Patents by Inventor Leonardo De Maria

Leonardo De Maria has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Glucoamylase variants and polynucleotides encoding same
    Patent number: 9765318
    Abstract: The present invention relates to glucoamylase variants having improved thermostability. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: November 29, 2016
    Date of Patent: September 19, 2017
    Assignee: NOVOZYMES A/S
    Inventors: Esben Peter Friis, Leonardo De Maria, Jesper Vind, Thomas A. Poulsen, Allan Svendsen, Steffen Danielsen, Rolf T. Lenhard, Henrik Friis-Madsen, Lars K. Skov
  • Dough with a Lipolytic Enzyme and/or Xylanase and a Monooxygenase
    Publication number: 20170188592
    Abstract: A method for preparing a dough or a baked product prepared from the dough which method comprises incorporating into the dough a lipolytic enzyme and/or a xylanase and an X143 polypeptide, wherein the X143 polypeptide is a monooxygenase.
    Type: Application
    Filed: July 6, 2015
    Publication date: July 6, 2017
    Applicant: Novozymes A/S
    Inventors: Henrik Lundkvist, Morten Tovborg, Leonardo De Maria, Chee-Leong Soong
  • Glucoamylase variants and polynucleotides encoding same
    Patent number: 9695406
    Abstract: The present invention relates to glucoamylase variants having increased thermostability. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: March 6, 2014
    Date of Patent: July 4, 2017
    Assignee: NOVOZYMES A/S
    Inventors: Esben P. Friis, Jesper Vind, Leonardo De Maria, Bjarne G. Hansen
  • Method of treating polyester textile
    Patent number: 9663804
    Abstract: The present invention relates to the use of glycosyl hydrolase family 61 polypeptides in the presence of cutinases for polyester textile manufacture as well as a textile composition comprising glycosyl hydrolase family 61 polypeptides and cutinases.
    Type: Grant
    Filed: July 18, 2013
    Date of Patent: May 30, 2017
    Assignee: Novozymes A/S
    Inventors: Weijian Lai, Ting Sun, Leonardo De Maria
  • Thermostable phytase variants
    Patent number: 9611469
    Abstract: The present invention relates to a method for producing phytase variants which has at least 74% identity to a phytase derived from Citrobacter braakii and comprises at least two additional disulfide bonds as compared to this phytase. These phytase variants have modified, preferably improved, properties, such as thermostability, temperature profile, pH profile, specific activity, performance in animal feed, reduced protease sensitiliby, and/or an modified glycosylation pattern. The invention also relates to the variants produced, DNA encoding these phytases, methods of their production, as well as the use thereof, e.g., in animal feed and animal feed additives.
    Type: Grant
    Filed: February 20, 2015
    Date of Patent: April 4, 2017
    Assignee: Novozymes A/S
    Inventors: Lars Kobberoee Skov, Leonardo De Maria, Tomoko Matsui
  • GLUCOAMYLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME
    Publication number: 20170073655
    Abstract: The present invention relates to glucoamylase variants having improved thermostability. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: November 29, 2016
    Publication date: March 16, 2017
    Applicant: NOVOZYMES A/S
    Inventors: Esben Peter Friis, Leonardo De Maria, Jesper Vind, Thomas A. Poulsen, Allan Svendsen, Steffen Danielsen, Rolf T. Lenhard, Henrik Friis-Madsen, Lars K. Skov
  • POLYPEPTIDES HAVING ORGANOPHOSPHOROUS HYDROLASE ACTIVITY
    Publication number: 20170073653
    Abstract: The present invention relates to isolated polypeptides having organophosphorous hydrolase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Application
    Filed: November 3, 2016
    Publication date: March 16, 2017
    Applicant: NOVOZYMES A/S
    Inventors: Bjarne Gram Hansen, Steffen Danielsen, Lars Kobberoee Skov, Leonardo De Maria, Julie Bille Rannes
  • Glucoamylase variants and polynucleotides encoding same
    Patent number: 9540624
    Abstract: The present invention relates to glucoamylase variants having improved thermostability. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: April 26, 2016
    Date of Patent: January 10, 2017
    Assignee: NOVOZYMES A/S
    Inventors: Esben Peter Friis, Leonardo De Maria, Jesper Vind, Thomas A. Poulsen, Allan Svendsen, Steffen Danielsen, Rolf T. Lenhard, Henrik Friis-Madsen, Lars K. Skov
  • Peroxygenase Variants
    Publication number: 20160376566
    Abstract: The present invention relates to peroxygenase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: December 1, 2014
    Publication date: December 29, 2016
    Applicant: Novozymes A/S
    Inventors: Jesper VIND, Lars Henrik OESTERGAARD, Leonardo DE MARIA, Lisbeth KALUM, Eleni AMOURGI
  • Phytase Variants
    Publication number: 20160362666
    Abstract: The present invention relates to a phytase which has at least 74% identity to a phytase derived from Citrobacter braakii and comprises at least one alteration as compared to this phytase. These phytase variants have amended, preferably improved, properties, such as thermostability, temperature profile, pH profile, specific activity, performance in animal feed, reduced protease sensibility, and/or an amended glycosylation pattern. The invention also relates to DNA encoding these phytases, methods of their production, as well as the use thereof, e.g., in animal feed and animal feed additives.
    Type: Application
    Filed: August 29, 2016
    Publication date: December 15, 2016
    Applicant: Novozymes A/S
    Inventors: Leonardo De Maria, Carsten Andersen, Lars Kobberoee Skov, Mikael Blom Soerensen
  • Cutinase Variants and Polynucleotides Encoding Same
    Publication number: 20160355759
    Abstract: Variants with cutinase activity of a parent cutinase, comprising an alteration at one or more (e.g. several) positions corresponding to positions: 181, 182, 115, 161, 1, 2, 43, 55, 79, or 5 of SEQ ID NO: 2, wherein the alteration is a substitution for positions 181, 115, 161, 43, 55, 79, and 5, and a deletion for positions 1, 2 and 182, and wherein the variant has at least 75% but less than 100% sequence identity to the mature polypeptide of SEQ ID NO: 2. Polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and method for obtaining and methods of producing the variants. Compositions comprising the variants and methods for using the variants.
    Type: Application
    Filed: December 10, 2014
    Publication date: December 8, 2016
    Applicant: Novozymes A/S
    Inventors: Leonardo De Maria, Rakhi Saikia, Santhosh Vasu Mepadam, Ting Sun
  • Polypeptides having organophosphorous hydrolase activity
    Patent number: 9512413
    Abstract: The present invention relates to isolated polypeptides having organophosphorous hydrolase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Grant
    Filed: May 31, 2013
    Date of Patent: December 6, 2016
    Assignee: NOVOZYMES A/S
    Inventors: Bjarne Gram Hansen, Steffen Danielsen, Lars Kobberoee Skov, Leonardo De Maria, Julie Bille Rannes
  • Organophosphorous Hydrolase Variants
    Publication number: 20160289654
    Abstract: The present invention relates to organophosphorous hydrolase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: November 28, 2014
    Publication date: October 6, 2016
    Applicant: Novozymes A/S
    Inventors: Bjarne G. Hansen, Lars Kobberoe Skov, Leonardo De Maria, Julie Bille Rannes
  • Thermostable Phytase Variants
    Publication number: 20160289655
    Abstract: The present invention relates to a phytase which has at least 70% identity to a phytase derived from E. coli and comprises at least one modification as compared to this phytase. These phytase variants have modified, preferably improved, properties, such as thermostability, temperature profile, pH profile, specific activity, performance in animal feed, reduced protease sensitiliby, and/or an modified glycosylation pattern. The invention also relates to DNA encoding these phytases, methods of their production, as well as the use thereof, e.g., in animal feed and animal feed additives.
    Type: Application
    Filed: June 17, 2016
    Publication date: October 6, 2016
    Applicant: Novozymes A/S
    Inventors: Leonardo De Maria, Lars Kobberoee Skov, Michael Skjoet
  • Phytase variants
    Patent number: 9451783
    Abstract: The present invention relates to a phytase which has at least 74% identity to a phytase derived from Citrobacter braakii and comprises at least one alteration as compared to this phytase. These phytase variants have amended, preferably improved, properties, such as thermostability, temperature profile, pH profile, specific activity, performance in animal feed, reduced protease sensitiliby, and/or an amended glycosylation pattern. The invention also relates to DNA encoding these phytases, methods of their production, as well as the use thereof, e.g., in animal feed and animal feed additives.
    Type: Grant
    Filed: October 2, 2014
    Date of Patent: September 27, 2016
    Assignee: NOVOZYMES A/S
    Inventors: Leonardo De Maria, Carsten Andersen, Lars Kobberoee Skov, Mikael Blom Soerensen
  • GLUCOAMYLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME
    Publication number: 20160230157
    Abstract: The present invention relates to glucoamylase variants having improved thermostability. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: April 26, 2016
    Publication date: August 11, 2016
    Applicant: NOVOZYMES A/S
    Inventors: Esben Peter Friis, Leonardo De Maria, Jesper Vind, Thomas A. Poulsen, Allan Svendsen, Steffen Danielsen, Rolf T. Lenhard, Henrik Friis-Madsen, Lars K. Skov
  • Dehydrogenase variants and polynucleotides encoding same
    Patent number: 9404091
    Abstract: The present invention relates to 3-hydroxypropionate dehydrogenase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: October 5, 2015
    Date of Patent: August 2, 2016
    Assignees: Novozymes, Inc., Novozymes A/S
    Inventors: Monica Tassone, Leonardo De Maria
  • Polypeptides having phytase activity and polynucleotides encoding same
    Patent number: 9365840
    Abstract: The present invention relates to polypeptides having phytase activity. These polypeptides have an amino acid sequence which has at least 70% identity to either of three phytases derived from the bacterium Buttiauxella, and which comprises at least one of the following amino acids at the position indicated: 119N, 120L, and/or 121E. These phytases have an improved specific activity. Additional specific amino acid substitutions are also disclosed which characterize and distinguish additional phytases of the invention having improved properties such as temperature and/or pH stability, pH activity profile, temperature activity profile, substrate profile, improved performance in animal feed in vitro or in vivo. The invention also relates to isolated polynucleotides encoding the polypeptides, nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: October 11, 2013
    Date of Patent: June 14, 2016
    Assignee: Novozymes A/S
    Inventors: Carsten Sjoeholm, Soeren Flensted Lassen, Lars Kobberoee Skov, Leonardo De Maria
  • Glucoamylase variants and polynucleotides encoding same
    Patent number: 9353362
    Abstract: The present invention relates to glucoamylase variants having improved thermostability. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: October 11, 2012
    Date of Patent: May 31, 2016
    Assignee: NOVOZYMES A/S
    Inventors: Esben Peter Friis, Leonardo De Maria, Jesper Vind, Thomas A. Poulsen, Allan Svendsen, Steffen Danielsen, Rolf T. Lenhard, Henrik Friis-Madsen, Lars K. Skov
  • GLUCOAMYLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME
    Publication number: 20160046916
    Abstract: The present invention relates to glucoamylase variants having increased thermostability. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: March 6, 2014
    Publication date: February 18, 2016
    Applicant: NOVOZYMES A/S
    Inventors: Esben P. Friis, Jesper Vind, Leonardo De Maria, Bjarne G. Hansen