Patents by Inventor Habib Skaff

Habib Skaff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS
    Publication number: 20150232616
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Application
    Filed: February 5, 2015
    Publication date: August 20, 2015
    Inventors: Kevin N. Sill, Habib Skaff, Kurt Breitenkamp
  • Hybrid block copolymer micelles with mixed stereochemistry for encapsulation of hydrophobic agents
    Patent number: 8980326
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Grant
    Filed: September 1, 2010
    Date of Patent: March 17, 2015
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kevin N. Sill, Habib Skaff, Kurt Breitenkamp
  • AERATION TINES AND METHODS OF MAKING AERATION TINES
    Publication number: 20140224512
    Abstract: An aeration tine includes a non-boronized elongated body including a first longitudinal end configured to support the tine relative to an aeration machine, and a second longitudinal end opposite the first longitudinal end, and a tapered nose attached to the second longitudinal end of the non-boronized elongated body, the tapered nose formed of a metal base treated by a boronization process such that the tapered nose has a an outer layer that is hardened relative to an inner portion of the metal base.
    Type: Application
    Filed: February 13, 2013
    Publication date: August 14, 2014
    Applicant: Enduratech Manufacturing, LLC
    Inventors: Habib Skaff, Clayton Ross, Charles Paquette
  • Polymeric micelles for drug delivery
    Patent number: 8779008
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: July 15, 2014
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Kevin N. Sill, Habib Skaff, Rebecca Breitenkamp
  • IMMUNOTHERAPY FOR TREATMENT OF AMYLOID-RELATED DISORDERS USING ENCAPSULATED BETA-AMYLOID PEPTIDES
    Publication number: 20140170225
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to encapsulated peptides and uses thereof.
    Type: Application
    Filed: August 1, 2013
    Publication date: June 19, 2014
    Inventors: CHUANHAI CAO, XIAOYANG LIN, KURT BREITENKAMP, HABIB SKAFF, KEVIN N. SILL
  • Polymeric micelles for polynucleotide encapsulation
    Patent number: 8747904
    Abstract: The present invention provides micelles having a polynucleotide encapsulated therein, the micelle comprising copolymers comprising hydrophobic moieties in a cationic complexing block. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Grant
    Filed: August 21, 2012
    Date of Patent: June 10, 2014
    Assignee: Intezyne Technologies, Inc.
    Inventors: Janni Mirosevich, Gregoire Cardoen, Kevin N. Sill, Habib Skaff
  • Polymer micelles containing anthracyclines for the treatment of cancer
    Patent number: 8629186
    Abstract: The present invention provides micelles having an anthracycline encapsulated therein, the micelles comprising a multiblock copolymer. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Grant
    Filed: July 25, 2013
    Date of Patent: January 14, 2014
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kevin N. Sill, Habib Skaff, Jonathan Rios-Doris
  • Multi-block copolymers for the preparation of stabilized micelles
    Patent number: 8609146
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same. Compositions herein are useful for drug-delivery applications.
    Type: Grant
    Filed: September 17, 2012
    Date of Patent: December 17, 2013
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kevin Sill, Habib Skaff
  • Poly(ethylene glycol) containing chemically disparate endgroups
    Patent number: 8609857
    Abstract: The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
    Type: Grant
    Filed: May 14, 2012
    Date of Patent: December 17, 2013
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Kevin Sill, Habib Skaff
  • POLYMER MICELLES CONTAINING ANTHRACYCLINES FOR THE TREATMENT OF CANCER
    Publication number: 20130309277
    Abstract: The present invention provides micelles having an anthracycline encapsulated therein, the micelles comprising a multiblock copolymer. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Application
    Filed: July 25, 2013
    Publication date: November 21, 2013
    Applicant: Intezyne Technologies, Incorporated
    Inventors: Kevin N. Sill, Habib Skaff, Jonathan Rios-Doria
  • COVALENT MODIFICATION OF METAL SURFACES
    Publication number: 20130310912
    Abstract: The present invention provides modified metal surfaces, methods of preparing the same, and intermediates thereto. These materials are useful in a variety of applications including biomaterials.
    Type: Application
    Filed: July 22, 2013
    Publication date: November 21, 2013
    Applicant: Intezyne Technologies
    Inventors: Kurt Breitenkamp, Rebecca Breitenkamp, Kevin N. Sill, Habib Skaff
  • POLYMERIC MICELLES FOR POLYNUCLEOTIDE ENCAPSULATION
    Publication number: 20130266617
    Abstract: The present invention provides micelles having a polynucleotide encapsulated therein, the micelle comprising copolymers comprising hydrophobic moieties in a cationic complexing block. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Application
    Filed: August 21, 2012
    Publication date: October 10, 2013
    Applicant: Intezyne Technologies, Inc.
    Inventors: Janni Mirosevich, Gregoire Cardoen, Kevin N. Sill, Habib Skaff
  • Polymer micelles containing anthracylines for the treatment of cancer
    Patent number: 8524784
    Abstract: The present invention provides micelles having an anthracycline encapsulated therein, the micelles comprising a multiblock copolymer. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Grant
    Filed: October 29, 2010
    Date of Patent: September 3, 2013
    Assignee: Intezyne Technologies, Incorporated
    Inventors: Kevin N. Sill, Habib Skaff, Jonathan Rios-Doria
  • Polymer micelles containing anthracylines for the treatment of cancer
    Patent number: 8524783
    Abstract: The present invention provides micelles having an anthracycline encapsulated therein, the micelles comprising a multiblock copolymer. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Grant
    Filed: April 30, 2010
    Date of Patent: September 3, 2013
    Assignee: Intezyne Technologies, Incorporated
    Inventors: Kevin N. Sill, Habib Skaff, Jonathan Rios-Doria, Gregoire Cardoen
  • POLYMERIC MICELLES FOR DRUG DELIVERY
    Publication number: 20130195987
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Application
    Filed: December 19, 2012
    Publication date: August 1, 2013
    Applicant: INTEZYNE TECHNOLOGIES, INC.
    Inventors: Kurt Breitenkamp, Kevin N. Sill, Habib Skaff, Rebecca Breitenkamp
  • Polymeric micelles for drug delivery
    Patent number: 8426477
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Grant
    Filed: July 31, 2012
    Date of Patent: April 23, 2013
    Assignee: Intezyne Technologies, LLC
    Inventors: Kurt Breitenkamp, Kevin Sill, Habib Skaff, Rebecca Breitenkamp
  • Compositions comprising polymeric micelles for drug delivery
    Patent number: 8299128
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Grant
    Filed: December 7, 2010
    Date of Patent: October 30, 2012
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kevin N. Sill, Habib Skaff, Kurt Breitenkamp, Rebecca Breitenkamp
  • Polymeric micelles for polynucleotide encapsulation
    Patent number: 8287910
    Abstract: The present invention provides micelles having a polynucleotide encapsulated therein, the micelle comprising copolymers comprising hydrophobic moieties in a cationic complexing block. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Grant
    Filed: April 29, 2010
    Date of Patent: October 16, 2012
    Assignee: Intezyne Technologies, Inc.
    Inventors: Janni Mirosevich, Gregoire Cardoen, Kevin N. Sill, Habib Skaff
  • Azide functionalized peptide targeting groups
    Patent number: 8263663
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Grant
    Filed: December 7, 2010
    Date of Patent: September 11, 2012
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kevin N. Sill, Habib Skaff, Kurt Breitenkamp, Rebecca Breitenkamp
  • Polymeric micelles for drug delivery
    Patent number: 8263665
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Grant
    Filed: December 22, 2009
    Date of Patent: September 11, 2012
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kevin N. Sill, Habib Skaff, Kurt Breitenkamp, Rebecca Breitenkamp