Abstract: Disclosed are imidazole and thiazole compounds, as well as pharmaceutical compositions and methods of use thereof. One embodiment is a compound having the structure and pharmaceutically acceptable salts, prodrugs and N-oxides thereof (and solvates and hydrates thereof), wherein X, A, Z, R1 and R? are as described herein. In certain embodiments, a compound disclosed herein inhibits TGF-?, and can be used to treat disease by blocking TGF-? signaling.

Abstract: Provided is a photo active layer for a solar cell or a light emitting diode and a fabricating method thereof. The photo active layer is formed by alternately stacking silicon quantum dot layers in which a plurality of silicon quantum dots containing conductive type impurities are formed in a medium, which is a silicon compound, and conductive layers, which are polycrystalline silicon layers, containing the same conductive type impurities as those of the silicon quantum dots.

Abstract: Disclosed are carboxamide compounds, as well as pharmaceutical compositions and methods of use. One embodiment is a compound having the structure in which R1, R2, R3, R4, D, J, Z, T, p, q, w and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.

Abstract: Disclosed are carboxamide compounds, as well as pharmaceutical compositions and methods of use. One embodiment is a compound having the structure in which R1, R2, R3, R4, D, J, Z, T, p, q, w and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.

Abstract: The present invention provides a distributed combined cooling, heating and power generating apparatus with an internal combustion engine by combining solar energy and alternative fuel and a method thereof, the apparatus comprising: an energy storage system for combined reaction between solar energy and alternative fuel, a solar fuel internal combustion engine generating system, a lithium bromide refrigeration system for absorbing exhaust heat of flue gas of solar fuel, a reaction device for recovering exhaust heat of flue gas, a heat exchanger for recovering exhaust heat of exhaust gas and a cylinder jacket and water plate heat exchanger.

Abstract: The present invention provides a power generating system by combining medium-and-low temperature solar energy and fossil fuel with thermochemical process, the system comprising: a material supply device configured to store fossil fuel; a material mixing device configured to mix the fossil fuel with non-reacted reactant; a material metering device configured to control an amount of material fed to a material preheating device in unit time; a material preheating device configured to heat the material; a solar energy absorption and reaction device configured to drive the fossil fuel by using solar thermal energy absorbed to make a decomposition reaction or reforming reaction, through which the solar energy is converted to chemical energy of hydrogen-rich fuel, obtaining solar-energy fuel; a solar energy heat collecting device configured to collect the solar energy with low energy flux density to medium-and-low temperature solar thermal energy with high energy flux density, so as to provide heat to decomposition

Abstract: Disclosed are carboxamide compounds, as well as pharmaceutical compositions and methods of use. One embodiment is a compound having the structure in which R1, R2, R3, R4, D, J, Z, T, p, q, w and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.

Abstract: The present invention provides N-substituted-heterocycloalkyloxybenzamide compounds, as well as pharmaceutical compositions and methods of use. One embodiment of the invention is a compound having the structure in which R1, R2, R3, R4, T, n, w and x are as described herein. In certain embodiments of the invention, a compound of the present invention activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.

Abstract: Disclosed are carboxamide, sulfonamide and amine compounds including certain AMPK-activating piperidinylxoy-substituted 2,3-dihydro-1H-indene-1-amine compounds, as well as pharmaceutical compositions including them. One embodiment is a compound having the structure in which R1, R3,R4,R5,R14,R15,R17, G, Q, k, v, x and y are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.

Abstract: Disclosed herein is an electronic combination lock mainly characterized by miniature size and easy-to-use electronic identification access-gaining method that enables a vast variety and type of access codes for user setting and choice. Another battery operated electronic key unit, incorporated with programmed access code to provide as an alternative choice for locking, unlocking and backup power, can be used in conjunction with the electronic combination lock.

Abstract: Disclosed are carboxamide compounds, as well as pharmaceutical compositions and methods of use. One embodiment is a compound having the structure in which R1, R2, R3, R4, D, J, Z, T, p, q, w and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.

Abstract: Disclosed are carboxamide compounds, as well as pharmaceutical compositions and methods of use. One embodiment is a compound having the structure in which R1, R2, R3, R4, D, J, Z, T, p, q, w and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.

Abstract: Disclosed are carboxamide compounds, as well as pharmaceutical compositions and methods of use. One embodiment is a compound having the structure in which R1, R2, R3, R4, D, J, Z, T, p, q, w and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.

Abstract: The present invention provides a power generating system by combining medium-and-low temperature solar energy and fossil fuel with thermochemical process, the system comprising: a material supply device configured to store fossil fuel; a material mixing device configured to mix the fossil fuel with non-reacted reactant; a material metering device configured to control an amount of material fed to a material preheating device in unit time; a material preheating device configured to heat the material; a solar energy absorption and reaction device configured to drive the fossil fuel by using solar thermal energy absorbed to make a decomposition reaction or reforming reaction, through which the solar energy is converted to chemical energy of hydrogen-rich fuel, obtaining solar-energy fuel; a solar energy heat collecting device configured to collect the solar energy with low energy flux density to medium-and-low temperature solar thermal energy with high energy flux density, so as to provide heat to decomposition

Abstract: The invention relates to a method for calibration of 2-axis high precision digital angle measurement device, particularly for initializing a planar angle measuring device and an apparatus to generate simultaneous two-dimensional resultant planar angles of full 360° rotation. The planar angle measurement device is, typically but not exclusively, used in concurrent two-dimensional angles leveling, setting and alignment tasks for precision machine setup in the fields of precision engineering and metrology applications.

Abstract: Disclosed are carboxamide, sulfonamide and amine compounds, as well as pharmaceutical compositions and methods of use. One embodiment is a compound having the structure in which R1, R2, R4, D, E, J, T, p, q and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.

Abstract: The present invention provides a distributed combined cooling, heating and power generating apparatus with an internal combustion engine by combining solar energy and alternative fuel and a method thereof, the apparatus comprising: an energy storage system for combined reaction between solar energy and alternative fuel, a solar fuel internal combustion engine generating system, a lithium bromide refrigeration system for absorbing exhaust heat of flue gas of solar fuel, a reaction device for recovering exhaust heat of flue gas, a heat exchanger for recovering exhaust heat of exhaust gas and a cylinder jacket and water plate heat exchanger.

Abstract: Disclosed are carboxamide compounds, as well as pharmaceutical compositions and methods of use. One embodiment is a compound having the structure in which R1, R2, R3, R4, D, J, Z, T, p, q, w and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.