Patents by Inventor Geoffrey von Maltzahn

Geoffrey von Maltzahn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synergistic bacterial compositions and methods of production and use thereof
    Patent number: 10864235
    Abstract: Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
    Type: Grant
    Filed: December 17, 2018
    Date of Patent: December 15, 2020
    Assignee: Seres Therapeutics, Inc.
    Inventors: Matthew R. Henn, Geoffrey von Maltzahn, Anthony Mario D'Onofrio, Kevin Daniel Litcofsky, David Arthur Berry, David N. Cook, Noubar B. Afeyan, John Grant Aunins
  • Synergistic Bacterial Compositions and Methods of Production and Use Thereof
    Publication number: 20200345792
    Abstract: Provided are therapeutic compositions containing microbial populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
    Type: Application
    Filed: December 21, 2018
    Publication date: November 5, 2020
    Applicant: SERES THERAPEUTICS, INC.
    Inventors: Matthew R. Henn, Kevin Daniel Litcofsky, Anthony Mario D'Onofrio, Toshiro K. Ohsumi, Mary-Jane Lombardo McKenzie, Geoffrey von Maltzahn, David N. Cook, David Arthur Berry, Noubar B. Afeyan, John Grant Aunins
  • Nutritive Polypeptides and Formulations Thereof, and Methods of Production and Use Thereof
    Publication number: 20200306342
    Abstract: Nutritive polypeptides are provided herein. Also provided are various other embodiments including nucleic acids encoding the polypeptides, recombinant microorganisms that make the polypeptides, vectors for expressing the polypeptides, methods of making the polypeptides using recombinant microorganisms, compositions and formulations that comprise the polypeptides, and methods of using the polypeptides, compositions and formulations.
    Type: Application
    Filed: March 16, 2020
    Publication date: October 1, 2020
    Inventors: Michael Hamill, Brett Boghigian, Caitlyn Harvey, David Berry, David Young, Geoffrey Von Maltzahn, John Kramarczyk, Jameson Rogers, Kathryn Heard, Michael Doherty, Nathaniel Silver, Phillip Samayoa, Subhayu Basu, Shaila Rahman, Vimal Vaidya, Ying-Ja Chen
  • METHODS AND COMPOSITIONS RELATING TO CHONDRISOMES FROM BLOOD PRODUCTS
    Publication number: 20200306316
    Abstract: Therapeutic chondrisome and mitoplast compositions and related methods are described.
    Type: Application
    Filed: November 30, 2016
    Publication date: October 1, 2020
    Inventors: Geoffrey von Maltzahn, John Miles Milwid, Michael Mee, Jacob Rosenblum Rubens, David Chess, Kyle Trudeau, Kiana Mahdaviani, Jacob Feala
  • METHODS AND COMPOSITIONS RELATING TO CHONDRISOMES FROM CULTURED CELLS
    Publication number: 20200306315
    Abstract: Therapeutic chondrisome compositions and related methods are described.
    Type: Application
    Filed: November 30, 2016
    Publication date: October 1, 2020
    Inventors: Geoffrey von Maltzahn, John Miles Milwid, Michael Mee, Jacob Rosenblum Rubens, David Chess, Kyle Trudeau, Kiana Mahdaviani, Jacob Feala
  • METHODS OF USE OF SEED-ORIGIN ENDOPHYTE POPULATIONS
    Publication number: 20200281210
    Abstract: This application relates to methods and materials for providing a benefit to a seed or seedling of an agricultural plant (e.g., an agricultural grass plant), or the agricultural plant derived from the seed or seedling. For example, this application provides purified bacterial populations that include novel seed-origin bacterial endophytes, and synthetic combinations of seeds and/or seedlings (e.g., cereal seeds and/or seedlings) with heterologous seed-derived bacterial endophytes.
    Type: Application
    Filed: October 18, 2019
    Publication date: September 10, 2020
    Inventors: Geoffrey von Maltzahn, Richard Bailey Flavell, Gerardo V. Toledo, Slavica Djonovic, Luis Miguel Marquez, David Morris Johnston, Yves Alain Millet, Jeffrey Lyford, Alexander Naydich, Craig Sadowski
  • endophyte compositions and methods for improved agronomic traits in plants
    Patent number: 10750711
    Abstract: This invention relates to methods and compositions for providing a benefit to a plant by associating the plant with a beneficial endophyte of the genus Streptomyces, including benefits to a plant derived from a seed or other plant element treated with said endophyte. For example, this invention provides purified endophytes, synthetic combinations comprising endophytes, and methods of making and using the same. In particular, this invention relates to compositions and methods of improving soybean and maize plants.
    Type: Grant
    Filed: June 8, 2016
    Date of Patent: August 25, 2020
    Assignee: INDIGO AG, INC.
    Inventors: Slavica Djonovic, Elizabeth Alexa McKenzie, Gerardo V. Toledo, Craig Sadowski, Geoffrey Von Maltzahn, Karen V. Ambrose, Xuecheng Zhang, David Morris Johnston, Trudi A. Gulick
  • Glycan therapeutics and related methods thereof
    Patent number: 10702542
    Abstract: Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said glycan therapeutics, e.g. for the modulation of human gastrointestinal microbiota and to treat dysbioses.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: July 7, 2020
    Assignee: KALEIDO BIOSCIENCES, INC.
    Inventors: Geoffrey A. von Maltzahn, Jared Silverman, Yvonne J. Yamanaka, John Miles Milwid, John M. Geremia
  • Nutritive Polypeptides and Formulations Thereof, and Methods of Production and Use Thereof
    Publication number: 20200188481
    Abstract: Nutritive polypeptides are provided herein. Also provided are various other embodiments including nucleic acids encoding the polypeptides, recombinant microorganisms that make the polypeptides, vectors for expressing the polypeptides, methods of making the polypeptides using recombinant microorganisms, compositions and formulations that comprise the polypeptides, and methods of using the polypeptides, compositions and formulations.
    Type: Application
    Filed: September 27, 2019
    Publication date: June 18, 2020
    Inventors: Michael Hamill, Brett Boghigian, Caitlyn Harvey, David Berry, David Young, Geoffrey Von Maltzahn, John Kramarczyk, Jameson Rogers, Kathryn Heard, Michael Doherty, Nathaniel Silver, Phillip Samayoa, Subhayu Basu, Shaila Rahman, Vimal Vaidya, Ying-Ja Chen
  • Seed endophytes across cultivars and species, associated compositions, and methods of use thereof
    Patent number: 10667523
    Abstract: Materials and methods for improving plant traits and for providing plant fitness benefits are provided. In some embodiments, the materials, and methods employing the same, can comprise endophytes.
    Type: Grant
    Filed: December 30, 2015
    Date of Patent: June 2, 2020
    Assignee: Indigo Ag, Inc.
    Inventors: Karen V. Ambrose, Nathan A. Billings, Slavica Djonovic, Richard Bailey Flavell, Trudi A. Gulick, David Morris Johnston, Jonathan W. Leff, Stephanie M. Liva, Jeffrey Lyford, Geoffrey Von Maltzahn, Luis Miguel Marquez, Yves Alain Millet, Craig Sadowski, Phillip Samayoa, Gerardo V. Toledo, David R. Weisman, Xuecheng Zhang
  • METHODS AND COMPOSITIONS FOR MODULATING A GENOME
    Publication number: 20200109398
    Abstract: Methods and compositions for modulating a target genome are disclosed.
    Type: Application
    Filed: December 6, 2019
    Publication date: April 9, 2020
    Inventors: Jacob Rosenblum Rubens, Geoffrey A. von Maltzahn, Robert James Citorik, Barrett Ethan Steinberg, Donghui Li
  • Charged Nutritive Proteins and Methods
    Publication number: 20200109175
    Abstract: Charged nutritive proteins are provided. In some embodiments the nutritive proteins an aqueous solubility of at least 12.5 g/L at pH 7. In some embodiments the nutritive proteins an aqueous solubility of at least 50 g/L at pH 7. In some embodiments the nutritive proteins an aqueous solubility of at least 100 g/L at pH 7.
    Type: Application
    Filed: September 10, 2019
    Publication date: April 9, 2020
    Inventors: David Arthur Berry, Brett Adam Boghigian, Nathaniel W. Silver, Geoffrey von Maltzahn, Michael Hamill, Rajeev Chillakuru, John F. Kramarczyk
  • GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF
    Publication number: 20200093851
    Abstract: Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said glycan therapeutics, e.g. for the modulation of human gastrointestinal microbiota and to treat dysbioses.
    Type: Application
    Filed: April 26, 2019
    Publication date: March 26, 2020
    Inventors: Geoffrey A. von Maltzahn, Jared Silverman, Yvonne J. Yamanaka, John Miles Milwid, John M. Geremia
  • GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF
    Publication number: 20200093845
    Abstract: Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said gycan therapeutics, e.g. for the modulation of human gastrointestinal microbiota and to treat dysbioses.
    Type: Application
    Filed: April 26, 2019
    Publication date: March 26, 2020
    Inventors: Geoffrey A. von Maltzahn, Jared Silverman, Yvonne J. Yamanaka, John Miles Milwid, John M. Geremia
  • COMPOSITIONS FOR FACILITATING MEMBRANE FUSION AND USES THEREOF
    Publication number: 20200060980
    Abstract: In some aspects, fusosome compositions and methods are described herein that comprise membrane enclosed preparations, comprising a fusogen. In some embodiments, the fusosome can the target cell, thereby delivering complex biologic agents to the target cell cytoplasm.
    Type: Application
    Filed: May 8, 2018
    Publication date: February 27, 2020
    Inventors: Geoffrey A. von Maltzahn, John Miles Milwid, Michael Travis Mee, Jacob Rosenblum Rubens, Nathan Wilson Stebbins, Molly Krisann Gibson, Neal Francis Gordon, Bo Zhang, Kyle Marvin Trudeau, Brigham Jay Hartley, Tamar Rose Putiri, Kiana Mahdaviani, Matthew Milnes Dobbin
  • MICROBIOME REGULATORS AND RELATED USES THEREOF
    Publication number: 20200009168
    Abstract: Compositions comprising microbiome regulators are provided, as well as methods of using the same for the modulation of the human microbiota and to treat or prevent related diseases, disorders, or conditions.
    Type: Application
    Filed: February 7, 2019
    Publication date: January 9, 2020
    Inventors: Geoffrey A. von Maltzahn, John M. Geremia
  • METHOD FOR PROPAGATING MICROORGANISMS WITHIN PLANT BIOREACTORS AND STABLY STORING MICROORGANISMS WITHIN AGRICULTURAL SEEDS
    Publication number: 20200008431
    Abstract: The present invention relates to methods of scalably producing microorganisms by propagating them within plant tissues and introducing them into agricultural seeds to improve their shelf-life during long-term storage, to produce substances of interest, and to create libraries of microbes.
    Type: Application
    Filed: July 15, 2019
    Publication date: January 9, 2020
    Inventors: Birgit MITTER, Muhammad NAVEED, Teresa BERNINGER, Stephane COMPANT, Angela SESSITSCH, Geoffrey VON MALTZAHN, Richard Bailey FLAVELL, Gerardo V. TOLEDO, Slavica DJONOVIC, Luis Miguel MARQUEZ, David Morris JOHNSTON, Yves Alain MILLET, Jeffrey LYFORD, Jonathan W. LEFF, Phillip SAMAYOA, Craig SADOWSKI
  • METHODS AND COMPOSITIONS OF CHONDRISOMES
    Publication number: 20190374582
    Abstract: Therapeutic chondrisome compositions and related methods are described.
    Type: Application
    Filed: January 18, 2019
    Publication date: December 12, 2019
    Inventors: Geoffrey A. von Maltzahn, John Miles Milwid, Michael Travis Mee, Jacob Rosenblum Rubens, David Chess, Kyle Marvin Trudeau, Kiana Mahdaviani, Jacob Feala, James D. McCully, Douglas B. Cowan
  • Methods of use of seed-origin endophyte populations
    Patent number: 10499653
    Abstract: This application relates to methods and materials for providing a benefit to a seed or seedling of an agricultural plant (e.g., an agricultural grass plant), or the agricultural plant derived from the seed or seedling. For example, this application provides purified bacterial populations that include novel seed-origin bacterial endophytes, and synthetic combinations of seeds and/or seedlings (e.g., cereal seeds and/or seedlings) with heterologous seed-derived bacterial endophytes.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: December 10, 2019
    Assignee: Indigo Ag, Inc.
    Inventors: Geoffrey von Maltzahn, Richard Bailey Flavell, Gerardo V. Toledo, Slavica Djonovic, Luis Miguel Marquez, David Morris Johnston, Yves Alain Millet, Jeffrey Lyford, Alexander Naydich, Craig Sadowski
  • Methods of use of seed-origin endophyte populations
    Patent number: 10499652
    Abstract: This application relates to methods and materials for providing a benefit to a seed or seedling of an agricultural plant (e.g., an agricultural grass plant), or the agricultural plant derived from the seed or seedling. For example, this application provides purified bacterial populations that include novel seed-origin bacterial endophytes, and synthetic combinations of seeds and/or seedlings (e.g., cereal seeds and/or seedlings) with heterologous seed-derived bacterial endophytes.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: December 10, 2019
    Assignee: Indigo Ag, Inc.
    Inventors: Geoffrey von Maltzahn, Richard Bailey Flavell, Gerardo V. Toledo, Slavica Djonovic, Luis Miguel Marquez, David Morris Johnston, Yves Alain Millet, Jeffrey Lyford, Alexander Naydich, Craig Sadowski