Abstract: The present disclosure relates to a CMOS image sensor having a multiple deep trench isolation (MDTI) structure, and an associated method of formation. In some embodiments, a plurality of photodiodes is formed from a front-side of a substrate. A plurality of boundary deep trench isolation (BDTI) trenches having a first depth and a plurality of multiple deep trench isolation (MDTI) trenches having a second depth are formed from a back-side of the substrate. A stack of dielectric layers is formed in the BDTI trenches and the MDTI trenches. A plurality of color filters is formed overlying the stack of dielectric layers corresponding to the plurality of photodiodes.

Abstract: The present disclosure relates to a CMOS image sensor having a multiple deep trench isolation (MDTI) structure, and an associated method of formation. In some embodiments, a plurality of pixel regions is disposed within a substrate and respectively comprising a photodiode. The photodiode comprises a doped layer with a first doping type and an adjoining region of the substrate with a second doping type that is different than the first doping type. A boundary deep trench isolation (BDTI) structure is disposed between adjacent pixel regions. A multiple deep trench isolation (MDTI) structure overlies the doped layer of the photodiode. The MDTI structure comprises a stack of dielectric layers lining sidewalls of a MDTI trench. A plurality of color filters is disposed at the back-side of the substrate corresponding to the respective photodiode of the plurality of pixel regions and overlying the MDTI structure.

Abstract: Disclosed are imidazole and thiazole compounds, as well as pharmaceutical compositions and methods of use thereof. One embodiment is a compound having the structure and pharmaceutically acceptable salts, prodrugs and N-oxides thereof (and solvates and hydrates thereof), wherein X, A, Z, R1 and R? are as described herein. In certain embodiments, a compound disclosed herein inhibits TGF-?, and can be used to treat disease by blocking TGF-? signaling.

Abstract: The present disclosure relates to a CMOS image sensor having a multiple deep trench isolation (MDTI) structure, and an associated method of formation. In some embodiments, a plurality of pixel regions is disposed within a substrate and respectively comprising a photodiode. A boundary deep trench isolation (BDTI) structure is disposed between adjacent pixel regions, extending from a back-side of the substrate to a first depth within the substrate, and surrounding the photodiode. A multiple deep trench isolation (MDTI) structure is disposed within the individual pixel region, extending from the back-side of the substrate to a second depth within the substrate, and overlying the photodiode. A dielectric layer fills in a BDTI trench of the BDTI structure and a MDTI trench of the MDTI structure.

Abstract: The present disclosure relates to a CMOS image sensor having a multiple deep trench isolation (MDTI) structure, and an associated method of formation. In some embodiments, a plurality of pixel regions is disposed within a substrate and respectively comprising a photodiode. A boundary deep trench isolation (BDTI) structure is disposed between adjacent pixel regions, extending from a back-side of the substrate to a first depth within the substrate, and surrounding the photodiode. A multiple deep trench isolation (MDTI) structure is disposed within the individual pixel region, extending from the back-side of the substrate to a second depth within the substrate, and overlying the photodiode. A dielectric layer fills in a BDTI trench of the BDTI structure and a MDTI trench of the MDTI structure.

Abstract: Disclosed are imidazole and thiazole compounds, as well as pharmaceutical compositions and methods of use thereof. One embodiment is a compound having the structure and pharmaceutically acceptable salts, prodrugs and N-oxides thereof (and solvates and hydrates thereof), wherein X, A, Z, R1 and R? are as described herein. In certain embodiments, a compound disclosed herein inhibits TGF-?, and can be used to treat disease by blocking TGF-? signaling.

Abstract: Disclosed are imidazole and thiazole compounds, as well as pharmaceutical compositions and methods of use thereof. One embodiment is a compound having the structure and pharmaceutically acceptable salts, prodrugs and N-oxides thereof (and solvates and hydrates thereof), wherein X, A, Z, R1 and R? are as described herein. In certain embodiments, a compound disclosed herein inhibits TGF-?, and can be used to treat disease by blocking TGF-? signaling.

Abstract: The present disclosure provides a photovoltaic-photothermal reaction complementary full-spectrum solar utilization system, comprising: a waveband thermal reactor having a reactant flow channel and a reaction chamber therein, a photovoltaic cell attached to a surface of the waveband thermal reactor, and a full spectrum concentrator configured to concentrate full spectrum sunlight onto a surface of the photovoltaic cell, wherein the full spectrum concentrating device concentrates the full spectrum sunlight onto a upper surface of the opaque or transmissive photovoltaic cell, wherein a portion of the sunlight is converted into electric energy and another portion of the sunlight is converted into thermal energy, and wherein the thermal energy is utilized by the waveband thermal reactor to preheat reactant(s) in the reaction chamber and to make a portion of the reactant(s) to undergo an endothermic chemical reaction such that the thermal energy is stored as chemical energy.

Abstract: Disclosed are imidazole and thiazole compounds, as well as pharmaceutical compositions and methods of use thereof. One embodiment is a compound having the structure and pharmaceutically acceptable salts, prodrugs and N-oxides thereof (and solvates and hydrates thereof), wherein X, A, Z, R1 and R? are as described herein. In certain embodiments, a compound disclosed herein inhibits TGF-?, and can be used to treat disease by blocking TGF-? signaling.

Abstract: A pivoting mechanism, including a first bracket, a second bracket, at least one first crank, and at least one second crank, is provided. The first bracket connecting a first body of an electronic device has a first slot. The second bracket connecting a second body has a second slot. The first crank has a first end slidably and rotatably coupled to the first slot, a second end pivoted to the second bracket, and a first pivoting portion. The second crank has a third end slidably and rotatably coupled to the second slot, a fourth end pivoted to the first bracket, and a second pivoting portion. The first and second pivoting portions are connected to form a rotation center, such that the first and second cranks are rotated about the rotation center and the first and second ends slide in the first and second slots respectively.

Abstract: This invention is directed to methods of treating diseases or conditions associated with JAK2 activity in a mammal comprising the administration of a compound of formula (I): where n, m, Y, R1, R2, R3, R4 and R5 are disclosed herein, or a pharmaceutically acceptable salt.

Abstract: Disclosed herein is an electronic luggage locking device and airline baggage handling method mainly characterized by ease-of-use, enhanced security and efficiency by utilizing proximity access-gaining and authentication technologies, a plurality of sensors, embedded electronic storage and retrieval of luggage information. The luggage locking device is incorporated with an electronic communication system enables interactions with other sensor modules within the luggage, external smart devices and airline transport systems to form an unitary baggage handling system. The baggage handling system contents a method using application software and capable of indicating and communicating the said luggage information and locational identification within an airline transport systems.

Abstract: Disclosed herein is an electronic combination lock mainly characterized by miniature size and easy-to-use electronic identification access-gaining method that enables a vast variety and type of access codes for user setting and choice. Another battery operated electronic key unit, incorporated with programmed access code to provide as an alternative choice for locking, unlocking and backup power, can be used in conjunction with the electronic combination lock.

Abstract: Disclosed herein is an electronic luggage locking device and airline baggage handling method mainly characterized by ease-of-use, enhanced security and efficiency by utilizing proximity access-gaining and authentication technologies, a plurality of sensors, embedded electronic storage and retrieval of luggage information. The luggage locking device is incorporated with an electronic communication system enables interactions with other sensor modules within the luggage, external smart devices and airline transport systems to form an unitary baggage handling system. The baggage handling system contents a method using application software and capable of indicating and communicating the said luggage information and locational identification within an airline transport systems.

Abstract: Disclosed herein is an electronic luggage locking device and airline baggage handling method mainly characterized by ease-of-use, enhanced security and efficiency by utilizing proximity access-gaining and authentication technologies, a plurality of sensors, embedded electronic storage and retrieval of luggage information. The luggage locking device is incorporated with an electronic communication system enables interactions with other sensor modules within the luggage, external smart devices and airline transport systems to form an unitary baggage handling system. The baggage handling system contents a method using application software and capable of indicating and communicating the said luggage information and locational identification within an airline transport systems.

Abstract: The invention relates to a method for calibration of 2-axis high precision digital angle measurement device, particularly for initializing a planar angle measuring device and an apparatus to generate simultaneous two-dimensional resultant planar angles of full 360° rotation. The planar angle measurement device is, typically but not exclusively, used in concurrent two-dimensional angles leveling, setting and alignment tasks for precision machine setup in the fields of precision engineering and metrology applications.