Abstract: A carburetor drain apparatus includes a carburetor bowl, a fuel supply pipe, a fuel drain pipe, and a bail interface. The carburetor bowl is configured to store fuel and provide the fuel to an air passage. The fuel supply pipe is connected a fuel tank and the carburetor bowl. The fuel drain pipe is connected to the carburetor bowl. The bail interface is configured to operate in response to actuation of a bail to open the fuel drain pipe.

Abstract: Systems and methods are disclosed for generation of secure indexes that permit the querying or searching of encrypted data in a cryptographically-secure manner. In various embodiments, a filter gradient comprises a node identifier, a set membership filter, and an ordered genealogy (such that it comprises a filter that encodes a subset of the items encoded by its parent), and a FiG tree is a rooted tree with filter gradients (and, optionally, one or more dictionaries) as nodes such that each filter gradient uses a different hash. A HiiT data structure, in various embodiments, comprises a hash table that points to the rows of an inverted index table. In various embodiments, an oblivious pseudorandom function may be employed to mask, secure, and prepare the phrases for insertion into the secure indexes.

Abstract: Systems, methods, and devices for network-based storage of vehicle and infrastructure data for vehicle optimization are disclosed. A method includes receiving sensor data from a vehicle sensor, uploading the sensor data to a network, and storing the sensor data in a vehicle map database. The method includes downloading aggregated drive data from the network and storing the aggregated drive data in the vehicle map database. The method includes optimizing a vehicle route based on route costs for a plurality of potential driving routes based on a reliability of an automated driving feature or driver assistance feature.

Abstract: Provided herein, inter alia, are compounds and methods of treating diseases including cancer, neurological disease, alcohol withdrawal, depression and anxiety, and neuropathic pain.

Abstract: An ultrasound system performs cranial therapy using a headset mounted to the head of a subject which contains a therapy transducer and a motion detecting transducer. At the outset of therapy, echo signals are acquired by the motion detecting transducer and stored. Thereafter, echo signals are acquired again by the motion detecting transducer and compared or correlated with the signals stored at the outset of therapy. When a difference is determined between the compared or correlated signals, an alert is issued by the system that transducer motion or acoustic decoupling may have occurred.

Abstract: A biodegradable triblock copolymer comprising: an A-B-A? structure wherein the A and A? blocks each include polylactide, the B block includes from about 55 to about 100 mole percent of polytrimethylene carbonate and 0 to about 45 mole percent polylactide, and the biodegradable triblock copolymer overall includes from about 15 to about 25 mole percent of the polytrimethylene carbonate and from about 75 to about 85 mole percent of the polylactide. Also provided are compositions and implantable medical devices made therefrom.

Abstract: A supercharger having twisted meshing rotors sealingly contained within a housing having an inlet port to admit air into the meshing rotors and an outlet port to expel air from the meshing rotors, the rotors having mesh points where the rotors contact one another and spaces between their mesh points to accept air from the inlet port and propel it to the outlet port as the rotors are rotated and the mesh points travel axially, the housing, inlet and rotors defining an angle known as the seal transfer angle which is greater than or equal to zero degrees when the inlet port is closed and the volume of air between rotors is sealed and has no leakage path. In the described supercharger the housing, rotors and inlet port are configured to have a negative seal transfer angle of, e.g.

Abstract: The present invention relates to novel compounds, pharmaceutical compositions containing such compounds and to their use in therapy.

Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.

Abstract: Techniques are disclosed herein for improving the accuracy of test data obtained outside of a clinical setting. Using the technologies described herein, different techniques can be utilized to analyze, score and adjust test data associated with one or more “at home” tests. In some examples, computing systems are utilized to generate quality scores indicating the accuracy of the test data associated with a particular biomarker. In other examples, an authorized user, such as a data manager can analyze the test data utilizing a user interface to generate scores and/or adjust the test data.

Abstract: Techniques are disclosed herein for generating personalized nutritional recommendations for foods available from one or more food sources. Using the technologies described herein, a programmatic analysis is performed on different data to predict values of personalized nutrition data, such as one or more target biomarkers, that are associated with an individual after eating the foods. Personalized nutritional recommendations for foods available from the food sources are then generated, using the predicted values, and provided to the individual. The predictions are based on data that is associated with the individual, such as microbiome data, triglycerides data, glucose data, nutritional data, questionnaire data, and the like. A prediction service can utilize a machine learning mechanism to generate the predicted personalized nutrition data. A nutrition service utilizes the predicted personalized nutrition data when generating the personalized nutritional recommendations.

Abstract: The present invention is directed to pyridyl derivatives which are bromodomain inhibitors, pharmaceutical compositions comprising the compounds and the use of the compounds or the compositions in the treatment of various diseases or conditions

Abstract: The present invention is directed to pyrazole derivatives, pharmaceutical compositions comprising the compounds and the use of the compounds or the compositions in the treatment of various diseases.

Abstract: Systems and methods that permit the querying of encrypted data in a cryptographically-secure manner. Generally, data that has been encrypted cannot be queried using plaintext terms because it is in ciphertext. Accordingly, use of filters that correspond to the encrypted data and are generated by multiple parties permits querying of the data without decrypting the data or compromising the security of the encrypted data or of the queries against that data.

Abstract: The systems and methods described herein assist persons with the use of computers based on eye gaze, and allow such persons to control such computing systems using various eye trackers. The systems and methods described herein use eye trackers to control cursor (or some other indicator) positioning on an operating system using the gaze location reported by the eye tracker. The systems and methods described herein utilize an interaction model that allows control of a computer using eye gaze and dwell. The data from eye trackers provides a gaze location on the screen. The systems and methods described herein control a graphical user interface that is part of an operating system relative to cursor positioning and associated actions such as Left-Click, Right-Click, Double-Click, and the like. The interaction model presents appropriate user interfaces to navigate the user through applications on the computing system.

Abstract: Techniques are disclosed herein for using standardized meals and digital devices can be utilized outside a clinical setting to assist in determining/predicting one or more clinical states associated with one or more individuals. Using the technologies described herein, different techniques can be utilized to for using nutritional response measurements. For example, response measurements can be obtained for two fat meals instead of a single fat meal. Data associated with a circadian rhythm (e.g., sleep times, awake times) can also be utilized to improve the accuracy of the measured biomarkers. In other examples, biome data and other data can be utilized.

Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy

Abstract: Techniques are disclosed herein for improving the accuracy of nutritional responses measured in a non-clinical setting. Using the technologies described herein, different techniques can be utilized to improve the accuracy of test data associated with one or more “at home” tests. In some examples, more than one test is utilized to improve the accuracy of test data associated with a particular biomarker. In other examples, a data accuracy service can programmatically analyze data received from an individual and determine whether the data is accurate. In some examples, a computing device is utilized to assist in determining what food item(s) are consumed, as well as determine whether a test protocol was followed.

Abstract: The present disclosure describes a therapeutic ultrasound system configured to adaptively transmit ultrasound pulses toward microbubbles in a treatment region to remove an occlusion. In some examples, the system may include a treatment pulse unit configured to transmit an ultrasound pulse to a treatment region of a subject, the treatment region including a plurality of microbubbles. An echo detection unit may be configured to receive one or more echoes responsive to the ultra sound pulse. In some examples, the system may also include a data processor configured to identify, using data associated with the echoes, at least one echo signature indicative of a dynamic state of the microbubbles in response to the ultrasound pulse. A controller may be configured to adjust one or more parameters of an additional ultrasound pulse transmitted to the treatment region via the treatment pulse unit based on the at least one echo signature.

Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.