Abstract: A method of binder jet additive manufacturing (BJAM) is provided. The method includes feeding a supply of powder particles to a powder bed, delivering an organic binder onto the powder bed in select locations of each layer to form a porous green part, and introducing to the binder a secondary component that chemically reacts with the binder to form a solid polymer matrix around the powder particles. The secondary component is introduced either by: (i) infiltration of the secondary component into the porous green part; or (ii) by combining the secondary component with the powder particles prior to feeding the powder particles to the powder bed. A binder system for BJAM is also provided. The binder system includes a reactive pair including an organic binder that is capable of being deposited on a powder bed; and a secondary component that is reactive with the organic binder.

Abstract: Provided in the present invention are a BCMA-targeting single-domain antibody and an encoding nucleotide sequence thereof. Also provided in the present invention are a multispecific antibody, a chimeric antigen receptor, and an antibody conjugate containing the BCMA single domain antibody, and a pharmaceutical composition and kit containing said antibodies, chimeric antigen receptor and antibody conjugate, and the use thereof in the diagnosis/treatment/prevention of diseases associated with BCMA expression.

Abstract: The present invention provides a CD19-targeting humanized antibody, and a multispecific antibody, chimeric receptor, antibody conjugate, pharmaceutical composition, and kit comprising the CD19-targeting humanized antibody, and a use thereof in the diagnosis/treatment/prevention of diseases associated with CD19 expression.

Abstract: Provided is a chimeric antigen receptor, comprising a ligand-binding domain, a transmembrane domain, a co-stimulatory domain, and an intracellular signaling domain. The co-stimulatory domain comprises an intracellular region of an NK-activated receptor or a ligand thereof. Also provided are an engineered immune cell comprising the chimeric antigen receptor and a use thereof in treatment of diseases, such as cancers, autoimmune diseases, and infections.

Abstract: Provided is an engineered immune cell. The engineered immune cell expresses (i) a chimeric receptor, and (ii) exogenous CCL3, CCL4 and/or CCL5, has improved tumor killing activity, and can be used to treat cancer, infection or autoimmune diseases.

Abstract: The present invention provides a CD7-targeting humanized antibody, and a multispecific antibody, chimeric antigen receptor, antibody conjugate, pharmaceutical composition, and kit comprising the CD7-targeting humanized antibody, and a use thereof in the diagnosis/treatment/prevention of diseases associated with CD7 expression.

Abstract: Provided is an engineered immune cell. The cell expresses a chimeric antigen receptor comprising an antigen-binding region. The antigen-binding region comprises an anti-CD7 antibody, and the expression of endogenous CD7, at least one TCR/CD3 gene, and at least one MHC-II related gene is suppressed or silenced. Further provided is the use of the engineered immune cell in the treatment of diseases associated with CD7 expression.

Abstract: Systems and methods for providing enterprise-level application content customization are described herein. A method includes executing an enterprise application (from a suite of enterprise applications that are utilized by the enterprise) on a remote computing system operated by an enterprise administrator. The method includes surfacing a content customization UI on a display device of the remote computing system during execution of the enterprise application. The content customization UI includes UI elements that enable the specification of parameters for providing enterprise-specific customized content during execution of enterprise application(s) from the suite of enterprise applications on remote computing system(s) operated by enterprise user(s). The method also includes receiving, via the content customization UI, user input including the specification of parameters and generating the customized content based on the specified parameters.

Abstract: A docking station includes a station body and a liquid feeding assembly. The station body has a docking region and guiding assembly on a side of the station body. The guiding assembly is in the docking region. The guiding assembly is configured to be in guiding fit with a mating assembly of a cleaning device. The liquid feeding assembly is on the station body and includes a liquid feeding connector. The liquid feeding connector has a liquid outlet oriented toward the docking region. The liquid outlet is configured to be butted and communicated with a connector of the cleaning device under the guiding fit of the guiding assembly and the mating assembly.

Abstract: Systems and methods for audio advertising user interaction are disclosed. A voice interactive device causes an advertising audio file to be played for a user. The user can express interest in the advertising content of the advertising audio file by speaking one of a plurality of predetermined intents. Based on expressed user response, one or more results can be provided to the user and/or to a user device. The results relate to advertising content of the advertising audio file.

Abstract: A method and a device for measuring a four-dimensional (4D) radiation pattern of an outdoor antenna based on an unmanned aerial vehicle (UAV) are provided. The device includes a measurement path planning unit, a UAV platform unit, a radiation signal acquisition unit, a data command processing unit, and a ground data processing unit. The measurement path planning unit, the radiation signal acquisition unit, and the data command processing unit each are suspended from the UAV platform unit by using a pod. The present disclosure applies to the radiation pattern measurement of an outdoor antenna.

Abstract: An action recognition system includes a controller that computes, in a time division manner, a plurality of feature vectors using as feature quantities information of a machine with respect to running that varies in a time sequence, generates a classification model by classifying the feature vectors into a plurality of clusters and allocating identification IDs to the clusters, generates an ID pattern model by allocating the identification IDs to the feature vectors computed in the time division manner on the basis of the classification model and associating a pattern of the identification IDs that vary in a time sequence according to a predetermined action of the machine with identification information of the predetermined action, generates output information for recognizing the predetermined action on the basis of changes in the identification IDs in the time sequence and the ID pattern model, and controls the display device to output the output information.

Abstract: Systems and methods for providing enterprise-level application content customization are described herein. A method includes executing an enterprise application (from a suite of enterprise applications that are utilized by the enterprise) on a remote computing system operated by an enterprise administrator. The method includes surfacing a content customization UI on a display device of the remote computing system during execution of the enterprise application. The content customization UI includes UI elements that enable the specification of parameters for providing enterprise-specific customized content during execution of enterprise application(s) from the suite of enterprise applications on remote computing system(s) operated by enterprise user(s). The method also includes receiving, via the content customization UI, user input including the specification of parameters and generating the customized content based on the specified parameters.

Abstract: A chimeric antigen receptor, containing a ligand binding domain, a transmembrane domain, a co-stimulatory domain, and an intracellular signaling domain, the co-stimulatory domain containing CD94 and/or LT? intracellular regions. The present invention further relates to engineered immune cells containing such a chimeric antigen receptor, and uses thereof in the treatment of diseases, such as cancer, autoimmune diseases, and infections.

Abstract: A method and a device for measuring a four-dimensional (4D) radiation pattern of an outdoor antenna based on an unmanned aerial vehicle (UAV) are provided. The device includes a measurement path planning unit, a UAV platform unit, a radiation signal acquisition unit, a data command processing unit, and a ground data processing unit. The measurement path planning unit, the radiation signal acquisition unit, and the data command processing unit each are suspended from the UAV platform unit by using a pod. The present disclosure applies to the radiation pattern measurement of an outdoor antenna.

Abstract: A reforming element for a molten carbonate fuel cell stack and corresponding methods are provided that can reduce or minimize temperature differences within the fuel cell stack when operating the fuel cell stack with enhanced CO2 utilization. The reforming element can include at least one surface with a reforming catalyst deposited on the surface. A difference between the minimum and maximum reforming catalyst density and/or activity on a first portion of the at least one surface can be 20% to 75%, with the highest catalyst densities and/or activities being in proximity to the side of the fuel cell stack corresponding to at least one of the anode inlet and the cathode inlet.

Abstract: Provided is an engineered immune cell. The expressions of at least one MHC related gene and at least one NK activating receptor binding molecule are suppressed or silenced, so as to suppress the killing of the engineered immune cell by NK cells. Also provided are a pharmaceutical composition comprising the engineered immune cell and use of the engineered immune cell in preparation of drugs for treatment of cancer, infection, or autoimmune diseases.

Abstract: A partition skirt device for a cleaning apparatus includes an inner ring and a skirt body. The skirt body includes: a root connected to the inner ring; an edge part arranged at an end of the skirt body away from the inner ring; and a plurality of collapsing parts arranged at intervals between the root and the edge part along a circumferential direction of the skirt body, and each extending along a radial direction of the skirt body. Along a thickness direction of the skirt body, the collapsing part protrudes relative to the skirt body on a first side surface of the skirt body and is recessed relative to the skirt body on a second side surface of the skirt body. On the first side surface of the skirt body, a size of a portion of the collapsing part protruding from the skirt body gradually decreases from the root to the edge part.

Abstract: A dust scraping device for a cleaning apparatus includes a dust cup and a removable cyclone separation unit arranged in the dust cup. The dust scraping device includes a dust scraping member. The dust scraping member has a connection portion extending in a removal direction of the cyclone separation unit, and a dust scraping portion extending to an interior of the dust cup in a direction perpendicular to the removal direction and slidably abutting against the cyclone separation unit. The dust scraping device is mounted at the dust cup, and the dust scraping portion scrapes off at least part of debris on an outer side of the cyclone separation unit when the cyclone separation unit is removed from the dust cup.

Abstract: Systems and methods are provided for improving the operation of molten carbonate fuel cells that include cathode current collector structures that have reduced contact area with the cathode in order to create increased cathode open surface area. Molten carbonate fuel cells that have cathode collectors with reduced contact area with the cathode can have an increased tendency to suffer structural difficulties during operation, such as formation of gaps between electrolyte and one or both electrodes. Use of a sintered anode in such a fuel cell can reduce or minimize the impact of such structural difficulties. The sintered anode can provide higher pore volume and/or a more stable pore structure and/or increased structural stability in a fuel cell that includes a cathode collector that has a reduced contact area with the cathode. This can maintain a more stable interface between the cathode and electrolyte and/or between the anode and the electrolyte.