Patents by Inventor Jean Simon

Jean Simon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180303927
    Abstract: A recombinant attenuated Mopeia virus (MOPV) comprising a recombinant genomic S segment that encodes a nucleoprotein having attenuated exonuclease activity, and optionally further encodes a non-MOPV arenavirus glycoprotein. Use of the recombinant attenuated MOPV to induce an immune response in a subject.
    Type: Application
    Filed: October 24, 2016
    Publication date: October 25, 2018
    Inventors: Sylvain BAIZE, Audrey PAGE, Xavier CARNEC, Mathieu Jean Simon MATEO, Stephanie REYNARD, Alexandra FIZET
  • Publication number: 20180305345
    Abstract: Provided are compounds that enhance the efficacy of viruses by increasing spread of the virus in cells, increasing the titer of virus in cells, or increasing the cytotoxicity of virus to cells. Other uses, compositions and methods of using same are also provided.
    Type: Application
    Filed: January 26, 2016
    Publication date: October 25, 2018
    Applicants: Ottawa Hospital Research Institute, University of Ottawa
    Inventors: Jean-Simon Diallo, Christopher Noyce Boddy, Mark Dornan, Ramya Krishnan, Fabrice Le Boeuf, John C. Bell, Andrew Macklin, Jeffrey Smith
  • Publication number: 20180295926
    Abstract: A ventilated helmet is provided. The helmet includes a shell defining a cavity, the shell having a front section provided with an opening to allow the wearer to see. The helmet also includes a transparent shield adapted having an inner surface and being adapted to substantially close the opening. Finally, the helmet includes a ventilation system having an evacuation subsystem adapted to create an evacuation airflow to evacuate humid air within the cavity to a surrounding environment. The ventilation system further has a pressurizing subsystem adapted to admit a pressurizing airflow within the cavity to create a high-pressure zone and a low-pressure zone within the cavity, wherein when in use, the wearer exhales air within the low-pressure zone, and wherein the high-pressure zone prevents air within the cavity from travelling from the low-pressure zone to the high-pressure zone. A method of evacuating humid air from the cavity is also provided.
    Type: Application
    Filed: April 18, 2018
    Publication date: October 18, 2018
    Inventors: Nicolas BOUCHARD FORTIN, Robert HANDFIELD, Jean-Simon LÉVESQUE, Étienne GILBERT, Hachimi FELLOUAH, Marouen DGHIM
  • Patent number: 10066214
    Abstract: Described herein is a method of enhancing virus replication in permissive cells that express a receptor to FGF2 protein. The method includes administering FGF2 protein or a functional variant thereof and the virus to the permissive cells. An oncolytic virus having a genome that includes an open reading frame that encodes FGF2 protein or a functional variant thereof is also described.
    Type: Grant
    Filed: June 16, 2014
    Date of Patent: September 4, 2018
    Assignee: Turnstone Limited Partnership
    Inventors: Carolina Solange Ilkow, Fabrice Le Boeuf, John Cameron Bell, Jean-Simon Diallo, Rozanne Arulanandam
  • Publication number: 20180237753
    Abstract: Described herein is a method of enhancing virus replication in permissive cells that express a receptor to FGF2 protein. The method includes administering FGF2 protein or a functional variant thereof and the virus to the permissive cells. An oncolytic virus having a genome that includes an open reading frame that encodes FGF2 protein or a functional variant thereof is also described.
    Type: Application
    Filed: March 13, 2018
    Publication date: August 23, 2018
    Inventors: Carolina Solange ILKOW, Fabrice LE BOEUF, John Cameron BELL, Jean-Simon DIALLO, Rozanne ARULANANDAM
  • Publication number: 20180163540
    Abstract: Construction element for creating a tunnel, including an incompressible concrete first layer and a compressible second layer securedly united to the first layer to form a monoblock prefabricated construction element to be integrated in a section of the tunnel, the second layer including a material comprising granulates aggregated by a binder, and cavities sunk into the material.
    Type: Application
    Filed: April 4, 2016
    Publication date: June 14, 2018
    Applicants: AGENCE NATIONALE POUR LA GESTION DES DECHETS RADIOACTIFS, CONSTRUCTIONS MÉCANIQUES CONSULTANTS
    Inventor: Jean SIMON
  • Publication number: 20180112190
    Abstract: Provided are compounds that enhance the efficacy of viruses by increasing spread of the virus in cells, increasing the titer of virus in cells, or increasing the antigen expression from a virus, gene or trans-gene expression from a virus, or virus protein expression in cells. Other uses, compositions and methods of using same are also provided.
    Type: Application
    Filed: January 26, 2016
    Publication date: April 26, 2018
    Applicants: Ottawa Hospital Research Institute, University of Ottawa
    Inventors: Jean-Simon Diallo, Christopher Noyce Boddy, Mark Dornan, Ramya Krishnan, Rozanne Arulanandam, Fabrice Le Boeuf, Jeffrey Smith, Andrew Macklin
  • Publication number: 20180064805
    Abstract: A vaccination method is provided. The method comprises administering to a mammal a histone deacytelase inhibitor in conjunction with a vaccine that expresses an antigen to which the mammal has a pre-existing immunity.
    Type: Application
    Filed: October 16, 2017
    Publication date: March 8, 2018
    Inventors: Byram Bridle, Brian Lichty, Yonghong Wan, Jean-Simon Diallo, Chantal Lemay, John Bell
  • Patent number: 9821054
    Abstract: A vaccination method is provided. The method comprises administering to a mammal a histone deacytelase inhibitor in conjunction with a vaccine that expresses an antigen to which the mammal has a pre-existing immunity.
    Type: Grant
    Filed: March 9, 2012
    Date of Patent: November 21, 2017
    Assignee: Turnstone Limited Partnership
    Inventors: Byram Bridle, Brian Lichty, Yonghong Wan, Jean-Simon Diallo, Chantal Lemay, John Bell
  • Patent number: 9727804
    Abstract: Determining a set of edit operations to perform on a string, such as one generated by optical character recognition, to satisfy a string template by determining a minimum cost of performing edit operations on the string to satisfy the string template and then determining the set of edit operations corresponding to the minimum cost. Transforming a string to satisfy one or more string templates by determining a minimum cost of performing edit operations on the string to satisfy one or more string templates, selecting one or more minimum costs, determining a set of edit operations corresponding to the minimum costs, and then performing the set of edit operations on the string. Determining a minimum cost of performing edit operations on a string to satisfy a string template by determining set costs of performing sets of edit operations using costs associated with edit operations of the set and determining the minimum cost using the set costs.
    Type: Grant
    Filed: April 15, 2005
    Date of Patent: August 8, 2017
    Assignee: Matrox Electronic Systems, LTD.
    Inventor: Jean-Simon Lapointe
  • Patent number: 9692387
    Abstract: A balun includes a dielectric layer having first and second sides, an electrically conductive plate on the second side of the dielectric layer, a first electrically conductive line on the first side and comprising a first end electrically connected to a first terminal and a second end, a second electrically conductive line on the second side and comprising a third end electrically coupled to a second terminal and a fourth end connected to an unbalanced terminal and a micro strip line comprising a fifth end electrically connected to the third end and a sixth end. The first electrically conductive line overlaps the second electrically conductive line. The second and the sixth ends are electrically coupled to the electrically conductive plate. The electrically conductive plate is hollowed in at least a region corresponding to an overlap area of the first electrically conductive line and second electrically conductive line.
    Type: Grant
    Filed: December 28, 2015
    Date of Patent: June 27, 2017
    Assignee: NXP USA, INC.
    Inventors: Jeremie Jean Simon, Laurent Gauthier, Maria Del Carmen Medina Urturi, Lionel Mongin
  • Publication number: 20170167261
    Abstract: Construction element for creating a tunnel, including a first incompressible layer of concrete and a second compressible layer securely fastened to the first layer to form a monoblock prefabricated construction element configured to be integrated in a section of the tunnel during creation of the tunnel, the second layer including a plurality of devices each having a solid body integrating an empty space.
    Type: Application
    Filed: May 20, 2015
    Publication date: June 15, 2017
    Applicant: CONSTRUCTIONS MÉCANIQUES CONSULTANTS
    Inventor: Jean SIMON
  • Publication number: 20170026023
    Abstract: A balun includes a dielectric layer having first and second sides, an electrically conductive plate on the second side of the dielectric layer, a first electrically conductive line on the first side and comprising a first end electrically connected to a first terminal and a second end, a second electrically conductive line on the second side and comprising a third end electrically coupled to a second terminal and a fourth end connected to an unbalanced terminal and a micro strip line comprising a fifth end electrically connected to the third end and a sixth end. The first electrically conductive line overlaps the second electrically conductive line. The second and the sixth ends are electrically coupled to the electrically conductive plate. The electrically conductive plate is hollowed in at least a region corresponding to an overlap area of the first electrically conductive line and second electrically conductive line.
    Type: Application
    Filed: December 28, 2015
    Publication date: January 26, 2017
    Inventors: Jeremie Jean Simon, Laurent Gauthier, Maria Del Carmen Medina Urturi, Lionel Mongin
  • Patent number: 9447016
    Abstract: A method is disclosed for the preparation of glycerol esters (triglycerides) of medium-chain length monocarboxylic fatty acids which consists of the reaction of the precursor free fatty acid and glycerol in the presence of a catalyst under partial vacuum. The process preferably uses a metal catalyst such as an oxide or a chloride of tungsten, molybdenum, calcium, zinc, chromium or magnesium. The method of the invention allows the preparation in high yield and high purity (>99.5%) of the final triglyceride. The present method allows the formation of triglycerides without solvent. Are also contemplated, the triglyceride obtained by the method, and the pharmaceutical composition containing the triglyceride as an excipient or as an active ingredient.
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: September 20, 2016
    Assignee: Prometic Pharma SMT Limited
    Inventors: Zacharie Boulos, Jean-Simon Duceppe, Christopher Penney
  • Publication number: 20160152304
    Abstract: A tunnel guard for a tunnel of a snowmobile has first and second arms. Each arm has a first end portion and a second end portion. The first end portions of the first and second arms have first and second connection elements respectively for connecting the first end portions of the arms to an interior of the tunnel. At least one member extends from at least one of the arms and is connected to the at least one of the arms. The at least one member has a third connection element for connecting the at least one member to the interior of the tunnel. The third connection element is disposed at a position that is one of: laterally between the first and second arms, and laterally outward of the first and second arms. A snowmobile having a tunnel guard and a method for connecting a tunnel guard are also disclosed.
    Type: Application
    Filed: November 27, 2015
    Publication date: June 2, 2016
    Inventors: Sebastien VEZINA, Jean-Simon LAVALLEE
  • Publication number: 20160130563
    Abstract: Described herein is a method of enhancing virus replication in permissive cells that express a receptor to FGF2 protein. The method includes administering FGF2 protein or a functional variant thereof and the virus to the permissive cells. An oncolytic virus having a genome that includes an open reading frame that encodes FGF2 protein or a functional variant thereof is also described.
    Type: Application
    Filed: June 16, 2014
    Publication date: May 12, 2016
    Inventors: Carolina Solange ILKOW, Fabrice LE BOEUF, John Cameron BELL, Jean-Simon DIALLO, Rozanne ARULANANDAM
  • Patent number: 9283254
    Abstract: Provided are viral sensitizing compounds that enhance the efficacy of viruses by increasing spread of the virus in cells, increasing the titer of virus in cells, or increasing the cytotoxicity of virus to cells. Other uses, compositions and methods of using same are also provided.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: March 15, 2016
    Assignee: Ottawa Hospital Research Institute
    Inventors: John Bell, Jean-Simon Diallo, Fabrice Le Boeuf
  • Publication number: 20160026771
    Abstract: A system and method for scoring and comparing communities includes the development of community health measures by on combining and supplementing healthcare data and community data from numerous sources. The community health measures may be stored in a community health measures database and may be accessed by interactive tools to generate customized representations of healthcare measures for selected communities. The representations are automatically computed in response to interactive user selections. Geographic map representation, heat map representations and data tables may be automatically generated to identify correlations between health outcomes and population attributes in different communities.
    Type: Application
    Filed: December 10, 2014
    Publication date: January 28, 2016
    Inventors: Carol Jean Simon, Paul A Bleicher, John Edward Hargraves, Paul John Wallace
  • Publication number: 20160026942
    Abstract: A system and method for identifying relationships and correlations between community healthcare attributes includes automatically displays relationships between selected community health measures. A correlation tool automatically computes correlations between a selected main measure and each other measures in a set of community health measures for selected communities. The correlation tool automatically displays a ranked list of the other community health measures based on their correlation to the selected main measure. A relationship tool automatically computes correlations between selected measures in the set of community health measures for selected communities. The relationship tool displays a correlation graph indicating values of the selected measures for each of a selected set of communities. An adjusted correlation graph is automatically displayed to indicate adjusted values of the selected measures to accommodate a selected third measure as a control variable.
    Type: Application
    Filed: March 18, 2015
    Publication date: January 28, 2016
    Applicant: Optum, Inc.
    Inventors: Carol Jean Simon, Paul A. Bleicher, John Edward Hargraves, Paul John Wallace
  • Patent number: 9180763
    Abstract: A cover for covering at least partially a vehicle comprises a cover body and at least two clips connected the cover body. Each of the at least two clips includes a first portion connected at least partially to the cover body. The first portion is adapted to bias the cover body toward the vehicle when the cover covers the vehicle. A second portion has a first end and a second end. The first end is connected to the first portion. The second portion is adapted to selectively connect to a first vehicle portion. A third portion has a first end and a second end. The third portion is adapted to selectively abut against a second vehicle portion. The first end of the third portion is connected to the second end of the second portion. The third portion is at an angle with respect to the first portion.
    Type: Grant
    Filed: June 30, 2014
    Date of Patent: November 10, 2015
    Assignee: BOMBARDIER RECREATIONAL PRODUCTS INC.
    Inventors: Eric Fournier, Jean-Simon Lavallee, Daniel Girard, Annie Leclerc