Abstract: Methods for treating eye diseases associated with inflammation and/or vascular proliferation in subjects are disclosed. The methods include administering therapeutically effective amounts of a tranilast compound, in particular (E)-2-[[3-(3-Methoxy-4-propargyloxy)phenyl)-1-oxo-2-propenyl]amino]benzoic acid or (E)-2-[[3,4-Bis(difluoromethoxy)phenyl)-1-oxo-2-propenyl]amino]benzoic acid or pharmaceutically acceptable salts or solvates thereof.

Abstract: A multimode optical waveguide network comprises a parent waveguide and a plurality of child waveguides. Each waveguide is a multimode optical waveguide having a first surface region, multiple second surface regions, and at least one guiding element attached to a surface of the waveguide or embedded within the waveguide, each second surface region of the parent waveguide optically coupled to the first surface region of a corresponding child waveguide. The guiding element(s) of the parent waveguide is arranged to guide a beam, from or to its first surface region, to or from any selected second surface region of its multiple second surface regions. The guiding element(s) of each of the waveguides is configurable for selecting the second surface region of that waveguide and/or responsive to at least one beam characteristic for selecting the second surface region of that waveguide via modulation of the at least one beam characteristic.

Abstract: A wireless data transmission apparatus is disclosed, comprising one or more antennas for transmitting data as polarised electromagnetic radiation, and polarisation control means for controlling an axial ratio and a tilt angle of the polarised electromagnetic radiation such that the axial ratio and tilt angle conveys information about the data being transmitted. A corresponding wireless data receiving apparatus is also disclosed. In some embodiments, the one or more antennas comprises a patch antenna, and the polarisation means may comprise a mechanism for varying an electrical length of the angled slot. By utilising the tilt angle and axial ratio of polarised electromagnetic radiation to convey information to the receiver, the spectral efficiency of the system can be increased. A further increase in spectral efficiency may be obtained by using the polarisation control means to modulate first and second carrier waves, and transmitting different data on the first and second carrier waves.

Abstract: Embodiments of the disclosure are directed to methods, apparatuses, computer-readable media, and systems for network monitoring of communication requests for authorization to an access device. One embodiment is directed at dual message model in a distributed environment with an electronic access device receiving a cancellation signal and generating and sending a reversal message with cancellation information embedded in the data elements of the reversal message to a processor computer, where the cancellation data may be read and saved by the processor computer before the authorization request message is forwarded to be authorized by an authorization entity. The method further comprises generating a cancellation message after the reversal message has processed, where the cancellation message is sent via a transport computer to clear and reconcile the authorization status of the cancelled authorization request with any necessary authorizing or regulatory entities in the network.

Abstract: A humeral anchor for a shoulder prosthesis is disclosed. The humeral anchor includes a distal portion configured to be anchored in a proximal region of a humerus and a proximal portion, the proximal portion including a proximal face, where the proximal face includes an engagement feature configured to directly couple to a reverse shoulder insert having a concave proximal portion, and wherein the proximal face is further configured to directly couple with an anatomical shoulder insert having a convex proximal portion.

Abstract: A system for detecting impacts includes a housing configured to be worn by a user. An accelerometer is connected with the housing. The accelerometer is configured to detect an acceleration indicative of an impact experienced by the user. An inaudible tone chip is positioned about the housing. The inaudible tone chip is configured to transmit ultrasonic tones including data of the impact to a remote device. A remote device includes a receiver.

Abstract: The present technology provides compounds as well as compositions including such compounds useful in targeted radiotherapy of cancer and/or mammalian tissue overexpressing prostate specific membrane antigen (“PSMA”) where the compounds are represented by the following: or a pharmaceutical y acceptable salt thereof, or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, wherein M1 is independently at each occurrence an alpha-emitting radionuclide. Equivalents of such compounds are also disclosed.

Abstract: A system and method for recording video healthcare information of an individual under care without deleting data, includes a device for capturing data and configured to transmit a signal identifying the device, a memory for storing rules, a buffer, a database; and a processor. The processor receives the device identification signal and said data, and retrieves the rules from the memory. Based on the rules, the processor determines, whether the data is to be stored in the database or the buffer. Based on the content of the data, the processor determines the device location, the data recordation time and date, whether the individual under care is identified, and the individual's activity, and based on the rules and the location, time and date, individual identification, and activity, whether the data is proof of service delivery data to be stored in the database or eliminated from the buffer.

Abstract: The present disclosure relates generally to methods and devices for the cooling (or removal of heat from) power electronics modules in automotive vehicles, wherein the cooling is done by positioning the power electronics module in a housing, directing a fluid into the housing, and impinging the fluid onto the power electronics module and/or an electrical connection in contact with the power electronics module.

Abstract: Methods and apparatus for controlling two or more vehicles travelling in formation. Selected vehicles may be fully or partially autonomously controlled; at least one vehicle is partially controlled by a human driver. Information is collected at each vehicle and from the drivers and it is shared with other vehicles and drivers to create a shared world model. Aspects of the shared world model may be presented to the human driver, who may then respond with a control input. Autonomy systems and the drivers on the vehicles then collaborate to make a collective decision to act or not to act and execute any such action in a coordinated manner.

Abstract: Methods and apparatus for controlling two or more vehicles travelling in formation. Selected vehicles may be fully or partially autonomously controlled; at least one vehicle is partially controlled by a human driver. Information is collected at each vehicle and from the drivers and it is shared with other vehicles and drivers to create a shared world model. Aspects of the shared world model may be presented to the human driver, who may then respond with a control input. Autonomy systems and the drivers on the vehicles then collaborate to make a collective decision to act or not to act and execute any such action in a coordinated manner.

Abstract: The present technology provides compounds as well as compositions including such compounds useful in targeted radiotherapy of cancer and/or mammalian tissue overexpressing prostate specific membrane antigen (“PSMA”) where the compounds are represented by the following: or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, wherein M1 is independently at each occurrence an alpha-emitting radionuclide. Equivalents of such compounds are also disclosed.

Abstract: An impact absorbing apparatus includes a first chamber including a first chamber wall and a first valve disposed in the first chamber wall. The impact absorbing apparatus includes a second chamber including a second chamber wall and a second valve disposed in the second chamber wall. A plurality of connecting pillars connects the first chamber to the second chamber. The plurality of connecting pillars is configured to shift position in response to a first impact. The first valve is configured to pass air in and out of the first chamber. The second valve is configured to pass air in and out of the second chamber.

Abstract: The present technology provides compounds as well as compositions including such compounds useful in targeted radiotherapy of cancer and/or mammalian tissue overexpressing prostate specific membrane antigen (“PSMA”) where the compounds are represented by the following: or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, wherein M1 is independently at each occurrence an alpha-emitting radionuclide. Equivalents of such compounds are also disclosed.

Abstract: A system for detecting impacts includes a housing configured to be worn by a user. An accelerometer is connected with the housing. The accelerometer is configured to detect an acceleration indicative of an impact experienced by the user. An inaudible tone chip is positioned about the housing. The inaudible tone chip is configured to transmit ultrasonic tones including data of the impact to a remote device. A remote device includes a receiver. The receiver is configured to receive the ultrasonic tones transmitted by the inaudible tone chip.

Abstract: A humeral anchor for a shoulder prosthesis is disclosed. The humeral anchor includes a distal portion configured to be anchored in a proximal region of a humerus and a proximal portion, the proximal portion including a proximal face, where the proximal face includes an engagement feature configured to directly couple to a reverse shoulder insert having a concave proximal portion, and wherein the proximal face is further configured to directly couple with an anatomical shoulder insert having a convex proximal portion.

Abstract: Techniques are provided herein for generating PWM signals. Furthermore, a direct-drive method is disclosed in which a PWM signal is generated as a differential signal made up of OUTP and OUTN signals, where OUTP is a copy of OUTN but shifted in time by half a period. The PWM signal is generated by passing each of an input period and an input duty cycle through corresponding sigma-delta circuits to generate a refined period and a refined duty cycle, respectively. In some example cases, a threshold mapper uses a lookup table (LUT) or similar mechanism to select timing thresholds for rise times and fall times for each of the OUTP and OUTN signals, where the timing thresholds are selected based on the refined period and the refined duty cycle. In some example cases, a pulse generator generates the OUTP and OUTN signals based on the timing thresholds.

Abstract: Disclosed herein are methods and compositions related to improved coagulation factor complexes comprising factor VIII with a long half life. Disclosed herein is a coagulation factor complex comprising a factor VIII (FVIII) coagulation factor; a fusion protein comprising a D?D3 domain of von Willebrand's factor fused to full length albumin, or an albumin fragment; and an amino acid linker, in particular a cleavable amino acid linker.

Abstract: A system and method for recording video healthcare information of an individual under care based on properties of the information without deleting data, includes a device for capturing data relating to an individual, and configured to transmit a signal identifying the device, a memory for storing rules relating to the device, a buffer, a database; and a processor. The processor receives the device identification signal and said data, and retrieves the rules from the memory. Based on the rules, the processor determines, whether the data is to be stored in the database; or stored in the buffer. Based on the content of the data, the processor determines the location of the device, the time that the data was recorded, whether the individual recorded is identified as the individual under care, and the activity performed by the individual.

Abstract: An anti-wicking, scent-controlled, anti-microbial fabric is disclosed. Such anti-wicking, scent-controlled, anti-microbial fabric may be used to manufacture special occasion dresses, including wedding dresses and bridesmaid dresses. Also disclosed is a method of making a garment comprising an inner layer and an outer layer, using the anti-wicking, scent-controlled, anti-microbial fabric of the present invention.