Patents by Inventor Jean Simon

Jean Simon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11517598
    Abstract: Provided herein are methods for enhancing infection, growth, spread, or titer of an oncolytic RNA virus in a cancer or tumor cell; enhancing the oncolytic activity, cytokine-induced cell death activity, and/or cytotoxic activity of an oncolytic RNA virus in a cancer or tumor cell; upregulating cytokine response to, and/or enhancing the immunotherapeutic activity of an oncolytic RNA virus in a cancer or tumor cell; and/or treating a tumor or cancer in a subject in need thereof. Such methods employ a vanadium-containing compound, administered to the cancer or tumor cells before, after, or concurrently with infection of the cancer or tumor cells with the oncolytic RNA virus. Related compositions, uses, and kits therefor are also provided. Methods for producing RNA viruses, RNA virus-based cancer vaccines, and RNA virus-based cancer gene therapy vectors are also provided.
    Type: Grant
    Filed: October 3, 2017
    Date of Patent: December 6, 2022
    Assignee: Ottawa Hospital Research Institute
    Inventors: Mohammed Selman, Jean-Simon Diallo
  • Publication number: 20220319018
    Abstract: A computing device stores a predictive model generated by a neural network training engine. The computing device receives first and second two-dimensional (2D) thermal images comprising temperature measurements from respective first and second infrared (IR) sensors. The first and second images have the same size. An image capturing visual field of the second IR sensor partially overlaps with an image capturing visual field of the first IR sensor. The computing device executes a neural network using a predictive model for generating outputs based on inputs. The inputs comprise the temperature measurements of the first and second images. The outputs comprise horizontal and vertical shifts defining a translation of the second image with respect to the first image. An overlapping area in the first image, having a rectangular shape and overlapping with the second image, is determined using the horizontal and vertical shifts.
    Type: Application
    Filed: March 30, 2021
    Publication date: October 6, 2022
    Inventors: Francois GERVAIS, Jean-Simon BOUCHER, Simon-Pierre ALLAIRE, Josh AMELIA
  • Patent number: 11450463
    Abstract: A programmable permanent magnet actuator, a magnetic field generation apparatus and a method of controlling thereof. The actuator has a first body that is a ferromagnetic material, a second body that is a single magnetized ferromagnet and a magnetic field generation device associable to the second body to generate a magnetic field in proximity with the second body. The actuator also has a controller adapted to control the magnetic field generation device to generate a controlled magnetic field. The controlled magnetic field is adapted to modify a magnetization of the second body such as to produce with the second body a required magnetic field to move one of the first or the second body with respect to one another according to a desired position or a desired torque. The desired position or the desired torque is maintained even after the application of the controlled magnetic field.
    Type: Grant
    Filed: February 1, 2019
    Date of Patent: September 20, 2022
    Inventors: Jean-Baptiste Chossat, Vincent Duchaine, Jean-Simon Lavertu
  • Patent number: 11428432
    Abstract: A method and computing device for inferring an airflow of a controlled appliance operating in an area of a building. The computing device stores a predictive model. The computing device determines a measured airflow of the controlled appliance and a plurality of consecutive temperature measurements in the area. The computing device executes a neural network inference engine using the predictive model for inferring an inferred airflow based on inputs. The inputs comprise the measured airflow and the plurality of consecutive temperature measurements. The inputs may further include at least one of a plurality of consecutive humidity level measurements in the area and a plurality of consecutive carbon dioxide (CO2) level measurements in the area. For instance, the controlled appliance is a Variable Air Volume (VAV) appliance and a K factor of the VAV appliance is calculated based on the inferred airflow.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: August 30, 2022
    Assignee: Distech Controls Inc.
    Inventors: Francois Gervais, Dominique Laplante, Carlo Masciovecchio, Jean-Simon Boucher
  • Publication number: 20220261592
    Abstract: Method and computing device using a neural network to determine whether or not to process images of an image flow. A predictive model of the neural network is generated and stored at a computing device. The computing device receives (b) an image of the image flow and executes (c) the neural network, using the predictive model for generating an indication of whether or not to process the image based on input(s) of the neural network, the input(s) comprising the image. The computing device determines (d) whether or not to process the image by an image processing module, based on the indication of whether or not to process the image. The image is processed by the image processing module if the determination is positive and not processed if the determination is negative. Steps (b), (c), (d) are repeated for consecutive images of the image flow.
    Type: Application
    Filed: February 12, 2021
    Publication date: August 18, 2022
    Inventors: Jean-Simon BOUCHER, Francois GERVAIS
  • Publication number: 20220222535
    Abstract: Method and computing device using a neural network to analyze temperature measurements of an infrared sensor. A predictive model of the neural network is stored by the computing device. The computing device receives a two-dimensional (2D) matrix of temperature measurements generated by the IR sensor, and executes the neural network using the predictive model for generating outputs based on inputs. The inputs comprise the 2D matrix of temperature measurements. The outputs comprise a 2D matrix of inferred temperatures. The computing device determines a subset of values of the 2D matrix of temperature measurements, and applies a comparison algorithm to the subset of values of the 2D matrix of temperature measurements and a corresponding subset of values of the 2D matrix of inferred temperatures, to detect an anomaly in the subset of values of the 2D matrix of temperature measurements. A method for training the neural network is also provided.
    Type: Application
    Filed: January 8, 2021
    Publication date: July 14, 2022
    Inventors: Francois GERVAIS, Jean-Simon BOUCHER
  • Publication number: 20220220101
    Abstract: Provided are compounds that enhance the efficacy of viruses by increasing spread of the virus in cells, increasing the titer of virus in cells, or increasing the antigen expression from a virus, gene or trans-gene expression from a virus, or virus protein expression in cells. Other uses, compositions and methods of using same are also provided.
    Type: Application
    Filed: March 31, 2022
    Publication date: July 14, 2022
    Applicants: Ottawa Hospital Research Institute, University of Ottawa
    Inventors: Jean-Simon Diallo, Christopher Noyce Boddy, Mark Dornan, Ramya Krishnan, Rozanne Arulanandam, Fabrice Le Boeuf, Jeffrey Smith, Andrew Macklin
  • Patent number: 11364960
    Abstract: A vehicle comprises a chassis, a seat, a motor, an endless drive track, and a rear suspension assembly supporting the endless drive track. The rear suspension assembly includes a left slide and right slide rail, at least one rear suspension arm being operatively pivotally connected to one of the slide rails and the chassis, with at least one coupling block being connected thereto. A rear stopper is connected to one of the slide rails, the rear stopper being disposed within a range of motion of the at least one coupling block in a first position and being disposed out of the range of motion of the at least one coupling block in a second position. The vehicle includes a control cable and an actuator, the rear stopper moving between the first and second positions when moving the actuator between first and second actuator positions.
    Type: Grant
    Filed: September 26, 2017
    Date of Patent: June 21, 2022
    Assignee: BOMBARDIER RECREATIONAL PRODUCTS INC.
    Inventors: Jean-Simon Lavallee, Michel Bourassa
  • Publication number: 20220188640
    Abstract: Method and computing device using a neural network to bypass calibration data of an infrared sensor. A predictive model generated by a neural network training engine is stored by the computing device. The computing device determines a two-dimensional (2D) matrix of raw sensor data. Each raw sensor datum is representative of heat energy collected by the infrared sensor. The computing device executes a neural network inference engine. The neural network inference engine implements the neural network using the predictive model for generating outputs based on inputs. The inputs comprise the 2D matrix of raw sensor data. The outputs comprise a 2D matrix of inferred temperatures. A method for training a neural network to bypass calibration data of an infrared sensor is also provided.
    Type: Application
    Filed: December 11, 2020
    Publication date: June 16, 2022
    Inventors: Francois GERVAIS, Jean-Simon BOUCHER
  • Patent number: 11339146
    Abstract: Provided are compounds of Formula (II) that enhance the efficacy of viruses by increasing spread of the virus in cells, increasing the titer of virus in cells, or increasing the antigen expression from a virus, gene or trans-gene expression from a virus, or virus protein expression in cells. Other uses, compositions and methods of using same are also provided.
    Type: Grant
    Filed: May 18, 2020
    Date of Patent: May 24, 2022
    Assignee: Ottawa Hospital Research Institute and University of Ottawa
    Inventors: Jean-Simon Diallo, Christopher Noyce Boddy, Mark Dornan, Ramya Krishnan, Rozanne Arulanandam, Fabrice Le Boeuf, Jeffrey Smith, Andrew Macklin
  • Publication number: 20220128957
    Abstract: Device and method using a neural network to detect and compensate an air vacuum effect. The device stores a predictive model comprising weights of a neural network. The device receives an area temperature measurement (representative of a temperature of an area where the device is located) from a temperature sensing module of the device. The device determines at least one other measurement related to the device. The device executes a neural network inference engine implementing a neural network, using the predictive model for inferring output(s) based on inputs. The inputs comprise the area temperature measurement and the at least one other measurement related to the device. The output(s) comprises a metric representative of an air vacuum effect in the device. The device determines if an adjustment of the area temperature measurement needs to be performed based on the metric representative of the air vacuum effect in the device.
    Type: Application
    Filed: October 28, 2020
    Publication date: April 28, 2022
    Inventor: Jean-Simon BOUCHER
  • Patent number: 11297891
    Abstract: A helmet including a visor assembly having a breath guard is provided. The visor assembly includes a visor pivotally connected to the helmet shell and having an inner surface facing the cavity when in the lowered position. The visor assembly further includes a breath guard interface provided below the visor and a breath guard which has a visor interface connected to the breath guard interface of the visor assembly. The breath guard includes a flexible member connected to and extending from the visor interface and a contact surface shaped and configured to engage the wearer's face around the nose and mouth for deflecting humid air away from the inner surface of the visor. The flexible member has a channel extending along the visor interface having a substantially V-shaped cross-section configured to allow the flexible member to be deformed when raising the visor.
    Type: Grant
    Filed: February 21, 2020
    Date of Patent: April 12, 2022
    Assignee: KIMPEX INC.
    Inventors: Jean-Simon Levesque, Nicolas Bouchard Fortin, Stephane Dion, Étienne Gilbert
  • Publication number: 20220061449
    Abstract: A ventilated helmet is provided. The helmet includes a shell defining a cavity, the shell having a front section provided with an opening to allow the wearer to see. The helmet also includes a transparent shield adapted having an inner surface and being adapted to substantially close the opening. Finally, the helmet includes a ventilation system having an evacuation subsystem adapted to create an evacuation airflow to evacuate humid air within the cavity to a surrounding environment. The ventilation system further has a pressurizing subsystem adapted to admit a pressurizing airflow within the cavity to create a high-pressure zone and a low-pressure zone within the cavity, wherein when in use, the wearer exhales air within the low-pressure zone, and wherein the high-pressure zone prevents air within the cavity from travelling from the low-pressure zone to the high-pressure zone. A method of evacuating humid air from the cavity is also provided.
    Type: Application
    Filed: November 12, 2021
    Publication date: March 3, 2022
    Inventors: Nicolas BOUCHARD-FORTIN, Robert HANDFIELD, Jean-Simon LÉVESQUE, Étienne GILBERT, Hachimi FELLOUAH, Marouen DGHIM
  • Patent number: 11235634
    Abstract: A vehicle comprises a chassis, a seat, an endless drive track, a rear suspension assembly with at least one slide rail and a substantially inextensible limiter strap extending between the chassis and the at least one slide rail, to limit separation between the at least one slide rail and the chassis. The strap holder is moveable between a first holder position and a second holder position, a position of the end of the limiter strap being different in the first strap holder position compared to the second strap holder position. A control cable is operatively connects the strap holder to a strap adjustment actuator. The strap adjustment actuator is disposed forward of the seat and is operable by a user during operation of the vehicle, the strap adjustment actuator being movable between first and second positions related to the positions of the strap holder.
    Type: Grant
    Filed: September 26, 2017
    Date of Patent: February 1, 2022
    Assignee: BOMBARDIER RECREATIONAL PRODUCTS INC.
    Inventors: Jean-Simon Lavallee, Michel Bourassa
  • Patent number: 11202482
    Abstract: A ventilated helmet is provided. The helmet includes a shell defining a cavity, the shell having a front section provided with an opening to allow the wearer to see. The helmet also includes a transparent shield adapted having an inner surface and being adapted to substantially close the opening. Finally, the helmet includes a ventilation system having an evacuation subsystem adapted to create an evacuation airflow to evacuate humid air within the cavity to a surrounding environment. The ventilation system further has a pressurizing subsystem adapted to admit a pressurizing airflow within the cavity to create a high-pressure zone and a low-pressure zone within the cavity, wherein when in use, the wearer exhales air within the low-pressure zone, and wherein the high-pressure zone prevents air within the cavity from travelling from the low-pressure zone to the high-pressure zone. A method of evacuating humid air from the cavity is also provided.
    Type: Grant
    Filed: April 18, 2018
    Date of Patent: December 21, 2021
    Assignee: KIMPEX INC.
    Inventors: Nicolas Bouchard Fortin, Robert Handfield, Jean-Simon Lévesque, Étienne Gilbert, Hachimi Fellouah, Marouen Dghim
  • Patent number: 11098054
    Abstract: Disclosed is a compound of formula (I) in which a, R1-R5 and X1 are as described herein. Also disclosed are a pharmaceutical composition containing the compound and a method of using the compound for treating cancer, such as renal cancer.
    Type: Grant
    Filed: July 5, 2018
    Date of Patent: August 24, 2021
    Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Sciences, Fundacio Institut Catala D'Investigacio Quimica, University of Delaware, University of Leeds, Universitat Rovira I Virgili
    Inventors: John A. Beutler, Antonio Echavarren, William Chain, David Beech, Zhenhua Wu, Jean-Simon Suppo, Fernando Bravo, Hussein Rubaiy
  • Publication number: 20210205436
    Abstract: A recombinant attenuated Mopeia virus (MOPV) comprising a recombinant genomic S segment that encodes a nucleoprotein having attenuated exonuclease activity, and optionally further encodes a non-MOPV arenavirus glycoprotein. Use of the recombinant attenuated MOPV to induce an immune response in a subject.
    Type: Application
    Filed: November 30, 2020
    Publication date: July 8, 2021
    Inventors: Sylvain BAIZE, Audrey PAGE, Xavier CARNEC, Mathieu Jean Simon MATEO, Stephanie REYNARD, Alexandra FIZET
  • Publication number: 20210121917
    Abstract: A powder sieving system that is configured as part of a powder reclamation system is provided. The powder sieving system includes a support structure; and a filter housing movable relative to the support structure, the filter housing defining an inlet and an outlet and comprising a broad frequency filter disposed between the inlet and the outlet, the broad frequency filter including: a first filter fixed relative to the filter housing, the first filter being substantially rigid; and a second filter coupled within the filter housing adjacent to the first filter, the second filter being substantially flexible such that the second filter is movable relative to the first filter within the filter housing when the filter housing moves relative to the support structure, the first filter and the second filter configured to restrict a first portion of a powder larger than a predetermined threshold from reaching the outlet.
    Type: Application
    Filed: October 29, 2019
    Publication date: April 29, 2021
    Inventors: Anthony Charlebois, Mathieu Roy, Patrick Gauthier, Matthieu Balmayer, Abdelilah Ahssinou, Jean-Simon Meunier-Garnier
  • Publication number: 20210116142
    Abstract: Computing device and method using a neural network to adjust temperature measurements. The computing device comprises a temperature sensing module, one or more processor and a display. The neural network receives as inputs a plurality of consecutive temperature measurements performed by the temperature sensing module, a plurality of consecutive utilization metrics of the one or more processor, and a plurality of consecutive utilization metrics of the display. The neural network outputs an inferred temperature, which is an adjustment of the temperature measured by the temperature sensing module to take into consideration heat dissipated by the one or more processor and the display when using the temperature sensing module for measuring the temperature in an area where the computing device is deployed. An example of computing device is a smart thermostat. A corresponding method for training a neural network to adjust temperature measurements is also disclosed.
    Type: Application
    Filed: October 22, 2019
    Publication date: April 22, 2021
    Inventors: Jean-Simon BOUCHER, Francois GERVAIS
  • Patent number: 10973274
    Abstract: A helmet is provided. The helmet includes a helmet shell and a mounting system laterally positioned on the helmet shell. The helmet further includes a visor removably and pivotally connected to the mounting system, the visor being movable between lowered and raised positions. Finally, the helmet includes a peak removably connected to the mounting system, the mounting system being operable to disengage the visor and the peak upon manual operation thereof. A mounting system for customizing a helmet is also provided. Finally, a method of configuring the helmet is provided.
    Type: Grant
    Filed: July 31, 2018
    Date of Patent: April 13, 2021
    Assignee: Kimpex Inc.
    Inventors: Jean-Simon Levesque, Nicolas Bouchard Fortin, Étienne Gilbert, Stéphane Dion