Patents by Inventor Jia-He Li

Jia-He Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS, METHODS AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING PARP
    Publication number: 20090088407
    Abstract: The present invention provides compounds which inhibit poly(ADP-ribose) polymerase (“PARP”), compositions containing these compounds and methods for using these PARP inhibitors to treat, prevent and/or ameliorate the effects of the conditions described herein.
    Type: Application
    Filed: October 20, 2008
    Publication date: April 2, 2009
    Applicant: MGI GP, Inc.
    Inventors: Vincent J. Kalish, Jie Zhang, Weizheng Xu, Jia-He Li, Amy Dongxia Xing, Qun Liu
  • Compounds, methods and pharmaceutical compositions for inhibiting PARP
    Patent number: 7456178
    Abstract: The present invention provides compounds which inhibit poly(ADP-ribose) polymerase (“PARP”), compositions containing these compounds and methods for using these PARP inhibitors to treat, prevent and/or ameliorate the effects of the conditions described herein.
    Type: Grant
    Filed: August 6, 2007
    Date of Patent: November 25, 2008
    Assignee: MGI GP, Inc.
    Inventors: Vincent Kalish, Jie Zhang, Weizheng Xu, Jia-He Li, Amy Dongxia Xing, Qun Liu
  • COMPOUNDS, METHODS AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING PARP
    Publication number: 20080058325
    Abstract: The present invention provides compounds which inhibit poly(ADP-ribose) polymerase (“PARP”) compositions containing these compounds and methods for using these PARP inhibitors to treat, prevent and/or ameliorate the effects of the conditions described herein.
    Type: Application
    Filed: August 6, 2007
    Publication date: March 6, 2008
    Applicant: MGI GP, INC.
    Inventors: Vincent Kalish, Jie Zhang, Weizheng Xu, Jia-He Li, Amy Xing, Qun Liu
  • Compounds, methods and pharmaceutical compositions for treating cellular damage, such as neural or cardiovascular tissue damage
    Patent number: 7307080
    Abstract: The disclosure relates to compounds, pharmaceutical compositions and methods for inhibiting PARP by use of the disclosed compositions.
    Type: Grant
    Filed: February 6, 2004
    Date of Patent: December 11, 2007
    Assignee: MGI GP, Inc.
    Inventors: Jia-He Li, Jie Zhang
  • Compounds, methods and pharmaceutical compositions for inhibiting PARP
    Patent number: 7268138
    Abstract: The present invention provides compounds which inhibit poly(ADP-ribose) polymerase (“PARP”), compositions containing these compounds and methods for using these PARP inhibitors to treat, prevent and/or ameliorate the effects of the conditions described herein.
    Type: Grant
    Filed: May 26, 2004
    Date of Patent: September 11, 2007
    Assignee: MGI GP, Inc.
    Inventors: Vincent J. Kalish, Jie Zhang, Weizheng Xu, Jia-He Li, Amy Dongxia Xing, Qun Liu
  • Compounds, derivatives, compositions, preparation and uses
    Patent number: 7247641
    Abstract: This invention relates to compounds, pharmaceutical compositions, and methods of using the disclosed compounds for inhibiting PARP.
    Type: Grant
    Filed: August 6, 2002
    Date of Patent: July 24, 2007
    Assignee: MGI GP, Inc.
    Inventors: Weizheng Xu, Dana V. Ferraris, Jia-He Li, Vincent J. Kalish
  • Compounds and their uses
    Patent number: 7235557
    Abstract: This invention relates to compounds, pharmaceutical compositions, and methods of using the disclosed compounds for inhibiting PARP.
    Type: Grant
    Filed: February 21, 2006
    Date of Patent: June 26, 2007
    Assignee: MGI GP, Inc.
    Inventors: Dana Victor Ferraris, Jia-He Li, Vincent Kalish, Jie Zhang
  • Substituted 4,9-dihydrocyclopenta{imn}phenanthridine-5-ones derivatives thereof and their uses
    Patent number: 7157452
    Abstract: This invention relates to compounds, pharmaceutical compositions, and methods of using the disclosed compounds for inhibiting PARP.
    Type: Grant
    Filed: December 24, 2002
    Date of Patent: January 2, 2007
    Assignee: MGI GP, Inc.
    Inventors: Jia-He Li, Jie Zhang, Vincent Kalish
  • Compounds and their uses
    Publication number: 20060142266
    Abstract: This invention relates to compounds, pharmaceutical compositions, and methods of using the disclosed compounds for inhibiting PARP.
    Type: Application
    Filed: February 21, 2006
    Publication date: June 29, 2006
    Applicant: MGI GP, Inc.
    Inventors: Dana Ferraris, Jia-He Li, Vincent Kalish, Jie Zhang
  • Heterocyclic ketone and thioester compounds and uses
    Patent number: 6984639
    Abstract: This invention relates to neurotrophic, low molecular weight, small molecule heterocyclic ketone and thioester compounds, compositions containing the same, and the use of such compounds for treating neurological disorders, including physically damaged nerves and neurodegenerative diseases.
    Type: Grant
    Filed: July 10, 2003
    Date of Patent: January 10, 2006
    Assignee: GPI NIL Holdings, Inc.
    Inventors: Gregory S. Hamilton, Jia-He Li
  • Compounds and their uses
    Publication number: 20060003987
    Abstract: This invention relates to compounds, pharmaceutical compositions, and methods of using the disclosed compounds for inhibiting PARP.
    Type: Application
    Filed: August 30, 2005
    Publication date: January 5, 2006
    Applicant: Guilford Pharmaceuticals, Inc.
    Inventors: Dana Ferraris, Jia-He Li, Vincent Kalish, Jie Zhang
  • Heterocyclic ketone and thioester compounds and uses
    Publication number: 20050148637
    Abstract: This invention relates to neurotrophic, low molecular weight, small molecule heterocyclic ketone and thioester compounds, compositions containing the same, and the use of such compounds for treating neurological disorders, including physically damaged nerves and neurodegenerative diseases.
    Type: Application
    Filed: March 3, 2005
    Publication date: July 7, 2005
    Inventors: Gregory Hamilton, Jia-He Li
  • Compounds and their uses
    Publication number: 20050148575
    Abstract: This invention relates to compounds, pharmaceutical compositions, and methods of using the disclosed compounds for inhibiting PARP.
    Type: Application
    Filed: February 28, 2005
    Publication date: July 7, 2005
    Applicant: Guilford Pharmaceuticals Inc.
    Inventors: Dana Ferraris, Jia-He Li, Vincent Kalish, Jie Zhang
  • Compounds and their use
    Patent number: 6887996
    Abstract: This invention relates to compounds, pharmaceutical compositions, and methods of using the disclosed compounds for inhibiting PARP.
    Type: Grant
    Filed: November 30, 2001
    Date of Patent: May 3, 2005
    Assignee: Guilford Pharmaceuticals Inc.
    Inventors: Dana V. Ferraris, Jia-He Li, Vincent J. Kalish, Jie Zhang
  • Compounds, methods and pharmaceutical compositions for treating cellular damage, such as neural or cardiovascular tissue damage
    Publication number: 20050074470
    Abstract: This invention relates to compounds, pharmaceutical compositions, and methods of using the disclosed compounds for inhibiting PARP.
    Type: Application
    Filed: February 6, 2004
    Publication date: April 7, 2005
    Applicant: Guilford Pharmaceuticals, Inc.
    Inventors: Jia-He Li, Jie Zhang
  • Compounds, methods and pharmaceutical compositions for inhibiting PARP
    Publication number: 20050020595
    Abstract: The present invention provides compounds which inhibit poly(ADP-ribose) polymerase (“PARP”), compositions containing these compounds and methods for using these PARP inhibitors to treat, prevent and/or ameliorate the effects of the conditions described herein.
    Type: Application
    Filed: May 26, 2004
    Publication date: January 27, 2005
    Inventors: Vincent Kalish, Jie Zhang, Weizheng Xu, Jia-He Li, Amy Xing, Qun Liu
  • Substituted 4,9-dihydrocyclopentaimnphenanthridine-5-ones derivatives thereof and their uses
    Publication number: 20040259900
    Abstract: This invention relates to compounds, pharmaceutical compositions, and methods of using the disclosed compounds for inhibiting PARP.
    Type: Application
    Filed: August 16, 2004
    Publication date: December 23, 2004
    Inventors: Jia-He Li, Jie Zhang, Vincent Kalish
  • Compounds, derivatives, compositions, preparation and uses
    Publication number: 20040254372
    Abstract: This invention relates to compounds, pharmaceutical compositions, and methods of using the disclosed compounds for inhibiting PARP.
    Type: Application
    Filed: February 9, 2004
    Publication date: December 16, 2004
    Inventors: Weizheng Xu, Dana V. Ferraris, Jia-He Li, Vincent J. Kalish
  • Heterocyclic ketone and thioester compounds and uses
    Publication number: 20040106652
    Abstract: This invention relates to neurotrophic, low molecular weight, small molecule heterocyclic ketone and thioester compounds, compositions containing the same, and the use of such compounds for treating neurological disorders, including physically damaged nerves and neurodegenerative diseases.
    Type: Application
    Filed: July 10, 2003
    Publication date: June 3, 2004
    Applicant: GPI NIL Holdings, Inc.
    Inventors: Gregory S. Hamilton, Jia-He Li
  • Sulfonamide and carbamide derivatives of 6(5H)phenanthridinones and their uses
    Patent number: 6723733
    Abstract: This invention relates to compounds, pharmaceutical compositions, and methods of using the disclosed compounds for inhibiting PARP.
    Type: Grant
    Filed: May 15, 2001
    Date of Patent: April 20, 2004
    Assignee: Guilford Pharmaceuticals, Inc.
    Inventors: Jia-He Li, Vincent J. Kalish, Jie Zhang, Larisa E. Serdyuk, Dana Victor Ferraris, Ge Xiao, Paul W. Kletzly