Patents by Inventor Habib Skaff

Habib Skaff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLY(ETHYLENE GLYCOL) CONTAINING CHEMICALLY DISPARATE ENDGROUPS
    Publication number: 20120226050
    Abstract: The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
    Type: Application
    Filed: May 14, 2012
    Publication date: September 6, 2012
    Applicant: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Kevin N. Sill, Habib Skaff
  • Encapsulated contrast agents
    Patent number: 8258190
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to encapsulated contrast agents and methods for using the same.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: September 4, 2012
    Assignee: Intezyne Technologies, Inc.
    Inventors: Habib Skaff, Kurt Breitenkamp, Kevin N. Sill
  • Heterobifunctional poly(ethylene glycol) containing acid-labile amino protecting groups and uses thereof
    Patent number: 8212083
    Abstract: The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
    Type: Grant
    Filed: April 27, 2007
    Date of Patent: July 3, 2012
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Kevin N. Sill, Habib Skaff
  • Poly(ethylene glycol) containing chemically disparate endgroups
    Patent number: 8207353
    Abstract: The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
    Type: Grant
    Filed: February 17, 2010
    Date of Patent: June 26, 2012
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kevin N. Sill, Habib Skaff, Kurt Breitenkamp
  • MECHANICAL PARTS HAVING INCREASED WEAR-RESISTANCE
    Publication number: 20120052315
    Abstract: The present invention relates to wear-resistant mechanical parts.
    Type: Application
    Filed: September 1, 2011
    Publication date: March 1, 2012
    Applicant: SKAFF CORPORATION OF AMERICA, INC.
    Inventor: Habib Skaff
  • PLASMA MODIFICATION OF METAL SURFACES
    Publication number: 20120046735
    Abstract: The present invention provides modified metal surfaces, methods of preparing the same, and intermediates thereto. These materials are useful in a variety of applications including biomaterials.
    Type: Application
    Filed: January 14, 2011
    Publication date: February 23, 2012
    Applicant: Intezyne Technologies, Incorporated
    Inventors: Kevin N. Sill, Habib Skaff, Kurt Breitenkamp
  • COVALENT MODIFICATION OF METAL SURFACES
    Publication number: 20120046757
    Abstract: The present invention provides modified metal surfaces, methods of preparing the same, and intermediates thereto. These materials are useful in a variety of applications including biomaterials.
    Type: Application
    Filed: October 31, 2011
    Publication date: February 23, 2012
    Applicant: INTEZYNE TECHNOLOGIES
    Inventors: Kurt Breitenkamp, Rebecca Breitenkamp, Kevin N. Sill, Habib Skaff
  • Covalent modification of metal surfaces
    Patent number: 8066824
    Abstract: The present invention provides modified metal surfaces, methods of preparing the same, and intermediates thereto. These materials are useful in a variety of applications including biomaterials.
    Type: Grant
    Filed: July 9, 2007
    Date of Patent: November 29, 2011
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Rebecca Breitenkamp, Kevin N. Sill, Habib Skaff
  • Mechanical parts having increased wear-resistance
    Patent number: 8012274
    Abstract: The present invention relates to wear-resistant mechanical parts.
    Type: Grant
    Filed: March 21, 2008
    Date of Patent: September 6, 2011
    Assignee: Skaff Corporation of America, Inc.
    Inventor: Habib Skaff
  • POLYMER MICELLES CONTAINING ANTHRACYLINES FOR THE TREATMENT OF CANCER
    Publication number: 20110142950
    Abstract: The present invention provides micelles having an anthracycline encapsulated therein, the micelles comprising a multiblock copolymer. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Application
    Filed: October 29, 2010
    Publication date: June 16, 2011
    Applicant: INTEZYNE TECHNOLOGIES, INCORPORATED
    Inventors: Kevin N. Sill, Habib Skaff, Jonathan Rios-Doria
  • COMPOSITIONS COMPRISING POLYMERIC MICELLES FOR DRUG DELIVERY
    Publication number: 20110091534
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Application
    Filed: December 7, 2010
    Publication date: April 21, 2011
    Applicant: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Kevin N. Sill, Habib Skaff, Rebecca Breitenkamp
  • AZIDE FUNCTIONALIZED PEPTIDE TARGETING GROUPS
    Publication number: 20110092668
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Application
    Filed: December 7, 2010
    Publication date: April 21, 2011
    Applicant: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Kevin N. Sill, Habib Skaff, Rebecca Breitenkamp
  • Poly(ethylene glycol) containing chemically disparate endgroups
    Patent number: 7893277
    Abstract: The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
    Type: Grant
    Filed: May 29, 2009
    Date of Patent: February 22, 2011
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Kevin N. Sill, Habib Skaff
  • HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS
    Publication number: 20100324259
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Application
    Filed: September 1, 2010
    Publication date: December 23, 2010
    Applicant: Intezyne Technologies, Inc.
    Inventors: Kevin N. Sill, Habib Skaff, Kurt Breitenkamp
  • POLYMERS FOR POLYNUCLEOTIDE ENCAPSULATION
    Publication number: 20100292432
    Abstract: The present invention provides block copolymers comprising hydrophobic moieties in a cationic complexing block, methods of preparing the same, and intermediates thereto. The compounds are useful in a variety of applications such as the assembly of micellar polyion complexes. The invention further provides methods of using said compounds and compositions thereof.
    Type: Application
    Filed: April 29, 2010
    Publication date: November 18, 2010
    Applicant: Intezyne Technologies, Incorporated
    Inventors: Gregoire Cardoen, Kevin N. Sill, Janni Mirosevich, Habib Skaff
  • POLYMERIC MICELLES FOR POLYNUCLEOTIDE ENCAPSULATION
    Publication number: 20100278927
    Abstract: The present invention provides micelles having a polynucleotide encapsulated therein, the micelle comprising copolymers comprising hydrophobic moieties in a cationic complexing block. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Application
    Filed: April 29, 2010
    Publication date: November 4, 2010
    Applicant: Intezyne Technologies, Incorporated
    Inventors: Janni Mirosevich, Gregoire Cardoen, Kevin N. Sill, Habib Skaff
  • POLYMER MICELLES CONTAINING ANTHRACYLINES FOR THE TREATMENT OF CANCER
    Publication number: 20100278928
    Abstract: The present invention provides micelles having an anthracycline encapsulated therein, the micelles comprising a multiblock copolymer. The invention further provides methods of preparing and using said micelles, and compositions thereof.
    Type: Application
    Filed: April 30, 2010
    Publication date: November 4, 2010
    Applicant: Intezyne Technologies, Incorporated
    Inventors: Kevin N. Sill, Jonathan Rios-Doria, Habib Skaff, Gregoire Cardoen
  • POLY(ETHYLENE GLYCOL) CONTAINING CHEMICALLY DISPARATE ENDGROUPS
    Publication number: 20100280252
    Abstract: The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
    Type: Application
    Filed: February 17, 2010
    Publication date: November 4, 2010
    Applicant: Intezyne Technologies
    Inventors: Kurt Breitenkamp, Kevin N. Sill, Habib Skaff
  • POLYMER MICELLES CONTAINING SN-38 FOR THE TREATMENT OF CANCER
    Publication number: 20100278932
    Abstract: The present invention provides micelles having SN-38 encapsulated therein.
    Type: Application
    Filed: May 4, 2010
    Publication date: November 4, 2010
    Applicant: Intezyne Technologies, Incorporated
    Inventors: Kevin N. Sill, Habib Skaff, Adam Carie, Jonathan Rios-Doria, Richard Slama, Gregoire Cardoen
  • Hybrid block copolymer micelles with mixed stereochemistry for encapsulation of hydrophobic agents
    Patent number: 7799339
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: September 21, 2010
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kevin N. Sill, Habib Skaff, Kurt Breitenkamp