Abstract: A fine object separation device includes: a first channel in which a subject solution including a plurality of different fine objects having a size of 1 micrometer or less flows in from one side and flows to the other side; and a second channel that communicates with a first wall surface of the first channel at an angle greater than 0°, parallel to the flow direction of the subject solution, and less than 90°, perpendicular to the flow direction of the subject solution, wherein the second channel merges a buffer solution with the first channel.

Abstract: The present invention relates to a method for modifying the surface of a polymer substrate. Specifically, the present invention provides a method for modifying the surface of a polymer substrate using a plasma treatment, a hydrophilic primer and a coating agent including a hydrophobic fluorine compound.

Abstract: A cell culture kit is provided. The cell culture kit allows a cultured cell to be easily separated when the cell is cultured and separates a cell without separate trypsinization for subculture.

Abstract: Nucleic acid from cells and viruses sampled from a variety of environments may purified and expressed utilizing microfluidic techniques. Individual or small groups of cells or viruses may be isolated in microfluidic chambers by dilution, sorting, and/or segmentation. The isolated cells or viruses may be lysed directly in the microfluidic chamber, and the resulting nucleic acid purified by exposure to affinity beads. Subsequent elution of the purified nucleic acid may be followed by ligation and cell transformation, all within the same microfluidic chip. Cell isolation, lysis, and nucleic acid purification may be performed utilizing a highly parallelized microfluidic architecture to construct gDNA and cDNA libraries.

Abstract: A particle separation apparatus, according to an embodiment of the present invention, may comprise: a first input flow path into which a first fluid containing a plurality of particles of different sizes is introduced; a second input flow path into which a second fluid not containing particles is introduced; a connection flow path and the second input flow path so that a third fluid in which the first fluid and the second fluid are mixed movies; a plurality of discharge flow paths where the plurality of particles which come out through the other end of the connection flow path are separated and discharged according to the size of the particles; and a branch flow path where at least a part of the third fluid which comes out through the other end of the connection flow path is discharged.

Abstract: The present invention relates to a method for modifying the surface of a polymer substrate. Specifically, the present invention provides a method for modifying the surface of a polymer substrate using a plasma treatment, a hydrophilic primer and a coating agent including a hydrophobic fluorine compound.

Abstract: Nucleic acid from cells and viruses sampled from a variety of environments may purified and expressed utilizing microfluidic techniques. Individual or small groups of cells or viruses may be isolated in microfluidic chambers by dilution, sorting, and/or segmentation. The isolated cells or viruses may be lysed directly in the microfluidic chamber, and the resulting nucleic acid purified by exposure to affinity beads. Subsequent elution of the purified nucleic acid may be followed by ligation and cell transformation, all within the same microfluidic chip. Cell isolation, lysis, and nucleic acid purification may be performed utilizing a highly parallelized microfluidic architecture to construct gDNA and cDNA libraries.

Abstract: A cell culture kit is provided. The cell culture kit allows a cultured cell to be easily separated when the cell is cultured and separates a cell without separate trypsinization for subculture.

Abstract: Nucleic acid from cells and viruses sampled from a variety of environments may purified and expressed utilizing microfluidic techniques. In accordance with one embodiment of the present invention, individual or small groups of cells or viruses may be isolated in microfluidic chambers by dilution, sorting, and/or segmentation. The isolated cells or viruses may be lysed directly in the microfluidic chamber, and the resulting nucleic acid purified by exposure to affinity beads. Subsequent elution of the purified nucleic acid may be followed by ligation and cell transformation, all within the same microfluidic chip. In one specific application, cell isolation, lysis, and nucleic acid purification may be performed utilizing a highly parallelized microfluidic architecture to construct gDNA and cDNA libraries.

Abstract: A particle separation apparatus, according to an embodiment of the present invention, may comprise: a first input flow path into which a first fluid containing a plurality of particles of different sizes is introduced; a second input flow path into which a second fluid not containing particles is introduced; a connection flow path and the second input flow path so that a third fluid in which the first fluid and the second fluid are mixed movies; a plurality of discharge flow paths where the plurality of particles which come out through the other end of the connection flow path are separated and discharged according to the size of the particles; and a branch flow path where at least a part of the third fluid which comes out through the other end of the connection flow path is discharged.

Abstract: Nucleic acid from cells and viruses sampled from a variety of environments may purified and expressed utilizing microfluidic techniques. In accordance with one embodiment of the present invention, individual or small groups of cells or viruses may be isolated in microfluidic chambers by dilution, sorting, and/or segmentation. The isolated cells or viruses may be lysed directly in the microfluidic chamber, and the resulting nucleic acid purified by exposure to affinity beads. Subsequent elution of the purified nucleic acid may be followed by ligation and cell transformation, all within the same microfluidic chip. In one specific application, cell isolation, lysis, and nucleic acid purification may be performed utilizing a highly parallelized microfluidic architecture to construct gDNA and cDNA libraries.

Abstract: Nucleic acid from cells and viruses sampled from a variety of environments may purified and expressed utilizing microfluidic techniques. In accordance with one embodiment of the present invention, individual or small groups of cells or viruses may be isolated in microfluidic chambers by dilution, sorting, and/or segmentation. The isolated cells or viruses may be lysed directly in the microfluidic chamber, and the resulting nucleic acid purified by exposure to affinity beads. Subsequent elution of the purified nucleic acid may be followed by ligation and cell transformation, all within the same microfluidic chip. In one specific application, cell isolation, lysis, and nucleic acid purification may be performed utilizing a highly parallelized microfluidic architecture to construct gDNA and cDNA libraries.

Abstract: An apparatus for opening and closing a trunk for a vehicle, may include a motor unit equipped with a motor, an inner tube provided outside the motor unit to surround the motor unit, with a plurality of protrusions protruding from an outer circumference of the inner tube, an outer tube provided outside the inner tube to surround the inner tube and including a threaded groove being indented along an inner circumference of the outer tube, a bar-shaped spindle having a threaded portion on an outer circumference thereof, and coupled to the motor unit to cause the threaded portion of the spindle to engage with the threaded groove of the outer tube when the motor may be rotated, thus allowing the spindle to perform translation simultaneously with rotation, and an elastic member-wound on an outer circumference of the outer tube.

Abstract: Nucleic acid from cells and viruses sampled from a variety of environments may purified and expressed utilizing microfluidic techniques. In accordance with one embodiment of the present invention, individual or small groups of cells or viruses may be isolated in microfluidic chambers by dilution, sorting, and/or segmentation. The isolated cells or viruses may be lysed directly in the microfluidic chamber, and the resulting nucleic acid purified by exposure to affinity beads. Subsequent elution of the purified nucleic acid may be followed by ligation and cell transformation, all within the same microfluidic chip. In one specific application, cell isolation, lysis, and nucleic acid purification may be performed utilizing a highly parallelized microfluidic architecture to construct gDNA and cDNA libraries.

Abstract: An apparatus for opening and closing a trunk for a vehicle, may include a motor unit equipped with a motor, an inner tube provided outside the motor unit to surround the motor unit, with a plurality of protrusions protruding from an outer circumference of the inner tube, an outer tube provided outside the inner tube to surround the inner tube and including a threaded groove being indented along an inner circumference of the outer tube, a bar-shaped spindle having a threaded portion on an outer circumference thereof, and coupled to the motor unit to cause the threaded portion of the spindle to engage with the threaded groove of the outer tube when the motor may be rotated, thus allowing the spindle to perform translation simultaneously with rotation, and an elastic member-wound on an outer circumference of the outer tube.

Abstract: Nucleic acid from cells and viruses sampled from a variety of environments may purified and expressed utilizing microfluidic techniques. In accordance with one embodiment of the present invention, individual or small groups of cells or viruses may be isolated in microfluidic chambers by dilution, sorting, and/or segmentation. The isolated cells or viruses may be lysed directly in the microfluidic chamber, and the resulting nucleic acid purified by exposure to affinity beads. Subsequent elution of the purified nucleic acid may be followed by ligation and cell transformation, all within the same microfluidic chip. In one specific application, cell isolation, lysis, and nucleic acid purification may be performed utilizing a highly parallelized microfluidic architecture to construct gDNA and cDNA libraries.

Abstract: Devices and methods use an integrated microfluidic system that has the capability of realizing a wide range of accurate dilutions in a logarithmic way through semi-direct dilution of samples inside a chip. The device for dose response analysis is able to contain a first fluid source on a microfluidic chip, wherein the first fluid source comprises a drug, a second fluid source on the microfluidic chip, a mixing area on the microfluidic chip fluidically coupling with the first and the second fluidic source, and a detection area coupling with the mixing area for drug information detection using a detection system.

Abstract: A programmable fluidic device for generating droplets with resolutions of micrometer in size and milliseconds in generation timing is provided. The programmable fluidic device has a valve forming a droplet cutter, which contains a fluid deflectable membrane capable of controlling the flow of a dispensing fluid from a fluidic dispensing channel. The programmable fluidic device is able to perform temporal control over the droplet generation independent from the size control.

Abstract: A method of fabricating an image sensor may include providing a substrate including light-receiving and non-light-receiving regions; forming a plurality of gates on the non-light-receiving region; ion-implanting a first-conductivity-type dopant into the light-receiving region to form a first dopant region of a pinned photodiode; primarily ion-implanting a second-conductivity-type dopant, different from the first-conductivity-type dopant, into an entire surface of the substrate, using the gates as a first mask; forming spacers on both side walls of the gates; and secondarily ion-implanting the second-conductivity-type dopant into the entire surface of the substrate, using the plurality of gates including the spacers as a second mask, to complete a second dopant region of the pinned photodiode.

Abstract: Devices and methods use an integrated microfluidic system that has the capability of realizing a wide range of accurate dilutions in a logarithmic way through semi-direct dilution of samples inside a chip. The device for dose response analysis is able to contain a first fluid source on a microfluidic chip, wherein the first fluid source comprises a drug, a second fluid source on the microfluidic chip, a mixing area on the microfluidic chip fluidically coupling with the first and the second fluidic source, and a detection area coupling with the mixing area for drug information detection using a detection system.