Abstract: A wind turbine rotor blade has a blade root, a blade tip and a blade depth varying over the length of the rotor blade. The rotor blade has a maximum blade depth at a longitudinal position between the blade root and the blade tip. The blade depth in an outer longitudinal section, which extends over a length of 20% or more of the blade length, lies in a range from 20% to 30% of the maximum blade depth.

Abstract: A cyclosporin derivative of general Formula (I) or a pharmaceutically compatible salt thereof, which have a pharmaceutical effectiveness, for example in the case of chronic inflammatory diseases. The cyclosporin derivatives are preferably free from a peptide section capable of passing through the membrane of a biological cell.

Abstract: The present invention relates to an active ingredient-peptide construct for extracellular concentration, a process for the concentration of active ingredients in an extracellular space of a multicellular object, the use of the active ingredient-peptide construct according to the invention for the production of a medicinal product and a pharmaceutical composition containing the active ingredient-peptide construct according to the invention.

Abstract: A laser processing unit includes a first working area for laser processing of a workpiece, a second working area for laser processing of a workpiece, and a dividing wall adapted to separate the first working area from the second working area between, the dividing wall having individual interconnected sections and being moveable in a vertical direction.

Abstract: A mechanical arrangement for processing pipes by cutting using a cutting beam has a cutting head, a pipe holder, a catching lance and a stripper. The stripper is transferable relative to a processing axis of the cutting head in the longitudinal direction of the pipe to various positions by means of a positioning movement.

Abstract: Wind turbine rotor blade with a blade tip, a blade root, a leading edge, a trailing edge, a pressure side, a suction side and a cross-section, which changes from the blade tip to the blade root, the longitudinal portion being arranged between the blade root and the middle of the rotor blade, has the following: a convex pressure side portion, which extends from the leading edge up to a pressure-side inflection point, a concave pressure side addition portion, which connects with the pressure-side inflection point with a continuous curvature and extends up to the trailing edge, a convex suction side portion, which extends from the leading edge up to a suction-side kink or inflection point, and a suction side addition portion, which extends from the suction side kink or inflection point up to the trailing edge.

Abstract: Wind turbine rotor blade with a longitudinal axis, a blade tip, a blade root, a leading edge, a trailing edge and a cross-section arranged orthogonally to the longitudinal axis and changing from the blade root to the blade tip, is the cross-section being formed at the blade root and in the middle of the rotor blade by an aerodynamic profile, and an imaginary reference plane arranged with respect to the rotor blade which includes the longitudinal axis of the rotor blade, wherein, in a cross-section, an angle ?3 is defined between the reference plane and a straight line, which connects the longitudinal axis with the trailing edge, and describes the position of the trailing edge, wherein the angle ?3 increases with decreasing distance from the blade root in a first longitudinal portion of the rotor blade and decreases with decreasing distance from the blade root in a second longitudinal portion.

Abstract: The present invention relates to the use of certain derivatives of cycloheximide or the pharmaceutically acceptable salts thereof for the manufacture of a medicament for the treatment or prevention of ischaemias, of cardiopathies, of endothelial disorders, of traumata, of necroses, of pulmonary disorders, of vascular disorders, of forms of shock, of blood flow impairments or of stroke; or for the manufacture of a medicament for the treatment or prevention of diseases caused by ischaemia; or for the manufacture of a composition for the preservation and/or storage of transplants, especially of organs.

Abstract: The present invention is based on the finding that the cis/trans isomerisation of secondary amide peptide bonds in oligo- and polypeptides can be catalytically promoted. This catalysis is effected by enzymes which are hereinafter called “secondary amide peptide bond cis/trans isomerases (APIases). It can be assumed that the APIase activity plays a central role in a number of pathophysiological processes. Thus, the invention relates to pharmaceutical compositions comprising substances which inhibit APIase activity.

Abstract: The present invention relates to the use of certain spiro, ketone and carboxylic acid compounds for the inhibition of the peptidyl-prolyl cis/trans isomerase activity of cyclophilins and the use of these compounds for the production of a cosmetic or pharmaceutical composition for the promotion of hair growth or for the treatment or prevention of inflammatory autoimmune diseases, of diseases caused by fungi, of bacterial infections, of viral infections, of diseases caused by parasites, protozoa or worms, of cancer, of diseases of cells, of fibrosing diseases, and of non-neoplastic changes and diseases which are attributable to prions and changes in the structure and function of cellular proteins and cells.

Abstract: The present invention relates to a device for the analysis of interactions between biomolecules comprising a support, on which a plurality of biomolecules are immobilized on the surface of a support material in a regular or irregular manner by a linker, whereby two biomolecules are bound to each linker. Further, the present invention relates to a method for the detection of interactions between biopolymers immobilized on a surface comprising the steps of providing a device of one of the preceding claims, adjusting a defined distance between two biopolymers immobilized on the surface and detection of a signal generated by the interaction between the two biopolymers.

Abstract: The present invention is based on the finding that the cis/trans isomerisation of secondary amide peptide bonds in oligo- and polypeptides can be catalytically promoted. This catalysis is effected by enzymes which are hereinafter called “secondary amide peptide bond cis/trans isomerases (APIases). It can be assumed that the APIase activity plays a central role in a number of pathophysiological processes. Thus, the invention relates to pharmaceutical compositions comprising substances which inhibit APIase activity.

Abstract: The invention concerns an ultra-wideband information transmission method comprising a first encoding step on the part of the transmitter, in which a pulse group which is formed from a predetermined number of individual pulses is encoded in dependence on values of a random number sequence, and a correlation step on the part of the receiver in which correlation of a reception signal with a signal pattern is effected, wherein the signal pattern corresponds to the whole pulse group to be expected when using the same values of the random number sequence.

Abstract: A multimeter has a housing with at least three input connections, configured as female connectors, for connecting to two measurement lines. When a measurement variable is changed, it is possible to connect at least one of the measurement lines to another input connection. The multimeter has a measurement-range switch which can be moved to a switching position associated with the selected measurement variables, and a mechanical blocking apparatus coupled to the switch. The blocking apparatus allows specific input connections to be blocked such that contact can be made only with the input connections which have an associated measurement variable which corresponds to the measurement variable set by the switch. The blocking apparatus is formed as a pivotable angle lever, and the switch moves end regions of strip-shaped angle limbs of the angle lever to a position aligned with the input connections to be blocked.

Abstract: A mechanical arrangement for processing pipes by cutting using a cutting beam has a cutting head, a pipe holder, a catching lance and a stripper. The stripper is transferable relative to a processing axis of the cutting head in the longitudinal direction of the pipe to various positions by means of a positioning movement.

Abstract: The present invention relates to a method for identifying and producing effectors of peptidyl-prolyl cis/trans isomerases which can be activated by calmodulin. The invention also relates to the use of the identified effectors for the production of medicaments and to screening methods and kits.

Abstract: A multimeter has a housing with at least three input connections, configured as female connectors, for connecting to two measurement lines. When a measurement variable is changed, it is possible to connect at least one of the measurement lines to another input connection. The multimeter has a measurement-range switch which can be moved to a switching position associated with the selected measurement variables, and a mechanical blocking apparatus coupled to the switch. The blocking apparatus allows specific input connections to be blocked such that contact can be made only with the input connections which have an associated measurement variable which corresponds to the measurement variable set by the switch. The blocking apparatus is formed as a pivotable angle lever, and the switch moves end regions of strip-shaped angle limbs of the angle lever to a position aligned with the input connections to be blocked.

Abstract: The present invention is based on the finding that the cis/trans isomerisation of secondary amide peptide bonds in oligo- and polypeptides can be catalytically promoted. This catalysis is effected by enzymes which are hereinafter called “secondary amide peptide bond cis/trans isomerases (APIases). It can be assumed that the APIase activity plays a central role in a number of pathophysiological processes. Thus, the invention relates to pharmaceutical compositions comprising substances which inhibit APIase activity.

Abstract: The invention provides new spiro and carboxylic acid derivatives, pharmaceutically compositions comprising them and their use for the preparation of pharmaceutical compositions.

Abstract: A laser processing unit includes a first working area for laser processing of a workpiece, a second working area for laser processing of a workpiece, and a dividing wall adapted to separate the first working area from the second working area between, the dividing wall having individual interconnected sections and being moveable in a vertical direction.