Abstract: A polypeptide or protein directional modification method based on sulfhydryl-alkenyl azide coupling is provided. The method uses a sulfhydryl group-containing compound and a compound containing alkenyl azide group as reactants to generate an amino acid containing ?-carbonyl sulfide, a polypeptide containing ?-carbonyl sulfide and a protein bioconjugate containing ?-carbonyl sulfide, thereby achieving a chemical modification. The method is mild in conditions and wide in solvent selectivity, a reaction temperature is in a range of 37 degrees Celsius (° C.) to 40° C., and a reaction time is in a range of 10 minutes to 48 hours. The method is promising in preparing functional polypeptides or functional proteins, protein labeling, and biological medicine.

Abstract: Still frame detection for single pass video data, including: determining that an average quantization parameter of a frame of video data falls below a quantization parameter threshold; determining whether an amount of skipped macroblocks in the frame meets a skipped macroblock threshold; and responsive to the amount of skipped macroblocks exceeding the skipped macroblock threshold, identifying the frame as a still frame.

Abstract: An integrated circuit includes a TSV extending from a first surface of a semiconductor substrate to a second surface of the semiconductor substrate and having a first end and a second end, and a non-volatile repair circuit. The non-volatile repair circuit includes a one-time programmable (OTP) element having a programming terminal, wherein in response to an application of a fuse voltage to the programming terminal, the OTP element electrically couples the first end of the TSV to the second end of the TSV.

Abstract: An integrated circuit includes a TSV extending from a first surface of a semiconductor substrate to a second surface of the semiconductor substrate and having a first end and a second end, and a non-volatile repair circuit. The non-volatile repair circuit includes a one-time programmable (OTP) element having a programming terminal, wherein in response to an application of a fuse voltage to the programming terminal, the OTP element electrically couples the first end of the TSV to the second end of the TSV.

Abstract: A method for controlling includes activating a virtual subscriber identity module (SIM) card in a terminal such as a mobile phone in response to determining that the terminal is in a lost state; receiving a control instruction through the virtual SIM card; and controlling the terminal based on the control instruction. A mobile phone or an electronic device incorporating the method and a non-transitory computer readable storage medium are also described.

Abstract: Disclosed are a system-on-chip integrated packaging structure, a manufacturing method therefor and a three-dimensional stacked device. The system-on-chip integrated packaging structure includes: a substrate, a chip, a first electrical connection structure and a second electrical connection structure. A front surface of the substrate is provided with a recess and a via welding pad, and a back surface of the substrate is provided with a conductive via extending to the via welding pad. The chip is embedded in the recess, and a chip welding pad is disposed on a surface of the chip away from a bottom surface of the recess. Different chips may be electrically connected by means of the first electrical connection structure and the second electrical connection structure, which is conducive to form a three-dimensional stacked structure with high-density interconnection, miniaturized packaging and thinning.

Abstract: A technique for determining an adaptive quantization parameter offset for a block of encoded video includes obtaining a rate control factor for the quantization parameter, determining a content-based quantization parameter factor for the quantization parameter, determining an adaptive variance based quantization offset based on content-based quantization parameter factors for a frame prior to the current frame, and combining the rate control factor, the content-based quantization parameter factor, and the adaptive offset to generate the quantization parameter.

Abstract: Polynucleotide constructs and multifunctional engineered natural killer (NK) cells expressing such constructs are provided for the treatment of cancer and, in particular, glioblastoma. The constructs are a fusion of a first binding domain that targets at least one cognate ligand on a target cell, a second binding domain specific for an adenosine producing cell surface protein of the target cell or an adenosine-intermediary producing cell surface protein of the target cell and a cleavable linker, and a third binding domain specific for a cancer-associated antigen. Pharmaceutical compositions of the engineered NK cells are also provided, as well as methods of treating glioblastoma using such pharmaceutical compositions alone and in addition to autophagy inhibitors.

Abstract: The present disclosure relates to the field of tablet computer accessories, and in particular, to a protective case with an electronic function. The protective case with an electronic function according to the present disclosure provides a tablet with more extension functions, which can not only protect a tablet computer but also add functions to the tablet computer. Moreover, the protective case is further electrically connected to a corresponding external keyboard by magnetic adsorption, which is convenient to use and changes the tablet into a portable mini-laptop, which is especially suitable for mobile officing.

Abstract: Still frame detection for single pass video data, including: determining that an average quantization parameter of a frame of video data falls below a quantization parameter threshold; determining whether an amount of skipped macroblocks in the frame meets a skipped macroblock threshold; and responsive to the amount of skipped macroblocks exceeding the skipped macroblock threshold, identifying the frame as a still frame.

Abstract: Systems, apparatuses, and methods for generating a model for determining a quantization strength to use when encoding video frames are disclosed. A pre-encoder performs multiple encoding passes using different quantization strengths on a portion or the entirety of one or more pre-processed video frames. The pre-encoder captures the bit-size of the encoded output for each of the multiple encoding passes. Then, based on the multiple encoding passes, the pre-encoder generates a model for mapping bit-size to quantization strength for encoding video frames or portion(s) thereof. When the encoder begins the final encoding pass for one or more given video frames or any portion(s) thereof, the encoder uses the model to map a preferred bit-size to a given quantization strength. The encoder uses the given quantization strength when encoding the given video frame(s) or frame portion(s) to meet a specified bit-rate for the encoded bitstream.

Abstract: An ultrasound scanning control method applied to an ultrasound scanning device is provided. The ultrasound scanning device includes an execution mechanism. The execution mechanism includes a mechanical arm and a probe. The ultrasound scanning control method includes: controlling the mechanical arm to drive the probe to move according to a set scanning trajectory; and controlling the probe to collect an ultrasound image. A target region is identified from the collected ultrasound image. The scanning trajectory is adjusted when a position of the target region in the ultrasound image is not a predetermined position, and the mechanical arm is controlled to drive the probe to move according to the adjusted scanning trajectory.

Abstract: The disclosure relates to a medical moisturizing eye patch with excellent biocompatibility and lasting moisture retention and a preparation method thereof, in which firstly, the standing cultured bacterial cellulose film is purified and bleached; then, the bleached bacterial cellulose wet film is composited with a moisturizing agent; then, a mechanical pressing is made to be with a proper liquid content; and finally, a cutting is made to obtain the eye patch with a proper size, which has excellent biocompatibility, high water holding capacity, high purity, high wet strength and excellent flexibility, excellent water absorption and water locking effect, improved skin moisture content, good air permeability, antibacterial function and no side-effect. The preparation method in the disclosure is simple and easy to realize; and the eye patch can be directly applied after peeling away the backing layer in use.

Abstract: A device and method for a switch to operate as an intermediate node in a Time Sensitive Network (TSN) are provided. The switch transmits a frame at a time if it is the right frame to be transmitted at the time according to a configuration stored by the switch. The switch does not transmit the frame at the time if it is not the right frame to be sent at the time according to the configuration. Further, a device and method for scheduling transmission of a data packet from a talker node to a listener node are provided, including sending a configuration to each switch of a subset of switches in the network comprising information on the flow and a timing when it is to be output from the switch.

Abstract: This application discloses a temperature feedback control apparatus, method. The method includes two electric switches, a feedback control unit and an optical component. A first electric switch is configured to control that only a first channel of at least two channels that correspond to the first electric switch is conducted at a moment, to feed back an optical signal of a target optical component connected to the first channel to the feedback control unit. The feedback control unit is configured to calculate temperature of the corresponding optical component based on an electrical signal converted from the optical signal, to obtain a control signal. The second electric switch is configured to control, when the first channel is conducted, that only the second channel is conducted, to transmit the control signal to the target optical component to adjust its temperature. The optical component connects to both the first and second channels.

Abstract: A side sliding door of a railway vehicle comprises a door body (100), and a driving device for the opening and closing of a doorway. An outer surface of the door body (100) is flush with an outer surface of the vehicle body when the door body (100) is closed. A movement track of the door body is arranged as an arc-plus-linear reciprocating motion. The outer surface of the door body is flush with the outer surface of the vehicle body when the door body is closed, so that there exists no height difference between the vehicle body and a doorway of the side sliding door. Snow accumulation at doorway under an extreme cold working condition is avoided, and then the risk of a door body being frozen is reduced.

Abstract: A portable wire cutting device for sampling a steel ingot includes a wire rack device, a driving system, and a multi-axis moving device. The wire rack device includes a first corner wheel, a second corner wheel, a transition wheel, a steering wheel, a first wire rack, a second wire rack, and a wire winding drum. The driving system includes a wire drum motor and a molybdenum wire, wherein the wire drum motor provides power driving for the operation of a cutting line; and the molybdenum wire is a closed molybdenum wire coil connected in an end-to-end manner, the molybdenum wire is wrapped around the first corner wheel, the second corner wheel, the wire winding drum, and an inner side of the transition wheel in a looping manner, and during operation, the cutting line performs wire cutting on an object by the molybdenum wire.

Abstract: A portable wire cutting device for sampling a steel ingot includes a wire rack device, a driving system, and a multi-axis moving device. The wire rack device includes a first corner wheel, a second corner wheel, a transition wheel, a steering wheel, a first wire rack, a second wire rack, and a wire winding drum. The driving system includes a wire drum motor and a molybdenum wire, wherein the wire drum motor provides power driving for the operation of a cutting line; and the molybdenum wire is a closed molybdenum wire coil connected in an end-to-end manner, the molybdenum wire is wrapped around the first corner wheel, the second corner wheel, the wire winding drum, and an inner side of the transition wheel in a looping manner, and during operation, the cutting line performs wire cutting on an object by the molybdenum wire.

Abstract: A technique for determining an adaptive quantization parameter offset for a block of encoded video includes obtaining a rate control factor for the quantization parameter, determining a content-based quantization parameter factor for the quantization parameter, determining an adaptive variance based quantization offset based on content-based quantization parameter factors for a frame prior to the current frame, and combining the rate control factor, the content-based quantization parameter factor, and the adaptive offset to generate the quantization parameter.