Patents by Inventor Homme W. Hellinga

Homme W. Hellinga has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biosensor
    Patent number: 6521446
    Abstract: The present invention relates to a glucose biosensor comprising a genetically engineered Glucose Binding Protein (GBP). In a specific embodiment, the invention relates to a GBP engineered to include mutations that allow site specific introduction of environmentally sensitive reporter groups. The signal of these prosthetic groups changes linearly with the degree of glucose binding. Thus, the glucose sensor of the invention can be used, for example, for detection of glucose in blood or industrial fermentation processes.
    Type: Grant
    Filed: June 27, 2001
    Date of Patent: February 18, 2003
    Assignee: Duke University
    Inventor: Homme W. Hellinga
  • Biosensor
    Publication number: 20020004217
    Abstract: The present invention relates to a glucose biosensor comprising a genetically engineered Glucose Binding Protein (GBP). In a specific embodiment, the invention relates to a GBP engineered to include mutations that allow site specific introduction of environmentally sensitive reporter groups. The signal of these prosthetic groups changes linearly with the degree of glucose binding. Thus, the glucose sensor of the invention can be used, for example, for detection of glucose in blood or industrial fermentation processes.
    Type: Application
    Filed: June 27, 2001
    Publication date: January 10, 2002
    Applicant: DUKE UNIVERSITY
    Inventor: Homme W. Hellinga
  • Biosensor
    Patent number: 6277627
    Abstract: The present invention relates to a glucose biosensor comprising a genetically engineered Glucose Binding Protein (GBP). In a specific embodiment, the invention relates to a GBP engineered to include mutations that allow site specific introduction of environmentally sensitive reporter groups. The signal of these prosthetic groups changes linearly with the degree of glucose binding. Thus, the glucose sensor of the invention can be used, for example, for detection of glucose in blood or industrial fermentation processes.
    Type: Grant
    Filed: December 31, 1998
    Date of Patent: August 21, 2001
    Assignee: Duke University
    Inventor: Homme W. Hellinga