Patents by Inventor Juhani Saarinen
Juhani Saarinen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8546353Abstract: The present invention relates to a combination of a hyaluronan oligomer and/or polymer and a factor capable of mobilizing stem cells. The present invention also relates to a method for altering the relative amounts of blood cells and/or the types of blood cells in a subject by administering the combination to the subject. Further, the present invention relates to a method for mobilizing stem cells to the bloodstream of a subject by administering the combination to the subject. Additionally, the present invention relates to a hyaluronan oligomer and/or polymer.Type: GrantFiled: May 6, 2011Date of Patent: October 1, 2013Assignee: Glykos Finland OyInventors: Johanna Nystedt, Heidi Anderson, Tero Satomaa, Jari Natunen, Jari Helin, Juhani Saarinen
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Patent number: 8313912Abstract: The invention concerns a method for diagnosing cancer in a biological sample by determining the presence of a LacdiNAc oligosaccharide sequence. The invention can be used for diagnostic agents, pharmaceutical compositions, cancer vaccines, and antigenic carbohydrate substances. The presence of cancer and malignancies is determined by contacting the biological sample with a reagent that binds to the oligosaccharide sequence. This same method can also be used in the treatment of cancer and malignancies.Type: GrantFiled: August 16, 2002Date of Patent: November 20, 2012Assignee: Glykos Finland OyInventors: Juhani Saarinen, Jari Helin, Tero Satomaa
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Publication number: 20120166696Abstract: For handling a user input, an indication of a current state is received from a processor. When a user input is detected, it is determined whether the user input matches a criterion that is defined for the current state. An interrupt request to the processor is generated if it is determined that the user input matches the criterion defined for the current state.Type: ApplicationFiled: June 26, 2009Publication date: June 28, 2012Applicant: NOKIA CORPORATIONInventors: Janne Jouni Kallio, Kari Matias Severinkangas, Ari Veijo Pentti Helaakoski, Pertti Juhani Saarinen
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Publication number: 20110306128Abstract: The invention relates to a method for culturing human embryonic stem cells (hESCs) and/or induced pluripotent stem (iPS) cells on a lectin. The invention relates also to the use of a lectin in a method for culturing human embryonic stem cells (hESCs) and/or induced pluripotent stem (iPS) celts and a culture medium composition containing a lectin attached on the culturing plates.Type: ApplicationFiled: July 13, 2009Publication date: December 15, 2011Applicants: GLYKOS FINLAND OY, SUOMEN PUNAINEN RISTI VERIPALVELUInventors: Ulla Impola, Minna Tiittanen, Milla Mikkola, Jukka Partanen, Jari Natunen, Tero Satomaa, Juhani Saarinen
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Publication number: 20110274646Abstract: The present invention relates to a combination of a hyaluronan oligomer and/or polymer and a factor capable of mobilizing stem cells. The present invention also relates to a method for altering the relative amounts of blood cells and/or the types of blood cells in a subject by administering the combination to the subject. Further, the present invention relates to a method for mobilizing stem cells to the bloodstream of a subject by administering the combination to the subject. Additionally, the present invention relates to a hyaluronan oligomer and/or polymer.Type: ApplicationFiled: May 6, 2011Publication date: November 10, 2011Applicants: Glykos Finland Oy, Suomen Punainen Risti VeripalveluInventors: Johanna Nystedt, Heidi Anderson, Tero Satomaa, Jari Natunen, Jari Helin, Juhani Saarinen
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Publication number: 20110250235Abstract: The present invention is directed to a method of production of an immunostimulatory composition having a saccharide fraction, the method including the steps of hydrolyses of yeast cells and recovering the soluble fraction. The saccharide fraction having composition thus obtained may be incorporated as a food or beverage component or be used as a pharmaceutical for treatment of specific conditions.Type: ApplicationFiled: December 18, 2009Publication date: October 13, 2011Applicant: GLYKOS FINLAND OYInventors: Juhani Saarinen, Ritva Niemela, Jari Helin, Jari Natunen, Jukka Hiltunen
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Publication number: 20100184150Abstract: The present invention is directed to a novel saccharide composition isolated from a yeast culture. The invention is also directed to yeast cell based saccharide composition with increased water-solubility. The saccharide compositions disclosed in the invention can be used as nutritional or pharmaceutical additives or as part of nutritional or pharmaceutical composition in order to promote the health of an animal or human subject to which said composition is administered. The invention is also directed to methods of producing said saccharide compositions.Type: ApplicationFiled: June 13, 2008Publication date: July 22, 2010Applicants: GLYKOS FINLAND OY, SUOMEN REHU OYInventors: Ritva Niemela, Juhani Saarinen, Jari Helin, Janica Wakkinen
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Publication number: 20100120142Abstract: The invention relates to a method for culturing human embryonic stem cells (hESCs) with a lectin. The invention relates also to the use of a lectin in a method for culturing human embryonic stem cells (hESCs) and a culture medium composition containing a lectin.Type: ApplicationFiled: July 11, 2008Publication date: May 13, 2010Applicants: SUOMEN PUNAINEN RISTI VERIPALVELU, Glykos Finland OyInventors: Ulla Impola, Minna Tiittanen, Milla Mikkola, Jukka Partanen, Jari Natunen, Tero Satomaa, Juhani Saarinen
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Publication number: 20100068806Abstract: The present invention provides methods and materials to modulate and grow stem cells by contacting stem cells with a binder recognizing terminal glycan structures of stem cells. The modulation can be morphological change, change in differentiation status, biological status or adherence. The materials provided in the present invention are also useful to screen such a binding agents and binders.Type: ApplicationFiled: January 18, 2008Publication date: March 18, 2010Applicants: SUOMEN PUNAINEN RISTI, VERIPALVELU, Glykos Finland Ltd.Inventors: Jarmo Laine, Tero Satomaa, Jari Natunen, Annamari Heiskanen, Maria Blomqvist, Anne Olonen, Juhani Saarinen, Sari Tiitiene, Ulla Impola, Milla Mikkola, Leena Valmu, Minna Tiittanen
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Publication number: 20100055710Abstract: The invention describes methods for production of novel composition of glycans, glycomes, from human multipotent stem cells. The invention is further directed to methods for modifying the glycomes and analysis of the glycomes and the modified glycomes. Furthermore the invention is directed to stem cells carrying the modified glycomes on their surfaces.Type: ApplicationFiled: July 11, 2006Publication date: March 4, 2010Applicants: SUOMEN PUNAINEN RISTI, VERIPALVELU, GLYKOS FINLAND OYInventors: Tero Satomaa, Jari Natunen, Jarmo Laine, Annamari Heiskanen, Maria Blomqvist, Anne Olonen, Juhani Saarinen, Taina Jaatinen, Ulla Impola, Milla Mikkola, Heidi Anderson
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Publication number: 20100047827Abstract: The invention describes reagents and methods for specific binders to glycan structures of stem cells. Furthermore the invention is directed to screening of additional binding reagents against specific glycan epitopes on the surfaces of the stem cells. The preferred binders of the glycans structures includes proteins such as enzymes, lectins and antibodies.Type: ApplicationFiled: January 18, 2008Publication date: February 25, 2010Applicants: SUOMEN PUNAINEN RISTI, VERIPALVELU, GLYKOS FINLAND LTD.Inventors: Jarmo Laine, Tero Satomaa, Jari Natunen, Annamari Heiskanen, Maria Blomqvist, Anne Olonen, Juhani Saarinen, Sari Titinen, Ulla Impola, Olli Aitio, Leena Valmu, Ulla Impola, Olli Aitio, Leena Valmu, Suvi Natunen, Hanna Salo
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Publication number: 20100028913Abstract: The invention describes reagents and methods for specific binders to glycan structures of stem cells. Furthermore the invention is directed to screening of additional binding reagents against specific glycan epitopes on the surfaces of the stem cells. The preferred binders of the glycans structures includes proteins such as enzymes, lectins and antibodies.Type: ApplicationFiled: January 18, 2008Publication date: February 4, 2010Applicants: SUOMEN PUNAINEN RISTI, VERIPALVELU, Glykos Finland Ltd.Inventors: Jarmo Laine, Tero Satomaa, Jari Natunen, Annamari Heiskanen, Maria Blomqvist, Anne Olonen, Juhani Saarinen, Sari Titinen, Ulla Impola, Olli Aitio, Leena Valmu, Heidi Anderson, Virve Pitkänen, Jukka Partanen, Taina Jaatinen
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Publication number: 20100003699Abstract: The present invention reveals novel methods for producing novel carbohydrate compositions, glycomes, from animal tissues. The tissue substrate materials can be total tissue samples and fractionated tissue parts, or artificial models of tissues such as cultivated cell lines. The invention is further directed to the compositions and compositions produced by the methods according to the invention. The invention further represent methods for analysis of the glycomes, especially mass spectrometric methods.Type: ApplicationFiled: January 16, 2009Publication date: January 7, 2010Applicant: Glykos Finland Ltd.Inventors: Tero Satomaa, Jari Natunen, Annamari Heiskanen, Maria Blomqvist, Anne Olonen, Juhani Saarinen
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Publication number: 20090324617Abstract: The present invention describes glycans, which are specifically expressed by certain cancer cells, tumours and other malignant tissues. The present invention describes methods to detect cancer specific glycans as well as methods for the production of reagents binding to said glycans. The invention is also directed to the use of said glycans and reagents binding to them for the diagnostics of cancer and malignancies. Furthermore, the invention is directed to the use of said glycans and reagents binding to them for the treatment of cancer and malignancies. Moreover, the present invention comprises efficient methods to differentiate between malignant and benign tumors by analyzing glycan structures.Type: ApplicationFiled: January 22, 2009Publication date: December 31, 2009Applicant: Glykos Finland Ltd.Inventors: Tero Satomaa, Jari Natunen, Annamari Heiskanen, Anne Olonen, Noora Salovuori, Juhani Saarinen, Jari Helin
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Publication number: 20090317788Abstract: The present invention discloses a method of evaluating the status of a stem cell preparation comprising the step of detecting the presence of a glycan structure or a group of glycan structures in said preparation. The detection step can be performed by the use of a lectin specific to a glycan structure of interest.Type: ApplicationFiled: November 8, 2006Publication date: December 24, 2009Applicants: SUOMEN PUNAINEN RISTI, VERIPALVELU, Glykos Finland OyInventors: Jarmo Laine, Tero Satomaa, Jari Natunen, Annamari Heiskanen, Marie Blomqvist, Anne Olonen, Juhani Saarinen, Taina Jaatinen, Ulla Impola, Milla Mikkaola
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Publication number: 20090317834Abstract: The invention describes novel compositions of glycans, glycomes, from human embryonic stem cells, and especially novel subcompositions of the glycomes with specific monosaccharide compositions and glycan structures. The invention is further directed to methods for modifying the glycomes and analysis of the glycomes and the modified glycomes. Furthermore, the invention is directed to stem cells carrying the modified glycomes on their surfaces. The glycomes are preferably analysed by profiling methods able to detect reproducibly and quantitatively numerous individual glycan structures at the same time. The most preferred type of the profile is a mass spectrometric profile. The invention specifically revealed novel target structures and is especially directed to the development of reagents recognizing the structures.Type: ApplicationFiled: June 29, 2007Publication date: December 24, 2009Inventors: Jarmo Laine, Tero Satomaa, Jari Natunen, Annamari Heiskanen, Juhani Saarinen, Taina Jaatinen, Milla Mikkola, Suvi Natunen
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Publication number: 20090160778Abstract: An apparatus, method and computer program product are provided for using varying numbers of tactile inputs to manipulate different features of an electronic device. In particular, varying numbers of tactile inputs resulting from a user touching the electronic device touchscreen or touchpad may be used in order to adjust the speed of movement of an image displayed on the electronic device. Varying numbers of tactile inputs may likewise be used to adjust in various manners an adjustable feature represented by an icon displayed on the electronic device display screen. Finally, varying numbers of tactile inputs may further be used in order to unlock an electronic device in a secure, yet simple, manner.Type: ApplicationFiled: December 19, 2007Publication date: June 25, 2009Inventors: Juha Harri-Pekka Nurmi, Kaj Juhani Saarinen, Tero Juhani Rautanen
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Publication number: 20090162938Abstract: The invention describes methods for production of novel composition of glycans, glycomes, from human multipotent stem cells. The invention is further directed to methods for modifying the glycomes and analysis of the glycomes and the modified glycomes. Furthermore the invention is directed to stem cells carrying the modified glycomes on their surfaces.Type: ApplicationFiled: November 8, 2006Publication date: June 25, 2009Applicants: SUOMEN PUNAINEN RISTI,VERIPALVELU, GLYKOS FINLAND OYInventors: Jarmo Laine, Tero Satomaa, Jari Natunen, Annamari Heiskanen, Maria Blomqvist, Anne Olonen, Juhani Saarinen, Taina Jaatinen, Ulla Impola, Milla Mikkola
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Publication number: 20090117106Abstract: The present invention describes glycans, which are specifically expressed by certain cancer cells, tumours and other malignant tissues. The present invention describes methods to detect cancer specific glycans as well as methods for the production of reagents binding to said glycans. The invention is also directed to the use of said glycans and reagents binding to them for the diagnostics of cancer and malignancies. Furthermore, the invention is directed to the use of said glycans and reagents binding to them for the treatment of cancer and malignancies. Moreover, the present invention comprises efficient methods to differentiate between malignant and benign tumors by analyzing glycan structures.Type: ApplicationFiled: July 20, 2006Publication date: May 7, 2009Applicant: Glykos Finland OyInventors: Tero Satomaa, Jari Natunen, Annamari Heiskanen, Anne Olonen, Juhani Saarinen, Noora Salovuori, Jari Helin
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Publication number: 20090104603Abstract: The present invention reveals novel methods for producing novel carbohydrate compositions, glycomes, from animal tissues. The tissue substrate materials can be total tissue samples and fractionated tissue parts, or artificial models of tissues such as cultivated cell lines. The invention is further directed to the compositions and compositions produced by the methods according to the invention. The invention further represent methods for analysis of the glycomes, especially mass spectrometric methods.Type: ApplicationFiled: July 11, 2006Publication date: April 23, 2009Applicant: Glykos Finland OyInventors: Tero Satomaa, Jari Natunen, Annamari Heiskanen, Maria Blomqvist, Anne Olonen, Juhani Saarinen