Abstract: Systems and methods for configuring hardware resources of an electronic device based on operating characteristics of the electronic device are provided. In one embodiment, a processor may configure the hardware resources of the electronic device that equally weighs decisions made by a machine learning (ML) engine and a finite state machine (FSM) engine. In another embodiment, the processor may configure the hardware resources of the electronic device that gives greater weight to decisions made by the ML engine compared to decisions made by the FSM engine. In yet another embodiment, the processor may configure the hardware resources of the electronic device that gives greater weight to decisions made by the FSM engine compared to decisions made by the ML engine.

Abstract: The present invention relates to methods of making certain pyrrolopyrimidine derivatives, which are useful in the treatment of proliferation disorders and other diseases related to the dysregulation of kinase (such as, but not limited to, EGFR (including HER), Alk, PDGFR, BLK, BMX/ETK, BTK, FLT3(D835Y), ITK, JAK1, JAK2, JAK3, TEC and TXK) and/or the respective pathways, salts, polymorphs, and amorphous forms of said compounds, synthetic intermediates for preparing said compounds, and pharmaceutical compositions comprising said compounds and methods for making such compositions.

Abstract: Provided are amino acid sequences capable of binding to and inhibiting a Cas protein's ability to bind to a nucleic acid molecule, thereby inhibiting the Cas protein's function in genome editing. Such Cas protein inhibitors, which can be comprised of a major coat protein (G8P), an extracellular region of the G8P (G8PEX), or a biological equivalent, are useful in improving the specificity of Cas protein-based genome editing procedures.

Abstract: A disk device according to one embodiment includes a first conversion device, a second conversion device, an optical waveguide, a first component, and a second component. The first conversion device emits light corresponding to an electric signal. The second conversion device generates an electric signal corresponding to incident light. The optical waveguide includes a first end joined to the first conversion device and a second end joined to the second conversion device, and transmits light emitted from the first conversion device to the second conversion device. The first component is electrically connected to the first conversion device. The second component is electrically connected to the second conversion device, and communicates with the first component through the first conversion device, the optical waveguide, and the second conversion device.

Abstract: According to one embodiment, a disk device includes a housing having a first transmission hole, a magnetic disk, a head, a first sealing material having an inner surface and an outer surface and closing the first transmission hole, and a first wireless power feeding device having a first power feeding antenna. The first power feeding antenna is located mere inward of the housing than the outer surface of the first sealing material, and receives power transmitted through the first sealing material by wireless power feeding.

Abstract: The present disclosure relates to a storage box. The storage box includes a body, a cover, and a first magnetic unit. The body is provided with a receiving space. The cover is rotatably attached to the body and is configured to rotate relative to the body to drive the storage box between an open state and a closed state. In the open state, the cover covers the receiving space. In the closed state, the receiving space is exposed. The first magnetic unit includes a first magnetic member attached to the body and a first attracting member attached to the cover. Opening the storage box from the closed state causes the first attracting member to move closer to the first magnetic member. Magnetic force between the first magnetic member and the first attracting member drives the cover to rotate away from the closed state and into the open state.

Abstract: A disk device includes a housing having a sidewall, the side wall having a first through-hole; a magnetic disk rotatably disposed in the housing and surrounded by the sidewall in a radial direction; a flexible printed circuit electrically connected to the magnetic disk; an insulator closing the first through-hole; a wireless communication device having a first communication antenna inside the housing; and a control board electrically connected to the flexible printed circuit. The control board is supplied with power from outside of the housing via a first connector, and is configured to receive a write command or a read command via the first communication antenna.

Abstract: The invention provides a recombinant Escherichia coli strain for producing succinic acid and a construction method thereof. The by-product encoding genes in the E. coli strain FMME-N-2 are knocked out to obtain the E. coli strain FMME-N-5 (?focA-pflB-?ldhA-?pta-ackA); and the phosphoenolpyruvate carboxykinase pck derived from Actinobacillus succinogenes and the phosphite dehydrogenase ptxD derived from Pseudomonas stutzeri were overexpressed. The constructed plasmid pTrcHisA-pck-ptxD was introduced into the expression host E. coli FMME-N-5 (?focA-pflB-?ldhA-?pta-ackA), and the cells were screened in a plate containing ampicillin, to obtain an engineered strain E. coli FMME-N-5 (?focA-pflB-?ldhA-?pta-ackA)-pck-ptxD that can efficiently produce succinic acid. After fermentation by a two-stage fermentation strategy, the production of succinic acid reaches 137 g/L, the yield of succinic acid is up to 1 g/g glucose, and the space time yield is 1.

Abstract: When a chatbot application is in a mode of live chat conversation with a user, a trained intent classifier determines an intent that underlies a first live question received by the trained intent classifier from the user. A trained next predictor receives the intent from the intent classifier. The trained next intent predictor generates a set of predicted next intents responsive to receiving the intent. A trained re-ranker selects at least one of the predicted next intents responsive to receiving the set of predicted next intents. A question selection engine sends at least one suggested question to the user responsive to receiving the at least one predicted next intent. As a result of the above, the chatbot application provides to the user at least one suggested next question the user may wish to ask in response to the first question from the user.

Abstract: Systems and methods are described implementing streaming analytics on a serverless compute system. A user can specify a data stream against which analytics should be conducted, serverless functions to be used to conduct the analysis, and criteria for the analytics, such as windowing criteria and aggregation criteria. The windowing criteria can specify windows of items within the stream that should be collectively analyzed. The aggregation criteria can specify how to group items within each window during analysis. A poller device can read data items from the stream, window and group the items according to the windowing and aggregation criteria, and invoke serverless functions to conduct streaming analytics on the data items. The poller device can further maintain state between invocations.

Abstract: The present invention generally relates to nanoscale wires and nanoelectronics, which in some aspects may be embedded in biological structures, such as tissues, organoids, organs, organisms, and the like. For example, one aspect is generally directed to stretchable cell scaffolds, which may be connected to electrical circuits. In some cases, a biological structure may form around the scaffold and deform the cell scaffold as it forms, thereby causing the cell scaffold to become embedded within the biological structure. The scaffold may be connectable in certain embodiments to an external device, e.g., to determine a property of the cell scaffold (e.g., an electrical property), and/or to apply a stimulus (e.g., an electrical stimulus) to the biological structure. Other aspects of the invention are generally directed to methods of making or using such cell scaffolds, kits including such cell scaffolds, biological structures containing such cell scaffolds, or the like.

Abstract: Disclosed is a mutant of acid phosphatase and an application thereof, belonging to the technical field of biological engineering. The disclosure provides a mutant of acid phosphatase PaAPaseMu3. By expressing the mutant of acid phosphatase PaAPaseMu3 in Escherichia coli and using a whole-cell conversion method, L-ascorbic acid is transformed into L-ascorbate-2-phosphate. Moreover, a catalytic system of the mutant of acid phosphatase PaAPaseMu3 is optimized from the aspects of reaction pH and temperature, so that a yield of L-ascorbate-2-phosphate can reach 90.1 g/L and a molar yield can reach 75.1%. Therefore, the problems of a high substrate cost, environmental pollution and the like before are greatly reduced, laying a foundation for the industrial green production of L-ascorbate-2-phosphate.

Abstract: A fully automatic online aero aluminum sorting and recovery system based on LIBS (Laser Induced Breakdown Spectroscopy) technology, which belongs to the field of aero aluminum sorting and recovery technology, and is suitable for online sorting, detection and recovery of large batch of aero aluminum. The fully automatic online aero aluminum sorting system based on LIBS technology provided in the present invention consists of six portions: a sample feeding unit (1), a surface treatment unit (2), a material positioning unit (3), a LIBS analysis and detection unit (4), a transfer unit (5) and a sorting and recovery unit (6). The system according to the invention can be used to realize the automatic online detection, sorting and recovery of aero aluminum, and the system does not have requirements on the surface condition of the recovered aero aluminum samples. The sorting accuracy rate is greater than 90% and the sorting rate is not less than 1 block per second.

Abstract: A method for voice recognition via an earphone is disclosed. The method includes receiving first audio data via the first microphone and buffering the first audio data in response to the first trigger signal; receiving second audio data via the first microphone and recognizing whether the first audio data contains data of a wake-on-voice word in response to the second trigger signal; and recognizing whether the second audio data contains data of the wake-on-voice word. The first audio data is received and buffered in a first duration starting from when the first trigger signal is received and ending when the second trigger signal is received. The second audio data is received in a second duration starting from when the second trigger signal is received and ending when whether the first audio data contains data of the wake-on-voice word is recognized.

Abstract: Embodiments of this application provide a synchronization signal/physical broadcast channel block (SSB) measurement method and an apparatus. One example method includes that a terminal device receives first information and second information. The first information indicates a time domain position of an SSB sent by a serving cell, and the second information indicates a set of SSBs that the terminal device needs to measure and that are sent by a neighboring cell. The terminal device measures, in a first measurement window based on the first information, the SSB sent by the serving cell. The terminal device measures, in a second measurement window based on the second information, the SSB sent by the neighboring cell.

Abstract: According to one embodiment, a disk device includes a housing including a sidewall, a magnetic disk, a wireless communication device including a first communication antenna, and a first insulating member. The sidewall includes a first through portion. The first insulating member closes the first through portion. The first communication antenna is located in the first through portion, is disposed spaced from the housing, and wirelessly communicates with an outside of the housing.

Abstract: An electronic device includes a housing, a display assembly, a drive component, a support member, and a protection member. The housing includes an accommodation chamber and an opening. The opening is connected with the accommodation chamber. The accommodation chamber includes a first space and a second space. The first space overlaps with the opening along a first direction. The second space and the opening are staggered along the first direction. The display assembly is located in the first space of the accommodation chamber and exposed through the opening. The drive component is partially located in the second space of the accommodation chamber, electrically connected to the display assembly, and configured to drive the display assembly. The support member is fixed in the accommodation chamber. The protection member at the opening is fixedly connected to the display assembly, and connected to a portion of the support member.

Abstract: The present disclosure relates generally to roofing elements and methods for making them. In one embodiment, the disclosure provides a roofing element in the form of a roofing shingle that includes a body of a foamed cured cross-linked polymer, the body having a top surface and a bottom surface, the body extending substantially in a plane and having a thickness in the range of 0.5 mm to 35 mm; and a layer of weather-resistant roofing granules disposed on and adhered at the top surface of roofing element. The roofing element can be made by providing a body of wet foamed curable composition, and allowing the curable composition to cure to provide the body of foamed cured cross-linked polymer.

Abstract: Embodiments of this application disclose a switching method and a related apparatus. When a terminal device has a switching requirement, to sift a target network device for the terminal device, a source network device receives N pieces of data channel quality information, where the N pieces of data channel quality information are in a one-to-one correspondence with N candidate network devices, and each of the N pieces of data channel quality information is used to indicate coverage quality of a data channel between the terminal device and a candidate network device corresponding to the data channel quality information.

Abstract: The present disclosure belongs to the field of biotechnology, and particularly relates to a zinc finger protein-superoxide dismutase fusion protein with a cell membrane penetrating property, and a preparation and an application thereof. A domain of the fusion protein described in the present disclosure comprises a zinc finger protein and superoxide dismutase, and the fusion protein can enter cells to exert an antioxidant activity.