Abstract: Various exemplary drug delivery devices with a mechanical stop, drug products utilizing the same, and methods of using drug delivery devices with a mechanical stop are provided. In general, a nasal drug delivery device is configured to dispense therefrom first and second doses of a drug therefrom into a nose. The drug delivery device includes a mechanical stop configured to provide a pause between the delivery of the first and second doses. During the pause, a user of the drug delivery device can move the drug delivery device from one nostril, into which the first dose was sprayed, to another nostril, into which the second dose can be sprayed. The mechanical stop is configured to hold the drug delivery device in a static delivery state.

Abstract: A drug delivery device (400) comprises a tip (416) configured to be positioned in a nose of a patient, the tip having an opening (414) therein, a coupling mechanism (402) configured to releasably couple to a first vial (404) containing a first drug therein, to release the first vial therefrom, and to subsequently be releasably coupled to a second vial containing a second drug therein, and a plunger configured to be actuated to cause the first drug to exit through the opening and to be subsequently actuated to cause the second drug to exit through the opening. The same drug delivery device is therefore configured to deliver multiple doses. There are also disclosed various exemplary reloadable drug vials for multi-dose delivery, drug products utilizing the same, and methods of using reloadable drug vials for multi-dose delivery.

Abstract: A composite coating material for passive vibration damping is provided. The composite coating material includes a polymer matrix, and a piezoelectric ceramic filler and an electrically conductive filler dispersed in the polymer matrix. Particles of the piezoelectric ceramic filler have an average particle size of greater than about 100 microns (?m).

Abstract: Various exemplary drug syringes with a mechanical stop for a second dose, drug products utilizing the same, and methods of using drug syringes with a mechanical stop for a second dose are provided. In general, a nasal drug delivery device is configured to dispense therefrom first and second doses of a drug therefrom into a nose. The drug delivery device includes a mechanical stop configured to provide a pause between the delivery of the first and second doses. During the pause, a user of the drug delivery device can move the drug delivery device from one nostril, into which the first dose was sprayed, to another nostril, into which the second dose can be sprayed. The mechanical stop is configured to hold the drug delivery device in a static delivery state.

Abstract: Various exemplary drug holders (102, 200) for drug delivery devices (100), drug products utilizing the same, and methods of using drug holders for drug delivery devices are provided. In general, a nasal drug delivery device is configured to dispense therefrom at least one dose of a drug therefrom into a nose. The drug delivery device includes a drug holder that contains the drug therein that is delivered out of the drug delivery device. The drug holder can include two cavities (208, 210) therein that are fluidically sealed from one another prior to use of the drug delivery device to cause drug delivery. A first one of the cavities includes the drug therein, and a second one of the cavities includes a drug or air therein.

Abstract: Various exemplary drug delivery devices with multiple drug vials, drug products utilizing the same, and methods of using drug delivery devices with multiple drug vials are provided. In general, a nasal drug delivery device configured to dispense a drug therefrom into a nose and includes two or more vials each containing the drug therein. The drug delivery device is configured to deliver the drug from each of the vials for a total of two or more sprays into the nose. The same drug delivery device may therefore deliver multiple drug sprays to a user. In some embodiments, instead of including two or more vials that collectively contain enough drug therein for more than two drug sprays, the drug delivery device can include a single vial that contains enough drug therein for more than two drug sprays.

Abstract: A processing device in a memory system receives an erase request to erase data stored at a data block of a memory device, the erase request identifying a selected sub-block of a plurality of sub-blocks of the data block for erase, each of the plurality of sub-blocks comprising select gate devices (SGDs) and data storage devices. For each sub-block of the plurality of sub-blocks not selected for erase, the processing device applies an input voltage at a bitline of the respective sub-block and applies a plurality of gate voltages to a plurality of wordlines of the respective sub-block, the plurality of wordlines are coupled to the SGDs and to the data storage devices, each voltage of the plurality of voltages applied to a successive wordline of the plurality of wordlines is less than a previous voltage applied to a previous wordline.

Abstract: Control logic in a memory device initiates a program operation on the memory device, and causes a program voltage to be applied to a selected wordline of the memory array during a program phase of the program operation. The control logic further causes a select gate drain coupled with a string of memory cells in the memory array to deactivate during a recovery phase after applying the program voltage, wherein the string of memory cells comprises a plurality of memory cells, and wherein each memory cell of the plurality of memory cells is coupled to a corresponding wordline of a plurality of wordlines in the memory array.

Abstract: Various exemplary drug delivery devices with on-board drug destruction, drug products utilizing the same, and methods of using drug delivery devices with on-board drug destruction are provided. In general, a nasal drug delivery device configured to dispense a drug therefrom into a nose includes a destruction mechanism configured to destroy drug contained in the drug delivery device. The destruction mechanism can be configured to destroy the drug before a first actuation of the drug delivery device to deliver the drug therefrom such that the destruction mechanism destroys substantially all of the drug contained in the drug delivery device. Alternatively or in addition, the destruction mechanism can be configured to destroy the drug after a first actuation of the drug delivery device to deliver the drug therefrom such that the destruction mechanism destroys substantially all of the drug remaining in the drug delivery device.

Abstract: Use of a silane additive with carbon-carbon triple bond in an electrolyte for inhibiting the gas production of a cell, use of a combined additive of the silane additive and a film-forming additive in the electrolyte, use of a combined additive of the silane additive and a fluorine-containing lithium salt additive in the electrolyte, an electrolyte and a lithium ion battery containing the silane additive. The combined use of a silane additive and a film-forming additive and the combined use of a silane additive and a fluorine-containing lithium salt additive can not only inhibit the gas production of a cell and improve the high-temperature storage performance of a battery, but also improve the stability of the battery in a high-temperature cycle and a room temperature cycle.

Abstract: Control logic in a memory device cause a programming pulse to be applied to a set of wordlines including a first set of even-numbered wordlines corresponding to a first set of memory cells to be erased and a second set of odd-numbered wordlines corresponding to a second set of memory cells to be erased, where a set of electrons are injected into a first set of gate regions, a second set of gate regions, and a set of inter-cell regions of a charge trap (CT) layer of the memory device. The control logic executes a first erase cycle on the first set of even-numbered wordlines to remove a first subset of electrons from the first set of gate regions corresponding to the first set of even-numbered wordlines. The control logic executes a second erase cycle on the second set of odd-numbered wordlines to remove a second subset of electrons from the second set of gate regions corresponding to the second set of even-numbered wordlines.

Abstract: Control logic in a memory device initiates a program operation on the memory device, the program operation comprising a program phase, a program recovery phase, a program verify phase, and a program verify recovery phase. The control logic further causes a negative voltage signal to be applied to a first plurality of word lines of a data bock of the memory device during the program verify recovery phase of the program operation, wherein each of the first plurality of word lines is coupled to a corresponding memory cell of a first plurality of memory cells in a string of memory cells in the data block, the first plurality of word lines comprising a selected word line associated with the program operation and one or more data word lines adjacent to the selected word line.

Abstract: A performance prediction method and system for a whole atomization process of an aeroengine fuel. The method includes: establishing a physical fuel-gas-droplet multiphase flow model; obtaining a central velocity field and a fluid volume fraction distribution of meshes with a finite volume method (FVM) based on the physical fuel-gas-droplet multiphase flow model; defining a gas and a liquid according to the central velocity field and the fluid volume fraction distribution; performing mesh refinement on the gas-liquid two-phase interface with an orthogonal adaptive Cartesian mesh method; transforming droplets less than a specified size in the atomization process into Lagrangian particle points; and performing calculation on different volume fractions for the Lagrangian particles included in the meshes to obtain flow field data and droplet data on different time nodes.

Abstract: A package or a chip including a linear amplifier and a power amplifier is provided, wherein the linear amplifier is configured to receive an envelope tracking signal to generate an amplified envelope tracking signal, the power amplifier is supplied by an envelope tracking supply voltage comprising a DC supply voltage and the amplified envelope tracking signal, and the power amplifier is configured to receive an input signal to generate an output signal.

Abstract: A tensor processor comprising a processing element array, the array having a plurality of processing elements arranged to individually perform operations on variables of a tensor, wherein each of processing elements are individually controlled by a processing element controller to perform tensor operations on a tensor. The processing elements controller are controlled by a series of tensor operation modules to perform a specific tensor operation.

Abstract: Control logic in a memory device initiates, subsequent to a program verify phase of a program operation, a new program operation on the memory array, the new program operation comprising a pre-boosting phase occurring prior to a program phase. The control logic causing one or more positive pre-boosting voltages to be applied to corresponding subsets of a plurality of word lines of a block of the memory array during the pre-boosting phase and causes the one or more positive pre-boosting voltages to be ramped down to a ground voltage during the pre-boosting phase in a designated order based on a location of the corresponding subsets of the plurality of word lines to which the one or more positive pre-boosting voltages were applied.

Abstract: A method for generating a morphological atlas of an embryo including the steps of receiving a plurality of 3D images of the embryo representative of the morphological process of embryonic cells from a first predetermined cell population to a second predetermined cell population; processing the plurality of 3D images to derive nucleus lineage information associated with each nucleus of the embryonic cells during the morphological process; performing a membrane segmentation procedure to segment the 3D images into membrane segments; and combining the nucleus lineage information and the membrane segments to generate the morphological atlas of the embryo.

Abstract: The present disclosure provides a contact structure and an electronic device having the same. The contact structure includes a substrate, a copper layer, an organic composite protective layer, and a silver nanowire layer. The copper layer is disposed on the substrate. The nanowire-distribution-promotion layer is disposed between the copper layer and the silver nanowire layer.

Abstract: A system and method for determining a facial expression including a facial mask generator arranged to detect a plurality of facial points from one or more facial images to generate one or more associated facial point masks, arranged to represent the facial features of an associated face of the one or more facial images; and a learning network arranged to receive and input of the one or more facial images and the one or more associated facial point masks to obtain a classification result for each of the one or more facial images, wherein the classification result is one of a plurality of predefined facial expressions.

Abstract: A system and method for detecting a facial apparatus including a facial image processor arranged to process an image or a stream of images to detect a facial apparatus on one or more faces represented within the image or the stream of images; and generating a notification output based on a detection of the facial apparatus on the one or more faces.