gycine plant), or the agricultural plant derived from the seed or seedling. For example, this application provides purified bacterial populations that include novel seed bacterial endophytes, and synthetic combinations of seeds and/or seedlings (e.g., cereal or soy seeds and/or cereal or soy seedlings) with heterologous seed-derived bacterial endophytes.
    Type: Application
    Filed: September 4, 2014
    Publication date: January 26, 2017
    Inventors: Geoffrey VON MALTZAHN, Richard Bailey FLAVELL, Gerardo V. TOLEDO, Allison JACK, David Morris JOHNSTON, Slavica DJONOVIC, Luis Miguel MARQUEZ, Yves Alain MILLET, Craig SADOWSKI, Jeffrey LYFORD, Alexander NAYDICH
  • Synergistic bacterial compositions and methods of production and use thereof
    Patent number: 9533014
    Abstract: Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
    Type: Grant
    Filed: January 8, 2015
    Date of Patent: January 3, 2017
    Assignee: Seres Therapeutics, Inc.
    Inventors: Matthew R. Henn, Geoffrey von Maltzahn, Anthony Mario D'Onofrio, Kevin Daniel Litcofsky, David Arthur Berry, David N. Cook, Noubar B. Afeyan, John Grant Aunins
  • Methods of use of seed-origin endophyte populations
    Patent number: 9532572
    Abstract: This application relates to methods and materials for providing a benefit to a seed or seedling of an agricultural plant (e.g., an agricultural grass plant), or the agricultural plant derived from the seed or seedling. For example, this application provides purified bacterial populations that include novel seed-origin bacterial endophytes, and synthetic combinations of seeds and/or seedlings (e.g., cereal seeds and/or seedlings) with heterologous seed-derived bacterial endophytes.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: January 3, 2017
    Assignee: Indigo Ag, Inc.
    Inventors: Geoffrey von Maltzahn, Richard Bailey Flavell, Gerardo V. Toledo, Slavica Djonovic, Luis Miguel Marquez, David Morris Johnston, Yves Alain Millet, Jeffrey Lyford, Alexander Naydich, Craig Sadowski
  • Methods of use of seed-origin endophyte populations
    Patent number: 9532573
    Abstract: This application relates to methods and materials for providing a benefit to a seed or seedling of an agricultural plant (e.g., an agricultural grass plant), or the agricultural plant derived from the seed or seedling. For example, this application provides purified bacterial populations that include novel seed-origin bacterial endophytes, and synthetic combinations of seeds and/or seedlings (e.g., cereal seeds and/or seedlings) with heterologous seed-derived bacterial endophytes.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: January 3, 2017
    Assignee: Indigo Ag, Inc.
    Inventors: Geoffrey von Maltzahn, Craig Sadowski, Richard Bailey Flavell, Gerardo V. Toledo, Slavica Djonovic, Luis Miguel Marquez, David Morris Johnston, Yves Alain Millet, Jeffrey Lyford, Alexander Naydich
  • DESIGNED COMPLEX ENDOPHYTE COMPOSITIONS AND METHODS FOR IMPROVED PLANT TRAITS
    Publication number: 20160366892
    Abstract: This invention relates to methods and materials for providing a benefit to a plant by associating the plant with a complex endophyte comprising a host fungus further comprising a component bacterium, including benefits to a plant derived from a seed or other plant element treated with a complex endophyte. For example, this invention provides purified complex endophytes, purified complex endophyte components such as bacteria or fungi, synthetic combinations comprising said complex endophytes and/or components, and methods of making and using the same.
    Type: Application
    Filed: April 29, 2016
    Publication date: December 22, 2016
    Inventors: Karen V. Ambrose, Brett A. Boghigian, Slavica Djonovic, Paul Andrew Gray, Gerardo V. Toledo, Luis Miguel Marquez, Julianne Naomi Pelaez, Geoffrey von Maltzahn
  • Nutritive Polypeptides and Formulations Thereof, and Methods of Production and Use Thereof
    Publication number: 20160339078
    Abstract: Nutritive polypeptides are provided herein. Also provided are various other embodiments including nucleic acids encoding the polypeptides, recombinant microorganisms that make the polypeptides, vectors for expressing the polypeptides, methods of making the polypeptides using recombinant microorganisms, compositions and formulations that comprise the polypeptides, and methods of using the polypeptides, compositions and formulations.
    Type: Application
    Filed: March 25, 2016
    Publication date: November 24, 2016
    Inventors: Michael Hamill, Brett Boghigian, Caitlyn Harvey, David Berry, David Young, Geoffrey Von Maltzahn, John Kramarczyk, Jameson Rogers, Kathryn Heard, Michael Doherty, Nathaniel Silver, Phillip Samayoa, Subhayu Basu, Shaila Rahman, Vimal Vaidya, Ying-Ja Chen
  • PLANTS CONTAINING BENEFICIAL ENDOPHYTES
    Publication number: 20160338360
    Abstract: This application relates to methods and materials for providing a benefit to a seed, seedling or plant by producing seeds that are internally colonized with endophytes. Beneficial endophytes with particular characteristics are provided. These may be used in the methods described to provide a benefit to a seed, seedling or plant.
    Type: Application
    Filed: December 24, 2014
    Publication date: November 24, 2016
    Applicants: INDIGO AG, INC., AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH
    Inventors: Birgit MITTER, Muhammad NAVEED, Teresa BERNINGER, Stephane COMPANT, Angela SESSITSCH, Geoffrey VON MALTZAHN, Richard Bailey FLAVELL, Gerardo V. TOLEDO, Slavica DJONOVIC, Luis Miguel MARQUEZ, David Morris JOHNSTON, Yves Alain MILLET, Jeffrey LYFORD, Jonathan W. LEFF, Phillip SAMAYOA, Craig SADOWSKI
  • METHOD FOR PROPAGATING MICROORGANISMS WITHIN PLANT BIOREACTORS AND STABLY STORING MICROORGANISMS WITHIN AGRICULTURAL SEEDS
    Publication number: 20160330976
    Abstract: The present invention relates to methods of scalably producing microorganisms by propagating them within plant tissues and introducing them into agricultural seeds to improve their shelf-life during long-term storage, to produce substances of interest, and to create libraries of microbes.
    Type: Application
    Filed: December 24, 2014
    Publication date: November 17, 2016
    Applicants: INDIGO AG, INC., AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH
    Inventors: Birgit MITTER, Muhammad NAVEED, Teresa BERNINGER, Stephane COMPANT, Angela SESSITSCH, Geoffrey VON MALTZAHN, Richard Bailey FLAVELL, Gerardo V. TOLEDO, Slavica DJONOVIC, Luis Miguel MARQUEZ, David Morris JOHNSTON, Yves Alain MILLET, Jeffrey LYFORD, Jonathan W. LEFF, Phillip SAMAYOA, Craig SADOWSKI
  • Glycan therapeutics and related methods thereof
    Patent number: 9492473
    Abstract: Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said glycan therapeutics, e.g. for the modulation of human gastrointestinal microbiota and to treat dysbioses.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: November 15, 2016
    Assignee: KALEIDO BIOSCIENCES, INC.
    Inventors: Geoffrey A. von Maltzahn, Jared Silverman, Yvonne J. Yamanaka, John Miles Milwid, John M. Geremia
  • Isolated Complex Endophyte Compositions and Methods for Improved Plant Traits
    Publication number: 20160316760
    Abstract: This invention relates to methods and materials for providing a benefit to a plant by associating the plant with a complex endophyte comprising a host fungus further comprising a component bacterium, including benefits to a plant derived from a seed or other plant element treated with a complex endophyte. For example, this invention provides purified complex endophytes, purified complex endophyte components such as bacteria or fungi, synthetic combinations comprising said complex endophytes and/or components, and methods of making and using the same.
    Type: Application
    Filed: April 29, 2016
    Publication date: November 3, 2016
    Inventors: Karen V. Ambrose, Brett A. Boghigian, Slavica Djonovic, Paul Andrew Gray, Gerardo V. Toledo, Luis Miguel Marquez, Geoffrey von Maltzahn
  • Bacterial Compositions and Methods of Use Thereof for Treatment of Immune System Disorders
    Publication number: 20160317653
    Abstract: Provided are compositions containing combinations of bacteria useful for the maintenance or restoration of a healthy microbiota in the gastrointestinal tract, or other niche of a mammalian subject, and methods for use thereof, in particular for the treatment, inhibition, or prevention of immune disorders such as allergies and asthma.
    Type: Application
    Filed: December 16, 2014
    Publication date: November 3, 2016
    Applicant: Seres Therapeutics, Inc.
    Inventors: David N. Cook, David Arthur Berry, Geoffrey von Maltzahn, Matthew R. Henn, Han Zhang, Brian Goodman
  • Compositions and methods
    Patent number: 9446080
    Abstract: Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: September 20, 2016
    Assignee: Seres Therapeutics, Inc.
    Inventors: Gregory McKenzie, Mary-Jane Lombardo McKenzie, David N. Cook, Marin Vulic, Geoffrey von Maltzahn, Brian Goodman, John Grant Aunins, Matthew R. Henn, David Arthur Berry, Jonathan Winkler
  • Methods of Use of Seed-Origin Endophyte Populations
    Publication number: 20160235074
    Abstract: This application relates to methods and materials for providing a benefit to a seed or seedling of an agricultural plant (e.g., an agricultural grass plant), or the agricultural plant derived from the seed or seedling. For example, this application provides purified bacterial populations that include novel seed-origin bacterial endophytes, and synthetic combinations of seeds and/or seedlings (e.g., cereal seeds and/or seedlings) with heterologous seed-derived bacterial endophytes.
    Type: Application
    Filed: May 3, 2016
    Publication date: August 18, 2016
    Inventors: Geoffrey von Maltzahn, Richard Bailey Flavell, Gerardo V. Toledo, Slavica Djonovic, Luis Miguel Marquez, David Morris Johnston, Yves Alain Millet, Jeffrey Lyford, Alexander Naydich, Craig Sadowski
  • Endophytes, associated compositions, and methods of use thereof
    Patent number: 9408394
    Abstract: Materials and methods for improving plant traits and for providing plant benefits are provided. In some embodiments, the materials, and methods employing the same, can comprise endophytes.
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: August 9, 2016
    Assignee: Indigo Agriculture, Inc.
    Inventors: Geoffrey von Maltzahn, Richard Bailey Flavell, Gerardo V. Toledo, Jonathan W. Leff, Phillip Samayoa, Luis Miguel Marquez, David Morris Johnston, Slavica Djonovic, Yves Alain Millet, Craig Sadowski, Jeffrey Lyford, Karen V. Ambrose, Xuecheng Zhang
  • Compositions and Formulations for Maintaining and Increasing Muscle Mass, Strength, and Performance and Methods of Production and Use Thereof
    Publication number: 20160219910
    Abstract: Nutritive polypeptides are provided herein. Also provided are various other embodiments including nucleic acids encoding the polypeptides, recombinant microorganisms that make the polypeptides, vectors for expressing the polypeptides, methods of making the polypeptides using recombinant microorganisms, compositions and formulations that comprise the polypeptides, and methods of using the polypeptides, compositions and formulations.
    Type: Application
    Filed: September 25, 2014
    Publication date: August 4, 2016
    Inventors: Nathaniel W. Silver, Ying-Ja Chen, David Arthur Berry, Michael J. Hamill, Subhayu Basu, Luke Hamm, Alison Williams, David V. Erbe, Geoffrey von Maltzahn