Patents by Inventor Jonathan Thomas

Jonathan Thomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-OXO-1,2-dihydropyridine-3,5-dicarboxamide compounds as bromodomain inhibitors
    Patent number: 10471050
    Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.
    Type: Grant
    Filed: October 3, 2016
    Date of Patent: November 12, 2019
    Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED
    Inventors: Stephen John Atkinson, Emmanuel Hubert Demont, Lee Andrew Harrison, Thomas George Christopher Hayhow, Matthew J. Lindon, Alexander G. Preston, Jonathan Thomas Seal, Ian David Wall, Robert J. Watson, James Michael Woolven
  • ULTRASONIC SONOTHROMBOLYSIS TREATMENT PLANNING
    Publication number: 20190329075
    Abstract: An ultrasound system utilizes an array transducer to perform sonothrombolysis treatment. The system also produces a vascular map of flow characteristics in the vicinity of the therapy site in a subject. The vascular map is used to formulate a treatment plan which includes the number, focusing, timing, and steering of beams of a pattern of therapy beams transmitted during a transmission interval. Formulation of the treatment plan considers factors such as the direction of microbubble flow toward a therapy site, the flow velocity, the spacing between successive therapy beam transmissions, the number of therapy beams needed to “paint” a therapy region, and grating lobe locations, many of which can be determined from the vascular map.
    Type: Application
    Filed: December 6, 2017
    Publication date: October 31, 2019
    Inventors: JONATHAN THOMAS SUTTON, RALF SEIP, WILLIAM TAO SHI, JEFFRY EARL POWERS
  • Compounds and methods for treating cancer, neurological disorders, ethanol withdrawal, anxiety, depression, and neuropathic pain
    Patent number: 10450275
    Abstract: Provided herein, inter alia, are compounds and methods of treating diseases including cancer, neurological disease, alcohol withdrawal, depression and anxiety, and neuropathic pain.
    Type: Grant
    Filed: December 22, 2015
    Date of Patent: October 22, 2019
    Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Stephen F. Martin, James J. Sahn, Luisa Scott, Jonathan Thomas Pierce-Shimomura
  • Pyridinone dicarboxamide for use as bromodomain inhibitors
    Patent number: 10428026
    Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: October 1, 2019
    Assignee: GlaxoSmithKline Intellectual Property (No.2) Limited
    Inventors: Stephen John Atkinson, Helen Elizabeth Aylott, Anthony William James Cooper, Emmanuel Hubert Demont, Lee Andrew Harrison, Thomas George Christopher Hayhow, Matthew J. Lindon, Alexander G. Preston, Jonathan Thomas Seal, Ian David Wall, Robert J. Watson, James Michael Woolven
  • EXERCISE DEVICE
    Publication number: 20190290957
    Abstract: An exercise device is described. An exercise device including a body, the body having a top, a bottom, a first end located at one edge of the body, a second end located at an opposite end of the body, and first and second sides extending between the first and second ends; a first axle connected to a first wheel, the first axle also connected to the body proximate the first end at a first hub; a first spring having a first spring end, the first spring positioned at least partially within the first axle, with the first spring end slidably connected to one of the first wheel and the first hub at a first junction, wherein the first junction is configured to convey torque between the one of the first hub and the first wheel and the first spring end.
    Type: Application
    Filed: June 10, 2019
    Publication date: September 26, 2019
    Applicant: MILLZ, Inc.
    Inventors: Soren Mills, Jessica Mills, Jonathan Thomas Johnson
  • Systems, Methods, and Devices for Synchronization of Vehicle Data with Recorded Audio
    Publication number: 20190289255
    Abstract: A method for post-processing to synchronize audio data with vehicle data includes generating an artificial sound data based on time-series vehicle data. The method includes determining an offset that maximizes cross-correlation between the artificial sound data and recorded audio data. The method also includes shifting one or more of the time-series data and the recorded audio data relative to each other in time based on the offset. The shift may be used to generate or render a synchronized set of time-series data and recorded audio data.
    Type: Application
    Filed: June 7, 2019
    Publication date: September 19, 2019
    Inventor: Jonathan Thomas Mullen
  • Route Generation Using Road Lane Line Quality
    Publication number: 20190277644
    Abstract: A method for routing a vehicle includes determining, based on roadway section information for two or more potential driving routes for a vehicle, a first route along which a driver assistance feature or an automated driving feature will not be available and a second route along which the driver assistance feature or the automated driving feature will be available. The method further includes providing navigation instructions for the second route to a driver or control system.
    Type: Application
    Filed: May 24, 2019
    Publication date: September 12, 2019
    Inventors: Brett Stephens, Jonathan Thomas Mullen, Shane Elwart
  • Autonomous Vehicle Simulation And Testing
    Publication number: 20190278698
    Abstract: A method for providing simulation testing. The method may include receiving a customer request to generate a virtual environment for testing a robot of the customer. The virtual environment may be automatically generated by a service provider in accordance with the request. The customer may interface with the virtual environment of the service provider to iteratively test the robot in the virtual environment. This testing may generate simulation results that reflect interactions between the robot and the virtual environment. The simulation results may be communicated from the service provider to the customer. A corresponding system and computer program product are also disclosed herein.
    Type: Application
    Filed: March 7, 2019
    Publication date: September 12, 2019
    Inventors: Warren Ahner, Jonathan Thomas Mullen
  • High-Value Test Generation For Autonomous Vehicles
    Publication number: 20190271614
    Abstract: A method for generating high-value test scenarios for autonomous vehicles. The method includes identifying multiple scenarios, each associated with a location on a road network. An injury value may be determined for each of the scenarios, and the scenarios and their associated injury values may be stored in a database. A desired location for testing an autonomous vehicle may be selected. At least one of the scenarios associated with the desired location and having an associated injury value that exceeds a predetermined threshold may be identified in the database. A virtual reality test environment may then be generated for the autonomous vehicle based on the at least one scenario. A corresponding system and computer program product are also disclosed and claimed herein.
    Type: Application
    Filed: March 1, 2019
    Publication date: September 5, 2019
    Inventors: Warren Ahner, Jonathan Thomas Mullen
  • Systems, methods, and devices for synchronization of vehicle data with recorded audio
    Patent number: 10397516
    Abstract: A method for post-processing to synchronize audio data with vehicle data includes generating an artificial sound data based on time-series vehicle data. The method includes determining an offset that maximizes cross-correlation between the artificial sound data and recorded audio data. The method also includes shifting one or more of the time-series data and the recorded audio data relative to each other in time based on the offset. The shift may be used to generate or render a synchronized set of time-series data and recorded audio data.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: August 27, 2019
    Assignee: FORD GLOBAL TECHNOLOGIES, LLC
    Inventor: Jonathan Thomas Mullen
  • GENERATING PREDICTED VALUES OF BIOMARKERS FOR SCORING FOOD
    Publication number: 20190251861
    Abstract: Techniques are disclosed herein for generating personalized nutritional recommendations using predicted values of target biomarkers. Using the technologies described herein, a programmatic analysis is performed on different data to predict values of target biomarkers that are associated with an individual. Personalized nutritional recommendations are then generated, using the predicted values, and provided to the individual. The predictions are based on data that is associated with the individual, such as microbiome data, ketone data, glucose data, nutritional data, questionnaire data, and the like. A prediction service can utilize a machine learning mechanism to generate the predicted value of the target biomarkers. A nutrition service utilizes the predicted value of the target biomarkers when generating the personalized nutritional recommendations.
    Type: Application
    Filed: February 12, 2018
    Publication date: August 15, 2019
    Inventors: Jonathan Thomas Wolf, George Hadjigeorgiou, Richard James Davies
  • GENERATING PERSONALIZED NUTRITIONAL RECOMMENDATIONS USING PREDICTED VALUES OF BIOMARKERS
    Publication number: 20190252058
    Abstract: Techniques are disclosed herein for generating personalized nutritional recommendations using predicted values of target biomarkers. Using the technologies described herein, a programmatic analysis is performed on different data to predict values of target biomarkers that are associated with an individual. Personalized nutritional recommendations are then generated, using the predicted values, and provided to the individual. The predictions are based on data that is associated with the individual, such as microbiome data, ketone data, glucose data, nutritional data, questionnaire data, and the like. A prediction service can utilize a machine learning mechanism to generate the predicted value of the target biomarkers. A nutrition service utilizes the predicted value of the target biomarkers when generating the personalized nutritional recommendations.
    Type: Application
    Filed: February 12, 2018
    Publication date: August 15, 2019
    Inventors: Jonathan Thomas Wolf, George Hadjigeorgiou, Richard James Davies
  • Method and system for battery management
    Patent number: 10374444
    Abstract: A battery management system is provided that controls at least a stack of battery cells. The battery management system may detect stack voltage and current. Characteristics of each battery cell in the stack may be monitored. The battery management system may detect ground fault within the stack of battery cells. Communication breakdown and/or failure in the battery management system may also be detected.
    Type: Grant
    Filed: May 16, 2016
    Date of Patent: August 6, 2019
    Assignee: ELITE POWER INNOVATIONS, LLC.
    Inventors: Michael Alan Worry, John Ellis Corman, Stefan Erik Janhunen, Jonathan Thomas Malton, Nathanael Dimitro Wennyk
  • Pyridinone dicarboxamide for use as bromodomain inhibitors
    Patent number: 10370356
    Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy
    Type: Grant
    Filed: September 20, 2016
    Date of Patent: August 6, 2019
    Assignee: GlaxoSmithKline Intellectual Property (No. 2) Limited
    Inventors: Stephen John Atkinson, Emmanuel Hubert Demont, Lee Andrew Harrison, Thomas George Christopher Hayhow, David House, Matthew J. Lindon, Alexander G. Preston, Jonathan Thomas Seal, Ian David Wall, Robert J. Watson, James Michael Woolven
  • Hydrogen peroxide catalyst
    Patent number: 10364151
    Abstract: A catalyst for decomposing high-concentration hydrogen peroxide comprises an active layer on a carrier comprising gamma-phase alumina. The carrier can also comprise aluminum, with the gamma-phase alumina forming a passivating layer on the surface of the aluminum. The active layer can comprise platinum. Apparatus for decomposing hydrogen peroxide can include the catalyst in a decomposition chamber arranged to receive hydrogen peroxide. The apparatus can be used as a thruster, comprising a nozzle arranged to generate thrust by directing exhaust gases in a specific direction. For example, the thruster can be a monopropellant, bipropellant, or hybrid thruster. In other embodiments, the apparatus can be used as a gas generator or a fuel cell.
    Type: Grant
    Filed: September 8, 2014
    Date of Patent: July 30, 2019
    Assignee: Airbus Defence and Space Limited
    Inventors: Jonathan Thomas William Wynn, Anthony Joseph Musker
  • Route generation using road lane line quality
    Patent number: 10345111
    Abstract: A method for routing a vehicle includes determining, based on roadway section information for two or more potential driving routes for a vehicle, a first route along which a driver assistance feature or an automated driving feature will not be available and a second route along which the driver assistance feature or the automated driving feature will be available. The method further includes providing navigation instructions for the second route to a driver or control system.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: July 9, 2019
    Assignee: FORD GLOBAL TECHNOLOGIES, LLC
    Inventors: Brett Stephens, Jonathan Thomas Mullen, Shane Elwart
  • PYRIDINE DICARBOXAMIDE DERIVATIVES AS BROMODOMAIN INHIBITORS
    Publication number: 20190202786
    Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.
    Type: Application
    Filed: May 22, 2017
    Publication date: July 4, 2019
    Inventors: Stephen John ATKINSON, Emmanuel Hubert DEMONT, Lee Andrew HARRISON, Etienne LEVERNIER, Alexander G. PRESTON, Jonathan Thomas SEAL, Ian David WALL, Robert J. WATSON, James Michael WOOLVEN
  • BENZO[B]FURANS AS BROMODOMAIN INHIBITORS
    Publication number: 20190151279
    Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.
    Type: Application
    Filed: April 5, 2017
    Publication date: May 23, 2019
    Inventors: Stephen John ATKINSON, Emmanuel Hubert DEMONT, Lee Andrew HARRISON, Alexander G. PRESTON, Jonathan Thomas SEAL, Ian David WALL, Robert J. WATSON, James Michael WOOLVEN
  • Perception-based speed limit estimation and learning
    Patent number: 10275664
    Abstract: Systems, methods, and devices for estimating a speed limit are disclosed herein. A system for estimating a speed limit includes one or more perception sensors, an arbitrated speed component, an attribute component, an estimator component, and a notification component. The one or more perception sensors are configured to generate perception data about a region near a vehicle. The arbitrated speed component is configured to determine that a high confidence or arbitrated speed limit is not available. The attribute component is configured to detect one or more environmental attributes based on the perception data. The estimator component is configured to determine an estimated speed limit based on the environmental attributes. The notification component is configured to provide the estimated speed limit to an automated driving system or driver assistance system of the vehicle.
    Type: Grant
    Filed: July 6, 2017
    Date of Patent: April 30, 2019
    Assignee: FORD GLOBAL TECHNOLOGIES, LLC
    Inventor: Jonathan Thomas Mullen
  • PYRIDYL DERIVATIVES AS BROMODOMAIN INHIBITORS
    Publication number: 20190119248
    Abstract: The present invention relates to compounds of formula (I) and salts thereof, pharmaceutical compositions containing such compounds and to their use in therapy.
    Type: Application
    Filed: April 5, 2017
    Publication date: April 25, 2019
    Applicant: GlaxoSmithKline Intellectual Property (No. 2) Limited
    Inventors: Stephen John ATKINSON, Emmanuel Hubert DEMONT, Lee Andrew HARRISON, Etienne LEVERNIER, Alexander G. PRESTON, Jonathan Thomas SEAL, Ian David WALL, Robert J. WATSON, James Michael WOOLVEN