Patents by Inventor Geoffrey von Maltzahn

Geoffrey von Maltzahn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Seed-origin endophyte populations, compositions, and methods of use
    Patent number: 10499654
    Abstract: This application relates to methods and materials for providing a benefit to a seed or seedling of an agricultural plant (e.g., an agricultural grass plant), or the agricultural plant derived from the seed or seedling. For example, this application provides purified bacterial populations that include novel seed-origin bacterial endophytes, and synthetic combinations of seeds and/or seedlings (e.g., cereal seeds and/or seedlings) with heterologous seed-derived bacterial endophytes.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: December 10, 2019
    Assignee: Indigo Ag, Inc.
    Inventors: Geoffrey von Maltzahn, Richard Bailey Flavell, Gerardo V. Toledo, Slavica Djonovic, Luis Miguel Marquez, David Morris Johnston, Yves Alain Millet, Jeffrey Lyford, Alexander Naydich, Craig Sadowski
  • Seed-origin endophyte populations, compositions, and methods of use
    Patent number: 10492497
    Abstract: This application relates to methods and materials for providing a benefit to a seed or seedling of an agricultural plant (e.g., an agricultural grass plant), or the agricultural plant derived from the seed or seedling. For example, this application provides purified bacterial populations that include novel seed-origin bacterial endophytes, and synthetic combinations of seeds and/or seedlings (e.g., cereal seeds and/or seedlings) with heterologous seed-derived bacterial endophytes.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: December 3, 2019
    Assignee: Indigo Ag, Inc.
    Inventors: Geoffrey von Maltzahn, Richard Bailey Flavell, Gerardo V. Toledo, Slavica Djonovic, Luis Miguel Marquez, David Morris Johnston, Yves Alain Millet, Jeffrey Lyford, Alexander Naydich, Craig Sadowski
  • Synergistic Bacterial Compositions and Methods of Production and Use Thereof
    Publication number: 20190350988
    Abstract: Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
    Type: Application
    Filed: December 17, 2018
    Publication date: November 21, 2019
    Applicant: Seres Therapeutics, Inc.
    Inventors: Matthew R. Henn, Geoffrey von Maltzahn, Anthony Mario D'Onofrio, Kevin Daniel Litcofsky, David Arthur Berry, David N. Cook, Noubar B. Afeyan, John Grant Aunins
  • Isolated Complex Endophyte Compositions and Methods for Improved Plant Traits
    Publication number: 20190335757
    Abstract: This invention relates to methods and materials for providing a benefit to a plant by associating the plant with a complex endophyte comprising a host fungus further comprising a component bacterium, including benefits to a plant derived from a seed or other plant element treated with a complex endophyte. For example, this invention provides purified complex endophytes, purified complex endophyte components such as bacteria or fungi, synthetic combinations comprising said complex endophytes and/or components, and methods of making and using the same.
    Type: Application
    Filed: December 14, 2018
    Publication date: November 7, 2019
    Inventors: Karen V. Ambrose, Brett A. Boghigian, Slavica Djonovic, Paul Andrew Gray, Gerardo V. Toldedo, Luis Miguel Marquez, Geoffrey von Maltzahn
  • DESIGNED COMPLEX ENDOPHYTE COMPOSITIONS AND METHODS FOR IMPROVED PLANT TRAITS
    Publication number: 20190335759
    Abstract: This invention relates to methods and materials for providing a benefit to a plant by associating the plant with a complex endophyte comprising a host fungus further comprising a component bacterium, including benefits to a plant derived from a seed or other plant element treated with a complex endophyte. For example, this invention provides purified complex endophytes, purified complex endophyte components such as bacteria or fungi, synthetic combinations comprising said complex endophytes and/or components, and methods of making and using the same.
    Type: Application
    Filed: December 14, 2018
    Publication date: November 7, 2019
    Inventors: Karen V. Ambrose, Brett A. Boghigian, Slavica Djonovic, Paul Andrew Gray, Gerardo V. Toledo, Luis Miguel Marquez, Julianne Naomi Pelaez, Geoffrey von Maltzahn
  • Nutritive polypeptides and formulations thereof, and methods of production and use thereof
    Patent number: 10463711
    Abstract: Nutritive polypeptides are provided herein. Also provided are various other embodiments including nucleic acids encoding the polypeptides, recombinant microorganisms that make the polypeptides, vectors for expressing the polypeptides, methods of making the polypeptides using recombinant microorganisms, compositions and formulations that comprise the polypeptides, and methods of using the polypeptides, compositions and formulations.
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: November 5, 2019
    Assignee: Axcella Health Inc.
    Inventors: Michael Hamill, Brett Boghigian, Caitlyn Harvey, David Berry, David Young, Geoffrey Von Maltzahn, John Kramarczyk, Jameson Rogers, Kathryn Heard, Michael Doherty, Nathaniel Silver, Phillip Samayoa, Subhayu Basu, Shaila Rahman, Vimal Vaidya, Ying-Ja Chen
  • Charged nutritive proteins and methods
    Patent number: 10450350
    Abstract: Charged nutritive proteins are provided. In some embodiments the nutritive proteins an aqueous solubility of at least 12.5 g/L at pH 7. In some embodiments the nutritive proteins an aqueous solubility of at least 50 g/L at pH 7. In some embodiments the nutritive proteins an aqueous solubility of at least 100 g/L at pH 7.
    Type: Grant
    Filed: February 10, 2017
    Date of Patent: October 22, 2019
    Assignee: Axcella Health Inc.
    Inventors: David Arthur Berry, Brett Adam Boghigian, Nathaniel W. Silver, Geoffrey von Maltzahn, Michael Hamill, Rajeev Chillakuru, John F. Kramarczyk
  • PLANTS CONTAINING BENEFICIAL ENDOPHYTES
    Publication number: 20190297897
    Abstract: This application relates to methods and materials for providing a benefit to a seed, seedling or plant by producing seeds that are internally colonized with endophytes. Beneficial endophytes with particular characteristics are provided. These may be used in the methods described to provide a benefit to a seed, seedling or plant.
    Type: Application
    Filed: April 8, 2019
    Publication date: October 3, 2019
    Inventors: Birgit Mitter, Muhammad Naveed, Teresa Berninger, Stephane Compant, Angela Sessitsch, Geoffrey Von Maltzahn, Richard Bailey Flavell, Gerardo V. Toledo, Slavica Djonovic, Luis Miguel Marquez, David Morris Johnston, Yves Alain Millet, Jeffrey Lyford, Jonathan W. Leff, Phillip Samayoa, Craig Sadowski
  • GLYCAN POLYMERS AND RELATED METHODS THEREOF
    Publication number: 20190290675
    Abstract: Compositions of glycan polymers and methods of making and manufacturing the same are described herein. Also provided are methods of treating a disease or disorder with a glycan polymer preparation.
    Type: Application
    Filed: December 6, 2017
    Publication date: September 26, 2019
    Inventors: Molly Krisann Gibson, Christopher Matthew Liu, Geoffrey A. von Maltzahn, Han Yuan
  • Method for propagating microorganisms within plant bioreactors and stably storing microorganisms within agricultural seeds
    Patent number: 10362787
    Abstract: The present invention relates to methods of scalably producing microorganisms by propagating them within plant tissues and introducing them into agricultural seeds to improve their shelf-life during long-term storage, to produce substances of interest, and to create libraries of microbes.
    Type: Grant
    Filed: December 24, 2014
    Date of Patent: July 30, 2019
    Assignees: AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH, INDIGO AG, INC.
    Inventors: Birgit Mitter, Muhammad Naveed, Teresa Berninger, Stephane Compant, Angela Sessitsch, Geoffrey Von Maltzahn, Richard Bailey Flavell, Gerardo V. Toledo, Slavica Djonovic, Luis Miguel Marquez, David Morris Johnston, Yves Alain Millet, Jeffrey Lyford, Jonathan W. Leff, Phillip Samayoa, Craig Sadowski
  • Methods of Populating a Gastrointestinal Tract
    Publication number: 20190192581
    Abstract: Methods and compositions for populating the gastrointestinal tract of a subject are described. Methods include administering to a subject a therapeutic composition comprising a purified population of spore-forming bacteria produced by providing a fecal material and subjecting the material to a treatment step resulting in purification of spore-form ing bacteria. Methods include administering an amount effective to engraft and/or augment in the gastrointestinal tract in order to treat or prevent a dysbiosis in the mammalian subject.
    Type: Application
    Filed: August 1, 2018
    Publication date: June 27, 2019
    Inventors: Geoffrey von Maltzahn, Matthew R. Henn, David N. Cook, David Arthur Berry, Noubar B. Afeyan, Brian Goodman, Mary-Jane Lombardo McKenzie, Marin Vulic
  • Endophytes, Associated Compositions, and Methods of Use
    Publication number: 20190183085
    Abstract: Materials and methods for improving plant traits and for providing plant benefits are provided. In some embodiments, the materials, and methods employing the same, can comprise endophytes.
    Type: Application
    Filed: December 20, 2018
    Publication date: June 20, 2019
    Inventors: Geoffrey von Maltzahn, Richard Bailey Flavell, Gerardo V. Toledo, Jonathan W. Leff, Phillip Samayoa, Luis Miguel Marquez, David Morris Johnston, Slavica Djonovic, Yves Alain Millet, Craig Sadowski, Jeffrey Lyford, Karen V. Ambrose, Xuecheng Zhang
  • Glycan therapeutics and related methods thereof
    Patent number: 10314853
    Abstract: Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said gycan therapeutics, e.g. for the modulation of human gastrointestinal microbiota and to treat dysbioses.
    Type: Grant
    Filed: June 15, 2017
    Date of Patent: June 11, 2019
    Assignee: KALEIDO BIOSCIENCES, INC.
    Inventors: Geoffrey A. von Maltzahn, Jared Silverman, Yvonne J. Yamanaka, John Miles Milwid, John M. Geremia
  • Plants containing beneficial endophytes
    Patent number: 10271554
    Abstract: This application relates to methods and materials for providing a benefit to a seed, seedling or plant by producing seeds that are internally colonized with endophytes. Beneficial endophytes with particular characteristics are provided. These may be used in the methods described to provide a benefit to a seed, seedling or plant.
    Type: Grant
    Filed: December 24, 2014
    Date of Patent: April 30, 2019
    Assignee: AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH
    Inventors: Birgit Mitter, Muhammad Naveed, Teresa Berninger, Stephane Compant, Angela Sessitsch, Geoffrey Von Maltzahn, Richard Bailey Flavell, Gerardo V. Toledo, Slavica Djonovic, Luis Miguel Marquez, David Morris Johnston, Yves Alain Millet, Jeffrey Lyford, Jonathan W. Leff, Phillip Samayoa, Craig Sadowski
  • Synergistic bacterial compositions and methods of production and use thereof
    Patent number: 10258655
    Abstract: Provided are therapeutic compositions containing microbial populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: April 16, 2019
    Assignee: Seres Therapeutics, Inc.
    Inventors: Matthew R. Henn, Kevin Daniel Litcofsky, Anthony Mario D'Onofrio, Toshiro K. Ohsumi, Mary-Jane Lombardo McKenzie, Geoffrey von Maltzahn, David N. Cook, David Arthur Berry, Noubar B. Afeyan, John Grant Aunins
  • COMPOSITIONS AND METHODS
    Publication number: 20190099455
    Abstract: Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.
    Type: Application
    Filed: August 3, 2018
    Publication date: April 4, 2019
    Inventors: Gregory McKenzie, Mary-Jane Lombardo McKenzie, David N. Cook, Marin Vulic, Geoffrey von Maltzahn, Brian Goodman, John Grant Aunins, Matthew R. Henn, David Arthur Berry, Jonathan Winkler
  • GLYCAN THERAPEUTIC COMPOSITIONS AND RELATED METHODS THEREOF
    Publication number: 20190091249
    Abstract: Preparations of glycan therapeutics, pharmaceutical compositions, dietary supplements and medical foods thereof are provided, and methods of using said gycan therapeutics, e.g. in cancer therapy.
    Type: Application
    Filed: September 24, 2018
    Publication date: March 28, 2019
    Inventors: Geoffrey A. von Maltzahn, Yvonne J. Yamanaka, Jared Silverman, John Miles Milwid, Jacob Rosenblum Rubens, John M. Geremia
  • STREPTOMYCES ENDOPHYTE COMPOSITIONS AND METHODS FOR IMPROVED AGRONOMIC TRAITS IN PLANTS
    Publication number: 20190059390
    Abstract: This invention relates to methods and compositions for providing a benefit to a plant by associating the plant with a beneficial endophyte of the genus Streptomyces, including benefits to a plant derived from a seed or other plant element treated with said endophyte. For example, this invention provides purified endophytes, synthetic combinations comprising endophytes, and methods of making and using the same. In particular, this invention relates to compositions and methods of improving soybean and maize plants.
    Type: Application
    Filed: June 8, 2016
    Publication date: February 28, 2019
    Inventors: Slavica DJONOVIC, Elizabeth Alexa MCKENZIE, Gerardo V. TOLEDO, Craig SADOWSKI, Geoffrey VON MALTZAHN, Karen V. AMBROSE, Xuecheng ZHANG, David Morris JOHNSTON, Trudi A. GULICK
  • Isolated complex endophyte compositions and methods for improved plant traits
    Patent number: 10212940
    Abstract: This invention relates to methods and materials for providing a benefit to a plant by associating the plant with a complex endophyte comprising a host fungus further comprising a component bacterium, including benefits to a plant derived from a seed or other plant element treated with a complex endophyte. For example, this invention provides purified complex endophytes, purified complex endophyte components such as bacteria or fungi, synthetic combinations comprising said complex endophytes and/or components, and methods of making and using the same.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: February 26, 2019
    Assignee: Indigo Agriculture, Inc.
    Inventors: Karen V. Ambrose, Brett A. Boghigian, Slavica Djonovic, Paul Andrew Gray, Gerardo V. Toledo, Luis Miguel Marquez, Geoffrey von Maltzahn
  • Designed complex endophyte compositions and methods for improved plant traits
    Patent number: 10212944
    Abstract: This invention relates to methods and materials for providing a benefit to a plant by associating the plant with a complex endophyte comprising a host fungus further comprising a component bacterium, including benefits to a plant derived from a seed or other plant element treated with a complex endophyte. For example, this invention provides purified complex endophytes, purified complex endophyte components such as bacteria or fungi, synthetic combinations comprising said complex endophytes and/or components, and methods of making and using the same.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: February 26, 2019
    Assignee: Indigo Agriculture, Inc.
    Inventors: Karen V. Ambrose, Brett A. Boghigian, Slavica Djonovic, Paul Andrew Gray, Gerardo V. Toledo, Luis Miguel Marquez, Julianne Naomi Pelaez, Geoffrey von Maltzahn