Patents by Inventor Habib Skaff

Habib Skaff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Plasma boriding method
    Patent number: 7767274
    Abstract: The present invention relates to a method of preparing wear-resistant metallic surfaces.
    Type: Grant
    Filed: September 21, 2006
    Date of Patent: August 3, 2010
    Assignee: Skaff Corporation of America
    Inventor: Habib Skaff
  • POLY(ETHYLENE GLYCOL) CONTAINING CHEMICALLY DISPARATE ENDGROUPS
    Publication number: 20100160645
    Abstract: The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
    Type: Application
    Filed: May 29, 2009
    Publication date: June 24, 2010
    Applicant: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Kevin N. Sill, Habib Skaff
  • POLYMERIC MICELLES FOR DRUG DELIVERY
    Publication number: 20100159020
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Application
    Filed: December 22, 2009
    Publication date: June 24, 2010
    Applicant: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Kevin N. Sill, Habib Skaff, Rebecca Breitenkamp
  • Immunotherapy for Treatment of Amyloid-Related Disorders Using Encapsulated Beta-Amyloid Peptides
    Publication number: 20100136063
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to encapsulated peptides and uses thereof.
    Type: Application
    Filed: November 16, 2009
    Publication date: June 3, 2010
    Applicants: UNIVERSITY OF SOUTH FLORIDA, INTEZYNE TECHNOLOGIES, INC.
    Inventors: CHUANHAI CAO, XIAOYANG LIN, KURT BREITENKAMP, HABIB SKAFF, KEVIN N. SILL
  • Polymeric micelles for drug delivery
    Patent number: 7638558
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Grant
    Filed: April 3, 2006
    Date of Patent: December 29, 2009
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Kevin N. Sill, Habib Skaff, Rebecca Breitenkamp
  • Encapsulated amyloid-beta peptides
    Patent number: 7618944
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to encapsulated peptides and uses thereof.
    Type: Grant
    Filed: February 29, 2008
    Date of Patent: November 17, 2009
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Habib Skaff, Kevin N. Sill
  • Quantum Dots Tailored with Electronically-Active Polymers
    Publication number: 20090275782
    Abstract: Cadmium selenide, and other quantum dot materials, can be integrated into thin films of poly(para-phenylene vinylene) (PPV) or other polymer compounds without aggregation of the nanocrystals. Solid-state photoluminescence spectra of composite materials prepared by these novel techniques reveal the effect of this greatly enhanced quantum dot-polymer interface relative to cases where the nanoparticles are aggregated, such that electronic communication and energy transfer between the nanoparticle and polymer components is made more efficient.
    Type: Application
    Filed: April 27, 2009
    Publication date: November 5, 2009
    Inventors: Todd S. Emrick, Habib Skaff, Kevin Sill
  • Heterobifunctional poly(ethylene glycol) and uses thereof
    Patent number: 7612153
    Abstract: The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
    Type: Grant
    Filed: October 24, 2005
    Date of Patent: November 3, 2009
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Kevin Sill, Habib Skaff
  • Quantum dots tailored with electronically-active polymers
    Patent number: 7589240
    Abstract: Cadmium selenide, and other quantum dot materials, can be integrated into thin films of poly(para-phenylene vinylene) (PPV) or other polymer compounds without aggregation of the nanocrystals. Solid-state photoluminescence spectra of composite materials prepared by these novel techniques reveal the effect of this greatly enhanced quantum dot-polymer interface relative to cases where the nanoparticles are aggregated, such that electronic communication and energy transfer between the nanoparticle and polymer components is made more efficient.
    Type: Grant
    Filed: August 8, 2005
    Date of Patent: September 15, 2009
    Assignee: University of Massachusetts
    Inventors: Todd S. Emrick, Habib Skaff, Kevin Sill
  • Pyridine and related ligand compounds, functionalized nanoparticulate composites and methods of preparation
    Patent number: 7563507
    Abstract: Nanoparticulate composites and dispersion thereof using novel polymeric ligand compounds, in certain embodiments in conjunction with pyridinyl moieties coupling the nanoparticulate and ligand.
    Type: Grant
    Filed: August 18, 2003
    Date of Patent: July 21, 2009
    Assignee: University of Massachusetts
    Inventors: Todd S. Emrick, Habib Skaff
  • Poly(ethylene glycol) containing chemically disparate endgroups
    Patent number: 7560588
    Abstract: The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
    Type: Grant
    Filed: April 27, 2007
    Date of Patent: July 14, 2009
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Kevin N. Sill, Habib Skaff
  • MODIFICATION OF BIOLOGICAL TARGETING GROUPS FOR THE TREATMENT OF CANCER
    Publication number: 20090110662
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to click-functionalized targeting compounds and methods for using the same.
    Type: Application
    Filed: April 30, 2008
    Publication date: April 30, 2009
    Applicant: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Jonathan Rios-Doria, Rebecca Breitenkamp, Kevin N. Sill, Habib Skaff
  • ENCAPSULATED CONTRAST AGENTS
    Publication number: 20090092554
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to encapsulated contrast agents and methods for using the same.
    Type: Application
    Filed: April 30, 2008
    Publication date: April 9, 2009
    Applicant: Intezyne Technologies, Inc.
    Inventors: Habib Skaff, Kurt Breitenkamp, Kevin N. Sill
  • Liquid-liquid interfacial nanoparticle assemblies
    Patent number: 7470840
    Abstract: Self-assembly of nanoparticles at the interface between two fluids, and methods to control such self-assembly process, e.g., the surface density of particles assembling at the interface; to utilize the assembled nanoparticles and their ligands in fabrication of capsules, where the elastic properties of the capsules can be varied from soft to tough; to develop capsules with well-defined porosities for ultimate use as delivery systems; and to develop chemistries whereby multiple ligands or ligands with multiple functionalities can be attached to the nanoparticles to promote the interfacial segregation and assembly of the nanoparticles. Certain embodiments use cadmium selenide (CdSe) nanoparticles, since the photoluminescence of the particles provides a convenient means by which the spatial location and organization of the particles can be probed. However, the systems and methodologies presented here are general and can, with suitable modification of the chemistries, be adapted to any type of nanoparticle.
    Type: Grant
    Filed: January 8, 2004
    Date of Patent: December 30, 2008
    Assignee: University of Massachusetts
    Inventors: Todd S. Emrick, Thomas P. Russell, Anthony Dinsmore, Habib Skaff, Yao Lin
  • ENCAPSULATED AMYLOID-BETA PEPTIDES
    Publication number: 20080274965
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to encapsulated peptides and uses thereof.
    Type: Application
    Filed: February 29, 2008
    Publication date: November 6, 2008
    Applicant: Intezyne Technologies, Inc.
    Inventors: Kurt Breitenkamp, Habib Skaff, Kevin N. Sill
  • HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS
    Publication number: 20080274173
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
    Type: Application
    Filed: April 30, 2008
    Publication date: November 6, 2008
    Applicant: Intezyne Technologies, Inc.
    Inventors: Kevin N. SILL, Habib Skaff, Kurt Breitenkamp
  • MECHANICAL PARTS HAVING INCREASED WEAR RESISTANCE
    Publication number: 20080233428
    Abstract: The present invention relates to wear-resistant mechanical parts.
    Type: Application
    Filed: March 21, 2008
    Publication date: September 25, 2008
    Applicant: Skaff Corporation of America, Inc.
    Inventor: Habib Skaff
  • Poly(ethylene glycol) containing chemically disparate endgroups
    Publication number: 20080207913
    Abstract: The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
    Type: Application
    Filed: April 27, 2007
    Publication date: August 28, 2008
    Applicant: Intezyne Technologies
    Inventors: Kurt Breitenkamp, Kevin N. Sill, Habib Skaff
  • Heterobifunctional poly(ethyleneglycol) containing acid-labile amino protecting groups and uses thereof
    Publication number: 20080188638
    Abstract: The present invention provides bifunctional polymers, methods of preparing the same, and intermediates thereto. These compounds are useful in a variety of applications including the PEGylation of biologically active molecules. The invention also provides methods of using said compounds and compositions thereof.
    Type: Application
    Filed: April 27, 2007
    Publication date: August 7, 2008
    Applicant: Intezyne Technologies
    Inventors: Kurt Breitenkamp, Kevin N. Sill, Habib Skaff
  • Covalent modification of metal surfaces
    Publication number: 20080035243
    Abstract: The present invention provides modified metal surfaces, methods of preparing the same, and intermediates thereto. These materials are useful in a variety of applications including biomaterials.
    Type: Application
    Filed: July 9, 2007
    Publication date: February 14, 2008
    Applicant: Intezyne Technologies
    Inventors: Kurt Breitenkamp, Rebecca Breitenkamp, Kevin Sill, Habib Skaff