Abstract: Provided are peptide biomarkers for diagnosis of allergy, monitoring development of clinical tolerance in an allergic individual, and predicting whether an allergic subject is likely to develop clinical or natural tolerance over time. The invention also relates to diagnostic methods and diagnostic kits employing the peptide biomarkers.

Abstract: Provided herein are methods of treating central nervous system (CNS) disorders (e.g., Binge Eating Disorder (BED), Attention-Deficit/Hyperactivity Disorder (ADHD), etc.) with a dasotraline therapy while avoiding adverse drug interactions.

Abstract: A pharmaceutical dosage form comprises a capsule shell and a fill composition, wherein the fill composition comprises an emulsion of (a) simethicone, (b) loperamide or a pharmaceutically acceptable salt thereof, and (c) at least two surfactants, wherein the emulsion has a hydrophilic lipophilic balance ranging from about 8 to about 12. Also described are methods of making the pharmaceutical dosage forms and methods for treating humans suffering from gastrointestinal distress.

Abstract: Certain aspects of the present disclosure relate to beam selection. An example method generally includes selecting, from a plurality of beams, a beam for uplink transmission during a particular time interval, the selecting being based on a transmission power and a radio frequency (RF) exposure for each of the plurality of beams and transmitting at least one uplink signal using the selected beam during the particular time interval.

Abstract: The disclosure provides a storage medium, an expansion base and an operation method thereof combined with a portable electronic device. The portable electronic device is pre-installed with an application program and includes a touch screen. The expansion base is paired with the portable electronic device and accommodates the portable electronic device. When the portable electronic device is accommodated inside the expansion base, a touch window on the surface of the expansion base exposes at least a portion of the touch screen, and the portable electronic device executes the application program to automatically adjust a size or a display position of a display image of the touch screen to correspond to the touch window.

Abstract: A system for developing a simulation of a process. In one aspect, a system creates a first model within the simulation. The first model represents a part of the process and comprises a first port to which other models may be connected. The system also creates a second model within the simulation. The second model represents another part of the process and comprises a second port to which other models may be connected. The system then connects the first port and the second port together. Upon connection, the system allocates a memory location as a connection variable that represents a type of information transfer between the first and second ports. A first port variable, which represents a value transferrable through the first port, is set to reference the value at the allocated memory location. Similarly, a second port variable, which represents a value transferrable through the second port, is also set to reference the value at the allocated memory location.

Abstract: A clock and data recovery circuit, a memory storage device and a signal adjustment method are disclosed. The method includes: detecting a phase difference between a first signal and a clock signal; generating a vote signal according to the phase difference and a first clock frequency; sequentially outputting a plurality of adjustment signals according to the vote signal and a second clock frequency, wherein the first clock frequency is different from the second clock frequency; and generating the clock signal according to the sequentially output adjustment signals.

Abstract: A clock and data recovery circuit, a memory storage device and a signal adjustment method are disclosed. The method includes: detecting a phase difference between a first signal and a clock signal; generating a vote signal according to the phase difference and a first clock frequency; sequentially outputting a plurality of adjustment signals according to the vote signal and a second clock frequency, wherein the first clock frequency is different from the second clock frequency; and generating the clock signal according to the sequentially output adjustment signals.

Abstract: The present invention relates to antisense oligonucleotides for modulating the activity of glycine decarboxylase (GLDC). In particular, the present invention relates to antisense oligonucleotides capable of inducing exon skipping of RNA. Also claimed are pharmaceutical compositions, kits and methods of treating cancer and inducing exon-skipping using said antisense oligonucleotides. In addition, a method for aiding the categorising or determining prognosis of a cancer or in selecting a therapeutic strategy for a patient with cancer, based on assessing the level of GLDC nucleic acid, protein or activity in a sample derived from the patient is provided.

Abstract: A virtual machine migration method and apparatus, that the method includes: downloading an image file of a to-be-migrated virtual machine from an object storage; starting a preset command to process the downloaded image file, to obtain a private image corresponding to the image file of the to-be-migrated virtual machine, and provisioning, by using the private image, a virtual machine that runs on a destination virtualization platform, where the preset command is configured based on a difference between a source virtualization platform and the destination virtualization platform. According to the foregoing method, the image file of the to-be-migrated virtual machine is processed by executing the preset command, so that automatic migration of the image file of the to-be-migrated virtual machine can be implemented, and a user does not need to perform a manual operation. This effectively improves migration efficiency and meets a user requirement.

Abstract: In a method for producing acetoin, butanediol, or butanol from ethanol according to the present invention, a cell-free catalysis method was used by designing an artificial synthetic pathway so that proteins of NOX, EtDH, FLS, BDH, and DDH and variant proteins thereof exhibit cascade catalytic activity as enzymes. Compared to existing fermentation methods using microorganisms, the production method according to the present invention does not require cell growth and has a short synthetic pathway, a fast reaction rate, high yield and productivity, adjustment of targeted reaction conditions is convenient, and butanol may be effectively produced. Moreover, same may be reused numerous times by fixing the proteins to nano-particles, and are also effective for producing acetoin, butanediol, or butanol, thus being economical. Therefore, the production method may be usefully adopted in the relevant industries requiring acetoin, butanediol, or butanol.

Abstract: A circuit check method and an electronic apparatus applicable to a to-be-tested circuit are provided. The to-be-tested circuit has one or more first nodes related to a gate voltage of one or more transistor devices and a plurality of second nodes. The circuit check method includes: setting endpoint voltages of a plurality of input interface ports of the to-be-tested circuit; obtaining a first node voltage of the first node according to a conduction path of the to-be-tested circuit and the gate voltage of the transistor device; obtaining a second node voltage of each second node according to the conduction path, the endpoint voltages, and the first node voltage; and performing circuit static check on the to-be-tested circuit by applying the first node voltage and the second node voltage.

Abstract: Embodiments of the present disclosure disclose an intelligent agent reinforcement learning method and apparatus, a device, and a medium. The method includes: acquiring key visual information on which an intelligent agent makes a policy for a current environment image; acquiring actual key visual information of the current environment image; determining attention variation reward information based on the key visual information and the actual key visual information; and adjusting reward feedback of reinforcement learning of the intelligent agent based on the attention variation reward information.

Abstract: A system for developing a simulation of a process. In one aspect, a system creates a first model within the simulation. The first model represents a part of the process and comprises a first port to which other models may be connected. The system also creates a second model within the simulation. The second model represents another part of the process and comprises a second port to which other models may be connected. The system then connects the first port and the second port together. Upon connection, the system allocates a memory location as a connection variable that represents a type of information transfer between the first and second ports. A first port variable, which represents a value transferrable through the first port, is set to reference the value at the allocated memory location. Similarly, a second port variable, which represents a value transferrable through the second port, is also set to reference the value at the allocated memory location.

Abstract: A signal receiving circuit, a memory storage device and a signal receiving method are provided. The signal receiving circuit includes an equalizer module, a clock and data recovery (CDR) circuit and a controller. The equalizer module is configured to receive a first signal and compensate the first signal to generate a second signal. The CDR circuit is configured to perform a phase locking on the second signal. The controller is configured to open or close a signal pattern filter of the CDR circuit according to the second signal, wherein the signal pattern filter is configured to filter a signal having a specific pattern in the second signal.

Abstract: Enteric softgel capsules comprise a fill material and an enteric shell composition, characterized in that the enteric nature of the capsules may be achieved without an enteric coating or added conventional enteric polymers.

Abstract: An electronic measurement apparatus includes a measurement device and a display device. The measurement device is configured to measure an object's weight and to generate a measurement signal. The display device is detachably assembled with the measurement device. Moreover, the display device can receive the measurement signal by wireless transmission, and the display device can display measurement data according to the measurement signal. Accordingly, the user can place the display device in an easy-to-view location to make it easier for the user to see the measurement data.